Poonkuzhali Balasubramanian

Department of Clinical Haematology, Christian Medical College

Affiliated withChristian Medical College Thiruvalluvar University

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2022

Other Publications

Article	Year
A phase II study evaluating the role of bortezomib in the management of relapsed acute promyelocytic leukemia treated upfront with arsenic trioxide. Cancer medicine\| PubMed ID: 32059085	2020
JAK2 exon 12 mutations in cases with JAK2V617F-negative polycythemia vera and primary myelofibrosis. Annals of hematology\| PubMed ID: 32277273	2020
Arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: a single center experience. American journal of hematology\| PubMed ID: 12210810	2002
Rapid detection of beta-globin gene mutations and polymorphisms by temporal temperature gradient gel electrophoresis. Clinical chemistry\| PubMed ID: 12709369	2003
Glutathione S-transferase M1 polymorphism: a risk factor for hepatic venoocclusive disease in bone marrow transplantation. Blood\| PubMed ID: 15142875	2004
Cytochrome P4501A1 and glutathione S transferase gene polymorphisms in patients with aplastic anemia in India. Acta haematologica\| PubMed ID: 16227674	2005
Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: durable remissions with minimal toxicity. Blood\| PubMed ID: 16352810	2006
Identification of compounds that correlate with ABCG2 transporter function in the National Cancer Institute Anticancer Drug Screen. Molecular pharmacology\| PubMed ID: 19633067	2009
Comparison of clinical outcomes of patients with relapsed acute promyelocytic leukemia induced with arsenic trioxide and consolidated with either an autologous stem cell transplant or an ars... Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 19822309	2009
Frequency of TPMT alleles in Indian patients with acute lymphatic leukemia and effect on the dose of 6-mercaptopurine. Medical oncology (Northwood, London, England)\| PubMed ID: 19830600	2010
Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: long-term follow-up data. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 20644086	2010
The t(6;9)(p22;q34) in myeloid neoplasms: a retrospective study of 16 cases. Cancer genetics and cytogenetics\| PubMed ID: 21156248	2010
Cytogenetic analysis of acute myeloid leukemia with t(8;21) from a tertiary care center in India with correlation between clinicopathologic characteristics and molecular analysis. Leukemia & lymphoma\| PubMed ID: 21745004	2012
Population pharmacokinetics of cyclophosphamide in patients with thalassemia major undergoing HSCT. Bone marrow transplantation\| PubMed ID: 22231460	2012
International reporting scale of BCR-ABL1 fusion transcript in chronic myeloid leukemia: first report from India. Acta haematologica\| PubMed ID: 22249155	2012
Cytidine deaminase genetic variants influence RNA expression and cytarabine cytotoxicity in acute myeloid leukemia. Pharmacogenomics\| PubMed ID: 22304580	2012
Role of minimal residual disease monitoring in acute promyelocytic leukemia treated with arsenic trioxide in frontline therapy. Blood\| PubMed ID: 22374701	2012
Carbonyl reductase 1 expression influences daunorubicin metabolism in acute myeloid leukemia. European journal of clinical pharmacology\| PubMed ID: 22562609	2012
Clinical predictors of serum clozapine levels in patients with treatment-resistant schizophrenia. International clinical psychopharmacology\| PubMed ID: 23104241	2013
Role of imatinib in the treatment of pediatric onset indolent systemic mastocytosis: a case report. The Journal of dermatological treatment\| PubMed ID: 23659595	2013
A rapid & sensitive liquid chromatography- tandem mass spectrometry method for the quantitation of busulfan levels in plasma & application for routine therapeutic monitoring in haematopoieti... The Indian journal of medical research\| PubMed ID: 23703347	2013
ABCB6 RNA expression in leukemias--expression is low in acute promyelocytic leukemia and FLT3-ITD-positive acute myeloid leukemia. Annals of hematology\| PubMed ID: 23793916	2014
Genetic association between the DRD4 promoter polymorphism and clozapine-induced sialorrhea. Psychiatric genetics\| PubMed ID: 25304228	2014
Effect of cytosine arabinoside metabolizing enzyme expression on drug toxicity in acute myeloid leukemia. Annals of hematology\| PubMed ID: 25391240	2015
V-raf murine sarcoma viral oncogene homolog B (BRAF) mutations in hairy cell leukaemia. Indian journal of pathology & microbiology\| PubMed ID: 25673595	2015
Comparison of newly diagnosed and relapsed patients with acute promyelocytic leukemia treated with arsenic trioxide: insight into mechanisms of resistance. PloS one\| PubMed ID: 25822503	2015
Acute myeloid leukaemia: challenges and real world data from India. British journal of haematology\| PubMed ID: 25858293	2015
RNA expression of genes involved in cytarabine metabolism and transport predicts cytarabine response in acute myeloid leukemia. Pharmacogenomics\| PubMed ID: 26083014	2015
Treatment rates of paediatric acute myeloid leukaemia: a view from three tertiary centres in India - response to Gupta et al. British journal of haematology\| PubMed ID: 26627639	2016
Atypical BCR-ABL1 fusion transcripts in adult B-acute lymphoblastic leukemia, including a novel fusion transcript-e8a1. Leukemia & lymphoma\| PubMed ID: 26942999	2016
Population pharmacokinetics of Daunorubicin in adult patients with acute myeloid leukemia. Cancer chemotherapy and pharmacology\| PubMed ID: 27738808	2016
ATP-binding casette transporter expression in acute myeloid leukemia: association with in vitro cytotoxicity and prognostic markers. Pharmacogenomics\| PubMed ID: 28112576	2017
Role of NF-E2 related factor 2 (Nrf2) on chemotherapy resistance in acute myeloid leukemia (AML) and the effect of pharmacological inhibition of Nrf2. PloS one\| PubMed ID: 28505160	2017
Allogeneic Stem Cell Transplant for Acute Myeloid Leukemia: Evolution of an Effective Strategy in India. Journal of global oncology\| PubMed ID: 29244983	2017
Pharmacokinetics and Pharmacodynamics of Treosulfan in Patients With Thalassemia Major Undergoing Allogeneic Hematopoietic Stem Cell Transplantation. Clinical pharmacology and therapeutics\| PubMed ID: 29247522	2018
Arsenic Trioxide Enhances the NK Cell Cytotoxicity Against Acute Promyelocytic Leukemia While Simultaneously Inhibiting Its Bio-Genesis. Frontiers in immunology\| PubMed ID: 29963052	2018
Correction: Population pharmacokinetics of fludarabine in patients with aplastic anemia and Fanconi anemia undergoing allogeneic hematopoietic stem cell transplantation. Bone marrow transplantation\| PubMed ID: 30135463	2018
Spectrum of mutations in congenital neutropenia: a single-centre study in patients of Indian origin. Journal of clinical pathology\| PubMed ID: 30171085	2018
Adult Acute Lymphoblastic Leukemia: Limitations of Intensification of Therapy in a Developing Country. Journal of global oncology\| PubMed ID: 30222028	2018
Allele Specific PCR: A Cost Effective Screening Method for MPL Mutations in Myeloproliferative Neoplasms. Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion\| PubMed ID: 30369762	2018
Applications of Next Generation Sequencing in Haematological Disorders-Indian Status: Updates from ISHBT 2018. Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion\| PubMed ID: 30828142	2019
A personalized approach to acute myeloid leukemia therapy: current options. Pharmacogenomics and personalized medicine\| PubMed ID: 31447578	2019
Stromal cells downregulate miR-23a-5p to activate protective autophagy in acute myeloid leukemia. Cell death & disease\| PubMed ID: 31570693	2019
In Ph+BCR-ABL1 acute lymphoblastic leukemia the e13a2 (B2A2) transcript is prevalent. Leukemia\| PubMed ID: 31595038	2020
Screening of genetic variants in mutation negative congenital neutropenia by next generation sequencing. Journal of clinical pathology\| PubMed ID: 31732620	2020
Pharmacokinetics and Efficacy of Generic Melphalan Is Comparable to Innovator Formulation in Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplantation. Clinical lymphoma, myeloma & leukemia\| PubMed ID: 31791694	2020
Resource utilization and cost effectiveness of treating acute promyelocytic leukaemia using generic arsenic trioxide. British journal of haematology\| PubMed ID: 31863602	2020
NUDT15 polymorphism explains serious toxicity to azathioprine in Indian patients with chronic immune thrombocytopenia and autoimmune hemolytic anemia: a case series. Drug metabolism and personalized therapy\| PubMed ID: 32827393	2020
Prognostic value of MRD monitoring based on copy numbers in Philadelphia chromosome positive acute lymphoblastic leukemia. Leukemia & lymphoma\| PubMed ID: 32852239	2020
Prognostic plasma biomarkers of early complications and graft-versus-host disease in patients undergoing allogeneic hematopoietic stem cell transplantation. EJHaem\| PubMed ID: 32885223	2020
Management of relapse in acute promyelocytic leukaemia treated with up-front arsenic trioxide-based regimens. British journal of haematology\| PubMed ID: 33216980	2021
Plasma imatinib levels and ABCB1 polymorphism influences early molecular response and failure-free survival in newly diagnosed chronic phase CML patients. Scientific reports\| PubMed ID: 33244077	2020
kinase domain mutation analysis by next generation sequencing detected additional mutations in chronic myeloid leukemia patients with suboptimal response to imatinib. Leukemia & lymphoma\| PubMed ID: 33478278	2021
Mutation profile in BCR-ABL1-negative myeloproliferative neoplasms: A single-center experience from India. Hematology/oncology and stem cell therapy\| PubMed ID: 33789164	2021
Direct Generation of Immortalized Erythroid Progenitor Cell Lines from Peripheral Blood Mononuclear Cells. Cells\| PubMed ID: 33804564	2021
Systematic application of fluorescence in situ hybridization and immunophenotype profile for the identification of ZNF384 gene rearrangements in B cell acute lymphoblastic leukemia. International journal of laboratory hematology\| PubMed ID: 33988307	2021
Cholesterol Sequestration from Caveolae/Lipid Rafts Enhances Cationic Liposome-Mediated Nucleic Acid Delivery into Endothelial Cells. Molecules (Basel, Switzerland)\| PubMed ID: 34361779	2021
Calreticulin Immunohistochemistry in Myeloproliferative Neoplasms - Evolution of a New Cost-Effective Diagnostic Tool: A Retrospective Study with Histological and Molecular Correlation. Turk patoloji dergisi\| PubMed ID: 34514582	2022
Metabolic adaptation drives arsenic trioxide resistance in acute promyelocytic leukemia. Blood advances\| PubMed ID: 34625794	2022
c.415C>T Polymorphism Predicts 6-MP Induced Early Myelotoxicity in Patients with Acute Lymphoblastic Leukemia Undergoing Maintenance Therapy. Pharmacogenomics and personalized medicine\| PubMed ID: 34629890	2021
Clinicopathological Profile of Childhood Onset Cutaneous Mastocytosis from a Tertiary Care Center in South India. Indian dermatology online journal\| PubMed ID: 34667757	2021
Real world data with concurrent retinoic acid and arsenic trioxide for the treatment of acute promyelocytic leukemia. Blood cancer journal\| PubMed ID: 35102152	2022
Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin. eLife\| PubMed ID: 35147495	2022
Endothelial Activation and Stress Index-Measured Pretransplantation Predicts Transplantation-Related Mortality in Patients with Thalassemia Major Undergoing Transplantation with Thiotepa, Tr... Transplantation and cellular therapy\| PubMed ID: 35550442	2022