Clive N. May

Florey Institute of Neuroscience and Mental Health, University of Melbourne

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2021

Other Publications

Article	Year
Direct cardiac and vascular actions of adrenomedullin in conscious sheep. British journal of pharmacology\| PubMed ID: 9134233	1997
Aldosterone acts on the kidney, not the brain, to cause mineralocorticoid hypertension in sheep. Journal of hypertension\| PubMed ID: 12023692	2002
Urotensin II acts centrally to increase epinephrine and ACTH release and cause potent inotropic and chronotropic actions. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 12885791	2003
Stimulation of cardiac sympathetic nerve activity by central angiotensinergic mechanisms in conscious sheep. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 14751846	2004
Selective vasodilator and chronotropic actions of 3',4'-dihydroxyflavonol in conscious sheep. European journal of pharmacology\| PubMed ID: 15102532	2004
3',4'-Dihydroxyflavonol reduces infarct size and injury associated with myocardial ischaemia and reperfusion in sheep. British journal of pharmacology\| PubMed ID: 15148246	2004
Oxytocinase/insulin-regulated aminopeptidase is distributed throughout the sheep, female reproductive tract and is regulated by oestrogen in the uterus. Regulatory peptides\| PubMed ID: 15380925	2004
Urotensin II, a novel peptide in central and peripheral cardiovascular control. Peptides\| PubMed ID: 15476943	2004
The haemodynamic and metabolic effects of epinephrine in experimental hyperdynamic septic shock. Intensive care medicine\| PubMed ID: 15711973	2005
Differential regional haemodynamic changes during mineralocorticoid hypertension. Journal of hypertension\| PubMed ID: 16685214	2006
Renal vascular resistance in sepsis. Nephron. Physiology\| PubMed ID: 16691034	2006
The effect of normal saline resuscitation on vital organ blood flow in septic sheep. Intensive care medicine\| PubMed ID: 16775719	2006
Urinary biomarkers in septic acute kidney injury. Intensive care medicine\| PubMed ID: 17487471	2007
The histopathology of septic acute kidney injury: a systematic review. Critical care (London, England)\| PubMed ID: 18325092	2008
Responses of cardiac sympathetic nerve activity to changes in circulating volume differ in normal and heart failure sheep. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 18635453	2008
Basis for the preferential activation of cardiac sympathetic nerve activity in heart failure. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19136635	2009
Septic shock induces distinct changes in sympathetic nerve activity to the heart and kidney in conscious sheep. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 19726712	2009
3',4'-Dihydroxyflavonol improves post-ischaemic coronary endothelial function following 7days reperfusion in sheep. European journal of pharmacology\| PubMed ID: 19825372	2009
Frontiers in research series: Neural, hormonal and renal interactions in long-term blood pressure control II. Introduction. Clinical and experimental pharmacology & physiology\| PubMed ID: 19930420	2010
Angiotensin II in experimental hyperdynamic sepsis. Critical care (London, England)\| PubMed ID: 19948019	2009
The impact of experimental hypoperfusion on subsequent kidney function. Intensive care medicine\| PubMed ID: 20049587	2010
Response of cardiac sympathetic nerve activity to intravenous irbesartan in heart failure. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 20147604	2010
Early and sustained systemic and renal hemodynamic effects of intravenous radiocontrast. Blood purification\| PubMed ID: 20357433	2010
Hypertonic sodium resuscitation after hemorrhage improves hemodynamic function by stimulating cardiac, but not renal, sympathetic nerve activity. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 21148761	2011
The impact of intrarenal nitric oxide synthase inhibition on renal blood flow and function in mild and severe hyperdynamic sepsis. Critical care medicine\| PubMed ID: 21169816	2011
Cardioprotection from ischaemia-reperfusion injury by a novel flavonol that reduces activation of p38 MAPK. European journal of pharmacology\| PubMed ID: 21371449	2011
Renal bioenergetics during early gram-negative mammalian sepsis and angiotensin II infusion. Intensive care medicine\| PubMed ID: 22302028	2012
Central angiotensin type 1 receptor blockade decreases cardiac but not renal sympathetic nerve activity in heart failure. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 22311902	2012
The effects of terlipressin on regional hemodynamics and kidney function in experimental hyperdynamic sepsis. PloS one\| PubMed ID: 22355305	2012
The role of the paraventricular nucleus of the hypothalamus in the regulation of cardiac and renal sympathetic nerve activity in conscious normal and heart failure sheep. The Journal of physiology\| PubMed ID: 22615431	2013
Effect of selective inhibition of renal inducible nitric oxide synthase on renal blood flow and function in experimental hyperdynamic sepsis. Critical care medicine\| PubMed ID: 22622397	2012
Pulmonary Artery Catheter (PAC) Accuracy and Efficacy Compared with Flow Probe and Transcutaneous Doppler (USCOM): An Ovine Cardiac Output Validation. Critical care research and practice\| PubMed ID: 22649718	2012
Novel targets for sepsis-induced kidney injury: the glomerular arterioles and the sympathetic nervous system. Experimental physiology\| PubMed ID: 22689445	2012
Cardiac sympathoexcitation in heart failure. Autonomic neuroscience : basic & clinical\| PubMed ID: 23332860	2013
Organ selective regulation of sympathetic outflow by the brain Angiotensin system. Current hypertension reports\| PubMed ID: 23681510	2013
Cardioprotective 3',4'-dihydroxyflavonol attenuation of JNK and p38(MAPK) signalling involves CaMKII inhibition. The Biochemical journal\| PubMed ID: 24032640	2013
Renal histopathology during experimental septic acute kidney injury and recovery. Critical care medicine\| PubMed ID: 24126439	2014
Intracarotid hypertonic sodium chloride differentially modulates sympathetic nerve activity to the heart and kidney. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 24523342	2014
Systemic and renal haemodynamic effects of fluid bolus therapy: sodium chloride versus sodium octanoate-balanced solution. Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine\| PubMed ID: 24588433	2014
Glomerular haemodynamics, the renal sympathetic nervous system and sepsis-induced acute kidney injury. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 24619060	2014
Effects of renal denervation on regional hemodynamics and kidney function in experimental hyperdynamic sepsis. Critical care medicine\| PubMed ID: 24670939	2014
Role of prostaglandins in determining the increased cardiac sympathetic nerve activity in ovine sepsis. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 24789991	2014
Central exogenous nitric oxide decreases cardiac sympathetic drive and improves baroreflex control of heart rate in ovine heart failure. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 24848361	2014
Tonic arterial chemoreceptor activity contributes to cardiac sympathetic activation in mild ovine heart failure. Experimental physiology\| PubMed ID: 24928955	2014
The low frequency power of heart rate variability is neither a measure of cardiac sympathetic tone nor of baroreflex sensitivity. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 25063795	2014
Reinnervation of renal afferent and efferent nerves at 5.5 and 11 months after catheter-based radiofrequency renal denervation in sheep. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 25403610	2015
Effects of selective β1-adrenoceptor blockade on cardiovascular and renal function and circulating cytokines in ovine hyperdynamic sepsis. Critical care (London, England)\| PubMed ID: 25413250	2014
Reply to "Letter to the editor: Does low-frequency power of heart rate variability correlate with cardiac sympathetic tone in normal sheep?". American journal of physiology. Heart and circulatory physiology\| PubMed ID: 25552630	2015
Reinnervation following catheter-based radio-frequency renal denervation. Experimental physiology\| PubMed ID: 25573386	2015
Long-term measurement of renal cortical and medullary tissue oxygenation and perfusion in unanesthetized sheep. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 25761701	2015
Evidence that the MEK/ERK but not the PI3K/Akt pathway is required for protection from myocardial ischemia-reperfusion injury by 3',4'-dihydroxyflavonol. European journal of pharmacology\| PubMed ID: 25820159	2015
Clonidine Restores Pressor Responsiveness to Phenylephrine and Angiotensin II in Ovine Sepsis. Critical care medicine\| PubMed ID: 25860204	2015
Cortical and Medullary Tissue Perfusion and Oxygenation in Experimental Septic Acute Kidney Injury. Critical care medicine\| PubMed ID: 26181218	2015
Acid-base changes after fluid bolus: sodium chloride vs. sodium octanoate. Intensive care medicine experimental\| PubMed ID: 26266792	2013
Systemic and renal hemodynamic effects of intra-arterial radiocontrast. Intensive care medicine experimental\| PubMed ID: 26266929	2014
Variable responses of regional renal oxygenation and perfusion to vasoactive agents in awake sheep. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 26354843	2015
Role of endothelin-1 in mediating changes in cardiac sympathetic nerve activity in heart failure. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 26468257	2016
The role of the renal afferent and efferent nerve fibers in heart failure. Frontiers in physiology\| PubMed ID: 26483699	2015
Minimally invasive endovascular stent-electrode array for high-fidelity, chronic recordings of cortical neural activity. Nature biotechnology\| PubMed ID: 26854476	2016
Intrarenal and urinary oxygenation during norepinephrine resuscitation in ovine septic acute kidney injury. Kidney international\| PubMed ID: 27165831	2016
Chronic impedance spectroscopy of an endovascular stent-electrode array. Journal of neural engineering\| PubMed ID: 27378157	2016
Catheter-Based Renal Denervation Exacerbates Blood Pressure Fall During Hemorrhage. Journal of the American College of Cardiology\| PubMed ID: 28231948	2017
Recording sympathetic nerve activity in conscious humans and other mammals: guidelines and the road to standardization. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 28364017	2017
An ovine model of cerebral catheter venography for implantation of an endovascular neural interface. Journal of neurosurgery\| PubMed ID: 28452616	2018
The ovine motor cortex: A review of functional mapping and cytoarchitecture. Neuroscience and biobehavioral reviews\| PubMed ID: 28595827	2017
Circumventing a broken heart: cytokines and the subfornical organ. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 28778916	2017
Urinary Oxygenation as a Surrogate Measure of Medullary Oxygenation During Angiotensin II Therapy in Septic Acute Kidney Injury. Critical care medicine\| PubMed ID: 29077618	2018
Differential effects of isotonic and hypotonic 4% albumin solution on intracranial pressure and renal perfusion and function. Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine\| PubMed ID: 29458321	2018
An Ovine Model for Studying the Pathophysiology of Septic Acute Kidney Injury. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29468594	2018
Effects of Clonidine on the Cardiovascular, Renal, and Inflammatory Responses to Experimental Bacteremia. Shock (Augusta, Ga.)\| PubMed ID: 29489737	2019
Role of the Sympathetic Nervous System and Its Modulation in Renal Hypertension. Frontiers in medicine\| PubMed ID: 29651418	2018
Mechanisms underlying the increased cardiac norepinephrine spillover in heart failure. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 29701999	2018
Adeno-Associated Virus Gene Therapy: Translational Progress and Future Prospects in the Treatment of Heart Failure. Heart, lung & circulation\| PubMed ID: 29703647	2018
Signal quality of simultaneously recorded endovascular, subdural and epidural signals are comparable. Scientific reports\| PubMed ID: 29849104	2018
Sepsis-induced acute kidney injury: A disease of the microcirculation. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 29908046	2019
Zinc preconditioning protects against renal ischaemia reperfusion injury in a preclinical sheep large animal model. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine\| PubMed ID: 29974287	2018
Increased cardiac sympathetic nerve activity in ovine heart failure is reduced by lesion of the area postrema, but not lamina terminalis. Basic research in cardiology\| PubMed ID: 30076468	2018
Alterations in regional kidney oxygenation during expansion of extracellular fluid volume in conscious healthy sheep. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 30332304	2018
In renovascular hypertension, TNF-α type-1 receptors in the area postrema mediate increases in cardiac and renal sympathetic nerve activity and blood pressure. Cardiovascular research\| PubMed ID: 30358805	2019
Effects of Fluid Bolus Therapy on Renal Perfusion, Oxygenation, and Function in Early Experimental Septic Kidney Injury. Critical care medicine\| PubMed ID: 30394921	2019
Author Correction: Signal quality of simultaneously recorded endovascular, subdural and epidural signals are comparable. Scientific reports\| PubMed ID: 30478430	2018
Sustained Decrease in Blood Pressure and Reduced Anatomical and Functional Reinnervation of Renal Nerves in Hypertensive Sheep 30 Months After Catheter-Based Renal Denervation. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 30661475	2019
Renal perfusion, oxygenation, and sympathetic nerve activity during volatile or intravenous general anaesthesia in sheep. British journal of anaesthesia\| PubMed ID: 30770052	2019
Renal Cortical Perfusion, Measured by Superb Microvascular Imaging, during Infusion of Norepinephrine in Experimental Cardiopulmonary Bypass. American journal of respiratory and critical care medicine\| PubMed ID: 30785769	2019
Carotid artery and cerebral blood flow during experimental cardiopulmonary resuscitation: A systematic review of the literature. Resuscitation\| PubMed ID: 30797862	2019
Strategies that improve renal medullary oxygenation during experimental cardiopulmonary bypass may mitigate postoperative acute kidney injury. Kidney international\| PubMed ID: 31005272	2019
Focal stimulation of the sheep motor cortex with a chronically implanted minimally invasive electrode array mounted on an endovascular stent. Nature biomedical engineering\| PubMed ID: 31015727	2018
Factors that confound the prediction of renal medullary oxygenation and risk of acute kidney injury from measurement of bladder urine oxygen tension. Acta physiologica (Oxford, England)\| PubMed ID: 31066975	2019
Furosemide reverses medullary tissue hypoxia in ovine septic acute kidney injury. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 31141418	2019
Blunted diuretic and natriuretic responses to acute sodium loading early after catheter-based renal denervation in normotensive sheep. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 31166691	2019
Renal Denervation Update From the International Sympathetic Nervous System Summit: JACC State-of-the-Art Review. Journal of the American College of Cardiology\| PubMed ID: 31196459	2019
Neurohumoral interactions contributing to renal vasoconstriction and decreased renal blood flow in heart failure. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 31241978	2019
Effect of Furosemide on Urinary Oxygenation in Patients with Septic Shock. Blood purification\| PubMed ID: 31336370	2019
Intrathecal Administration of Losartan Reduces Directly Recorded Cardiac Sympathetic Nerve Activity in Ovine Heart Failure. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 31378100	2019
Chemoattraction and Recruitment of Activated Immune Cells, Central Autonomic Control, and Blood Pressure Regulation. Frontiers in physiology\| PubMed ID: 31427987	2019
Dexmedetomidine reduces norepinephrine requirements and preserves renal oxygenation and function in ovine septic acute kidney injury. Kidney international\| PubMed ID: 31530477	2019
Renal hemodynamics and oxygenation during experimental cardiopulmonary bypass in sheep under total intravenous anesthesia. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 31823674	2020
Renal Medullary Hypoxia: A New Therapeutic Target for Septic Acute Kidney Injury? Seminars in nephrology\| PubMed ID: 31836037	2019
Systemic administration of pentoxifylline attenuates the development of hypertension in renovascular hypertensive rats. Hypertension research : official journal of the Japanese Society of Hypertension\| PubMed ID: 32060380	2020
Systemic haemodynamic, renal perfusion and renal oxygenation responses to changes in inspired oxygen fraction during total intravenous or volatile anaesthesia. British journal of anaesthesia\| PubMed ID: 32563492	2020
Sympathetic nerves control bacterial clearance. Scientific reports\| PubMed ID: 32929135	2020
Beneficial Effects of Vasopressin Compared With Norepinephrine on Renal Perfusion, Oxygenation, and Function in Experimental Septic Acute Kidney Injury. Critical care medicine\| PubMed ID: 32931198	2020
Renal functional reserve: from physiological phenomenon to clinical biomarker and beyond. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 33074016	2020
Motor neuroprosthesis implanted with neurointerventional surgery improves capacity for activities of daily living tasks in severe paralysis: first in-human experience. Journal of neurointerventional surgery\| PubMed ID: 33115813	2021
Selective optogenetic stimulation of efferent fibers in the vagus nerve of a large mammal. Brain stimulation\| PubMed ID: 33217609	2021
Influence of blood haemoglobin concentration on renal haemodynamics and oxygenation during experimental cardiopulmonary bypass in sheep. Acta physiologica (Oxford, England)\| PubMed ID: 33222404	2021
Reversal of the Pathophysiological Responses to Gram-Negative Sepsis by Megadose Vitamin C. Critical care medicine\| PubMed ID: 33239507	2021
Emerging benefits and drawbacks of α -adrenoceptor agonists in the management of sepsis and critical illness. British journal of pharmacology\| PubMed ID: 33450087	2021
Increase in Bioavailability of Nitric Oxide After Renal Denervation Improves Kidney Function in Sheep With Hypertensive Kidney Disease. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 33641371	2021
The authors reply. Critical care medicine\| PubMed ID: 33731636	2021
Urinary and renal oxygenation during dexmedetomidine infusion in critically ill adults with mechanistic insights from an ovine model. Journal of critical care\| PubMed ID: 33794470	2021
Dynamic responses of renal oxygenation at the onset of cardiopulmonary bypass in sheep and man. Perfusion\| PubMed ID: 33977810	2021
Therapeutic potential of megadose vitamin C to reverse organ dysfunction in sepsis and COVID-19. British journal of pharmacology\| PubMed ID: 34061355	2021
Blunted natriuretic response to saline loading in sheep with hypertensive kidney disease following radiofrequency catheter-based renal denervation. Scientific reports\| PubMed ID: 34285286	2021
Renal, Cardiac, and Autonomic Effects of Catheter-Based Renal Denervation in Ovine Heart Failure. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 34333989	2021
Reversal of renal tissue hypoxia during experimental cardiopulmonary bypass in sheep by increased pump flow and arterial pressure. Acta physiologica (Oxford, England)\| PubMed ID: 34347356	2021
Targeting Oxidative Stress in Septic Acute Kidney Injury: From Theory to Practice. Journal of clinical medicine\| PubMed ID: 34501245	2021
Renal Denervation in Combination With Angiotensin Receptor Blockade Prolongs Blood Pressure Trough During Hemorrhage. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 34739764	2021