Peter J. Roy

Department of Molecular Genetics, University of Toronto

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2022

Other Publications

Article	Year
The forkhead transcription factor UNC-130 is required for the graded spatial expression of the UNC-129 TGF-beta guidance factor in C. elegans. Genes & development\| PubMed ID: 11018016	2000
Muscle arm development in Caenorhabditis elegans. Development (Cambridge, England)\| PubMed ID: 15930100	2005
Network news: functional modules revealed during early embryogenesis in C. elegans. Developmental cell\| PubMed ID: 16139218	2005
FGF negatively regulates muscle membrane extension in Caenorhabditis elegans. Development (Cambridge, England)\| PubMed ID: 16495308	2006
A small-molecule screen in C. elegans yields a new calcium channel antagonist. Nature\| PubMed ID: 16672971	2006
High-throughput screening of small molecules for bioactivity and target identification in Caenorhabditis elegans. Nature protocols\| PubMed ID: 17487175	2006
Cell-specific microarray profiling experiments reveal a comprehensive picture of gene expression in the C. elegans nervous system. Genome biology\| PubMed ID: 17612406	2007
A global analysis of genetic interactions in Caenorhabditis elegans. Journal of biology\| PubMed ID: 17897480	2007
Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen. PLoS genetics\| PubMed ID: 18454192	2008
A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans. Nature chemical biology\| PubMed ID: 20512140	2010
MADD-2, a homolog of the Opitz syndrome protein MID1, regulates guidance to the midline through UNC-40 in Caenorhabditis elegans. Developmental cell\| PubMed ID: 20627078	2010
MADD-4 is a secreted cue required for midline-oriented guidance in Caenorhabditis elegans. Developmental cell\| PubMed ID: 22014523	2011
Compound prioritization methods increase rates of chemical probe discovery in model organisms. Chemistry & biology\| PubMed ID: 22035796	2011
Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans. Nature chemical biology\| PubMed ID: 22057127	2011
Orthosteric and allosteric drug binding sites in the Caenorhabditis elegans mgl-2 metabotropic glutamate receptor. Neuropharmacology\| PubMed ID: 22652059	2012
EVA-1 functions as an UNC-40 Co-receptor to enhance attraction to the MADD-4 guidance cue in Caenorhabditis elegans. PLoS genetics\| PubMed ID: 25122090	2014
Caenorhabditis elegans is a useful model for anthelmintic discovery. Nature communications\| PubMed ID: 26108372	2015
The MADD-3 LAMMER Kinase Interacts with a p38 MAP Kinase Pathway to Regulate the Display of the EVA-1 Guidance Receptor in Caenorhabditis elegans. PLoS genetics\| PubMed ID: 27123983	2016
The novel nematicide wact-86 interacts with aldicarb to kill nematodes. PLoS neglected tropical diseases\| PubMed ID: 28379972	2017
The marginal cells of the Caenorhabditis elegans pharynx scavenge cholesterol and other hydrophobic small molecules. Nature communications\| PubMed ID: 31477732	2019
Author Correction: Caenorhabditis elegans is a useful model for anthelmintic discovery. Nature communications\| PubMed ID: 32709866	2020
A survey of the kinome pharmacopeia reveals multiple scaffolds and targets for the development of novel anthelmintics. Scientific reports\| PubMed ID: 33911106	2021