Giovanna Tosato

Laboratory of Cellular Oncology, National Institutes of Health

Affiliated withNational Institutes of Health

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2022

Other Publications

Article	Year
B cell differentiation and immunoregulatory T cell function in human cord blood lymphocytes. The Journal of clinical investigation\| PubMed ID: 6249850	1980
Interferon-inducible protein-10 identified as a mediator of tumor necrosis in vivo. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 8943014	1996
Interleukin-18, interferon-gamma, IP-10, and Mig expression in Epstein-Barr virus-induced infectious mononucleosis and posttransplant lymphoproliferative disease. The American journal of pathology\| PubMed ID: 10393857	1999
Laminin binding to the calreticulin fragment vasostatin regulates endothelial cell function. Journal of leukocyte biology\| PubMed ID: 11781379	2002
Anti-tumor activities of the angiogenesis inhibitors interferon-inducible protein-10 and the calreticulin fragment vasostatin. Cancer immunology, immunotherapy : CII\| PubMed ID: 12192535	2002
Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma. Blood\| PubMed ID: 12393476	2003
Pathogenesis and manifestations of human herpesvirus-8-associated disorders. Seminars in hematology\| PubMed ID: 12704591	2003
Viral and cellular cytokines as therapeutic targets in AIDS-related lymphoproliferative disorders. Current drug targets. Cardiovascular & haematological disorders\| PubMed ID: 12769647	2003
Targeted inhibition of angiogenic factors in AIDS-related disorders. Current drug targets. Infectious disorders\| PubMed ID: 12769789	2003
Selective expression of stromal-derived factor-1 in the capillary vascular endothelium plays a role in Kaposi sarcoma pathogenesis. Blood\| PubMed ID: 12907452	2003
Insulin-like growth factor I induces migration and invasion of human multiple myeloma cells. Blood\| PubMed ID: 14504085	2004
Differential processing of stromal-derived factor-1alpha and stromal-derived factor-1beta explains functional diversity. Blood\| PubMed ID: 14525775	2004
HIV-1 Tat enhances Kaposi sarcoma-associated herpesvirus (KSHV) infectivity. Blood\| PubMed ID: 15073028	2004
Derivation of endothelial cells from CD34- umbilical cord blood. Stem cells (Dayton, Ohio)\| PubMed ID: 15153615	2004
Therapeutic options for human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus-related disorders. Expert review of anti-infective therapy\| PubMed ID: 15482187	2004
Neuropilin-1 regulates attachment in human endothelial cells independently of vascular endothelial growth factor receptor-2. Blood\| PubMed ID: 15522955	2005
Neoplastic conditions in the context of HIV-1 infection. Current HIV research\| PubMed ID: 15544455	2004
Role of human cripto-1 in tumor angiogenesis. Journal of the National Cancer Institute\| PubMed ID: 15657343	2005
Identification of carboxypeptidase N as an enzyme responsible for C-terminal cleavage of stromal cell-derived factor-1alpha in the circulation. Blood\| PubMed ID: 15718415	2005
B-cell recovery following rituximab-based therapy is associated with perturbations in stromal derived factor-1 and granulocyte homeostasis. Blood\| PubMed ID: 15718416	2005
Therapy insight: AIDS-related malignancies--the influence of antiviral therapy on pathogenesis and management. Nature clinical practice. Oncology\| PubMed ID: 16130937	2005
Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function. Blood\| PubMed ID: 16219802	2006
Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A. Blood\| PubMed ID: 16424390	2006
Activity of subcutaneous interleukin-12 in AIDS-related Kaposi sarcoma. Blood\| PubMed ID: 16507779	2006
G-CSF down-regulation of CXCR4 expression identified as a mechanism for mobilization of myeloid cells. Blood\| PubMed ID: 16537807	2006
EphB2 and EphB4 receptors forward signaling promotes SDF-1-induced endothelial cell chemotaxis and branching remodeling. Blood\| PubMed ID: 16840724	2006
FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc. Blood\| PubMed ID: 17077327	2007
Transcription factor Gfi-1 induced by G-CSF is a negative regulator of CXCR4 in myeloid cells. Blood\| PubMed ID: 17596540	2007
Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A. Blood\| PubMed ID: 18272814	2008
Dll4 activation of Notch signaling reduces tumor vascularity and inhibits tumor growth. Blood\| PubMed ID: 18577711	2008
Palmitoylation controls recycling in lysosomal sorting and trafficking. Traffic (Copenhagen, Denmark)\| PubMed ID: 18817523	2008
Gene regulation and functional alterations induced by Kaposi's sarcoma-associated herpesvirus-encoded ORFK13/vFLIP in endothelial cells. Journal of virology\| PubMed ID: 19091861	2009
EphrinB reverse signaling contributes to endothelial and mural cell assembly into vascular structures. Blood\| PubMed ID: 19411631	2009
Targeting the mammalian target of Rapamycin to inhibit VEGF and cytokines for the treatment of primary effusion lymphoma. Leukemia\| PubMed ID: 19554030	2009
Regulation of angiogenesis in malignancies associated with Epstein-Barr virus and Kaposi's sarcoma-associated herpes virus. Future microbiology\| PubMed ID: 19722843	2009
The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis. Cancer cell\| PubMed ID: 19732724	2009
Impaired recruitment of Grk6 and beta-Arrestin 2 causes delayed internalization and desensitization of a WHIM syndrome-associated CXCR4 mutant receptor. PloS one\| PubMed ID: 19956569	2009
The transcription factor Gfi1 regulates G-CSF signaling and neutrophil development through the Ras activator RasGRP1. Blood\| PubMed ID: 20203268	2010
An interleukin-6-related systemic inflammatory syndrome in patients co-infected with Kaposi sarcoma-associated herpesvirus and HIV but without Multicentric Castleman disease. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 20583924	2010
Oligo-guanosine nucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis. Blood\| PubMed ID: 20606164	2010
NF-kappaB activation stimulates transcription and replication of retrovirus XMRV in human B-lineage and prostate carcinoma cells. Journal of virology\| PubMed ID: 21270144	2011
Adult human circulating CD34â»Linâ»CD45â»CD133â» cells can differentiate into hematopoietic and endothelial cells. Blood\| PubMed ID: 21715308	2011
Viral interleukin-6: role in Kaposi's sarcoma-associated herpesvirus: associated malignancies. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research\| PubMed ID: 21767154	2011
PEGylation potentiates the effectiveness of an antagonistic peptide that targets the EphB4 receptor with nanomolar affinity. PloS one\| PubMed ID: 22194865	2011
HHV-8-encoded viral IL-6 collaborates with mouse IL-6 in the development of multicentric Castleman disease in mice. Blood\| PubMed ID: 22490805	2012
Semaphorin 6A regulates angiogenesis by modulating VEGF signaling. Blood\| PubMed ID: 23007403	2012
Human herpesvirus 8+ polyclonal IgMλ B-cell lymphocytosis mimicking plasmablastic leukemia/lymphoma in HIV-infected patients. European journal of haematology\| PubMed ID: 23992152	2013
Attenuation of eph receptor kinase activation in cancer cells by coexpressed ephrin ligands. PloS one\| PubMed ID: 24348920	2013
Tumor-infiltrating myeloid cells activate Dll4/Notch/TGF-β signaling to drive malignant progression. Cancer research\| PubMed ID: 24520074	2014
Notch and TGFβ: Functional partners facilitating tumor progression. Oncoimmunology\| PubMed ID: 25114830	2014
Contribution of viral mimics of cellular genes to KSHV infection and disease. Viruses\| PubMed ID: 25243371	2014
GRANULOCYTE INFILTRATION AND EXPRESSION OF THE PRO-ANGIOGENIC BV8 PROTEIN IN EXPERIMENTAL EL4 AND LEWIS LUNG CARCINOMA TUMORS. Cureus\| PubMed ID: 25493215	2013
EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nature communications\| PubMed ID: 25807892	2015
Induction of Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral Interleukin-6 by X-Box Binding Protein 1. Journal of virology\| PubMed ID: 26491160	2016
Clinical Features and Outcomes of Patients With Symptomatic Kaposi Sarcoma Herpesvirus (KSHV)-associated Inflammation: Prospective Characterization of KSHV Inflammatory Cytokine Syndrome (KI... Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 26658701	2016
Identification of IL-23p19 as an endothelial proinflammatory peptide that promotes gp130-STAT3 signaling. Science signaling\| PubMed ID: 26980441	2016
EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta. Scientific reports\| PubMed ID: 27250641	2016
Burkitt lymphoma expresses oncofetal chondroitin sulfate without being a reservoir for placental malaria sequestration. International journal of cancer\| PubMed ID: 27997697	2017
Evidence for a Mesothelial Origin of Body Cavity Effusion Lymphomas. Journal of the National Cancer Institute\| PubMed ID: 28376153	2017
Ephrin ligands and Eph receptors contribution to hematopoiesis. Cellular and molecular life sciences : CMLS\| PubMed ID: 28589441	2017
Effects of DLC1 Deficiency on Endothelial Cell Contact Growth Inhibition and Angiosarcoma Progression. Journal of the National Cancer Institute\| PubMed ID: 29202196	2018
Novel insights into endothelial cell malignancies. Oncotarget\| PubMed ID: 30680062	2018
DLC1 deficiency and YAP signaling drive endothelial cell contact inhibition of growth and tumorigenesis. Oncogene\| PubMed ID: 31409902	2019
Identification of Eph receptor signaling as a regulator of autophagy and a therapeutic target in colorectal carcinoma. Molecular oncology\| PubMed ID: 31545551	2019
Vasculopathy and Coagulopathy Associated with SARS-CoV-2 Infection. Cells\| PubMed ID: 32629875	2020
Iterative epigenomic analyses in the same single cell. Genome research\| PubMed ID: 33627472	2021
Targeting the SHP2 phosphatase promotes vascular damage and inhibition of tumor growth. EMBO molecular medicine\| PubMed ID: 34102002	2021
Bone marrow niches in myelodysplastic syndromes. Journal of cancer metastasis and treatment\| PubMed ID: 34746416	2021