Florence Toti

Universite de Strasbourg

Affiliated withUniversite de Strasbourg INSERM (French National Institute of Health and Medical Research)University of Strasbourg

Research Area

Biology

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 4	2022
Publication title	2026

Other Publications

Article	Year
Bench-to-bedside review: circulating microparticles--a new player in sepsis? Critical care (London, England)\| PubMed ID: 21067540	2010
Cellular mechanisms underlying the formation of circulating microparticles. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21160064	2011
Microparticles: a critical component in the nexus between inflammation, immunity, and thrombosis. Seminars in immunopathology\| PubMed ID: 21866419	2011
Medium-chain triglyceride supplementation exacerbates peritonitis-induced septic shock in rats: role on cell membrane remodeling. Shock (Augusta, Ga.)\| PubMed ID: 25243422	2014
Lipid emulsions for parenteral nutrition in critical illness. Progress in lipid research\| PubMed ID: 26416578	2015
The Redox-sensitive Induction of the Local Angiotensin System Promotes Both Premature and Replicative Endothelial Senescence: Preventive Effect of a Standardized Crataegus Extract. The journals of gerontology. Series A, Biological sciences and medical sciences\| PubMed ID: 26672612	2016
Early Detection of Disseminated Intravascular Coagulation During Septic Shock: A Multicenter Prospective Study. Critical care medicine\| PubMed ID: 27322364	2016
Neutrophil Fluorescence: A New Indicator of Cell Activation During Septic Shock-Induced Disseminated Intravascular Coagulation. Critical care medicine\| PubMed ID: 27441905	2016
Endothelial Microparticles From Acute Coronary Syndrome Patients Induce Premature Coronary Artery Endothelial Cell Aging and Thrombogenicity: Role of the Ang II/AT1 Receptor/NADPH Oxidase-Me... Circulation\| PubMed ID: 27821539	2017
Lipid Emulsions Containing Medium Chain Triacylglycerols Blunt Bradykinin-Induced Endothelium-Dependent Relaxation in Porcine Coronary Artery Rings. Lipids\| PubMed ID: 28044232	2017
Replicative senescence promotes prothrombotic responses in endothelial cells: Role of NADPH oxidase- and cyclooxygenase-derived oxidative stress. Experimental gerontology\| PubMed ID: 28412252	2017
Thrombomodulin favors leukocyte microvesicle fibrinolytic activity, reduces NETosis and prevents septic shock-induced coagulopathy in rats. Annals of intensive care\| PubMed ID: 29222696	2017
Angiotensin II-induced redox-sensitive SGLT1 and 2 expression promotes high glucose-induced endothelial cell senescence. Journal of cellular and molecular medicine\| PubMed ID: 30929316	2020
DNA-bound elastase of neutrophil extracellular traps degrades plasminogen, reduces plasmin formation, and decreases fibrinolysis: proof of concept in septic shock plasma. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 31682515	2019
Ageing enhances the shedding of splenocyte microvesicles with endothelial pro-senescent effect that is prevented by a short-term intake of omega-3 PUFA EPA:DHA 6:1. Biochemical pharmacology\| PubMed ID: 31811867	2020
Atrial Fibrillation Progression Is Associated with Cell Senescence Burden as Determined by p53 and p16 Expression. Journal of clinical medicine\| PubMed ID: 31878008	2019
Porphyromonas gingivalis triggers the shedding of inflammatory endothelial microvesicles that act as autocrine effectors of endothelial dysfunction. Scientific reports\| PubMed ID: 32019950	2020
In Vitro Impact of Pro-Senescent Endothelial Microvesicles on Isolated Pancreatic Rat Islets Function. Transplantation proceedings\| PubMed ID: 33934912	2021
Long-term cardiovascular complications following sepsis: is senescence the missing link? Annals of intensive care\| PubMed ID: 34851467	2021
Exocrine cell-derived microparticles in response to lipopolysaccharide promote endocrine dysfunction in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society\| PubMed ID: 24095207	2014
Do atrial differences in endothelial damage, leukocyte and platelet activation, or tissue factor activity contribute to chamber-specific thrombogenic status in patients with atrial fibrillat... Journal of cardiovascular electrophysiology\| PubMed ID: 24172190	2014
Liraglutide protects Rin-m5f β cells by reducing procoagulant tissue factor activity and apoptosis prompted by microparticles under conditions mimicking Instant Blood-Mediated Inflammatory R... Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 24612163	2014
β cell membrane remodelling and procoagulant events occur in inflammation-driven insulin impairment: a GLP-1 receptor dependent and independent control. Journal of cellular and molecular medicine\| PubMed ID: 26607759	2016
Once versus twice daily injection of enoxaparin for thromboprophylaxis in bariatric surgery: effects on antifactor Xa activity and procoagulant microparticles. A randomized controlled study. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery\| PubMed ID: 26686309	2016
An Intravenous Bolus of Epa: Dha 6: 1 Protects Against Myocardial Ischemia-Reperfusion-Induced Shock. Shock (Augusta, Ga.)\| PubMed ID: 27058043	2016
Differential influence of tacrolimus and sirolimus on mitochondrial-dependent signaling for apoptosis in pancreatic cells. Molecular and cellular biochemistry\| PubMed ID: 27344165	2016
Microparticles: A new insight into lung primary graft dysfunction? Human immunology\| PubMed ID: 27381358	2016
Evidence of Netosis in Septic Shock-Induced Disseminated Intravascular Coagulation. Shock (Augusta, Ga.)\| PubMed ID: 27488091	2017
Senescence of Pancreas in Middle-Aged Rats with Normal Vascular Function. Annals of transplantation\| PubMed ID: 28360408	2017
Endothelial microparticles released by activated protein C protect beta cells through EPCR/PAR1 and annexin A1/FPR2 pathways in islets. Journal of cellular and molecular medicine\| PubMed ID: 28524456	2017
Thromboprophylaxis in the obese surgical patient. European journal of anaesthesiology\| PubMed ID: 30624292	2019
Assessment of plasma microvesicles to monitor pancreatic islet graft dysfunction: Beta cell- and leukocyte-derived microvesicles as specific features in a pilot longitudinal study. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 31319009	2020
Epithelial-mesenchymal transition and membrane microparticles: Potential implications for bronchiolitis obliterans syndrome after lung transplantation. Transplant immunology\| PubMed ID: 32097721	2020
Significance of neutrophil microparticles in ischaemia-reperfusion: Pro-inflammatory effectors of endothelial senescence and vascular dysfunction. Journal of cellular and molecular medicine\| PubMed ID: 32520423	2020
Angiotensin II-induced upregulation of SGLT1 and 2 contributes to human microparticle-stimulated endothelial senescence and dysfunction: protective effect of gliflozins. Cardiovascular diabetology\| PubMed ID: 33726768	2021
Septic shock as a trigger of arterial stress-induced premature senescence: A new pathway involved in the post sepsis long-term cardiovascular complications. Vascular pharmacology\| PubMed ID: 34592427	2021
Mesenchymal stem cell-derived exosomes as cell free nanotherapeutics and nanocarriers. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 38914247	2024
Human Aortic Stenotic Valve-Derived Extracellular Vesicles Induce Endothelial Dysfunction and Thrombogenicity Through AT1R/NADPH Oxidases/SGLT2 Pro-Oxidant Pathway. JACC. Basic to translational science\| PubMed ID: 39170957	2024
Tranexamic acid impairs plasmin generation on human mesenchymal stem cells and derived membrane microvesicles, halting pericellular proteolysis. Frontiers in medicine\| PubMed ID: 40662070	2025
Serum CD73 activity as a biomarker of hypoxemia in COVID-19 patients. Scientific reports\| PubMed ID: 41748828	2026
Emerging role of nucleic acid aptamers in sepsis-induced coagulopathy: Future perspectives in diagnostics and therapeutics. Annals of intensive care\| PubMed ID: 41788474	2026