Jack Gorski

Laboratory of Molecular Genetics, Blood Research Institute

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 8	2012

Other Publications

Article	Year
C-terminal anchoring of a peptide to class II MHC via the P10 residue is compatible with a peptide bulge. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 11801666	2002
Overlap of direct and indirect alloreactive T-cell repertoires when MHC polymorphism is limited to the peptide binding groove. Human immunology\| PubMed ID: 11821156	2002
A molecular marker for thymocyte-positive selection: selection of CD4 single-positive thymocytes with shorter TCRB CDR3 during T cell development. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 11937532	2002
Re-establishing peripheral tolerance in the absence of CTLA-4: complementation by wild-type T cells points to an indirect role for CTLA-4. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12165509	2002
Evidence for preferred MHC class II-TCR recognition independent of the source of bound peptide. European journal of immunology\| PubMed ID: 12209630	2002
Elimination of leukemia in the absence of lethal graft-versus-host disease after allogenic bone marrow transplantation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12626559	2003
A fractal clonotype distribution in the CD8+ memory T cell repertoire could optimize potential for immune responses. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12682227	2003
T cell receptor CDR3 loop length repertoire is determined primarily by features of the V(D)J recombination reaction. European journal of immunology\| PubMed ID: 12778474	2003
Cutting edge: TCR contacts as anchors: effects on affinity and HLA-DM stability. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14634075	2003
Selective elimination of alloreactive donor T cells attenuates graft-versus-host disease and enhances T-cell reconstitution. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 14677113	2003
Gamma delta T cell regulation of IFN-gamma production by central nervous system-infiltrating encephalitogenic T cells: correlation with recovery from experimental autoimmune encephalomyeliti... Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15265886	2004
A polymorphic pocket at the P10 position contributes to peptide binding specificity in class II MHC proteins. Chemistry & biology\| PubMed ID: 15489166	2004
Cooperativity during the formation of peptide/MHC class II complexes. Biochemistry\| PubMed ID: 15823020	2005
Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies. The Journal of clinical investigation\| PubMed ID: 16823491	2006
Complex T cell memory repertoires participate in recall responses at extremes of antigenic load. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16849515	2006
Homeostatic expansion and repertoire regeneration of donor T cells during graft versus host disease is constrained by the host environment. Blood\| PubMed ID: 17347406	2007
Cooperativity of hydrophobic anchor interactions: evidence for epitope selection by MHC class II as a folding process. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17513767	2007
Crystallographic structure of the human leukocyte antigen DRA, DRB3*0101: models of a directional alloimmune response and autoimmunity. Journal of molecular biology\| PubMed ID: 17583734	2007
Quantitative measurement of pathogen-specific human memory T cell repertoire diversity using a CDR3 beta-specific microarray. BMC genomics\| PubMed ID: 17880719	2007
Long-term results of bone marrow transplantation in complete DiGeorge syndrome. The Journal of allergy and clinical immunology\| PubMed ID: 17931564	2007
Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5. Blood\| PubMed ID: 18796632	2008
HLA-DM mediates epitope selection by a "compare-exchange" mechanism when a potential peptide pool is available. PloS one\| PubMed ID: 19005572	2008
An accessible micro-capillary electrophoresis device using surface-tension-driven flow. Electrophoresis\| PubMed ID: 19425002	2009
A clonotype nomenclature for T cell receptors. Immunogenetics\| PubMed ID: 19568742	2009
The transcription factor RFX protects MHC class II genes against epigenetic silencing by DNA methylation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19620312	2009
Two compensatory pathways maintain long-term stability and diversity in CD8 T cell memory repertoires. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19635925	2009
Peptide-MHC class II complex stability governs CD4 T cell clonal selection. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20007533	2010
Cutting edge: HLA-DM-mediated peptide exchange functions normally on MHC class II-peptide complexes that have been weakened by elimination of a conserved hydrogen bond. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20038641	2010
Phospholipase C{gamma}1 is essential for T cell development, activation, and tolerance. The Journal of experimental medicine\| PubMed ID: 20123962	2010
Simulation studies for a multistage dynamic process of immune memory response to influenza: experiment in silico. Annales zoologici Fennici\| PubMed ID: 20717502	2008
Disproportional effects in populations of concern for pandemic influenza: insights from seasonal epidemics in Wisconsin, 1967-2004. Influenza and other respiratory viruses\| PubMed ID: 20836795	2010
Functional dichotomy between NKG2D and CD28-mediated co-stimulation in human CD8+ T cells. PloS one\| PubMed ID: 20844584	2010
Naive T cell repertoire skewing in HLA-A2 individuals by a specialized rearrangement mechanism results in public memory clonotypes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21282510	2011
Selective T cell expansion during aging of CD8 memory repertoires to influenza revealed by modeling. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21515795	2011
The polyclonal CD8 T cell response to influenza M158-66 generates a fully connected network of cross-reactive clonotypes to structurally related peptides: a paradigm for memory repertoire co... Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21518969	2011
A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity. Immunity\| PubMed ID: 21723159	2011