Nicola L. Jones

Cell Biology, Hospital for Sick Children

Affiliated withHospital for Sick Children University of Toronto

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2022

Other Publications

Article	Year
Helicobacter pylori induces gastric epithelial cell apoptosis in association with increased Fas receptor expression. Infection and immunity\| PubMed ID: 10417197	1999
Enhanced disease severity in Helicobacter pylori-infected mice deficient in Fas signaling. Infection and immunity\| PubMed ID: 11953400	2002
Escherichia coli shiga-like toxins induce apoptosis and cleavage of poly(ADP-ribose) polymerase via in vitro activation of caspases. Infection and immunity\| PubMed ID: 12117981	2002
Detection of Shiga toxin-mediated programmed cell death and delineation of death-signaling pathways. Methods in molecular medicine\| PubMed ID: 12375433	2003
Helicobacter pylori strains expressing the vacuolating cytotoxin interrupt phagosome maturation in macrophages by recruiting and retaining TACO (coronin 1) protein. Cellular microbiology\| PubMed ID: 12542468	2003
Helicobacter pylori infection interferes with epithelial Stat6-mediated interleukin-4 signal transduction independent of cagA, cagE, or VacA. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12902508	2003
Fascination with bacteria-triggered cell death: the significance of Fas-mediated apoptosis during bacterial infection in vivo. Microbes and infection\| PubMed ID: 14554257	2003
Helicobacter pylori disrupts STAT1-mediated gamma interferon-induced signal transduction in epithelial cells. Infection and immunity\| PubMed ID: 14688135	2004
Helicobacter pylori induces apoptosis of macrophages in association with alterations in the mitochondrial pathway. Infection and immunity\| PubMed ID: 15102801	2004
Probiotics reduce bacterial colonization and gastric inflammation in H. pylori-infected mice. Digestive diseases and sciences\| PubMed ID: 15387328	2004
Helicobacter pylori infection and gastric cancer: host, bug, environment, or all three? Current gastroenterology reports\| PubMed ID: 15527671	2004
Amelioration of the effects of Citrobacter rodentium infection in mice by pretreatment with probiotics. The Journal of infectious diseases\| PubMed ID: 15897997	2005
Canadian Helicobacter Study Group Consensus Conference: Update on the approach to Helicobacter pylori infection in children and adolescents--an evidence-based evaluation. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 16010300	2005
Pediatric gastrointestinal diseases: are drugs the answer? Current opinion in pharmacology\| PubMed ID: 16199203	2005
Oral vaccination against Helicobacter pylori infection is not effective in mice with Fas ligand deficiency. Digestive diseases and sciences\| PubMed ID: 16416178	2005
Autophagy: healthy eating and self-digestion for gastroenterologists. Journal of pediatric gastroenterology and nutrition\| PubMed ID: 18493203	2008
Helicobacter pylori cytotoxin-associated gene A activates the signal transducer and activator of transcription 3 pathway in vitro and in vivo. Cancer research\| PubMed ID: 19147578	2009
Effect of Helicobacter pylori's vacuolating cytotoxin on the autophagy pathway in gastric epithelial cells. Autophagy\| PubMed ID: 19164948	2009
Autophagy as an emerging dimension to adaptive and innate immunity. Seminars in immunology\| PubMed ID: 19502083	2009
A review of current guidelines for the management of Helicobacter pylori infection in children and adolescents. Paediatrics & child health\| PubMed ID: 19688080	2004
Methods to monitor autophagy in H. pylori vacuolating cytotoxin A (VacA)-treated cells. Autophagy\| PubMed ID: 19875940	2010
Detergent-resistant microdomains mediate activation of host cell signaling in response to attaching-effacing bacteria. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 19997063	2010
Helicobacter pylori activates calpain via toll-like receptor 2 to disrupt adherens junctions in human gastric epithelial cells. Infection and immunity\| PubMed ID: 21825064	2011
Helicobacter pylori treatment in the hospital setting: a potential model for developing quality improvement initiatives to prevent missed test results. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 22059157	2011
Autophagy: a primer for the gastroenterologist/hepatologist. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 22175057	2011
Helicobacter pylori and immigrant health. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne\| PubMed ID: 22232338	2012
Helicobacter pylori in First Nations and recent immigrant populations in Canada. Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 22312609	2012
Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans. Gastroenterology\| PubMed ID: 22333951	2012
Crohn disease ATG16L1 polymorphism increases susceptibility to infection with Helicobacter pylori in humans. Autophagy\| PubMed ID: 22885761	2012
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy\| PubMed ID: 22966490	2012
Cell culture-based assays to test for bacterial adherence and internalization. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23015493	2012
Cell culture assays to evaluate bacterial toxicity and virulence. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23015494	2012
Modulation of autophagy by Helicobacter pylori and its role in gastric carcinogenesis. Trends in microbiology\| PubMed ID: 24156875	2013
What is the best regimen for Helicobacter pylori eradication in Canadian Arctic Aboriginals? Canadian journal of gastroenterology = Journal canadien de gastroenterologie\| PubMed ID: 24340311	2013
Helicobacter pylori inhibits dendritic cell maturation via interleukin-10-mediated activation of the signal transducer and activator of transcription 3 pathway. Journal of innate immunity\| PubMed ID: 25412627	2015
Microbial Disruption of Autophagy Alters Expression of the RISC Component AGO2, a Critical Regulator of the miRNA Silencing Pathway. Inflammatory bowel diseases\| PubMed ID: 26332312	2015
The Toronto Consensus for the Treatment of Helicobacter pylori Infection in Adults. Gastroenterology\| PubMed ID: 27102658	2016
Protein kinase C δ signaling is required for dietary prebiotic-induced strengthening of intestinal epithelial barrier function. Scientific reports\| PubMed ID: 28098206	2017
VacA promotes CagA accumulation in gastric epithelial cells during Helicobacter pylori infection. Scientific reports\| PubMed ID: 30631092	2019
VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1. Nature microbiology\| PubMed ID: 31110360	2019
MCOLN1/TRPML1 inhibition - a novel strategy used by to escape autophagic killing and antibiotic eradication therapy . Autophagy\| PubMed ID: 31599196	2020
2019 Harry Shwachman Award: Dr Anne M. Griffiths, MD, FRCPC. Journal of pediatric gastroenterology and nutrition\| PubMed ID: 31880672	2020
Development of the patient-oriented research curriculum in child health (PORCCH). Research involvement and engagement\| PubMed ID: 33971980	2021
Helicobacter pylori Infection. Gastroenterology clinics of North America\| PubMed ID: 34024441	2021
Vitamin D deficiency enhances expression of autophagy-regulating miR-142-3p in mouse and "involved" IBD patient intestinal tissues. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 34159811	2021
Under the Radar: Strategies Used by to Evade Host Responses. Annual review of physiology\| PubMed ID: 34672717	2022
High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in iPSC-Derived Human Intestinal Organoids. Cells\| PubMed ID: 34943927	2021