Robert Langer

Robert Langer

David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology

Affiliated withMassachusetts Institute of Technology

Research Area

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JoVE Journal Publications

ArticleTotal : 2
Year
Polymer Microarrays for High Throughput Discovery of Biomaterials
Publication title

Cited by 33

2012
2013

Other Publications

Article
Year
The evolution of biomaterials. Interview by Alison Stoddart and Victoria Cleave.

Nature materials| PubMed ID: 19458638

2009
Nanoparticle delivery of suicide DNA for epithelial ovarian cancer therapy.

Advances in experimental medicine and biology| PubMed ID: 18546630

2008
2012
Nanotechnology and aptamers: applications in drug delivery.

Trends in biotechnology| PubMed ID: 18571753

2008
Triggered release of siRNA from poly(ethylene glycol)-protected, pH-dependent liposomes.

Journal of controlled release : official journal of the Controlled Release Society| PubMed ID: 18601962

2008
2008
2008
nan'o.tech.nol'o.gy n.

Nature nanotechnology| PubMed ID: 18654128

2006
Nanocarriers as an emerging platform for cancer therapy.

Nature nanotechnology| PubMed ID: 18654426

2007
2008
The biocompatibility of mesoporous silicates.

Biomaterials| PubMed ID: 18675454

2008
2008
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 18695239

2008
2008
2008
A review of Judah Folkman's remarkable achievements in biomedicine.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 18772371

2008
Assessing siRNA pharmacodynamics in a luciferase-expressing mouse.

Molecular therapy : the journal of the American Society of Gene Therapy| PubMed ID: 18781145

2008
2008
2008
Biodegradable poly(polyol sebacate) polymers.

Biomaterials| PubMed ID: 18824260

2008
Cell-compatible, multicomponent protein arrays with subcellular feature resolution.

Small (Weinheim an der Bergstrasse, Germany)| PubMed ID: 18844310

2008
2009
Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 18978032

2008
2008
Three-dimensional conductive constructs for nerve regeneration.

Journal of biomedical materials research. Part A| PubMed ID: 18985787

2009
Transdermal drug delivery.

Nature biotechnology| PubMed ID: 18997767

2008
Developing a distributed research network to conduct population-based studies and safety surveillance.

AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium| PubMed ID: 18999251

2008
2008
Outbreak of adverse reactions associated with contaminated heparin.

The New England journal of medicine| PubMed ID: 19052120

2008
Poly(beta-amino esters): procedures for synthesis and gene delivery.

Methods in molecular biology (Clifton, N.J.)| PubMed ID: 19085119

2009
In vitro and in vivo degradation of poly(1,3-diamino-2-hydroxypropane-co-polyol sebacate) elastomers.

Journal of biomedical materials research. Part A| PubMed ID: 19107786

2009
2009
A drug-eluting contact lens.

Investigative ophthalmology & visual science| PubMed ID: 19136709

2009
2009
Knocking down barriers: advances in siRNA delivery.

Nature reviews. Drug discovery| PubMed ID: 19180106

2009
Incident invasive breast cancer, geographic location of residence, and reported average time spent outside.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology| PubMed ID: 19190147

2009
2011
Multifunctional nanoparticles for prostate cancer therapy.

Expert review of anticancer therapy| PubMed ID: 19192959

2009
Protein nanoparticles engineered to sense kinase activity in MRI.

Journal of the American Chemical Society| PubMed ID: 19199639

2009
Impact of nanotechnology on drug delivery.

ACS nano| PubMed ID: 19206243

2009
2008
2009
Claudin-3 gene silencing with siRNA suppresses ovarian tumor growth and metastasis.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 19208807

2009
Rheological blends for drug delivery. I. Characterization in vitro.

Journal of biomedical materials research. Part A| PubMed ID: 19235215

2010
Development of lipidoid-siRNA formulations for systemic delivery to the liver.

Molecular therapy : the journal of the American Society of Gene Therapy| PubMed ID: 19259063

2009
2009
2009
2009
2009
2009
Prolonged duration local anesthesia with minimal toxicity.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 19365067

2009
2009
2009
2009
Progress in tissue engineering.

Scientific American| PubMed ID: 19438051

2009
Implantable diagnostic device for cancer monitoring.

Biosensors & bioelectronics| PubMed ID: 19442510

2009
Arpad Gerster and Max Thorek contributions to American surgery.

Journal of investigative surgery : the official journal of the Academy of Surgical Research| PubMed ID: 19466652

2009
2009
Formulation/preparation of functionalized nanoparticles for in vivo targeted drug delivery.

Methods in molecular biology (Clifton, N.J.)| PubMed ID: 19488725

2009
Engineering substrate topography at the micro- and nanoscale to control cell function.

Angewandte Chemie (International ed. in English)| PubMed ID: 19492373

2009
2009
2009
2009
High-throughput membrane surface modification to control NOM fouling.

Environmental science & technology| PubMed ID: 19544900

2009
Drug delivery-mediated control of RNA immunostimulation.

Molecular therapy : the journal of the American Society of Gene Therapy| PubMed ID: 19584813

2009
High throughput optimization of stem cell microenvironments.

Combinatorial chemistry & high throughput screening| PubMed ID: 19601753

2009
2009
2010
Efficacy, safety, and tolerability of low-dose hormone therapy in managing menopausal symptoms.

Journal of the American Board of Family Medicine : JABFM| PubMed ID: 19734403

2009
2009
2009
Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 19805054

2010
Orthogonal analytical approaches to detect potential contaminants in heparin.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 19805108

2009
2009
2010
2010
Photo-targeted nanoparticles.

Nano letters| PubMed ID: 19904979

2010
Vascular differentiation of human embryonic stem cells in bioactive hydrogel-based scaffolds.

Methods in molecular biology (Clifton, N.J.)| PubMed ID: 19907986

2010
2010
2010
2010
The Cardiovascular Research Network: a new paradigm for cardiovascular quality and outcomes research.

Circulation. Cardiovascular quality and outcomes| PubMed ID: 20031802

2008
2009
Bioinspired materials for controlling stem cell fate.

Accounts of chemical research| PubMed ID: 20043634

2010
Lipid-like materials for low-dose, in vivo gene silencing.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 20080679

2010
2010
Spatiotemporal controlled delivery of nanoparticles to injured vasculature.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 20133865

2010
2010
Emerging nanotechnology approaches for HIV/AIDS treatment and prevention.

Nanomedicine (London, England)| PubMed ID: 20148638

2010
Impaired metabolism in donor kidney grafts after steroid pretreatment.

Transplant international : official journal of the European Society for Organ Transplantation| PubMed ID: 20149158

2010
Injectable hyaluronic acid-dextran hydrogels and effects of implantation in ferret vocal fold.

Journal of biomedical materials research. Part B, Applied biomaterials| PubMed ID: 20151459

2010
2010
2010
Nanoparticle technologies for cancer therapy.

Handbook of experimental pharmacology| PubMed ID: 20217526

2010
Polymeric nanoparticles for drug delivery.

Methods in molecular biology (Clifton, N.J.)| PubMed ID: 20217595

2010
2010
2010
2010
Optimizing the delivery of cancer drugs that block angiogenesis.

Science translational medicine| PubMed ID: 20371469

2010
2010
Progress in siRNA delivery using multifunctional nanoparticles.

Methods in molecular biology (Clifton, N.J.)| PubMed ID: 20387142

2010
2010
Estrogen alone in postmenopausal women and breast cancer detection by means of mammography and breast biopsy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology| PubMed ID: 20439627

2010
2010
2010
Biodegradable xylitol-based elastomers: in vivo behavior and biocompatibility.

Journal of biomedical materials research. Part A| PubMed ID: 20540093

2010
2010
2010
2010
2010
2011
2010
2010
2010
Poly(ethylene glycol) with observable shedding.

Angewandte Chemie (International ed. in English)| PubMed ID: 20677297

2010
2010
2010
2010
2010
2010
2010
2011
2010
Molecular biomarker candidates of acute kidney injury in zero-hour renal transplant needle biopsies.

Transplant international : official journal of the European Society for Organ Transplantation| PubMed ID: 20819195

2011
2010
2010
2011
2011
Perspectives and challenges in tissue engineering and regenerative medicine.

Advanced materials (Deerfield Beach, Fla.)| PubMed ID: 20882493

2009
Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 20921363

2010
2010
2010
2010
2011
2011
2011
2010
On firm ground: IP protection of therapeutic nanoparticles.

Nature biotechnology| PubMed ID: 21139609

2010
2011
Nanotechnological strategies for engineering complex tissues.

Nature nanotechnology| PubMed ID: 21151110

2011
Efficient Hydrogenation of Ketones Catalyzed by an Iron Pincer Complex.

Angewandte Chemie (International ed. in English)| PubMed ID: 21210406

2011
2011
2010
2011
Ultrasound-mediated transdermal drug delivery: mechanisms, scope, and emerging trends.

Journal of controlled release : official journal of the Controlled Release Society| PubMed ID: 21238514

2011
2011
A "Self-Pinning" Adhesive Based on Responsive Surface Wrinkles.

Journal of polymer science. Part B, Polymer physics| PubMed ID: 21293787

2011
2011
Application of a dense gas technique for sterilizing soft biomaterials.

Biotechnology and bioengineering| PubMed ID: 21337339

2011
Efficient hydrogenation of ketones catalyzed by an iron pincer complex.

Angewandte Chemie (International ed. in English)| PubMed ID: 21344565

2011
2011
Indirect low-intensity ultrasonic stimulation for tissue engineering.

Journal of tissue engineering| PubMed ID: 21350648

2010
Current trends in nanobiosensor technology.

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology| PubMed ID: 21391305

2011
A novel family of biodegradable poly(ester amide) elastomers.

Advanced materials (Deerfield Beach, Fla.)| PubMed ID: 21394790

2011
2011
2011
Responsive microgrooves for the formation of harvestable tissue constructs.

Langmuir : the ACS journal of surfaces and colloids| PubMed ID: 21449596

2011
2011
2011
2011
2011
2011
2011
2011
Five years of siRNA delivery: spotlight on gold nanoparticles.

Small (Weinheim an der Bergstrasse, Germany)| PubMed ID: 21681985

2011
Poly(β-amino ester)-DNA complexes: time-resolved fluorescence and cellular transfection studies.

Journal of controlled release : official journal of the Controlled Release Society| PubMed ID: 21699928

2011
Synergistic silencing: combinations of lipid-like materials for efficacious siRNA delivery.

Molecular therapy : the journal of the American Society of Gene Therapy| PubMed ID: 21750531

2011
2011
Serum selenium, genetic variation in selenoenzymes, and risk of colorectal cancer: primary analysis from the Women's Health Initiative Observational Study and meta-analysis.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology| PubMed ID: 21765007

2011
Responsive micromolds for sequential patterning of hydrogel microstructures.

Journal of the American Chemical Society| PubMed ID: 21766872

2011
Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 21784981

2011
Research agenda. Promoting convergence in biomedical science.

Science (New York, N.Y.)| PubMed ID: 21798916

2011
Microgels for efficient protein purification.

Advanced materials (Deerfield Beach, Fla.)| PubMed ID: 21805505

2011
2011
Hydroxyapatite for keratoprosthesis biointegration.

Investigative ophthalmology & visual science| PubMed ID: 21849419

2011
Liposomes for HIV prophylaxis.

Biomaterials| PubMed ID: 21862123

2011
2011
2011
Nanoparticle delivery of cancer drugs.

Annual review of medicine| PubMed ID: 21888516

2012
Nanoparticles targeting the infarcted heart.

Nano letters| PubMed ID: 21899318

2011
2012
2011
Nanowired three-dimensional cardiac patches.

Nature nanotechnology| PubMed ID: 21946708

2011
2011
2011
2011
2011
Fluorescent penetration enhancers for transdermal applications.

Journal of controlled release : official journal of the Controlled Release Society| PubMed ID: 22062691

2011
Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 22065768

2011
In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid-polymeric nanoparticles.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 22087004

2011
2011
Roma ethnicity and clinical outcomes in kidney transplant recipients.

International urology and nephrology| PubMed ID: 22116678

2011
Combinatorial library of lipidoids for in vitro DNA delivery.

Bioconjugate chemistry| PubMed ID: 22148515

2012
Forty-year journey of angiogenesis translational research.

Science translational medicine| PubMed ID: 22190240

2011
Treating metastatic cancer with nanotechnology.

Nature reviews. Cancer| PubMed ID: 22193407

2012
2012
2012
Progress in the Tissue Engineering and Stem Cell Industry "Are we there yet?"

Tissue engineering. Part B, Reviews| PubMed ID: 22220809

2012
Superstructure based on β-CD self-assembly induced by a small guest molecule.

Physical chemistry chemical physics : PCCP| PubMed ID: 22234498

2012
2012
2012
2012
First-in-human testing of a wirelessly controlled drug delivery microchip.

Science translational medicine| PubMed ID: 22344516

2012
2012
Photoswitchable nanoparticles for triggered tissue penetration and drug delivery.

Journal of the American Chemical Society| PubMed ID: 22385538

2012
Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 22421433

2012
2012
Therapeutic angiogenesis using genetically engineered human endothelial cells.

Journal of controlled release : official journal of the Controlled Release Society| PubMed ID: 22450331

2012
Reservoir-based drug delivery systems utilizing microtechnology.

Advanced drug delivery reviews| PubMed ID: 22465783

2012
Everolimus plus early tacrolimus minimization: a phase III, randomized, open-label, multicentre trial in renal transplantation.

Transplant international : official journal of the European Society for Organ Transplantation| PubMed ID: 22471345

2012
2012
2012
2012
2012
2012
2012
Melanin-like hydrogels derived from gallic macromers.

Advanced materials (Deerfield Beach, Fla.)| PubMed ID: 22566290

2012
2012
2012
2011
2012
2012
Laparoscopic donor nephrectomy techniques.

Current opinion in organ transplantation| PubMed ID: 22710384

2012
2012
A 3D interconnected microchannel network formed in gelatin by sacrificial shellac microfibers.

Advanced materials (Deerfield Beach, Fla.)| PubMed ID: 22826135

2012
2012
2012
2012
Do no harm: not even to some degree.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine| PubMed ID: 22893763

2012
2012
2012
Nanocomposite gold-silk nanofibers.

Nano letters| PubMed ID: 22928701

2012
Rapid skin permeabilization by the simultaneous application of dual-frequency, high-intensity ultrasound.

Journal of controlled release : official journal of the Controlled Release Society| PubMed ID: 22940128

2012
Detection and management of renal cell carcinoma in the renal allograft.

International urology and nephrology| PubMed ID: 22941752

2013
Controlling spatial organization of multiple cell types in defined 3D geometries.

Advanced materials (Deerfield Beach, Fla.)| PubMed ID: 22941804

2012
Crosslinked linear polyethylenimine enhances delivery of DNA to the cytoplasm.

Journal of controlled release : official journal of the Controlled Release Society| PubMed ID: 22995755

2013
Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles.

Integrative biology : quantitative biosciences from nano to macro| PubMed ID: 23014672

2013
2012
2012
Prolonged nerve blockade delays the onset of neuropathic pain.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23045676

2012
2013
Thermoresponsive Platforms for Tissue Engineering and Regenerative Medicine.

AIChE journal. American Institute of Chemical Engineers| PubMed ID: 23105146

2011
Quick-release medical tape.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23112196

2012
2012
2013
2012
Materials for diabetes therapeutics.

Advanced healthcare materials| PubMed ID: 23184741

2012
2013
2013
Microstructured barbs on the North American porcupine quill enable easy tissue penetration and difficult removal.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23236138

2012
Painting blood vessels and atherosclerotic plaques with an adhesive drug depot.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23236189

2012
A highly tunable biocompatible and multifunctional biodegradable elastomer.

Advanced materials (Deerfield Beach, Fla.)| PubMed ID: 23239051

2013
Modular 'click-in-emulsion' bone-targeted nanogels.

Advanced materials (Deerfield Beach, Fla.)| PubMed ID: 23280931

2013
2013
2013
A vector-free microfluidic platform for intracellular delivery.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23341631

2013
2012
2013
2013
2013
BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23447565

2013
Strategies for MCR image analysis of large hyperspectral data-sets.

Surface and interface analysis : SIA| PubMed ID: 23450109

2013
2013
2013
Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23533277

2013
One-Step Multipurpose Surface Functionalization by Adhesive Catecholamine.

Advanced functional materials| PubMed ID: 23580891

2012
2013
2013
2013
A Stiff Injectable Biodegradable Elastomer.

Advanced functional materials| PubMed ID: 23667350

2013
2013
2013
2013
2013
2013
2013
2013
2013
2013
Formation of an iron phosphine-borane complex by formal insertion of BH₃ into the Fe-P bond.

Dalton transactions (Cambridge, England : 2003)| PubMed ID: 23811820

2013
2013
Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23882076

2013
2013
2013
2013
2013
2013
2013
2013
2013
2013
2013
2012
2013
Electrical stimulation via a biocompatible conductive polymer directs retinal progenitor cell differentiation.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference| PubMed ID: 24110015

2013
Translating materials design to the clinic.

Nature materials| PubMed ID: 24150414

2013
Stretchable Polymeric Multielectrode Array for Conformal Neural Interfacing.

Advanced materials (Deerfield Beach, Fla.)| PubMed ID: 24150828

2013
Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 24167294

2013
High-throughput methods for screening polymeric transfection reagents.

Cold Spring Harbor protocols| PubMed ID: 24184768

2013