Daniel G. Anderson

David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology

Affiliated withMassachusetts Institute of Technology

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 33	2012

Other Publications

Article	Year
Parallel synthesis and biophysical characterization of a degradable polymer library for gene delivery. Journal of the American Chemical Society\| PubMed ID: 12720443	2003
Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery. Angewandte Chemie (International ed. in English)\| PubMed ID: 12866105	2003
Synthesis of poly(beta-amino ester)s optimized for highly effective gene delivery. Bioconjugate chemistry\| PubMed ID: 13129402	2003
Degradable poly(amino alcohol esters) as potential DNA vectors with low cytotoxicity. Biomacromolecules\| PubMed ID: 14606906	2003
pH-triggered release of macromolecules from spray-dried polymethacrylate microparticles. Pharmaceutical research\| PubMed ID: 14620503	2003
Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells. Nature biotechnology\| PubMed ID: 15195101	2004
Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15210954	2004
pH-triggered microparticles for peptide vaccination. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15294974	2004
Materials science. Smart biomaterials. Science (New York, N.Y.)\| PubMed ID: 15448260	2004
A polymer library approach to suicide gene therapy for cancer. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15520369	2004
Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters). Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 15727939	2005
Biomaterial microarrays: rapid, microscale screening of polymer-cell interaction. Biomaterials\| PubMed ID: 15763269	2005
Beta-amino ester polymers facilitate in vivo DNA transfection and adjuvant plasmid DNA immunization. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 15963932	2005
Direct patterning of mammalian cells onto porous tissue engineering substrates using agarose stamps. Biomaterials\| PubMed ID: 15979701	2005
Biodegradable polymeric vectors for gene delivery to human endothelial cells. Bioconjugate chemistry\| PubMed ID: 16984124	2006
Synthesis of poly(beta-amino ester)s with thiol-reactive side chains for DNA delivery. Journal of the American Chemical Society\| PubMed ID: 17002366	2006
Electrostatic ligand coatings of nanoparticles enable ligand-specific gene delivery to human primary cells. Nano letters\| PubMed ID: 17362046	2007
Rapid optimization of gene delivery by parallel end-modification of poly(beta-amino ester)s. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 17375071	2007
Nanoparticulate delivery of suicide DNA to murine prostate and prostate tumors. The Prostate\| PubMed ID: 17427200	2007
Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway. Nature\| PubMed ID: 17898712	2007
Gene delivery properties of end-modified poly(beta-amino ester)s. Bioconjugate chemistry\| PubMed ID: 17929884	2007
TOF-SIMS analysis of a 576 micropatterned copolymer array to reveal surface moieties that control wettability. Analytical chemistry\| PubMed ID: 18044847	2008
Nanomechanical control of cell rolling in two dimensions through surface patterning of receptors. Nano letters\| PubMed ID: 18321075	2008
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics. Nature biotechnology\| PubMed ID: 18438401	2008
Heme oxygenase-1 is an anti-inflammatory host factor that promotes murine plasmodium liver infection. Cell host & microbe\| PubMed ID: 18474360	2008
A Combinatorial Polymer Library Approach Yields Insight into Nonviral Gene Delivery. Accounts of chemical research\| PubMed ID: 18507402	2008
Nanoparticle delivery of suicide DNA for epithelial ovarian cancer therapy. Advances in experimental medicine and biology\| PubMed ID: 18546630	2008
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18695239	2008
Nanoparticles for gene transfer to human embryonic stem cell colonies. Nano letters\| PubMed ID: 18754690	2008
Delivery of small interfering RNA for inhibition of endothelial cell apoptosis by hypoxia and serum deprivation. Biochemical and biophysical research communications\| PubMed ID: 18765230	2008
Assessing siRNA pharmacodynamics in a luciferase-expressing mouse. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 18781145	2008
Cell-compatible, multicomponent protein arrays with subcellular feature resolution. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 18844310	2008
Nanoparticulate delivery of diphtheria toxin DNA effectively kills Mesothelin expressing pancreatic cancer cells. Cancer biology & therapy\| PubMed ID: 19039293	2008
Poly(beta-amino esters): procedures for synthesis and gene delivery. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19085119	2009
Knocking down barriers: advances in siRNA delivery. Nature reviews. Drug discovery\| PubMed ID: 19180106	2009
Claudin-3 gene silencing with siRNA suppresses ovarian tumor growth and metastasis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19208807	2009
Development of lipidoid-siRNA formulations for systemic delivery to the liver. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 19259063	2009
Preparation of monodisperse biodegradable polymer microparticles using a microfluidic flow-focusing device for controlled drug delivery. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 19296563	2009
A novel high-throughput cell-based method for integrated quantification of type I interferons and in vitro screening of immunostimulatory RNA drug delivery. Biotechnology and bioengineering\| PubMed ID: 19338049	2009
Gold, poly(beta-amino ester) nanoparticles for small interfering RNA delivery. Nano letters\| PubMed ID: 19422265	2009
Locally delivered growth factor enhances the angiogenic efficacy of adipose-derived stromal cells transplanted to ischemic limbs. Stem cells (Dayton, Ohio)\| PubMed ID: 19544425	2009
High-throughput membrane surface modification to control NOM fouling. Environmental science & technology\| PubMed ID: 19544900	2009
Drug delivery-mediated control of RNA immunostimulation. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 19584813	2009
Minicells overcome tumor drug-resistance. Nature biotechnology\| PubMed ID: 19587665	2009
High throughput optimization of stem cell microenvironments. Combinatorial chemistry & high throughput screening\| PubMed ID: 19601753	2009
Nanoparticle-delivered suicide gene therapy effectively reduces ovarian tumor burden in mice. Cancer research\| PubMed ID: 19643734	2009
Microfabrication of homogenous, asymmetric cell-laden hydrogel capsules. Biomaterials\| PubMed ID: 19800116	2009
Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19805054	2010
Nanoparticle-delivered multimeric soluble CD40L DNA combined with Toll-Like Receptor agonists as a treatment for melanoma. PloS one\| PubMed ID: 19812695	2009
High throughput methods applied in biomaterial development and discovery. Biomaterials\| PubMed ID: 19815273	2010
Tissue-specific gene delivery via nanoparticle coating. Biomaterials\| PubMed ID: 19850333	2010
Lipid-like materials for low-dose, in vivo gene silencing. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20080679	2010
Nanoparticulate cellular patches for cell-mediated tumoritropic delivery. ACS nano\| PubMed ID: 20121215	2010
Electrostatic surface modifications to improve gene delivery. Expert opinion on drug delivery\| PubMed ID: 20201712	2010
Rapid biocompatibility analysis of materials via in vivo fluorescence imaging of mouse models. PloS one\| PubMed ID: 20386609	2010
Combinatorial extracellular matrices for human embryonic stem cell differentiation in 3D. Biomacromolecules\| PubMed ID: 20614932	2010
Combinatorial approach to determine functional group effects on lipidoid-mediated siRNA delivery. Bioconjugate chemistry\| PubMed ID: 20715849	2010
Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells. Nature materials\| PubMed ID: 20729850	2010
CanScript, an 18-Base pair DNA sequence, boosts tumor cell-specific promoter activity: implications for targeted gene therapy. Cancer biology & therapy\| PubMed ID: 20798601	2010
A high throughput micro-array system of polymer surfaces for the manipulation of primary pancreatic islet cells. Biomaterials\| PubMed ID: 20828808	2010
Polymer surface functionalities that control human embryoid body cell adhesion revealed by high throughput surface characterization of combinatorial material microarrays. Biomaterials\| PubMed ID: 20832108	2010
An injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate. Biomaterials\| PubMed ID: 20880573	2011
High throughput surface characterization: A review of a new tool for screening prospective biomedical material arrays. Journal of drug targeting\| PubMed ID: 20945971	2010
DNA-controlled assembly of a NaTl lattice structure from gold nanoparticles and protein nanoparticles. Nature materials\| PubMed ID: 20953184	2010
Real-time in vivo detection of biomaterial-induced reactive oxygen species. Biomaterials\| PubMed ID: 21146868	2011
A novel family of biodegradable poly(ester amide) elastomers. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 21394790	2011
Spatiotemporal effects of a controlled-release anti-inflammatory drug on the cellular dynamics of host response. Biomaterials\| PubMed ID: 21429573	2011
Chondrogenic priming adipose-mesenchymal stem cells for cartilage tissue regeneration. Pharmaceutical research\| PubMed ID: 21494923	2011
Development of cationic polymer coatings to regulate foreign-body responses. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 21567481	2011
Degradable polyelectrolyte multilayers that promote the release of siRNA. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 21574582	2011
Five years of siRNA delivery: spotlight on gold nanoparticles. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 21681985	2011
Poly(Î²-amino ester)-DNA complexes: time-resolved fluorescence and cellular transfection studies. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 21699928	2011
Synergistic silencing: combinations of lipid-like materials for efficacious siRNA delivery. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 21750531	2011
Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21784981	2011
Directing human embryonic stem cell differentiation by non-viral delivery of siRNA in 3D culture. Biomaterials\| PubMed ID: 21835461	2011
Nanoparticles targeting the infarcted heart. Nano letters\| PubMed ID: 21899318	2011
Islets transplanted in immunoisolation devices: a review of the progress and the challenges that remain. Endocrine reviews\| PubMed ID: 21951347	2011
The influence of scaffold elasticity on germ layer specification of human embryonic stem cells. Biomaterials\| PubMed ID: 21963156	2011
Therapeutic siRNA silencing in inflammatory monocytes in mice. Nature biotechnology\| PubMed ID: 21983520	2011
Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22065768	2011
Combinatorial library of lipidoids for in vitro DNA delivery. Bioconjugate chemistry\| PubMed ID: 22148515	2012
Alkane-modified short polyethyleneimine for siRNA delivery. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 22155553	2011
Treating metastatic cancer with nanotechnology. Nature reviews. Cancer\| PubMed ID: 22193407	2012
Action and Reaction: The Biological Response to siRNA and Its Delivery Vehicles. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 22252451	2012
Origins of tumor-associated macrophages and neutrophils. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22308361	2012