fertility-sparing-procedure-using-carbon-dioxide-fiber-laser

Fertility Sparing Procedure using Carbon Dioxide Fiber Laser Vaporization of Ovarian Endometrioma

The surgical management of endometrioma is still a matter of debate. Cystectomy, which is recognized as the standard technique, seems to be associated ...

San Raffaele Scientific Institute

Limited attention has been focused on the medical treatment of bowel endometriosis. This study evaluates the efficacy of administration of a continuous low-dose oral contraceptive in treating pain and other symptoms associated with colorectal endometriotic nodules, as evaluated by rectal endoscopic ultrasonography.

Continuous low-dose oral contraceptive in the treatment of colorectal endometriosis evaluated by rectal endoscopic ultrasonography.

The revised American Society for Reproductive Medicine classification of endometriosis has a limited predictive value for pregnancy after surgery. A tool for predicting spontaneous pregnancy or pregnancy following assisted reproduction technology (ART) represents a clinical need. This study aimed to (i) provide an external validation of the EFI score in predicting pregnancy in infertile Italian endometriosis women; (ii) evaluate the predictive value of EFI score on ART outcome for patients who previously attempted to spontaneously conceive after surgery.

External validation of the endometriosis fertility index (EFI) for predicting spontaneous pregnancy after surgery: further considerations on its validity.

The advent of flexible CO2 laser fiber to gynecology arena might represent a turning point in the use of laser energy on a large-scale basis in gynecological surgery. However, there might be some concerns regarding the degree of surgical skills required to use the flexible system. The purpose of our study is to evaluate whether flexible CO2 laser fiber is technically accessible.

Flexible CO2 laser fiber: first look at the learning curve required in gynecological laparoscopy training.

To describe our technique for transvaginal treatment of isthmocele.

Mini-invasive transvaginal repair of isthmocele: a video case report.

To evaluate the treatment of patients with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome with a combination of oocyte retrieval and surgical vaginoplasty in a single laparoscopic procedure.

Oocyte Retrieval during Laparoscopic Vaginoplasty to Reduce Invasiveness in the Treatment of Mayer-Rokitansky-Küster-Hauser Syndrome.

To assess postoperative recurrence rates in patients with endometriomas managed by either "one-step" CO fiber laser vaporization or cystectomy.

Recurrence Rate after "One-Step" CO Fiber Laser Vaporization versus Cystectomy for Ovarian Endometrioma: A 3-Year Follow-up Study.

Data about endometrioma ablation using energies with little thermal spread reported good results in terms of ovarian reserve and postoperative pregnancy rates. The aim of the present study was to assess the impact of one step CO<inf>2</inf> fiber laser vaporization for endometrioma on subsequent controlled ovarian stimulation.

Ovarian responsiveness in assisted reproductive technology after CO2 fiber laser vaporization for endometrioma treatment: preliminary data.

To assess the postoperative likelihood of conception in patients with endometriomas managed by either CO laser vaporization or cystectomy.

Fertility Outcome after CO Laser Vaporization versus Cystectomy in Women with Ovarian Endometrioma: A Comparative Study.

Ovarian endometriosis may increase the risk of malignancy. Several studies have suggested atypical endometriosis as the direct precursor of endometriosis-associated ovarian cancer. We performed an advanced, systematic search of the online medical databases PubMed and Medline. The search revealed  = 40 studies eligible for inclusion in this systematic review. Of these,  = 39 were finally included. The results from included studies are characterized by high heterogeneity, but some consistency has been found for altered expression in phosphoinositide 3-kinase (PI3K)/AKT/mTOR pathway, ARID1a, estrogen and progesterone receptors, transcriptional, nuclear, and growth factors in atypical endometriosis. Although many targets have been proposed as biomarkers for the presence of atypical endometriosis, none of them has such strong evidence to justify their systematic use in clinical practice, and they all need expensive molecular analyses. Further well-designed studies are needed to validate the evidence on available biomarkers and to investigate novel serum markers for atypical endometriosis.

Article	Year
Continuous low-dose oral contraceptive in the treatment of colorectal endometriosis evaluated by rectal endoscopic ultrasonography. Acta obstetricia et gynecologica Scandinavica\| PubMed ID: 22268632	2012
External validation of the endometriosis fertility index (EFI) for predicting spontaneous pregnancy after surgery: further considerations on its validity. Gynecologic and obstetric investigation\| PubMed ID: 25634444	2015
Flexible CO2 laser fiber: first look at the learning curve required in gynecological laparoscopy training. Minerva ginecologica\| PubMed ID: 28994558	2018
Mini-invasive transvaginal repair of isthmocele: a video case report. Fertility and sterility\| PubMed ID: 30853089	2019
Oocyte Retrieval during Laparoscopic Vaginoplasty to Reduce Invasiveness in the Treatment of Mayer-Rokitansky-Küster-Hauser Syndrome. Journal of minimally invasive gynecology\| PubMed ID: 31129299	2020
Recurrence Rate after "One-Step" CO Fiber Laser Vaporization versus Cystectomy for Ovarian Endometrioma: A 3-Year Follow-up Study. Journal of minimally invasive gynecology\| PubMed ID: 31377455	2020
Ovarian responsiveness in assisted reproductive technology after CO2 fiber laser vaporization for endometrioma treatment: preliminary data. Minerva endocrinologica\| PubMed ID: 32638581	2020
Fertility Outcome after CO Laser Vaporization versus Cystectomy in Women with Ovarian Endometrioma: A Comparative Study. Journal of minimally invasive gynecology\| PubMed ID: 32712323	2021
A Systematic Review of Atypical Endometriosis-Associated Biomarkers. International journal of molecular sciences\| PubMed ID: 35457244	2022

Iacopo Tandoi

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