Rakesh Aggarwal

Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences

Affiliated withSanjay Gandhi Postgraduate Institute of Medical Sciences

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2022

Other Publications

Article	Year
Role of travel as a risk factor for hepatitis E virus infection in a disease-endemic area. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 11871830	2002
Evidence for activation of cellular immune responses in patients with acute hepatitis E. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 12385543	2002
Strongyloides stercoralis infestation associated with septicemia due to intestinal transmural migration of bacteria. Journal of gastroenterology and hepatology\| PubMed ID: 12423282	2002
Treatment of chronic hepatitis B with interferon-alpha: cost-effectiveness in developing countries. The National medical journal of India\| PubMed ID: 12540064	2002
Assessment of cost-effectiveness of universal hepatitis B immunization in a low-income country with intermediate endemicity using a Markov model. Journal of hepatology\| PubMed ID: 12547411	2003
Tropical sprue is associated with contamination of small bowel with aerobic bacteria and reversible prolongation of orocecal transit time. Journal of gastroenterology and hepatology\| PubMed ID: 12702046	2003
Piperacillin induced bone marrow suppression: a case report. BMC clinical pharmacology\| PubMed ID: 12791166	2003
Recurrent duodenal ulcer haemorrhage: a pharmacoeconomic comparison of various management strategies. Expert opinion on pharmacotherapy\| PubMed ID: 12943489	2003
Occult hepatitis B virus infection as a cause of cirrhosis of liver in a region with intermediate endemicity. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 12962434	2003
Frequency of infection by hepatitis B virus and its surface mutants in a northern Indian population. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 12962435	2003
Hepatic encephalopathy in pregnancy. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 15025263	2003
Hepatitis E virus is responsible for decompensation of chronic liver disease in an endemic region. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 15176538	2004
Etiological spectrum of sporadic malabsorption syndrome in northern Indian adults at a tertiary hospital. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 15250566	2004
Severe ulcerative colitis: prospective study of parameters determining outcome. Journal of gastroenterology and hepatology\| PubMed ID: 15482530	2004
Preventing and treating hepatitis B infection. BMJ (Clinical research ed.)\| PubMed ID: 15528620	2004
Hepatitis B virus genotype A is more often associated with severe liver disease in northern India than is genotype D. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 15778521	2005
Immunological alterations in pregnant women with acute hepatitis E. Journal of gastroenterology and hepatology\| PubMed ID: 15955220	2005
Profile of liver involvement in dengue virus infection. The National medical journal of India\| PubMed ID: 16130612	2005
Hepatitis B virus carriers; natural course, diagnostic approach and treatment. Tropical gastroenterology : official journal of the Digestive Diseases Foundation\| PubMed ID: 16225046	2005
Low frequency of factor V Leiden and prothrombin G20210A mutations in patients with hepatic venous outflow tract obstruction in northern India: a case-control study. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 16361766	2005
A boost to hepatitis B vaccine: no need for boosters. The National medical journal of India\| PubMed ID: 16483032	2005
Superior sagittal sinus thrombosis and Budd-Chiari syndrome due to paroxysmal nocturnal hemoglobinuria managed with transjugular intrahepatic portosystemic shunt: a case report. Tropical gastroenterology : official journal of the Digestive Diseases Foundation\| PubMed ID: 16512467	2005
HFE, hepcidin and ferroportin gene mutations are not present in Indian patients with primary haemochromatosis. The National medical journal of India\| PubMed ID: 16570681	2006
Antibody testing in Indian children with celiac disease. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 16877825	2006
Does co-infection with multiple viruses adversely influence the course and outcome of sporadic acute viral hepatitis in children? Journal of gastroenterology and hepatology\| PubMed ID: 16928213	2006
Factor V Leiden and prothrombin gene G20210A mutations are uncommon in portal vein thrombosis in India. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 17090840	2006
Cellular immune responses in acute hepatitis E virus infection to the viral open reading frame 2 protein. Viral immunology\| PubMed ID: 17425421	2007
Role of zinc administration in prevention of childhood diarrhea and respiratory illnesses: a meta-analysis. Pediatrics\| PubMed ID: 17545379	2007
Effect of a gluten-free diet on growth and small-bowel histology in children with celiac disease in India. Journal of gastroenterology and hepatology\| PubMed ID: 17565588	2007
Prediction of large esophageal varices in patients with cirrhosis of the liver using clinical, laboratory and imaging parameters. Journal of gastroenterology and hepatology\| PubMed ID: 17914969	2007
Presence of hepatitis E virus in sewage in Northern India: frequency and seasonal pattern. Journal of medical virology\| PubMed ID: 17935174	2007
Hepatitis A vaccine versus immunoglobulin for post-exposure prophylaxis. The National medical journal of India\| PubMed ID: 18335798	2007
Hepatitis E: does it cause chronic hepatitis? Hepatology (Baltimore, Md.)\| PubMed ID: 18821611	2008
Role of IgG anti-beta-lactoglobulin antibody in the diagnosis of cow's milk protein intolerance in India. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 19112188	2008
Clinical features and predictors of outcome in acute hepatitis A and hepatitis E virus hepatitis on cirrhosis. Liver international : official journal of the International Association for the Study of the Liver\| PubMed ID: 19267864	2009
Hepatitis E vaccine. Hepatology international\| PubMed ID: 19669259	2008
Epidemiology of hepatitis E: current status. Journal of gastroenterology and hepatology\| PubMed ID: 19686410	2009
Medical literature and Chinese whispers. The National medical journal of India\| PubMed ID: 20334048	2009
Viral RNA but no evidence of replication can be detected in the peripheral blood mononuclear cells of hepatitis E virus-infected patients. Journal of viral hepatitis\| PubMed ID: 20659304	2011
Evidence of hepatitis E virus exposure among seronegative healthy residents of an endemic area. Intervirology\| PubMed ID: 20962536	2011
Adaptive immune responses during acute uncomplicated and fulminant hepatitis E. Journal of gastroenterology and hepatology\| PubMed ID: 21143520	2011
Prevention of hepatitis E: another step forward. Future microbiology\| PubMed ID: 21162633	2011
Hepatitis E: Historical, contemporary and future perspectives. Journal of gastroenterology and hepatology\| PubMed ID: 21199517	2011
Plasma peptidome profiling of acute hepatitis E patients by MALDI-TOF/TOF. Proteome science\| PubMed ID: 21294899	2011
Clinical presentation of hepatitis E. Virus research\| PubMed ID: 21458513	2011
Hepatitis E: another effective vaccine, but will it make a difference? The National medical journal of India\| PubMed ID: 21608356	2011
A comparison of online versus on-site training in health research methodology: a randomized study. BMC medical education\| PubMed ID: 21682858	2011
Hepatitis E. Hepatology (Baltimore, Md.)\| PubMed ID: 21932388	2011
Histological and immunohistochemical features in fatal acute fulminant hepatitis E. Indian journal of pathology & microbiology\| PubMed ID: 22499295	2012
Effect of maternal education on choice of location for delivery among Indian women. The National medical journal of India\| PubMed ID: 22680256	2011
Non-organ-specific autoantibodies in Indian patients with chronic liver disease. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 22941677	2012
Diagnosis of hepatitis E. Nature reviews. Gastroenterology & hepatology\| PubMed ID: 23026902	2013
Spectrum of malabsorption syndrome among adults & factors differentiating celiac disease & tropical malabsorption. The Indian journal of medical research\| PubMed ID: 23041739	2012
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet\| PubMed ID: 23245607	2012
Prediction of essential proteins in prokaryotes by incorporating various physico-chemical features into the general form of Chou's pseudo amino acid composition. Protein and peptide letters\| PubMed ID: 23276224	2013
Hepatitis E: clinical presentation in disease-endemic areas and diagnosis. Seminars in liver disease\| PubMed ID: 23564387	2013
Unconjugated hyperbilirubinemia: a blessing in disguise? Journal of gastroenterology and hepatology\| PubMed ID: 24147453	2013
Gut microbiota and liver disease. Journal of gastroenterology and hepatology\| PubMed ID: 24547986	2014
Need for immunization against hepatotropic viruses in children with chronic liver disease. Journal of pediatric gastroenterology and nutrition\| PubMed ID: 24840513	2014
Frequency of SPINK1 N34S mutation in acute and recurrent acute pancreatitis. Journal of hepato-biliary-pancreatic sciences\| PubMed ID: 24844923	2014
N-acetyltransferase and cytochrome P450 2E1 gene polymorphisms and susceptibility to antituberculosis drug hepatotoxicity in an Indian population. The National medical journal of India\| PubMed ID: 25017831	2013
Lack of persistent hepatitis E virus infection as a cause for unexplained transaminase elevation in renal transplant recipients in India. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 25266354	2014
Effect of inclusion of hepatitis B vaccine in childhood immunization program in India: a retrospective cohort study. Indian pediatrics\| PubMed ID: 25432216	2014
Proteome mining for drug target identification in Listeria monocytogenes strain EGD-e and structure-based virtual screening of a candidate drug target penicillin binding protein 4. Journal of microbiological methods\| PubMed ID: 25601791	2015
Hepatitis e: epidemiology and natural history. Journal of clinical and experimental hepatology\| PubMed ID: 25755486	2013
Consensus Statement of HCV Task Force of the Indian National Association for Study of the Liver (INASL). Part I: Status Report of HCV Infection in India. Journal of clinical and experimental hepatology\| PubMed ID: 25755548	2014
Occult hepatitis B infection in children with chronic liver disease. European journal of gastroenterology & hepatology\| PubMed ID: 25874508	2015
Prevalence of hepatitis D virus infection among hepatitis B virus-infected individuals in India. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 25902955	2015
Changes in gene expression in liver tissue from patients with fulminant hepatitis E. World journal of gastroenterology\| PubMed ID: 26185374	2015
Hepatitis A: epidemiology in resource-poor countries. Current opinion in infectious diseases\| PubMed ID: 26203853	2015
Acute Hepatitis E-Associated Acute Pancreatitis: A Single Center Experience and Literature Review. Pancreas\| PubMed ID: 26390412	2015
Common pitfalls in statistical analysis: Odds versus risk. Perspectives in clinical research\| PubMed ID: 26623395	2015
Indian National Association for Study of the Liver (INASL) Guidance for Antiviral Therapy Against HCV Infection in 2015. Journal of clinical and experimental hepatology\| PubMed ID: 26628840	2015
Identification of Promotor and Exonic Variations, and Functional Characterization of a Splice Site Mutation in Indian Patients with Unconjugated Hyperbilirubinemia. PloS one\| PubMed ID: 26716871	2015
The revised guidelines of the Medical Council of India for academic promotions: need for a rethink. Indian journal of medical ethics\| PubMed ID: 26826653	2016
Hepatitis B vaccine: Using skin when muscle does not work. Journal of gastroenterology and hepatology\| PubMed ID: 26919542	2016
Screening Transfusions for Hepatitis E Virus: Is it needed in India? The National medical journal of India\| PubMed ID: 27132948	2015
Advances in hepatitis E - II: Epidemiology, clinical manifestations, treatment and prevention. Expert review of gastroenterology & hepatology\| PubMed ID: 27148907	2016
Advances in hepatitis E - I: virology, pathogenesis and diagnosis. Expert review of gastroenterology & hepatology\| PubMed ID: 27159083	2016
Identification of autoimmune polyendocrine syndrome type 1 in patients with isolated hypoparathyroidism. Clinical endocrinology\| PubMed ID: 27219120	2016
Prevalence, severity, and impact on quality of life of restless leg syndrome in patients with liver cirrhosis in India. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 27225798	2016
Gastrointestinal Stromal Tumor: Genotype Frequency and Prognostic Relevance. Applied immunohistochemistry & molecular morphology : AIMM\| PubMed ID: 27258566	2018
Safety and effectiveness of response-guided therapy using pegylated interferon and ribavirin for chronic hepatitis C virus infection in patients on maintenance dialysis. Nephrology (Carlton, Vic.)\| PubMed ID: 27286895	2017
Common pitfalls in statistical analysis: Intention-to-treat versus per-protocol analysis. Perspectives in clinical research\| PubMed ID: 27453832	2016
Low frequency of V617F mutation in JAK2 gene in Indian patients with hepatic venous outflow obstruction and extrahepatic portal venous obstruction. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 27633031	2016
Common pitfalls in statistical analysis: The use of correlation techniques. Perspectives in clinical research\| PubMed ID: 27843795	2016
A Novel Truncation Mutation in ATP8B1 Gene in Progressive Familial Intrahepatic Cholestasis. Indian pediatrics\| PubMed ID: 28064265	2016
Experience with direct acting anti-viral agents for treating hepatitis C virus infection in renal transplant recipients. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 28345112	2017
Common pitfalls in statistical analysis: Linear regression analysis. Perspectives in clinical research\| PubMed ID: 28447022	2017
Cost-effectiveness of hepatitis C treatment using generic direct-acting antivirals available in India. PloS one\| PubMed ID: 28520728	2017
Treatment of chronic genotype-3 hepatitis C virus infection using direct-acting antiviral agents: An Indian experience. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 28656492	2017
Hepatitis C Virus: Discovery to epitaph in a life-time. The National medical journal of India\| PubMed ID: 28816209	2017
Common pitfalls in statistical analysis: Logistic regression. Perspectives in clinical research\| PubMed ID: 28828311	2017
Common pitfalls in statistical analysis: Measures of agreement. Perspectives in clinical research\| PubMed ID: 29109937	2017
Hepatitis E virus infection. Nature reviews. Disease primers\| PubMed ID: 29154369	2017
Novel Synthesis and Phenotypic Analysis of Mutant Clouds for Hepatitis E Virus Genotype 1. Journal of virology\| PubMed ID: 29167341	2018
Faecal bacterial microbiota in patients with cirrhosis and the effect of lactulose administration. BMC gastroenterology\| PubMed ID: 29179682	2017
Daclatasvir and reduced-dose sofosbuvir: An effective and pangenotypic treatment for hepatitis C in patients with estimated glomerular filtration rate <30 mL/min. Nephrology (Carlton, Vic.)\| PubMed ID: 29327401	2019
Medical Council of India's amended qualifications for Indian medical teachers: Well intended, yet half-hearted. Indian journal of urology : IJU : journal of the Urological Society of India\| PubMed ID: 29343904	2018
Endoscopic ultrasound-guided choledochoduodenostomy using partially-covered self-expandable metal stent in patients with malignant distal biliary obstruction and unsuccessful ERCP. Endoscopy international open\| PubMed ID: 29344562	2018
Acute hepatitis E in India appears to be caused exclusively by genotype 1 hepatitis E virus. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 29399748	2018
Common pitfalls in statistical analysis: Understanding the properties of diagnostic tests - Part 1. Perspectives in clinical research\| PubMed ID: 29430417	2018
Medical Council of India's amended qualifications for Indian medical teachers: Well intended, yet half-hearted. Indian journal of medical ethics\| PubMed ID: 29439938	2017
Medical Council of India's amended qualifications for Indian medical teachers: Well intended, yet half-hearted. Journal of anaesthesiology, clinical pharmacology\| PubMed ID: 29643613	2018
Natural History, Clinical Manifestations, and Pathogenesis of Hepatitis E Virus Genotype 1 and 2 Infections. Cold Spring Harbor perspectives in medicine\| PubMed ID: 29735580	2019
Estimation of Hepatitis C Disease Burden and Budget Impact of Treatment Using Health Economic Modeling. Infectious disease clinics of North America\| PubMed ID: 29778266	2018
Genotyping of hepatitis B virus isolates from Lahaul and Spiti district in Himachal Pradesh, India. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 29855856	2018
Understanding the properties of diagnostic tests - Part 2: Likelihood ratios. Perspectives in clinical research\| PubMed ID: 29862204	2018
Cost-effectiveness of generic pan-genotypic sofosbuvir/velpatasvir versus genotype-dependent direct-acting antivirals for hepatitis C treatment. Journal of gastroenterology and hepatology\| PubMed ID: 29864213	2018
Relationship of Severity of Hepatitis A with Polymorphisms in Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Gene. Annals of hepatology\| PubMed ID: 29893695	2018
Effect of administration of a probiotic preparation on gut microbiota and immune response in healthy women in India: an open-label, single-arm pilot study. BMC gastroenterology\| PubMed ID: 29907093	2018
Spectrum of genomic variations in Indian patients with progressive familial intrahepatic cholestasis. BMC gastroenterology\| PubMed ID: 29973134	2018
Endoscopic ultrasound-guided coil and glue for treatment of splenic artery pseudo-aneurysm: new kid on the block! Endoscopy international open\| PubMed ID: 29978000	2018
Understanding diagnostic tests - Part 3: Receiver operating characteristic curves. Perspectives in clinical research\| PubMed ID: 30090714	2018
Medical Council of India's amended qualifications for Indian medical teachers: Well intended, yet half-hearted. Indian journal of cancer\| PubMed ID: 30147085	2018
Prevalence of hepatitis E virus viremia and antibodies among healthy blood donors in India. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 30159666	2018
Burden of hepatitis C virus infection in India: A systematic review and meta-analysis. Journal of gastroenterology and hepatology\| PubMed ID: 30176181	2019
Interaction of miR-125b-5p with Human antigen R mRNA: Mechanism of controlling HCV replication. Virus research\| PubMed ID: 30253192	2018
Study designs: Part 1 - An overview and classification. Perspectives in clinical research\| PubMed ID: 30319950	2018
Statistical literacy for healthcare professionals: Why is it important? Annals of cardiac anaesthesia\| PubMed ID: 30333326	2018
Medical Council of India's Amended Qualifications for Indian Medical Teachers: Well intended, yet half-hearted. The National medical journal of India\| PubMed ID: 30348911	2018
Hep C Calculator: an online tool for cost-effectiveness analysis of DAAs. The lancet. Gastroenterology & hepatology\| PubMed ID: 30507463	2018
Epidemiology of hepatitis B and C viral infections in Ladakh region. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 30543047	2018
Hepatitis C virus infection and chronic renal disease: A review. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 30560540	2018
INASL Guidelines on Management of Hepatitis B Virus Infection in Patients receiving Chemotherapy, Biologicals, Immunosupressants, or Corticosteroids. Journal of clinical and experimental hepatology\| PubMed ID: 30568345	2018
Methods for Studying Gut Microbiota: A Primer for Physicians. Journal of clinical and experimental hepatology\| PubMed ID: 30774267	2019
Study designs: Part 2 - Descriptive studies. Perspectives in clinical research\| PubMed ID: 30834206	2019
Hepatitis E: The endemic perspective. Clinical liver disease\| PubMed ID: 30992872	2013
Hepatitis E should be considered a neglected tropical disease. PLoS neglected tropical diseases\| PubMed ID: 31344038	2019
Liver disease severity is poorly related to the presence of restless leg syndrome in patients with cirrhosis. Neurology India\| PubMed ID: 31347545	2019
Indian National Association for the Study of the Liver-Federation of Obstetric and Gynaecological Societies of India Position Statement on Management of Liver Diseases in Pregnancy. Journal of clinical and experimental hepatology\| PubMed ID: 31360030	2019
Occurrence of disease after natural disasters does not follow a set pattern. The National medical journal of India\| PubMed ID: 31397381	2018
Genome-Wide Mutagenesis of Hepatitis C Virus Reveals Ability of Genome To Overcome Detrimental Mutations. Journal of virology\| PubMed ID: 31723027	2020
Liver diseases in the Asia-Pacific region: a Lancet Gastroenterology & Hepatology Commission. The lancet. Gastroenterology & hepatology\| PubMed ID: 31852635	2020
Temporal profile of HEV RNA concentration in blood and stool from patients with acute uncomplicated hepatitis E in a region with genotype 1 predominance. Journal of viral hepatitis\| PubMed ID: 31997507	2020
2019 Update of Indian National Association for Study of the Liver Consensus on Prevention, Diagnosis, and Management of Hepatocellular Carcinoma in India: The Puri II Recommendations. Journal of clinical and experimental hepatology\| PubMed ID: 32025166	2020
Prevalence of hepatitis E viraemia among blood donors: a systematic review. Vox sanguinis\| PubMed ID: 32030767	2020
Construction & assessment of a unified curated reference database for improving the taxonomic classification of bacteria using 16S rRNA sequence data. The Indian journal of medical research\| PubMed ID: 32134020	2020
Joint Guidance from SGEI, ISG and INASL for Gastroenterologists and Gastrointestinal Endoscopists on the Prevention, Care, and Management of Patients With COVID-19. Journal of clinical and experimental hepatology\| PubMed ID: 32362732	2020
Blood transfusion is unlikely to be a source for hepatitis E virus transmission in India. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology\| PubMed ID: 32372189	2020
Hepatitis E: Epidemiology, Clinical Course, Prevention, and Treatment. Gastroenterology clinics of North America\| PubMed ID: 32389365	2020
Acute hepatitis C treatment in advanced renal failure using 8 weeks of pan-genotypic daclatasvir and reduced-dose sofosbuvir. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 33097949	2021
Viral suppression is comparable with 0.5 mg and 1.0 mg daily doses of entecavir in treatment-naive HBV-related decompensated cirrhosis. Antiviral therapy\| PubMed ID: 33404519	2020
INASL-ISN Joint Position Statements on Management of Patients with Simultaneous Liver and Kidney Disease. Journal of clinical and experimental hepatology\| PubMed ID: 33994718	2021
Covid-19 Vaccines: Several technologies at work. The National medical journal of India\| PubMed ID: 34396995	2021
Enhanced fitness of hepatitis C virus increases resistance to direct-acting antivirals. The Journal of general virology\| PubMed ID: 35133954	2022
Short course of low-dose pregabalin is effective for the treatment of restless leg syndrome in patients with cirrhosis: A pilot study. Journal of gastroenterology and hepatology\| PubMed ID: 35174537	2022
Seroprevalence and burden of hepatitis C virus infection in WHO South-East Asia Region: A systematic review. Journal of gastroenterology and hepatology\| PubMed ID: 35263807	2022
Serum Bile Acid Levels in Women With Intrahepatic Cholestasis of Pregnancy in India. Journal of clinical and experimental hepatology\| PubMed ID: 35535067	2022