Raymond R. Mattingly

Department of Pharmacology, Wayne State University

Research Area

Biography

Raymond R. Mattingly has not added Biography.
If you are Raymond R. Mattingly and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 43	2012

Other Publications

Article	Year
High RhoA activity maintains the undifferentiated mesenchymal cell phenotype, whereas RhoA down-regulation by laminin-2 induces smooth muscle myogenesis. The Journal of cell biology\| PubMed ID: 11877460	2002
Mechanism of 17-beta-estradiol-induced Erk1/2 activation in breast cancer cells. A role for HER2 AND PKC-delta. The Journal of biological chemistry\| PubMed ID: 11960991	2002
Potent suppression of proliferation of a10 vascular smooth muscle cells by combined treatment with lovastatin and 3-allylfarnesol, an inhibitor of protein farnesyltransferase. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 12235235	2002
Phosphorylation of the Ras-GRF1 exchange factor at Ser916/898 reveals activation of Ras signaling in the cerebral cortex. The Journal of biological chemistry\| PubMed ID: 12538592	2003
Mitogen-activated protein kinase signaling in drug-resistant neuroblastoma cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 12616713	2003
Cell surface receptors activate p21-activated kinase 1 via multiple Ras and PI3-kinase-dependent pathways. Cellular signalling\| PubMed ID: 14575865	2003
Gbetagamma subunits stimulate p21-activated kinase 1 (PAK1) through activation of PI3-kinase and Akt but act independently of Rac1/Cdc42. FEBS letters\| PubMed ID: 14706848	2004
TNF-alpha-mediated apoptosis in normal human prostate epithelial cells and tumor cell lines. Cancer letters\| PubMed ID: 14732222	2004
Angiotensin II directly stimulates activity and alters the phosphorylation of Na-K-ATPase in rat proximal tubule with a rapid time course. American journal of physiology. Renal physiology\| PubMed ID: 15161602	2004
Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells. The FEBS journal\| PubMed ID: 15853814	2005
Active p21-activated kinase 1 rescues MCF10A breast epithelial cells from undergoing anoikis. Neoplasia (New York, N.Y.)\| PubMed ID: 16026643	2005
The mitogen-activated protein kinase/extracellular signal-regulated kinase kinase inhibitor PD184352 (CI-1040) selectively induces apoptosis in malignant schwannoma cell lines. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 16239399	2006
Inorganic mercury inhibits the activation of LAT in T-cell receptor-mediated signal transduction. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 16251484	2006
The Ras-GRF1 exchange factor coordinates activation of H-Ras and Rac1 to control neuronal morphology. Molecular biology of the cell\| PubMed ID: 16481401	2006
Molecular targets for emerging anti-tumor therapies for neurofibromatosis type 1. Biochemical pharmacology\| PubMed ID: 16797490	2006
Epac- and Rap- independent ERK1/2 phosphorylation induced by Gs-coupled receptor stimulation in HEK293 cells. FEBS letters\| PubMed ID: 17174312	2007
Synthesis, biochemical, and cellular evaluation of farnesyl monophosphate prodrugs as farnesyltransferase inhibitors. Journal of medicinal chemistry\| PubMed ID: 17555307	2007
Low and nontoxic inorganic mercury burdens attenuate BCR-mediated signal transduction. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 17656488	2007
Angiotensin II stimulates elution of Na-K-ATPase from a digoxin-affinity column by increasing the kinetic response to ligands that trigger the decay of E2-P. American journal of physiology. Renal physiology\| PubMed ID: 18272598	2008
Induction of apoptosis in neurofibromatosis type 1 malignant peripheral nerve sheath tumor cell lines by a combination of novel farnesyl transferase inhibitors and lovastatin. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 18367665	2008
p21-Activated kinase 1 coordinates aberrant cell survival and pericellular proteolysis in a three-dimensional culture model for premalignant progression of human breast cancer. Neoplasia (New York, N.Y.)\| PubMed ID: 18392133	2008
Suppression of proliferation of two independent NF1 malignant peripheral nerve sheath tumor cell lines by the pan-ErbB inhibitor CI-1033. Cancer biology & therapy\| PubMed ID: 18927496	2008
Restoration of E-cadherin cell-cell junctions requires both expression of E-cadherin and suppression of ERK MAP kinase activation in Ras-transformed breast epithelial cells. Neoplasia (New York, N.Y.)\| PubMed ID: 19048123	2008
Three-dimensional overlay culture models of human breast cancer reveal a critical sensitivity to mitogen-activated protein kinase kinase inhibitors. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 19952304	2010
A novel geranylgeranyl transferase inhibitor in combination with lovastatin inhibits proliferation and induces autophagy in STS-26T MPNST cells. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 20086055	2010
Working together: Farnesyl transferase inhibitors and statins block protein prenylation. Molecular and cellular pharmacology\| PubMed ID: 20419048	2009
The role of neurofibromin in N-Ras mediated AP-1 regulation in malignant peripheral nerve sheath tumors. Molecular and cellular biochemistry\| PubMed ID: 20680410	2010
Aborted autophagy and nonapoptotic death induced by farnesyl transferase inhibitor and lovastatin. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 21228063	2011
Angiotensin II-dependent Phosphorylation at Ser-11/Ser-18 and Ser-938 shift the E2 Conformations of Rat Kidney Na,K-ATPase. The Biochemical journal\| PubMed ID: 22145807	2011