Bonnie F. Sloane

Department of Pharmacology, Wayne State University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 43	2012

Other Publications

Article	Year
Cathepsin B and D are Localized at the Surface of Human Breast Cancer Cells. Pathology oncology research : POR\| PubMed ID: 11173567	1995
Analysis of a truncated form of cathepsin H in human prostate tumor cells. The Journal of biological chemistry\| PubMed ID: 11796715	2002
Evidence for the involvement of cathepsin B in skeletal myoblast differentiation. Journal of cellular biochemistry\| PubMed ID: 11813257	2002
Phorbol ester activation of a proteolytic cascade capable of activating latent transforming growth factor-betaL a process initiated by the exocytosis of cathepsin B. The Journal of biological chemistry\| PubMed ID: 11815600	2002
Interaction of human breast fibroblasts with collagen I increases secretion of procathepsin B. The Journal of biological chemistry\| PubMed ID: 12072442	2002
Selective inhibition of cathepsin B with cell-permeable CA074Me negatively affects L6 rat myoblast differentiation. Biochemistry and cell biology = Biochimie et biologie cellulaire\| PubMed ID: 12234099	2002
Determination of cathepsin B expression may offer additional prognostic information for ovarian cancer patients. Biological chemistry\| PubMed ID: 12437120	2002
Degradation of extracellular matrix protein tenascin-C by cathepsin B: an interaction involved in the progression of gliomas. Biological chemistry\| PubMed ID: 12437133	2002
Evidence that E-box promoter elements and MyoD transcription factors play a role in the induction of cathepsin B gene expression during human myoblast differentiation. Biological chemistry\| PubMed ID: 12553720	2002
Cell-surface cathepsin B: understanding its functional significance. Current topics in developmental biology\| PubMed ID: 12696754	2003
Invasiveness of transformed human breast epithelial cell lines is related to cathepsin B and inhibited by cysteine proteinase inhibitors. Biological chemistry\| PubMed ID: 12715895	2003
Pericellular cathepsin B and malignant progression. Cancer metastasis reviews\| PubMed ID: 12785001	2003
Molecular regulation of human cathepsin B: implication in pathologies. Biological chemistry\| PubMed ID: 12887051	2003
Cathepsin B and its role(s) in cancer progression. Biochemical Society symposium\| PubMed ID: 14587299	2003
Functional imaging of proteolysis: stromal and inflammatory cells increase tumor proteolysis. Molecular imaging\| PubMed ID: 14649059	2003
Transcription of cathepsin B in glioma cells: regulation by an E-box adjacent to the transcription initiation site. Biological chemistry\| PubMed ID: 14669984	2003
Cystatin M suppresses the malignant phenotype of human MDA-MB-435S cells. Oncogene\| PubMed ID: 14676833	2004
Mutant K-ras regulates cathepsin B localization on the surface of human colorectal carcinoma cells. Neoplasia (New York, N.Y.)\| PubMed ID: 14965444	2003
Proteases, extracellular matrix, and cancer: a workshop of the path B study section. The American journal of pathology\| PubMed ID: 15039201	2004
Differential susceptibilities of murine hepatoma 1c1c7 and Tao cells to the lysosomal photosensitizer NPe6: influence of aryl hydrocarbon receptor on lysosomal fragility and protease content... Molecular pharmacology\| PubMed ID: 15044632	2004
Isolation of a novel USF2 isoform: repressor of cathepsin B expression. Gene\| PubMed ID: 15276216	2004
Cystatin m: a novel candidate tumor suppressor gene for breast cancer. Cancer research\| PubMed ID: 15466187	2004
Cysteine cathepsins in human cancer. Biological chemistry\| PubMed ID: 15576321	2004
Cathepsin B and tumor proteolysis: contribution of the tumor microenvironment. Seminars in cancer biology\| PubMed ID: 15652460	2005
Tissue inhibitor of metalloproteinase-1 protects human breast epithelial cells from extrinsic cell death: a potential oncogenic activity of tissue inhibitor of metalloproteinase-1. Cancer research\| PubMed ID: 15705888	2005
Caveolin-1 mediates the expression and localization of cathepsin B, pro-urokinase plasminogen activator and their cell-surface receptors in human colorectal carcinoma cells. Journal of cell science\| PubMed ID: 15769846	2005
Matrix metalloproteinase activity and osteoclasts in experimental prostate cancer bone metastasis tissue. The American journal of pathology\| PubMed ID: 15793297	2005
Bone microenvironment modulates expression and activity of cathepsin B in prostate cancer. Neoplasia (New York, N.Y.)\| PubMed ID: 15799821	2005
High yield synthesis and characterization of phosphorylated recombinant human procathepsin D expressed in mammalian cells. Protein expression and purification\| PubMed ID: 16242956	2006
Functional imaging of tumor proteolysis. Annual review of pharmacology and toxicology\| PubMed ID: 16402907	2006
Dynamic imaging of protease activity with fluorescently quenched activity-based probes. Nature chemical biology\| PubMed ID: 16408036	2005
Cathepsin B localizes to plasma membrane caveolae of differentiating myoblasts and is secreted in an active form at physiological pH. Biological chemistry\| PubMed ID: 16497156	2006
Cathepsin L splice variants in human breast cell lines. Biological chemistry\| PubMed ID: 16740135	2006
Loss of caspase-8 in tumor cells: mechanism to overcome integrin-mediated death? Molecular interventions\| PubMed ID: 16809473	2006
Analysis of host- and tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer. Cancer research\| PubMed ID: 16912171	2006
Cysteine cathepsins: multifunctional enzymes in cancer. Nature reviews. Cancer\| PubMed ID: 16990854	2006
I2 imaging: cancer biology and the tumor microenvironment. Cancer research\| PubMed ID: 17114235	2006
Functional expression of recombinant human stefin A in mammalian and bacterial cells. Protein expression and purification\| PubMed ID: 17208452	2007
Hu/Mu ProtIn oligonucleotide microarray: dual-species array for profiling protease and protease inhibitor gene expression in tumors and their microenvironment. Molecular cancer research : MCR\| PubMed ID: 17510311	2007
Increased carcinogenic potential of myeloid tumor cells induced by aberrant TGF-beta1-signaling and upregulation of cathepsin B. Biological chemistry\| PubMed ID: 17552911	2007
Cysteine cathepsin non-inhibitory binding partners: modulating intracellular trafficking and function. Biological chemistry\| PubMed ID: 17976005	2007
Caveolin-1-mediated expression and secretion of kallikrein 6 in colon cancer cells. Neoplasia (New York, N.Y.)\| PubMed ID: 18283336	2008
p21-Activated kinase 1 coordinates aberrant cell survival and pericellular proteolysis in a three-dimensional culture model for premalignant progression of human breast cancer. Neoplasia (New York, N.Y.)\| PubMed ID: 18392133	2008
Visualizing protease activity in living cells: from two dimensions to four dimensions. Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.]\| PubMed ID: 18551423	2008
Human monocytes augment invasiveness and proteolytic activity of inflammatory breast cancer. Biological chemistry\| PubMed ID: 18710343	2008
Lysosomal cathepsin B participates in the podosome-mediated extracellular matrix degradation and invasion via secreted lysosomes in v-Src fibroblasts. Cancer research\| PubMed ID: 19010886	2008
Imaging and quantifying the dynamics of tumor-associated proteolysis. Clinical & experimental metastasis\| PubMed ID: 19082919	2009
Cathepsin B protein levels in endometrial cancer: Potential value as a tumour biomarker. Gynecologic oncology\| PubMed ID: 19110306	2009
Functional live-cell imaging demonstrates that beta1-integrin promotes type IV collagen degradation by breast and prostate cancer cells. Molecular imaging\| PubMed ID: 19123990	2008
Bicarbonate increases tumor pH and inhibits spontaneous metastases. Cancer research\| PubMed ID: 19276390	2009
Live-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation. Experimental cell research\| PubMed ID: 19331819	2009
Microarrays for protease detection in tissues and cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19377971	2009
Bone marrow-derived cathepsin K cleaves SPARC in bone metastasis. The American journal of pathology\| PubMed ID: 19700761	2009
Fibroblast hepatocyte growth factor promotes invasion of human mammary ductal carcinoma in situ. Cancer research\| PubMed ID: 19920187	2009
Chiral porphyrazine near-IR optical imaging agent exhibiting preferential tumor accumulation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20080563	2010
Interleukin-6 increases expression and secretion of cathepsin B by breast tumor-associated monocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 20110692	2010
Capturing and characterizing immune cells from breast tumor microenvironment: an innovative surgical approach. Annals of surgical oncology\| PubMed ID: 20333554	2010
Cathepsin B: a potential prognostic marker for inflammatory breast cancer. Journal of translational medicine\| PubMed ID: 21199580	2011
Aborted autophagy and nonapoptotic death induced by farnesyl transferase inhibitor and lovastatin. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 21228063	2011
Live-cell imaging of tumor proteolysis: Impact of cellular and non-cellular microenvironment. Biochimica et biophysica acta\| PubMed ID: 21854877	2012
Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasion. Breast cancer research : BCR\| PubMed ID: 22093547	2011
Cathepsin B inhibition limits bone metastasis in breast cancer. Cancer research\| PubMed ID: 22266111	2012
The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancer. BMC cancer\| PubMed ID: 22280365	2012