Evangelos D. Michelakis

Department of Medicine, University of Alberta

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2012

Other Publications

Article	Year
Circulation\| PubMed ID: 11790708	2002
Circulation research\| PubMed ID: 12089069	2002
O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor. Circulation research\| PubMed ID: 12242265	2002
American journal of physiology. Heart and circulatory physiology\| PubMed ID: 12388256	2002
Circulation\| PubMed ID: 12578883	2003
Heart failure reviews\| PubMed ID: 12652155	2003
In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats. Circulation\| PubMed ID: 12695303	2003
Circulation\| PubMed ID: 14568893	2003
Advances in experimental medicine and biology\| PubMed ID: 14713130	2003
Archives of internal medicine\| PubMed ID: 15006828	2004
O2 sensing in the human ductus arteriosus: redox-sensitive K+ channels are regulated by mitochondria-derived hydrogen peroxide. Biological chemistry\| PubMed ID: 15134333	2004
Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic ... Circulation research\| PubMed ID: 15217912	2004
FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 15333581	2004
Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus. Circulation\| PubMed ID: 15353504	2004
Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis. Circulation research\| PubMed ID: 15375007	2004
Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells. Journal of molecular and cellular cardiology\| PubMed ID: 15572043	2004
Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 15591309	2005
Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension. The Journal of clinical investigation\| PubMed ID: 15931388	2005
Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis part... Circulation\| PubMed ID: 16230500	2005
Drugs & aging\| PubMed ID: 16245957	2005
Circulation research\| PubMed ID: 16456109	2006
A central role for oxygen-sensitive K+ channels and mitochondria in the specialized oxygen-sensing system. Novartis Foundation symposium\| PubMed ID: 16686435	2006
An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human p... Circulation\| PubMed ID: 16735674	2006
Current opinion in cardiology\| PubMed ID: 16755209	2006
American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 16990484	2007
Absence of malonyl coenzyme A decarboxylase in mice increases cardiac glucose oxidation and protects the heart from ischemic injury. Circulation\| PubMed ID: 17030679	2006
Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 17085423	2006
American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 17142350	2007
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer cell\| PubMed ID: 17222789	2007
Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly r... Circulation\| PubMed ID: 17353442	2007
Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 17483441	2007
The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17596340	2007
Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility. Circulation\| PubMed ID: 17606845	2007
Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 17675370	2007
CD36 expression contributes to age-induced cardiomyopathy in mice. Circulation\| PubMed ID: 17967771	2007
Developmental absence of the O2 sensitivity of L-type calcium channels in preterm ductus arteriosus smooth muscle cells impairs O2 constriction contributing to patent ductus arteriosus. Pediatric research\| PubMed ID: 18091358	2008
Circulation\| PubMed ID: 18474822	2008
A dynamic and chamber-specific mitochondrial remodeling in right ventricular hypertrophy can be therapeutically targeted. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 18603070	2008
American journal of physiology. Heart and circulatory physiology\| PubMed ID: 18621852	2008
Circulation\| PubMed ID: 18824655	2008
American journal of physiology. Heart and circulatory physiology\| PubMed ID: 19411285	2009
American journal of physiology. Cell physiology\| PubMed ID: 19535513	2009
Journal of the American College of Cardiology\| PubMed ID: 19555853	2009
Dehydroepiandrosterone reverses systemic vascular remodeling through the inhibition of the Akt/GSK3-{beta}/NFAT axis. Circulation\| PubMed ID: 19752325	2009
Circulation\| PubMed ID: 19752350	2009
The New England journal of medicine\| PubMed ID: 19890129	2009
Current opinion in cardiology\| PubMed ID: 20130456	2010
Chest\| PubMed ID: 20522585	2010
Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension. Science translational medicine\| PubMed ID: 20702857	2010
Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 20734021	2010
Chest\| PubMed ID: 21540210	2011
The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension. Science translational medicine\| PubMed ID: 21697531	2011
Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 21809123	2011