isolation-culture-bone-marrow-mesenchymal-stem-cells-from-human

Isolation and Culture of Bone Marrow Mesenchymal Stem Cells from the Human Mandible

Human mesenchymal stem cells (hMSCs) have shown great potential in bone regeneration, immune modulation, and treating refractory chronic diseases. Various ...

The Fourth Military Medical University

Hydrogen, a therapeutic medical gas, can exert antioxidant activity via selectively reducing cytotoxic reactive oxygen species such as hydroxyl radicals. Hydrogen-rich saline is an alternative form of molecular hydrogen that has been widely used in many studies, including metabolic syndrome, cerebral, hepatic, myocardial ischemia/reperfusion, and liver injuries with obstructive jaundice, with beneficial results. Osteoradionecrosis of the jaw is a serious complication following radiotherapy for head and neck cancers. It has long been known that most radiation-induced symptoms are caused by free radicals generated by radiolysis of H2O, and the hydroxyl radical is the most reactive of these. Reducing the hydroxyl radical can distinctly improve the protection of cells from radiation damage. We hypothesized that hydrogen-rich saline might be an effective and specific method of managing and preventing osteoradionecrosis of the jaw. 

Hydrogen-rich saline may be an effective and specific novel treatment for osteoradionecrosis of the jaw.

The present study aimed to evaluate the feasibility, accuracy, and clinical effect of intraoperative navigation for resection of elongated styloid process (ESP) in Eagle's syndrome.

Article	Year
Hydrogen-rich saline may be an effective and specific novel treatment for osteoradionecrosis of the jaw. Therapeutics and clinical risk management\| PubMed ID: 26508867	2015
Application of surgical navigation in styloidectomy for treating Eagle's syndrome. Therapeutics and clinical risk management\| PubMed ID: 27110119	2016

Yuanli Chen

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