Catherine Verfaillie

Department of Development and Regeneration, KU Leuven

Affiliated withKU Leuven

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2022

Other Publications

Article	Year
Human pluripotent stem cell-derived hepatocytes support complete replication of hepatitis C virus. Journal of hepatology\| PubMed ID: 22521345	2012
Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion. Development (Cambridge, England)\| PubMed ID: 22912414	2012
Neural differentiation and support of neuroregeneration of non-neural adult stem cells. Progress in brain research\| PubMed ID: 23186708	2012
A novel role of BMP4 in adult hematopoietic stem and progenitor cell homing via Smad independent regulation of integrin-α4 expression. Blood\| PubMed ID: 23243277	2013
Immunological characteristics of human mesenchymal stem cells and multipotent adult progenitor cells. Immunology and cell biology\| PubMed ID: 23295415	2013
Glypican-3-mediated inhibition of CD26 by TFPI: a novel mechanism in hematopoietic stem cell homing and maintenance. Blood\| PubMed ID: 23327927	2013
COUP-TFII orchestrates venous and lymphatic endothelial identity by homo- or hetero-dimerisation with PROX1. Journal of cell science\| PubMed ID: 23345397	2013
18F-FDG labeling of mesenchymal stem cells and multipotent adult progenitor cells for PET imaging: effects on ultrastructure and differentiation capacity. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 23353687	2013
Self-renewal of neural stem cells: implications for future therapies. Frontiers in physiology\| PubMed ID: 23513073	2013
Mutual interaction between human multipotent adult progenitor cells and NK cells. Cell transplantation\| PubMed ID: 23562064	2014
Mesenchymal stem cells migration homing and tracking. Stem cells international\| PubMed ID: 24194766	2013
Biliary cells to the rescue of Prometheus. Gastroenterology\| PubMed ID: 24462990	2014
Hepatic differentiation of human embryonic stem cells on microcarriers. Journal of biotechnology\| PubMed ID: 24480567	2014
Prospectively isolated NGN3-expressing progenitors from human embryonic stem cells give rise to pancreatic endocrine cells. Stem cells translational medicine\| PubMed ID: 24493854	2014
MicroRNAs: the fine modulators of liver development and function. Liver international : official journal of the International Association for the Study of the Liver\| PubMed ID: 24517588	2014
Optimization of multimodal imaging of mesenchymal stem cells using the human sodium iodide symporter for PET and Cerenkov luminescence imaging. PloS one\| PubMed ID: 24747914	2014
SMAD signaling regulates CXCL12 expression in the bone marrow niche, affecting homing and mobilization of hematopoietic progenitors. Stem cells (Dayton, Ohio)\| PubMed ID: 25069965	2014
FANCA knockout in human embryonic stem cells causes a severe growth disadvantage. Stem cell research\| PubMed ID: 25108529	2014
Controlling and monitoring stem cell safety in vivo in an experimental rodent model. Stem cells (Dayton, Ohio)\| PubMed ID: 25142614	2014
Radiolabeling strategies for radionuclide imaging of stem cells. Stem cell reviews\| PubMed ID: 25534590	2015
Restoration of progranulin expression rescues cortical neuron generation in an induced pluripotent stem cell model of frontotemporal dementia. Stem cell reports\| PubMed ID: 25556567	2015
Contribution of different bone marrow-derived cell types in endometrial regeneration using an irradiated murine model. Fertility and sterility\| PubMed ID: 25813284	2015
Assessment of bystander killing-mediated therapy of malignant brain tumors using a multimodal imaging approach. Stem cell research & therapy\| PubMed ID: 26345383	2015
Altered neuronal network and rescue in a human MECP2 duplication model. Molecular psychiatry\| PubMed ID: 26347316	2016
Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition. Stem cell reports\| PubMed ID: 26455413	2015
Mesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscle. The Journal of clinical investigation\| PubMed ID: 26571398	2015
Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways. Stem cell research\| PubMed ID: 26599326	2015
Sodium Iodide Symporter PET and BLI Noninvasively Reveal Mesoangioblast Survival in Dystrophic Mice. Stem cell reports\| PubMed ID: 26626179	2015
Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication. Journal of hepatology\| PubMed ID: 26626494	2016
Monitoring the Bystander Killing Effect of Human Multipotent Stem Cells for Treatment of Malignant Brain Tumors. Stem cells international\| PubMed ID: 26880961	2016
In Vivo Interleukin-13-Primed Macrophages Contribute to Reduced Alloantigen-Specific T Cell Activation and Prolong Immunological Survival of Allogeneic Mesenchymal Stem Cell Implants. Stem cells (Dayton, Ohio)\| PubMed ID: 26992046	2016
Increased Understanding of Stem Cell Behavior in Neurodegenerative and Neuromuscular Disorders by Use of Noninvasive Cell Imaging. Stem cells international\| PubMed ID: 26997958	2016
Neovascularization Potential of Blood Outgrowth Endothelial Cells From Patients With Stable Ischemic Heart Failure Is Preserved. Journal of the American Heart Association\| PubMed ID: 27091182	2016
Pancreatic differentiation of Pdx1-GFP reporter mouse induced pluripotent stem cells. Differentiation; research in biological diversity\| PubMed ID: 27181524	2016
Epigenetic Induction of Definitive and Pancreatic Endoderm Cell Fate in Human Fibroblasts. Stem cells international\| PubMed ID: 27403168	2016
Clinical-Grade Human Multipotent Adult Progenitor Cells Block CD8+ Cytotoxic T Lymphocytes. Stem cells translational medicine\| PubMed ID: 27465071	2016
H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In Vitro. Stem cell reports\| PubMed ID: 27477635	2016
Cell Expansion During Directed Differentiation of Stem Cells Toward the Hepatic Lineage. Stem cells and development\| PubMed ID: 27806669	2017
De novo design of a biologically active amyloid. Science (New York, N.Y.)\| PubMed ID: 27846578	2016
Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors. Metabolic engineering\| PubMed ID: 27847310	2017
Outside-in integrin signalling regulates haematopoietic stem cell function via Periostin-Itgav axis. Nature communications\| PubMed ID: 27905395	2016
Distinct Molecular Signature of Murine Fetal Liver and Adult Hematopoietic Stem Cells Identify Novel Regulators of Hematopoietic Stem Cell Function. Stem cells and development\| PubMed ID: 27958775	2017
PDGFRα Cells in Embryonic Stem Cell Cultures Represent the In Vitro Equivalent of the Pre-implantation Primitive Endoderm Precursors. Stem cell reports\| PubMed ID: 28089671	2017
Epithelial organoid cultures from patients with ulcerative colitis and Crohn's disease: a truly long-term model to study the molecular basis for inflammatory bowel disease? Gut\| PubMed ID: 28159838	2017
Activin A Modulates CRIPTO-1/HNF4 Cells to Guide Cardiac Differentiation from Human Embryonic Stem Cells. Stem cells international\| PubMed ID: 28163723	2017
Hmga2 translocation induced in skin tumorigenesis. Oncotarget\| PubMed ID: 28415789	2017
Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells. Nature communications\| PubMed ID: 28492237	2017
Multipotent adult progenitor cells improve the hematopoietic function in myelodysplasia. Cytotherapy\| PubMed ID: 28499585	2017
Molecular Imaging of Human Embryonic Stem Cells Stably Expressing Human PET Reporter Genes After Zinc Finger Nuclease-Mediated Genome Editing. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 28596158	2017
Immunoregulatory effects of multipotent adult progenitor cells in a porcine ex vivo lung perfusion model. Stem cell research & therapy\| PubMed ID: 28676074	2017
Replication of the Zika virus in different iPSC-derived neuronal cells and implications to assess efficacy of antivirals. Antiviral research\| PubMed ID: 28736077	2017
HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients. Nature communications\| PubMed ID: 29021520	2017
Dynamic regulation of EZH2 from HPSc to hepatocyte-like cell fate. PloS one\| PubMed ID: 29091973	2017
Human intestinal epithelium in a dish: Current models for research into gastrointestinal pathophysiology. United European gastroenterology journal\| PubMed ID: 29238585	2017
SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells. Stem cell reports\| PubMed ID: 29337119	2018
Generating tissue-resident macrophages from pluripotent stem cells: Lessons learned from microglia. Cellular immunology\| PubMed ID: 29433896	2018
Folic Acid Exposure Rescues Spina Bifida Aperta Phenotypes in Human Induced Pluripotent Stem Cell Model. Scientific reports\| PubMed ID: 29440666	2018
PFN2 and GAMT as common molecular determinants of axonal Charcot-Marie-Tooth disease. Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 29449460	2018
Multipotent Adult Progenitor Cells Support Lymphatic Regeneration at Multiple Anatomical Levels during Wound Healing and Lymphedema. Scientific reports\| PubMed ID: 29497054	2018
Recent advances in lineage differentiation from stem cells: hurdles and opportunities? F1000Research\| PubMed ID: 29552337	2018
Strategies for In Vivo Genome Editing in Nondividing Cells. Trends in biotechnology\| PubMed ID: 29685818	2018
Generation of hepatocyte- and endocrine pancreatic-like cells from human induced endodermal progenitor cells. PloS one\| PubMed ID: 29750821	2018
The human somatostatin receptor type 2 as an imaging and suicide reporter gene for pluripotent stem cell-derived therapy of myocardial infarction. Theranostics\| PubMed ID: 29774076	2018
In Vitro Pluripotent Stem Cell Differentiation to Hepatocyte Ceases Further Maturation at an Equivalent Stage of E15 in Mouse Embryonic Liver Development. Stem cells and development\| PubMed ID: 29851366	2018
Energy Producing Metabolic Pathways in Functional Regulation of the Hematopoietic Stem Cells. IUBMB life\| PubMed ID: 29999238	2018
Generation of a human induced pluripotent stem cell-based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neuro... Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 30036493	2018
Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis. Cell stem cell\| PubMed ID: 30049452	2018
Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2. Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 30442540	2019
The Impact of Integrin β2 on Granulocyte/Macrophage Progenitor Proliferation. Stem cells (Dayton, Ohio)\| PubMed ID: 30537419	2019
Human stem cell-derived hepatocyte-like cells support Zika virus replication and provide a relevant model to assess the efficacy of potential antivirals. PloS one\| PubMed ID: 30566505	2018
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity. Nature\| PubMed ID: 30728499	2019
Breast cancer cells rely on environmental pyruvate to shape the metastatic niche. Nature\| PubMed ID: 30814728	2019
Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA. Cell reports\| PubMed ID: 30917309	2019
Dystrophin deficiency leads to dysfunctional glutamate clearance in iPSC derived astrocytes. Translational psychiatry\| PubMed ID: 31434868	2019
Carfilzomib-induced reticulocytosis in patients with multiple myeloma is caused by impaired terminal erythroid maturation. Leukemia\| PubMed ID: 31467428	2020
Differentiation but not ALS mutations in FUS rewires motor neuron metabolism. Nature communications\| PubMed ID: 31515480
Stem-cell-derived human microglia transplanted in mouse brain to study human disease. Nature neuroscience\| PubMed ID: 31659342	2019
Integrative and perturbation-based analysis of the transcriptional dynamics of TGFβ/BMP system components in transition from embryonic stem cells to neural progenitors. Stem cells (Dayton, Ohio)\| PubMed ID: 31675135	2020
Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease. Archives of toxicology\| PubMed ID: 31919559	2020
Functional expression and pharmacological modulation of TRPM3 in human sensory neurons. British journal of pharmacology\| PubMed ID: 31985045	2020
Unraveling the transcriptional determinants of liver sinusoidal endothelial cell specialization. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 32116021	2020
Alternative Cell Sources for Liver Parenchyma Repopulation: Where Do We Stand? Cells\| PubMed ID: 32121068	2020
Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines. Nature communications\| PubMed ID: 32170132	2020
Corrigendum to "FANCA knockout in human embryonic stem cells causes a severe growth disadvantage" [Stem Cell Res.13/2 (2014) 240-50]. Stem cell research\| PubMed ID: 32199280	2020
Ex Vivo Mimicking of Inflammation in Organoids Derived From Patients With Ulcerative Colitis. Gastroenterology\| PubMed ID: 32474118	2020
Gene editing technology for improving life quality: A dream coming true? Clinical genetics\| PubMed ID: 32506418	2021
The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods. Archives of toxicology\| PubMed ID: 32632539	2020
The Periostin/Integrin-αv Axis Regulates the Size of Hematopoietic Stem Cell Pool in the Fetal Liver. Stem cell reports\| PubMed ID: 32735820	2020
Correction of CFTR function in intestinal organoids to guide treatment of cystic fibrosis. The European respiratory journal\| PubMed ID: 32747394	2021
Towards Mimicking the Fetal Liver Niche: The Influence of Elasticity and Oxygen Tension on Hematopoietic Stem/Progenitor Cells Cultured in 3D Fibrin Hydrogels. International journal of molecular sciences\| PubMed ID: 32887387	2020
Generation of oligodendrocytes and establishment of an all-human myelinating platform from human pluripotent stem cells. Nature protocols\| PubMed ID: 33097924	2020
Comparing in vitro human liver models to in vivo human liver using RNA-Seq. Archives of toxicology\| PubMed ID: 33106934	2021
Therapeutic modalities and novel approaches in regenerative medicine for COVID-19. International journal of antimicrobial agents\| PubMed ID: 33213829	2020
PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells. Cell death & disease\| PubMed ID: 33446637	2021
Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes. Toxicology in vitro : an international journal published in association with BIBRA\| PubMed ID: 33545341	2021
Niche-Mediated Integrin Signaling Supports Steady-State Hematopoiesis in the Spleen. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 33637617	2021
HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations. The EMBO journal\| PubMed ID: 33694180	2021
-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility. Science advances\| PubMed ID: 33837088	2021
Rectal organoid morphology analysis (ROMA) as a promising diagnostic tool in cystic fibrosis. Thorax\| PubMed ID: 33859053	2021
Directed differentiation of human induced pluripotent stem cells to hepatic stellate cells. Nature protocols\| PubMed ID: 33864055	2021
SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System. Stem cell reviews and reports\| PubMed ID: 33982246	2021
Actuation enhances patterning in human neural tube organoids. Nature communications\| PubMed ID: 34045434	2021
A fully defined matrix to support a pluripotent stem cell derived multi-cell-liver steatohepatitis and fibrosis model. Biomaterials\| PubMed ID: 34304139	2021
MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System. Cells\| PubMed ID: 34359839	2021
Tweaking Progranulin Expression: Therapeutic Avenues and Opportunities. Frontiers in molecular neuroscience\| PubMed ID: 34366786	2021
Doxycycline inducible overexpression systems: how to induce your gene of interest without inducing misinterpretations. Molecular biology of the cell\| PubMed ID: 34383558	2021
Fast and Efficient Generation of Isogenic Induced Pluripotent Stem Cell Lines Using Adenine Base Editing. The CRISPR journal\| PubMed ID: 34406036	2021
Fetal hematopoietic stem cell homing is controlled by VEGF regulating the integrity and oxidative status of the stromal-vascular bone marrow niches. Cell reports\| PubMed ID: 34433017	2021
Fluorescent tagging of endogenous Heme oxygenase-1 in human induced pluripotent stem cells for high content imaging of oxidative stress in various differentiated lineages. Archives of toxicology\| PubMed ID: 34480604	2021
Organoid and microfluidics-based platforms for drug screening in COVID-19. Drug discovery today\| PubMed ID: 34954328	2022
A Novel UPLC-MS Metabolomic Analysis-Based Strategy to Monitor the Course and Extent of iPSC Differentiation to Hepatocytes. Journal of proteome research\| PubMed ID: 34982937	2022
HiPSC-Derived Hepatocyte-like Cells Can Be Used as a Model for Transcriptomics-Based Study of Chemical Toxicity. Toxics\| PubMed ID: 35051043	2021
Human iPSC model reveals a central role for NOX4 and oxidative stress in Duchenne cardiomyopathy. Stem cell reports\| PubMed ID: 35090586	2022
Current Status and Challenges of Human Induced Pluripotent Stem Cell-Derived Liver Models in Drug Discovery. Cells\| PubMed ID: 35159250	2022
An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat. Toxicology in vitro : an international journal published in association with BIBRA\| PubMed ID: 35182771	2022
Metabolically Improved Stem Cell Derived Hepatocyte-Like Cells Support HBV Life Cycle and Are a Promising Tool for HBV Studies and Antiviral Drug Screenings. Biomedicines\| PubMed ID: 35203482	2022
Engineering neurovascular organoids with 3D printed microfluidic chips. Lab on a chip\| PubMed ID: 35333271	2022