George Daley

Childrens Hospital, Harvard Medical School

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 8	2007

Other Publications

Article	Year
Critical role for cyclin D2 in BCR/ABL-induced proliferation of hematopoietic cells. Cancer research\| PubMed ID: 11809706	2002
A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence. Nature cell biology\| PubMed ID: 11812999	2002
A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling. Genes & development\| PubMed ID: 11914273	2002
Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems. Biotechnology and bioengineering\| PubMed ID: 11948451	2002
Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy. Cell\| PubMed ID: 11955443	2002
HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell\| PubMed ID: 11955444	2002
Overcoming STI571 resistance with the farnesyl transferase inhibitor SCH66336. Blood\| PubMed ID: 12130526	2002
Prospects for stem cell therapeutics: myths and medicines. Current opinion in genetics & development\| PubMed ID: 12200167	2002
Novel retroviral vectors to facilitate expression screens in mammalian cells. Nucleic acids research\| PubMed ID: 12490733	2002
Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL. Cell\| PubMed ID: 12654249	2003
Dodging the magic bullet: understanding imatinib resistance. Cancer biology & therapy\| PubMed ID: 12673130	2003
Gleevec resistance: lessons for target-directed drug development. Cell cycle (Georgetown, Tex.)\| PubMed ID: 12734421	2003
A role for thrombopoietin in hemangioblast development. Stem cells (Dayton, Ohio)\| PubMed ID: 12743322	2003
Towards combination target-directed chemotherapy for chronic myeloid leukemia: role of farnesyl transferase inhibitors. Seminars in hematology\| PubMed ID: 12783369	2003
From embryos to embryoid bodies: generating blood from embryonic stem cells. Annals of the New York Academy of Sciences\| PubMed ID: 12799290	2003
ES cells prove egg-straordinary. Nature biotechnology\| PubMed ID: 12833097	2003
Cloning and stem cells--handicapping the political and scientific debates. The New England journal of medicine\| PubMed ID: 12867604	2003
Enhanced hematopoietic differentiation of embryonic stem cells conditionally expressing Stat5. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12930895	2003
cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes. Nature\| PubMed ID: 13679919	2003
Hematopoiesis from embryonic stem cells: lessons from and for ontogeny. Experimental hematology\| PubMed ID: 14585361	2003
A screen to identify drug resistant variants to target-directed anti-cancer agents. Biological procedures online\| PubMed ID: 14615817	2003
Realistic prospects for stem cell therapeutics. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program\| PubMed ID: 14633792	2003
Genetic complementation of cytokine signaling identifies central role of kinases in hematopoietic cell proliferation. Oncogene\| PubMed ID: 14647454	2004
Derivation of embryonic germ cells and male gametes from embryonic stem cells. Nature\| PubMed ID: 14668819	2004
Mechanisms and implications of imatinib resistance mutations in BCR-ABL. Current opinion in hematology\| PubMed ID: 14676625	2004
Development of hematopoietic repopulating cells from embryonic stem cells. Methods in enzymology\| PubMed ID: 14696341	2003
小鼠胚胎干细胞自我更新与分化信号转导多元蛋白质&#x7EC... Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14978270	2004
Taking stock and planning for the next decade: realistic prospects for stem cell therapies for the nervous system. Journal of neuroscience research\| PubMed ID: 15048913	2004
A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth. Oncogene\| PubMed ID: 15064711	2004
Origins of mammalian hematopoiesis: in vivo paradigms and in vitro models. Current topics in developmental biology\| PubMed ID: 15094298	2004
Nuclear transplantation, embryonic stem cells and the potential for cell therapy. The hematology journal : the official journal of the European Haematology Association / EHA\| PubMed ID: 15190291	2004
Alchemy in the liver: fact or fusion? Nature medicine\| PubMed ID: 15229507	2004
Missed opportunities in embryonic stem-cell research. The New England journal of medicine\| PubMed ID: 15302910	2004
LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 15342941	2004
Bayesian analysis of signaling networks governing embryonic stem cell fate decisions. Bioinformatics (Oxford, England)\| PubMed ID: 15479714	2005
Inducible transgene expression in mouse stem cells. Methods in molecular medicine\| PubMed ID: 15492386	2005
Chronic myeloid leukemia: proving ground for cancer stem cells. Cell\| PubMed ID: 15507204	2004
In vitro gametogenesis from embryonic stem cells. Current opinion in cell biology\| PubMed ID: 15530782	2004
Altered nuclear transfer in stem-cell research - a flawed proposal. The New England journal of medicine\| PubMed ID: 15625329	2004
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl. Cancer cell\| PubMed ID: 15710326	2005
The homeobox gene HEX regulates proliferation and differentiation of hemangioblasts and endothelial cells during ES cell differentiation. Blood\| PubMed ID: 15728128	2005
Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation. Oncogene\| PubMed ID: 15735728	2005
High-efficiency RNA interference in human embryonic stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 15749924	2005
Stem cell research: science, ethics and policy. Medical ethics (Burlington, Mass.)\| PubMed ID: 15856604	2005
Customized human embryonic stem cells. Nature biotechnology\| PubMed ID: 16003368	2005
Patterning definitive hematopoietic stem cells from embryonic stem cells. Experimental hematology\| PubMed ID: 16140144	2005
Therapeutic potential of embryonic stem cells. Blood reviews\| PubMed ID: 16275420	2005
Scientific and clinical opportunities for modeling blood disorders with embryonic stem cells. Blood\| PubMed ID: 16332966	2006
Pilot study of lonafarnib, a farnesyl transferase inhibitor, in patients with chronic myeloid leukemia in the chronic or accelerated phase that is resistant or refractory to imatinib therapy... Cancer\| PubMed ID: 16342165	2006
Novel role for PDEF in epithelial cell migration and invasion. Cancer research\| PubMed ID: 16357167	2005
Embryonic stem cell-derived hematopoietic stem cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16357205	2005
Acceleration of mesoderm development and expansion of hematopoietic progenitors in differentiating ES cells by the mouse Mix-like homeodomain transcription factor. Blood\| PubMed ID: 16403910	2006
Anticipating clinical resistance to target-directed agents : the BCR-ABL paradigm. Molecular diagnosis & therapy\| PubMed ID: 16669605	2006
Activity of dual SRC-ABL inhibitors highlights the role of BCR/ABL kinase dynamics in drug resistance. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16754879	2006
Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17068127	2006
Male germ cells. Methods in enzymology\| PubMed ID: 17141043	2006
Transgene expression and RNA interference in embryonic stem cells. Methods in enzymology\| PubMed ID: 17161693	2006
Histocompatible embryonic stem cells by parthenogenesis. Science (New York, N.Y.)\| PubMed ID: 17170255	2007
Ethics. The ISSCR guidelines for human embryonic stem cell research. Science (New York, N.Y.)\| PubMed ID: 17272706	2007
The cdx-hox pathway in hematopoietic stem cell formation from embryonic stem cells. Annals of the New York Academy of Sciences\| PubMed ID: 17303828	2007
Differentiation potential of histocompatible parthenogenetic embryonic stem cells. Annals of the New York Academy of Sciences\| PubMed ID: 17360798	2007
The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. Blood\| PubMed ID: 17392504	2007
Gametes from embryonic stem cells: a cup half empty or half full? Science (New York, N.Y.)\| PubMed ID: 17446394	2007
In vitro generation of germ cells from murine embryonic stem cells. Nature protocols\| PubMed ID: 17487192	2006
Towards hematopoietic reconstitution from embryonic stem cells: a sanguine future. Current opinion in hematology\| PubMed ID: 17534159	2007
Farnesyl transferase inhibitor resistance probed by target mutagenesis. Blood\| PubMed ID: 17536018	2007
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature\| PubMed ID: 17581586	2007
Human embryonic stem cells flock together. Nature biotechnology\| PubMed ID: 17621300	2007
Phase 1 study of lonafarnib (SCH 66336) and imatinib mesylate in patients with chronic myeloid leukemia who have failed prior single-agent therapy with imatinib. Cancer\| PubMed ID: 17623836	2007
Hemogenic endothelial progenitor cells isolated from human umbilical cord blood. Stem cells (Dayton, Ohio)\| PubMed ID: 17641248	2007
Debugging cellular reprogramming. Nature cell biology\| PubMed ID: 17671453	2007
Current prospects for the generation of patient-specific pluripotent cells from adult tissues. Regenerative medicine\| PubMed ID: 17907926	2007
Towards the generation of patient-specific pluripotent stem cells for combined gene and cell therapy of hematologic disorders. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program\| PubMed ID: 18024604	2007
Reprogramming of human somatic cells to pluripotency with defined factors. Nature\| PubMed ID: 18157115	2008
Human embryonic stem cell derivation from poor-quality embryos. Nature biotechnology\| PubMed ID: 18223642	2008
Enhanced plating efficiency of trypsin-adapted human embryonic stem cells is reversible and independent of trisomy 12/17. Cloning and stem cells\| PubMed ID: 18241122	2008
Modulation of murine embryonic stem cell-derived CD41+c-kit+ hematopoietic progenitors by ectopic expression of Cdx genes. Blood\| PubMed ID: 18252864	2008
Selective blockade of microRNA processing by Lin28. Science (New York, N.Y.)\| PubMed ID: 18292307	2008
Prospects for stem cell-based therapy. Cell\| PubMed ID: 18295571	2008
Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome. The Journal of clinical investigation\| PubMed ID: 18324336	2008
Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera. Cell stem cell\| PubMed ID: 18371359	2007
Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer. Cell stem cell\| PubMed ID: 18371368	2007
BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway. Cell stem cell\| PubMed ID: 18371423	2008
Derivation and maintenance of human embryonic stem cells from poor-quality in vitro fertilization embryos. Nature protocols\| PubMed ID: 18451800	2008
Cdx gene deficiency compromises embryonic hematopoiesis in the mouse. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18511567	2008
Ras-MAPK signaling promotes trophectoderm formation from embryonic stem cells and mouse embryos. Nature genetics\| PubMed ID: 18536715	2008
Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. The Journal of biological chemistry\| PubMed ID: 18550544	2008
Generation of human-induced pluripotent stem cells. Nature protocols\| PubMed ID: 18600223	2008
Molecular basis of pluripotency. Human molecular genetics\| PubMed ID: 18632692	2008
From fibroblasts to iPS cells: induced pluripotency by defined factors. Journal of cellular biochemistry\| PubMed ID: 18668528	2008
Disease-specific induced pluripotent stem cells. Cell\| PubMed ID: 18691744	2008
Isolation of hematopoietic stem cells from mouse embryonic stem cells. Current protocols in stem cell biology\| PubMed ID: 18770632	2008
Activation of tyrosine kinases by mutation of the gatekeeper threonine. Nature structural & molecular biology\| PubMed ID: 18794843	2008
Mesodermal patterning activity of SCL. Experimental hematology\| PubMed ID: 18809240	2008
New ISSCR guidelines underscore major principles for responsible translational stem cell research. Cell stem cell\| PubMed ID: 19041777	2008
Efficient gene knockdowns in human embryonic stem cells using lentiviral-based RNAi. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19089348	2009
Human iPS cell derivation/reprogramming. Current protocols in stem cell biology\| PubMed ID: 19170021	2009
ICSBP-mediated immune protection against BCR-ABL-induced leukemia requires the CCL6 and CCL9 chemokines. Blood\| PubMed ID: 19171873	2009
Broader implications of defining standards for the pluripotency of iPSCs. Cell stem cell\| PubMed ID: 19265657	2009
Generation of induced pluripotent stem cells from human blood. Blood\| PubMed ID: 19299331	2009
Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell\| PubMed ID: 19303855	2009
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nature biotechnology\| PubMed ID: 19329998	2009
Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nature biotechnology\| PubMed ID: 19330000	2009
Upping the ante: recent advances in direct reprogramming. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 19337233	2009
Functional evidence that the self-renewal gene NANOG regulates human tumor development. Stem cells (Dayton, Ohio)\| PubMed ID: 19415763	2009
Surface antigen phenotypes of hematopoietic stem cells from embryos and murine embryonic stem cells. Blood\| PubMed ID: 19420357	2009
Biomechanical forces promote embryonic haematopoiesis. Nature\| PubMed ID: 19440194	2009
Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1. Nature\| PubMed ID: 19458618	2009
Lin28 promotes transformation and is associated with advanced human malignancies. Nature genetics\| PubMed ID: 19483683	2009
Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment. Nature\| PubMed ID: 19516257	2009
Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell stem cell\| PubMed ID: 19540188	2009
Balancing work and life: a conversation with George Daley. Interviewed by Majlinda Lako and Susan Daher. Stem cells (Dayton, Ohio)\| PubMed ID: 19544404	2009
Cross-regulation of the Nanog and Cdx2 promoters. Cell research\| PubMed ID: 19564890	2009
9-(Arenethenyl)purines as dual Src/Abl kinase inhibitors targeting the inactive conformation: design, synthesis, and biological evaluation. Journal of medicinal chemistry\| PubMed ID: 19572547	2009
A role for Lin28 in primordial germ-cell development and germ-cell malignancy. Nature\| PubMed ID: 19578360	2009
microRNA expression during trophectoderm specification. PloS one\| PubMed ID: 19582159	2009
Disease models from pluripotent stem cells. Annals of the New York Academy of Sciences\| PubMed ID: 19796247	2009
Hematopoietic development from human induced pluripotent stem cells. Annals of the New York Academy of Sciences\| PubMed ID: 19796250	2009
Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells. Nature biotechnology\| PubMed ID: 19826408	2009
Generation of functional human hepatic endoderm from human induced pluripotent stem cells. Hepatology (Baltimore, Md.)\| PubMed ID: 19877180	2010
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nature genetics\| PubMed ID: 19881528	2009
Autologous blood cell therapies from pluripotent stem cells. Blood reviews\| PubMed ID: 19910091	2010
A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells. PLoS genetics\| PubMed ID: 19911041	2009
Application of induced pluripotent stem cells to hematologic disease. Cytotherapy\| PubMed ID: 19929461	2009
AP24163 inhibits the gatekeeper mutant of BCR-ABL and suppresses in vitro resistance. Chemical biology & drug design\| PubMed ID: 20028401	2010
Stem cells: roadmap to the clinic. The Journal of clinical investigation\| PubMed ID: 20051631	2010
Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors. Nature\| PubMed ID: 20072125	2010
Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage. Blood\| PubMed ID: 20089964	2010
Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients. Nature\| PubMed ID: 20164838	2010
Lin28: A microRNA regulator with a macro role. Cell\| PubMed ID: 20178735	2010
AID for reprogramming. Cell research\| PubMed ID: 20190775	2010
Robust enhancement of neural differentiation from human ES and iPS cells regardless of their innate difference in differentiation propensity. Stem cell reviews\| PubMed ID: 20376579	2010
Interaction of retinoic acid and scl controls primitive blood development. Blood\| PubMed ID: 20410509	2010
Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. Cell stem cell\| PubMed ID: 20452313	2010
Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis. Haematologica\| PubMed ID: 20494928	2010
Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies. Nature genetics\| PubMed ID: 20512147	2010
Straight talk with...George Daley. Interview by Elie Dolgin. Nature medicine\| PubMed ID: 20526308	2010
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. Nature medicine\| PubMed ID: 20616797	2010
Reprogramming of T cells from human peripheral blood. Cell stem cell\| PubMed ID: 20621044	2010
Molecular basis of the first cell fate determination in mouse embryogenesis. Cell research\| PubMed ID: 20628366	2010
All-trans retinoic acid directs urothelial specification of murine embryonic stem cells via GATA4/6 signaling mechanisms. PloS one\| PubMed ID: 20644631	2010
Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature\| PubMed ID: 20720541	2010
Clump passaging and expansion of human embryonic and induced pluripotent stem cells on mouse embryonic fibroblast feeder cells. Current protocols in stem cell biology\| PubMed ID: 20814935	2010
Dynamic instability of genomic methylation patterns in pluripotent stem cells. Epigenetics & chromatin\| PubMed ID: 20868487	2010
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell stem cell\| PubMed ID: 20888316	2010
Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome). Blood\| PubMed ID: 21037085	2011
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells. Nature genetics\| PubMed ID: 21057500	2010
Another horse in the meta-stable state of pluripotency. Cell stem cell\| PubMed ID: 21112555	2010
MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states. Cell stem cell\| PubMed ID: 21112562	2010
Induced pluripotent stem cells: a novel frontier in the study of human primary immunodeficiencies. The Journal of allergy and clinical immunology\| PubMed ID: 21185069	2011
Cellular therapy for fanconi anemia: the past, present, and future. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 21195298	2011
Stage-specific signaling through TGFÎ² family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells. Development (Cambridge, England)\| PubMed ID: 21270052	2011
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell stem cell\| PubMed ID: 21295276	2011
Somatic coding mutations in human induced pluripotent stem cells. Nature\| PubMed ID: 21368825	2011
Investigating monogenic and complex diseases with pluripotent stem cells. Nature reviews. Genetics\| PubMed ID: 21386866	2011
Interactions between Cdx genes and retinoic acid modulate early cardiogenesis. Developmental biology\| PubMed ID: 21466798	2011
Induced pluripotent stem cells for neural tissue engineering. Biomaterials\| PubMed ID: 21514663	2011
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature\| PubMed ID: 21552279	2011
Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice. PloS one\| PubMed ID: 21559507	2011
The nomenclature system should be sustainable, but also practical. Cell stem cell\| PubMed ID: 21624802	2011
microRNAs become macro players in somatic cell reprogramming. Genome medicine\| PubMed ID: 21699744	2011
Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients. Annals of neurology\| PubMed ID: 21721033	2011
Induced pluripotent stem cells for modelling human diseases. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 21727133	2011
From Hen House to Bedside: Tracing Hanafusa's Legacy from Avian Leukemia Viruses to SRC to ABL and Beyond. Genes & cancer\| PubMed ID: 21779439	2010
Telomere dynamics in dyskeratosis congenita: the long and the short of iPS. Cell research\| PubMed ID: 21788988	2011
Genomic approaches to deconstruct pluripotency. Annual review of genomics and human genetics\| PubMed ID: 21801025	2011
Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival. Cell\| PubMed ID: 21854985	2011
Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity. Nature cell biology\| PubMed ID: 21909099	2011
The Lin28/let-7 axis regulates glucose metabolism. Cell\| PubMed ID: 21962509	2011
Stem cells: Triple genomes go far. Nature\| PubMed ID: 21979039	2011
Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration. Cell\| PubMed ID: 22036566	2011
Induced pluripotent stem cells--opportunities for disease modelling and drug discovery. Nature reviews. Drug discovery\| PubMed ID: 22076509	2011
Cell cycle adaptations of embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22084091	2011
Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells. Nature biotechnology\| PubMed ID: 22119740	2011
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nature biotechnology\| PubMed ID: 22119741	2011
Live-cell immunofluorescence staining of human pluripotent stem cells. Current protocols in stem cell biology\| PubMed ID: 22135082	2011
Polycomb repressive complex 2 regulates normal development of the mouse heart. Circulation research\| PubMed ID: 22158708	2012
The promise of induced pluripotent stem cells in research and therapy. Nature\| PubMed ID: 22258608	2012
Derivation of human embryonic stem cells with NEMO deficiency. Stem cell research\| PubMed ID: 22284529	2012
Overcoming Reprogramming Resistance of Fanconi Anemia Cells. Blood\| PubMed ID: 22371882	2012
Chromatin-modifying enzymes as modulators of reprogramming. Nature\| PubMed ID: 22388813	2012
Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. Developmental cell\| PubMed ID: 22421047	2012
Reprogramming cellular identity for regenerative medicine. Cell\| PubMed ID: 22424223	2012
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22451909	2012
Accessing naïve human pluripotency. Current opinion in genetics & development\| PubMed ID: 22463982	2012
Pluripotent stem cells in research and treatment of hemoglobinopathies. Cold Spring Harbor perspectives in medicine\| PubMed ID: 22474618	2012
Excision of a viral reprogramming cassette by delivery of synthetic Cre mRNA. Current protocols in stem cell biology\| PubMed ID: 22605648	2012
Neuronal properties, in vivo effects, and pathology of a Huntington's disease patient-derived induced pluripotent stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 22628015	2012
Stem cells assessed. Nature reviews. Molecular cell biology\| PubMed ID: 22678486	2012
Quantitative proteomic analysis of induced pluripotent stem cells derived from a human Huntington's disease patient. The Biochemical journal\| PubMed ID: 22694310	2012
The promise and perils of stem cell therapeutics. Cell stem cell\| PubMed ID: 22704514	2012
New lessons learned from disease modeling with induced pluripotent stem cells. Current opinion in genetics & development\| PubMed ID: 22749051	2012
Caudal genes in blood development and leukemia. Annals of the New York Academy of Sciences\| PubMed ID: 22901255	2012
Functional vascular smooth muscle cells derived from human induced pluripotent stem cells via mesenchymal stem cell intermediates. Cardiovascular research\| PubMed ID: 22941255	2012
Therapeutic potential of human induced pluripotent stem cells in experimental stroke. Cell transplantation\| PubMed ID: 23044029	2013
Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23045682	2012
Euchromatin islands in large heterochromatin domains are enriched for CTCF binding and differentially DNA-methylated regions. BMC genomics\| PubMed ID: 23102236	2012
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells. Nature\| PubMed ID: 23103873	2012
Influence of threonine metabolism on S-adenosylmethionine and histone methylation. Science (New York, N.Y.)\| PubMed ID: 23118012	2013
Metabolic regulation in pluripotent stem cells during reprogramming and self-renewal. Cell stem cell\| PubMed ID: 23122286	2012
The transcriptional landscape of hematopoietic stem cell ontogeny. Cell stem cell\| PubMed ID: 23122293	2012
Zcchc11 uridylates mature miRNAs to enhance neonatal IGF-1 expression, growth, and survival. PLoS genetics\| PubMed ID: 23209448	2012
Cellular alchemy and the golden age of reprogramming. Cell\| PubMed ID: 23217698	2012
Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23236128	2013
A blueprint for engineering cell fate: current technologies to reprogram cell identity. Cell research\| PubMed ID: 23277278	2013
Reprogrammed cells for disease modeling and regenerative medicine. Annual review of medicine\| PubMed ID: 23327523	2013
Lin28a Regulates Germ Cell Pool Size and Fertility. Stem cells (Dayton, Ohio)\| PubMed ID: 23378032	2013
Induced pluripotent stem cells with a mitochondrial DNA deletion. Stem cells (Dayton, Ohio)\| PubMed ID: 23400930	2013
The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity. Experimental cell research\| PubMed ID: 23528453	2013
Lin28: primal regulator of growth and metabolism in stem cells. Cell stem cell\| PubMed ID: 23561442	2013
Pluripotent stem cell models of Shwachman-Diamond syndrome reveal a common mechanism for pancreatic and hematopoietic dysfunction. Cell stem cell\| PubMed ID: 23602541	2013
Deciphering the rules of ceRNA networks. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23620514	2013
Regulation of stem cell therapies under attack in Europe: for whom the bell tolls. The EMBO journal\| PubMed ID: 23644381	2013
Fetal deficiency of lin28 programs life-long aberrations in growth and glucose metabolism. Stem cells (Dayton, Ohio)\| PubMed ID: 23666760	2013
Origins and implications of pluripotent stem cell variability and heterogeneity. Nature reviews. Molecular cell biology\| PubMed ID: 23673969	2013
Stem cell metabolism in tissue development and aging. Development (Cambridge, England)\| PubMed ID: 23715547	2013
Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells. Blood\| PubMed ID: 23733337	2013
Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells". Science translational medicine\| PubMed ID: 23740897	2013
A new route to human embryonic stem cells. Nature medicine\| PubMed ID: 23836223	2013
Optimization of scarless human stem cell genome editing. Nucleic acids research\| PubMed ID: 23907390	2013
A chemical logic for reprogramming to pluripotency. Cell research\| PubMed ID: 23979017	2013
Stem cells: Reprogramming in situ. Nature\| PubMed ID: 24025771	2013
Hematopoietic defects and iPSC disease modeling: lessons learned. Immunology letters\| PubMed ID: 24076116	2013
Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell stem cell\| PubMed ID: 24094326	2013
Proteolytic autodigestion: common tissue pathology in Shwachman-Diamond syndrome? Cell cycle (Georgetown, Tex.)\| PubMed ID: 24107623	2013
Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells. Retrovirology\| PubMed ID: 24156636	2013
Development. A stem cell perspective on cellular engineering. Science (New York, N.Y.)\| PubMed ID: 24202165	2013
Lin28 enhances tissue repair by reprogramming cellular metabolism. Cell\| PubMed ID: 24209617	2013
Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity. Molecular cell\| PubMed ID: 24361252	2014
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs. The Journal of experimental medicine\| PubMed ID: 24395885	2014
Lin28 sustains early renal progenitors and induces Wilms tumor. Genes & development\| PubMed ID: 24732380	2014
Functional evaluation of ES-somatic cell hybrids in vitro and in vivo. Cellular reprogramming\| PubMed ID: 24787484	2014
Alternative splicing of MBD2 supports self-renewal in human pluripotent stem cells. Cell stem cell\| PubMed ID: 24813856	2014
Effect of developmental stage of HSC and recipient on transplant outcomes. Developmental cell\| PubMed ID: 24914562	2014
Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models. Cancer cell\| PubMed ID: 25117712	2014
Dissecting engineered cell types and enhancing cell fate conversion via CellNet. Cell\| PubMed ID: 25126792	2014
CellNet: network biology applied to stem cell engineering. Cell\| PubMed ID: 25126793	2014
Stem cell therapy. Use of differentiated pluripotent stem cells as replacement therapy for treating disease. Science (New York, N.Y.)\| PubMed ID: 25146295	2014
The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming. Stem cell reports\| PubMed ID: 25316190	2014
A nontranscriptional role for Oct4 in the regulation of mitotic entry. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25324523	2014
A comparison of non-integrating reprogramming methods. Nature biotechnology\| PubMed ID: 25437882	2015
Deriving blood stem cells from pluripotent stem cells for research and therapy. Best practice & research. Clinical haematology\| PubMed ID: 25455281	2014
Deconstructing transcriptional heterogeneity in pluripotent stem cells. Nature\| PubMed ID: 25471879	2014
Defining cellular identity through network biology. Cell cycle (Georgetown, Tex.)\| PubMed ID: 25485572	2014
Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium. Blood\| PubMed ID: 25587036	2015
Metabolic switches linked to pluripotency and embryonic stem cell differentiation. Cell metabolism\| PubMed ID: 25738450	2015
De novo generation of HSCs from somatic and pluripotent stem cell sources. Blood\| PubMed ID: 25762177	2015
Biotechnology. A prudent path forward for genomic engineering and germline gene modification. Science (New York, N.Y.)\| PubMed ID: 25791083	2015