Stuart M. Haslam

Department of Life Science, Imperial College London

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2022

Other Publications

Article	Year
Protein glycosylation in Parelaphostrongylus tenuis--first description of the Galalpha1-3Gal sequence in a nematode. Glycobiology\| PubMed ID: 16704967	2006
The highly conserved domain of unknown function 1792 has a distinct glycosyltransferase fold. Nature communications\| PubMed ID: 25023666	2014
Murine and human zona pellucida 3 derived from mouse eggs express identical O-glycans. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14673092	2003
Mass spectrometric characterisation of Taenia crassiceps metacestode N-glycans. Molecular and biochemical parasitology\| PubMed ID: 16024105	2005
Differential O-glycosylation of a conserved domain expressed in murine and human ZP3. Biochemistry\| PubMed ID: 16401092	2006
Mass spectrometric analysis of N- and O-glycosylation of tissues and cells. Current opinion in structural biology\| PubMed ID: 16938453	2006
Integrated mass spectrometric strategy for characterizing the glycans from glycosphingolipids and glycoproteins: direct identification of sialyl Le(x) in mice. Glycobiology\| PubMed ID: 17341505	2007
Glycomics analysis of Schistosoma mansoni egg and cercarial secretions. Molecular & cellular proteomics : MCP\| PubMed ID: 17550893	2007
The sperm agglutination antigen-1 (SAGA-1) glycoforms of CD52 are O-glycosylated. Glycobiology\| PubMed ID: 17640971	2007
The GlycanBuilder: a fast, intuitive and flexible software tool for building and displaying glycan structures. Source code for biology and medicine\| PubMed ID: 17683623	2007
GlycoWorkbench: a tool for the computer-assisted annotation of mass spectra of glycans. Journal of proteome research\| PubMed ID: 18311910	2008
Comparative efficacy of neutralizing antibodies elicited by recombinant hemagglutinin proteins from avian H5N1 influenza virus. Journal of virology\| PubMed ID: 18417563	2008
Structural characterisation of neutrophil glycans by ultra sensitive mass spectrometric glycomics methodology. Glycoconjugate journal\| PubMed ID: 18587645	2009
Characterizing the glycome of the mammalian immune system. Immunology and cell biology\| PubMed ID: 18725885	2008
The N-glycolyl form of mouse sialyl Lewis X is recognized by selectins but not by HECA-452 and FH6 antibodies that were raised against human cells. Glycoconjugate journal\| PubMed ID: 19089612	2009
Glycoproteomics: past, present and future. FEBS letters\| PubMed ID: 19328791	2009
Glycosyltransferase function in core 2-type protein O glycosylation. Molecular and cellular biology\| PubMed ID: 19349303	2009
Mass spectrometry in the analysis of N-linked and O-linked glycans. Current opinion in structural biology\| PubMed ID: 19577919	2009
DAS181 inhibits H5N1 influenza virus infection of human lung tissues. Antimicrobial agents and chemotherapy\| PubMed ID: 19596886	2009
Regulated and aberrant glycosylation modulate cardiac electrical signaling. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19666501	2009
Fut2-null mice display an altered glycosylation profile and impaired BabA-mediated Helicobacter pylori adhesion to gastric mucosa. Glycobiology\| PubMed ID: 19706747	2009
Glycomics profiling of Chinese hamster ovary cell glycosylation mutants reveals N-glycans of a novel size and complexity. The Journal of biological chemistry\| PubMed ID: 19951948	2010
Physiological and glycomic characterization of N-acetylglucosaminyltransferase-IVa and -IVb double deficient mice. Glycobiology\| PubMed ID: 20015870	2010
Comparison of methods for profiling O-glycosylation: Human Proteome Organisation Human Disease Glycomics/Proteome Initiative multi-institutional study of IgA1. Molecular & cellular proteomics : MCP\| PubMed ID: 20038609	2010
Mannose receptor interacts with Fc receptors and is critical for the development of crescentic glomerulonephritis in mice. The Journal of clinical investigation\| PubMed ID: 20407205	2010
Glycosylation of {beta}2 subunits regulates GABAA receptor biogenesis and channel gating. The Journal of biological chemistry\| PubMed ID: 20639197	2010
Serum N-glycome biomarker for monitoring development of DENA-induced hepatocellular carcinoma in rat. Molecular cancer\| PubMed ID: 20704698	2010
Glycan analysis and influenza A virus infection of primary swine respiratory epithelial cells: the importance of NeuAc{alpha}2-6 glycans. The Journal of biological chemistry\| PubMed ID: 20724471	2010
Mass spectrometric analysis of mutant mice. Methods in enzymology\| PubMed ID: 20816474	2010
High-sensitivity O-glycomic analysis of mice deficient in core 2 {beta}1,6-N-acetylglucosaminyltransferases. Glycobiology\| PubMed ID: 20855471	2011
The S-layer glycoprotein of the crenarchaeote Sulfolobus acidocaldarius is glycosylated at multiple sites with chitobiose-linked N-glycans. Archaea (Vancouver, B.C.)\| PubMed ID: 20936123	2010
Simian immunodeficiency virus from the sooty mangabey and rhesus macaque is modified with O-linked carbohydrate. Journal of virology\| PubMed ID: 20962077	2011
EUROCarbDB: An open-access platform for glycoinformatics. Glycobiology\| PubMed ID: 21106561	2011
G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction. Glycobiology\| PubMed ID: 21385794	2011
Peracetylated 4-fluoro-glucosamine reduces the content and repertoire of N- and O-glycans without direct incorporation. The Journal of biological chemistry\| PubMed ID: 21493714	2011
Glycomic analysis of human mast cells, eosinophils and basophils. Glycobiology\| PubMed ID: 21725073	2012
Early murine T-lymphocyte activation is accompanied by a switch from N-Glycolyl- to N-acetyl-neuraminic acid and generation of ligands for siglec-E. The Journal of biological chemistry\| PubMed ID: 21835922	2011
Human sperm binding is mediated by the sialyl-Lewis(x) oligosaccharide on the zona pellucida. Science (New York, N.Y.)\| PubMed ID: 21852454	2011
A novel type of macrothrombocytopenia associated with a defect in α2,3-sialylation. The American journal of pathology\| PubMed ID: 21864493	2011
Mannosidase 2, alpha 1 deficiency is associated with ricin resistance in embryonic stem (ES) cells. PloS one\| PubMed ID: 21886775	2011
Histo-blood group antigens act as attachment factors of rabbit hemorrhagic disease virus infection in a virus strain-dependent manner. PLoS pathogens\| PubMed ID: 21901093	2011
Glycosylation of mouse and human immune cells: insights emerging from N-glycomics analyses. Biochemical Society transactions\| PubMed ID: 21936811	2011
Tumor biomarker glycoproteins in the seminal plasma of healthy human males are endogenous ligands for DC-SIGN. Molecular & cellular proteomics : MCP\| PubMed ID: 21986992	2012
The antifungal drug itraconazole inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells. The Journal of biological chemistry\| PubMed ID: 22025615	2011
Sulfoquinovose synthase - an important enzyme in the N-glycosylation pathway of Sulfolobus acidocaldarius. Molecular microbiology\| PubMed ID: 22059775	2011
Glycoproteomic characterization of recombinant mouse α-dystroglycan. Glycobiology\| PubMed ID: 22241827	2012
Loss of effector function of human cytolytic T lymphocytes is accompanied by major alterations in N- and O-glycosylation. The Journal of biological chemistry\| PubMed ID: 22334653	2012
Glycoengineering approach to half-life extension of recombinant biotherapeutics. Bioconjugate chemistry\| PubMed ID: 22681552	2012
The GlycanBuilder and GlycoWorkbench glycoinformatics tools: updates and new developments. Biological chemistry\| PubMed ID: 23109548	2012
Polylactosaminoglycan glycomics: enhancing the detection of high-molecular-weight N-glycans in matrix-assisted laser desorption ionization time-of-flight profiles by matched filtering. Molecular & cellular proteomics : MCP\| PubMed ID: 23325768	2013
The Minimum Information Required for a Glycomics Experiment (MIRAGE) Project: Improving the Standards for Reporting Mass-spectrometry-based Glycoanalytic Data. Molecular & cellular proteomics : MCP\| PubMed ID: 23378518	2013
Glycomic analysis of human respiratory tract tissues and correlation with influenza virus infection. PLoS pathogens\| PubMed ID: 23516363	2013
Competition between core-2 GlcNAc-transferase and ST6GalNAc-transferase regulates the synthesis of the leukocyte selectin ligand on human P-selectin glycoprotein ligand-1. The Journal of biological chemistry\| PubMed ID: 23548905	2013
The use of sialidase therapy for respiratory viral infections. Antiviral research\| PubMed ID: 23602850	2013
Infection of swine ex vivo tissues with avian viruses including H7N9 and correlation with glycomic analysis. Influenza and other respiratory viruses\| PubMed ID: 24001121	2013
Synthesis of biologically active N- and O-linked glycans with multisialylated poly-N-acetyllactosamine extensions using P. damsela α2-6 sialyltransferase. Journal of the American Chemical Society\| PubMed ID: 24256304	2013
Novel expression of Haemonchus contortus vaccine candidate aminopeptidase H11 using the free-living nematode Caenorhabditis elegans. Veterinary research\| PubMed ID: 24289031	2013
Profiling of glycan receptors for minute virus of mice in permissive cell lines towards understanding the mechanism of cell recognition. PloS one\| PubMed ID: 24475195	2014
An in vivo functional screen identifies ST6GalNAc2 sialyltransferase as a breast cancer metastasis suppressor. Cancer discovery\| PubMed ID: 24520024	2014
Towards controlling the glycoform: a model framework linking extracellular metabolites to antibody glycosylation. International journal of molecular sciences\| PubMed ID: 24637934	2014
MIRAGE: the minimum information required for a glycomics experiment. Glycobiology\| PubMed ID: 24653214	2014
Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels. The Journal of allergy and clinical immunology\| PubMed ID: 24698316	2014
Methylated glycans as conserved targets of animal and fungal innate defense. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24879441	2014
JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia. Nature genetics\| PubMed ID: 25129144	2014
Glycomic characterization of respiratory tract tissues of ferrets: implications for its use in influenza virus infection studies. The Journal of biological chemistry\| PubMed ID: 25135641	2014
Systemic blockade of sialylation in mice with a global inhibitor of sialyltransferases. The Journal of biological chemistry\| PubMed ID: 25368325	2014
ST3Gal-4 is the primary sialyltransferase regulating the synthesis of E-, P-, and L-selectin ligands on human myeloid leukocytes. Blood\| PubMed ID: 25498912	2015
Annotation of glycomics MS and MS/MS spectra using the GlycoWorkbench software tool. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 25753699	2015
MKAN27435 is required for the biosynthesis of higher subclasses of lipooligosaccharides in Mycobacterium kansasii. PloS one\| PubMed ID: 25893968	2015
Glycosphingolipid synthesis inhibition limits osteoclast activation and myeloma bone disease. The Journal of clinical investigation\| PubMed ID: 25915583	2015
Gp120 on HIV-1 Virions Lacks O-Linked Carbohydrate. PloS one\| PubMed ID: 25915761	2015
The Cytotoxicity of Elderberry Ribosome-Inactivating Proteins Is Not Solely Determined by Their Protein Translation Inhibition Activity. PloS one\| PubMed ID: 26148207	2015
Enhanced Aromatic Sequons Increase Oligosaccharyltransferase Glycosylation Efficiency and Glycan Homogeneity. Chemistry & biology\| PubMed ID: 26190824	2015
GlyTouCan 1.0--The international glycan structure repository. Nucleic acids research\| PubMed ID: 26476458	2016
XBP1s Links the Unfolded Protein Response to the Molecular Architecture of Mature N-Glycans. Chemistry & biology\| PubMed ID: 26496683	2015
Global N-linked Glycosylation is Not Significantly Impaired in Myoblasts in Congenital Myasthenic Syndromes Caused by Defective Glutamine-Fructose-6-Phosphate Transaminase 1 (GFPT1). Biomolecules\| PubMed ID: 26501342	2015
Cellular O-Glycome Reporter/Amplification to explore O-glycans of living cells. Nature methods\| PubMed ID: 26619014	2016
Bovine Herpesvirus 4 Modulates Its β-1,6-N-Acetylglucosaminyltransferase Activity through Alternative Splicing. Journal of virology\| PubMed ID: 26656682	2016
Glycoproteomic studies of IgE from a novel hyper IgE syndrome linked to PGM3 mutation. Glycoconjugate journal\| PubMed ID: 26687240	2016
Glycosphingolipids on Human Myeloid Cells Stabilize E-Selectin-Dependent Rolling in the Multistep Leukocyte Adhesion Cascade. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 26868209	2016
Evidence for Differential Glycosylation of Trophoblast Cell Types. Molecular & cellular proteomics : MCP\| PubMed ID: 26929217	2016
Characterization of the N-glycans of female Angiostrongylus cantonensis worms. Experimental parasitology\| PubMed ID: 27107931	2016
Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis. eLife\| PubMed ID: 27269286	2016
The human fetoembryonic defense system hypothesis: Twenty years on. Molecular aspects of medicine\| PubMed ID: 27349751	2016
New Helical Binding Domain Mediates a Glycosyltransferase Activity of a Bifunctional Protein. The Journal of biological chemistry\| PubMed ID: 27539847	2016
Mapping the complete glycoproteome of virion-derived HIV-1 gp120 provides insights into broadly neutralizing antibody binding. Scientific reports\| PubMed ID: 27604319	2016
The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets. Glycobiology\| PubMed ID: 27654115	2016
The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data. Glycobiology\| PubMed ID: 27993942	2017
Engineering and Dissecting the Glycosylation Pathway of a Streptococcal Serine-rich Repeat Adhesin. The Journal of biological chemistry\| PubMed ID: 28039332	2016
Partial correction of neutrophil dysfunction by oral galactose therapy in glycogen storage disease type Ib. International immunopharmacology\| PubMed ID: 28126686	2017
Characterization of H type 1 and type 1 -acetyllactosamine glycan epitopes on ovarian cancer specifically recognized by the anti-glycan monoclonal antibody mAb-A4. The Journal of biological chemistry\| PubMed ID: 28167527	2017
The redefinition of Helicobacter pylori lipopolysaccharide O-antigen and core-oligosaccharide domains. PLoS pathogens\| PubMed ID: 28306723	2017
Effects of altered sialic acid biosynthesis on -linked glycan branching and cell surface interactions. The Journal of biological chemistry\| PubMed ID: 28424265	2017
HEK293T cell lines defective for O-linked glycosylation. PloS one\| PubMed ID: 28654657	2017
Insights from the redefinition of lipopolysaccharide O-antigen and core-oligosaccharide domains. Microbial cell (Graz, Austria)\| PubMed ID: 28685143	2017
Human Immunodeficiency Virus and Simian Immunodeficiency Virus Maintain High Levels of Infectivity in the Complete Absence of Mucin-Type O-Glycosylation. Journal of virology\| PubMed ID: 28747495	2017
Towards automation of glycomic profiling of complex biological materials. Glycoconjugate journal\| PubMed ID: 29909447	2018
Photoactivable Glycolipid Antigens Generate Stable Conjugates with CD1d for Invariant Natural Killer T Cell Activation. Bioconjugate chemistry\| PubMed ID: 30085659	2018
Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans. Nature communications\| PubMed ID: 30120234	2018
Loss of GCNT2/I-branched glycans enhances melanoma growth and survival. Nature communications\| PubMed ID: 30135430	2018
XBP1s activation can globally remodel N-glycan structure distribution patterns. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 30305426	2018
The mucinous domain of pancreatic carboxyl-ester lipase (CEL) contains core 1/core 2 glycans that can be modified by ABO blood group determinants. The Journal of biological chemistry\| PubMed ID: 30315106	2018
Thioglycosides Are Efficient Metabolic Decoys of Glycosylation that Reduce Selectin Dependent Leukocyte Adhesion. Cell chemical biology\| PubMed ID: 30344053	2018
Host and viral determinants of influenza A virus species specificity. Nature reviews. Microbiology\| PubMed ID: 30487536	2019
Publisher Correction: Host and viral determinants of influenza A virus species specificity. Nature reviews. Microbiology\| PubMed ID: 30560932	2019
Human B Cell Differentiation Is Characterized by Progressive Remodeling of O-Linked Glycans. Frontiers in immunology\| PubMed ID: 30619255	2018
Serum IgA1 shows increased levels of 2,6-linked sialic acid in breast cancer. Interface focus\| PubMed ID: 30842877	2019
Site-specific glycoproteomic characterization of ES-62: The major secreted product of the parasitic worm Acanthocheilonema viteae. Glycobiology\| PubMed ID: 31094418	2019
East-Asian Helicobacter pylori strains synthesize heptan-deficient lipopolysaccharide. PLoS genetics\| PubMed ID: 31747390	2019
Glycan biomarkers for Alzheimer disease correlate with T-tau and P-tau in cerebrospinal fluid in subjective cognitive impairment. The FEBS journal\| PubMed ID: 31889402	2020
Exteriorisation of Mannoses on Human Erythrocyte Membrane Skeleton Provides 'Eat Me' Signals for Oxidatively Damaged Cells to be Cleared By Macrophages: A Pathway Mediating Hemolysis in Sick... Blood\| PubMed ID: 31909782	2017
Insights into the hyperglycosylation of human chorionic gonadotropin revealed by glycomics analysis. PloS one\| PubMed ID: 32045434	2020
Discovery of O-Linked Carbohydrate on HIV-1 Envelope and Its Role in Shielding against One Category of Broadly Neutralizing Antibodies. Cell reports\| PubMed ID: 32049016	2020
Altered glycosylation of glycodelin in endometrial carcinoma. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 32205858	2020
Glycan characterization of pregnancy-specific glycoprotein 1 and its identification as a novel Galectin-1 ligand. Glycobiology\| PubMed ID: 32280962	2020
Analysis of N- and O-Linked Glycosylation: Differential Glycosylation after Rat Spinal Cord Injury. Journal of neurotrauma\| PubMed ID: 32316850	2020
Role of galectin-glycan circuits in reproduction: from healthy pregnancy to preterm birth (PTB). Seminars in immunopathology\| PubMed ID: 32601855	2020
The glycomic sialylation profile of GNE Myopathy muscle cells does not point to consistent hyposialylation of individual glycoconjugates. Neuromuscular disorders : NMD\| PubMed ID: 32736841	2020
Site-specific characterization of SARS-CoV-2 spike glycoprotein receptor-binding domain. Glycobiology\| PubMed ID: 32886791	2021
Metabolic precision labeling enables selective probing of O-linked -acetylgalactosamine glycosylation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 32989128	2020
Glycosylation of Trypanosoma cruzi TcI antigen reveals recognition by chagasic sera. Scientific reports\| PubMed ID: 33009443	2020
Vulpeculin: a novel and abundant lipocalin in the urine of the common brushtail possum, . Open biology\| PubMed ID: 33022194	2020
Efficient inhibition of O-glycan biosynthesis using the hexosamine analog AcGalNTGc. Cell chemical biology\| PubMed ID: 33609441	2021
Glycoengineering Chinese hamster ovary cells: a short history. Biochemical Society transactions\| PubMed ID: 33704400	2021
Red blood cell mannoses as phagocytic ligands mediating both sickle cell anaemia and malaria resistance. Nature communications\| PubMed ID: 33741926	2021
Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis. Nature communications\| PubMed ID: 33879788	2021
A mutation in SLC37A4 causes a dominantly inherited congenital disorder of glycosylation characterized by liver dysfunction. American journal of human genetics\| PubMed ID: 33964207	2021
Proteome-wide prediction of bacterial carbohydrate-binding proteins as a tool for understanding commensal and pathogen colonisation of the vaginal microbiome. NPJ biofilms and microbiomes\| PubMed ID: 34131152	2021
Major differences in glycosylation and fucosyltransferase expression in low-grade versus high-grade bladder cancer cell lines. Glycobiology\| PubMed ID: 34350945	2021
Rapid Antibody Glycoengineering in CHO Cells Via RNA Interference and CGE-LIF N-Glycomics. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 34611868	2022
Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis. Nature methods\| PubMed ID: 34725484	2021
Author Correction: Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis. Nature methods\| PubMed ID: 34893784	2022
Strategies to control therapeutic antibody glycosylation during bioprocessing: Synthesis and separation. Biotechnology and bioengineering\| PubMed ID: 35182428	2022
Activation of regulatory T cells triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses. Wellcome open research\| PubMed ID: 35224210	2021
Measurement of erythrocyte membrane mannoses to assess splenic function. British journal of haematology\| PubMed ID: 35411940	2022
The Tip of O-Polysaccharide Is a Potent Epitope in Response to Brucellosis Infection and Enables Short Synthetic Antigens to Be Superior Diagnostic Reagents. Microorganisms\| PubMed ID: 35456759	2022