Siiri E. Iismaa

Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute

Affiliated withVictor Chang Cardiac Research Institute University of New South Wales Sydney

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2022

Other Publications

Article	Year
Evolutionary specialization of a tryptophan indole group for transition-state stabilization by eukaryotic transglutaminases. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14566064	2003
Transglutaminase activity is present in highly purified nonsynaptosomal mouse brain and liver mitochondria. Biochemistry\| PubMed ID: 15909997	2005
Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity. The Journal of biological chemistry\| PubMed ID: 16522628	2006
Cross-linking transglutaminases with G protein-coupled receptor signaling. Science's STKE : signal transduction knowledge environment\| PubMed ID: 16985237	2006
Mechanism of allosteric regulation of transglutaminase 2 by GTP. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17179049	2006
Transglutaminases and disease: lessons from genetically engineered mouse models and inherited disorders. Physiological reviews\| PubMed ID: 19584319	2009
Opposing effects of two tissue transglutaminase protein isoforms in neuroblastoma cell differentiation. The Journal of biological chemistry\| PubMed ID: 20007697	2010
Regulation of murine cardiac contractility by activation of α(1A)-adrenergic receptor-operated Ca(2+) entry. Cardiovascular research\| PubMed ID: 21546445	2011
Transglutaminase 2 and its role in pulmonary fibrosis. American journal of respiratory and critical care medicine\| PubMed ID: 21700912	2011
Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22573678	2012
Glucose homeostasis in mice is transglutaminase 2 independent. PloS one\| PubMed ID: 23717413	2013
A proliferative burst during preadolescence establishes the final cardiomyocyte number. Cell\| PubMed ID: 24813607	2014
RhoA/ROCK signaling and pleiotropic α1A-adrenergic receptor regulation of cardiac contractility. PloS one\| PubMed ID: 24919197	2014
Thyroid hormone action in postnatal heart development. Stem cell research\| PubMed ID: 25087894	2014
Irreversible triggers for hypertrophic cardiomyopathy are established in the early postnatal period. Journal of the American College of Cardiology\| PubMed ID: 25677315	2015
Cardiomyocytes Replicate and their Numbers Increase in Young Hearts. Cell\| PubMed ID: 26544928	2015
The prostate-specific protein, transglutaminase 4 (TG4), is an autoantigen associated with male subfertility. Annals of translational medicine\| PubMed ID: 27868003	2016
Cardiac hypertrophy limits infarct expansion after myocardial infarction in mice. Scientific reports\| PubMed ID: 29666426	2018
Targeting transglutaminase 2 partially restores extracellular matrix structure but not alveolar architecture in experimental bronchopulmonary dysplasia. The FEBS journal\| PubMed ID: 29935061	2018
Transglutaminase diseases: from biochemistry to the bedside. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 30593123	2019
Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection. Journal of the American College of Cardiology\| PubMed ID: 30621952	2019
Generation of VCCRIi001-A, a human induced pluripotent stem cell line, from a patient with spontaneous coronary artery dissection. Stem cell research\| PubMed ID: 31707208	2019
Transglutaminase 2 limits the extravasation and the resultant myocardial fibrosis associated with factor XIII-A deficiency. Atherosclerosis\| PubMed ID: 31874419	2020
Transglutaminase 2 Depletion Attenuates α-Synuclein Mediated Toxicity in Mice. Neuroscience\| PubMed ID: 32502569	2020
Spontaneous Coronary Artery Dissection and Fibromuscular Dysplasia: Vasculopathies With a Predilection for Women. Heart, lung & circulation\| PubMed ID: 32713767	2021
Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation. Frontiers in immunology\| PubMed ID: 32793209	2020
Pressure overload by suprarenal aortic constriction in mice leads to left ventricular hypertrophy without c-Kit expression in cardiomyocytes. Scientific reports\| PubMed ID: 32948799	2020
Spontaneous Coronary Artery Dissection: Insights on Rare Genetic Variation From Genome Sequencing. Circulation. Genomic and precision medicine\| PubMed ID: 33125268	2020
DUSP5 expression in left ventricular cardiomyocytes of young hearts regulates thyroid hormone (T3)-induced proliferative ERK1/2 signaling. Scientific reports\| PubMed ID: 33318551	2020
Adaptation to exercise-induced stress is not dependent on cardiomyocyte α-adrenergic receptors. Journal of molecular and cellular cardiology\| PubMed ID: 33647309	2021
The Ca-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy. eLife\| PubMed ID: 34190686	2021
Mechanism-Based Cardiac Regeneration Strategies in Mammals. Frontiers in cell and developmental biology\| PubMed ID: 34708043	2021
Exploring the Genetic Architecture of Spontaneous Coronary Artery Dissection Using Whole-Genome Sequencing. Circulation. Genomic and precision medicine\| PubMed ID: 35583931	2022
Standardised method for cardiomyocyte isolation and purification from individual murine neonatal, infant, and adult hearts. Journal of molecular and cellular cardiology\| PubMed ID: 35644482	2022