a-modified-bilateral-scrotal-flap-for-penile-skin-defect-repair

A Modified Bilateral Scrotal Flap for Penile Skin Defect Repair

Skin shortages and scar contractures are common complications following penile trauma and tumor surgery, resulting in significant pain and erectile ...

Shanghai Jiao Tong University, School of Medicine

Extramammary Paget disease (EMPD) is a rare malignant dermatosis with poorly defined outcomes. We investigated clinical characteristics of invasive EMPD at different anatomic sites and by subject demographics to determine prognostic factors for overall survival (OS).

Survival analysis of patients with invasive extramammary Paget disease: implications of anatomic sites.

Tissue engineering is a promising alternative for urethral reconstruction, and adipose-derived stem cells (ADSCs) are widely used as seeding cells. Hypoxia preconditioning can significantly enhance the therapeutic effects of ADSCs. The low oxygen tension of postoperative wound healing is inevitable and may facilitate the nutritional function of ADSCs. This study aimed to investigate if hypoxia-preconditioned ADSCs, compared to normoxia-preconditioned ADSCs, combined with scaffold could better promote urethral reconstruction and exploring the underlying mechanism.

Hypoxia-preconditioned adipose-derived stem cells combined with scaffold promote urethral reconstruction by upregulation of angiogenesis and glycolysis.

Article	Year
Survival analysis of patients with invasive extramammary Paget disease: implications of anatomic sites. BMC cancer\| PubMed ID: 29636019	2018
Hypoxia-preconditioned adipose-derived stem cells combined with scaffold promote urethral reconstruction by upregulation of angiogenesis and glycolysis. Stem cell research & therapy\| PubMed ID: 33308306	2020

Dachao Zheng

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