Daniel Alcolea

Sant Pau Memory Unit, Universitat Autònoma de Barcelona

Affiliated withUniversitat Autònoma de Barcelona Center of Biomedical Investigation Network for Neurodegenerative Diseases (CIBERNED)

Research Area

Neuroscience

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 16	2022

Other Publications

Article	Year
Dementia risk in Parkinson disease: disentangling the role of MAPT haplotypes. Archives of neurology\| PubMed ID: 21403021	2011
Expansion mutation in C9ORF72 does not influence plasma progranulin levels in frontotemporal dementia. Neurobiology of aging\| PubMed ID: 22502998	2012
Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease. Acta neuropathologica\| PubMed ID: 23224319	2013
Characterization of the repeat expansion size in C9orf72 in amyotrophic lateral sclerosis and frontotemporal dementia. Human molecular genetics\| PubMed ID: 24057670	2014
Feasibility of lumbar puncture in the study of cerebrospinal fluid biomarkers for Alzheimer's disease: a multicenter study in Spain. Journal of Alzheimer's disease : JAD\| PubMed ID: 24254700	2014
Plasma phosphorylated TDP-43 levels are elevated in patients with frontotemporal dementia carrying a C9orf72 repeat expansion or a GRN mutation. Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 24309270	2014
Posttranslational nitro-glycative modifications of albumin in Alzheimer's disease: implications in cytotoxicity and amyloid-β peptide aggregation. Journal of Alzheimer's disease : JAD\| PubMed ID: 24503620	2014
Relationship between β-Secretase, inflammation and core cerebrospinal fluid biomarkers for Alzheimer's disease. Journal of Alzheimer's disease : JAD\| PubMed ID: 24820015	2014
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis. Science translational medicine\| PubMed ID: 24990881	2014
Early Cerebellar Hypometabolism in Patients With Frontotemporal Dementia Carrying the C9orf72 Expansion. Alzheimer disease and associated disorders\| PubMed ID: 25203513	2015
Cerebral amyloid angiopathy-related atraumatic convexal subarachnoid hemorrhage: an ARIA before the tsunami. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 25735919	2015
Relationship between cortical thickness and cerebrospinal fluid YKL-40 in predementia stages of Alzheimer's disease. Neurobiology of aging\| PubMed ID: 25865441	2015
Analysis of the CHCHD10 gene in patients with frontotemporal dementia and amyotrophic lateral sclerosis from Spain. Brain : a journal of neurology\| PubMed ID: 26152333	2015
Amyloid precursor protein metabolism and inflammation markers in preclinical Alzheimer disease. Neurology\| PubMed ID: 26180139	2015
Cerebrospinal Fluid Anti-Amyloid-β Autoantibodies and Amyloid PET in Cerebral Amyloid Angiopathy-Related Inflammation. Journal of Alzheimer's disease : JAD\| PubMed ID: 26639966	2016
Progranulin Protein Levels in Cerebrospinal Fluid in Primary Neurodegenerative Dementias. Journal of Alzheimer's disease : JAD\| PubMed ID: 26682689	2016
CSF microRNA Profiling in Alzheimer's Disease: a Screening and Validation Study. Molecular neurobiology\| PubMed ID: 27738874	2017
Feasibility of Lumbar Puncture in the Study of Cerebrospinal Fluid Biomarkers for Alzheimer's Disease in Subjects with Down Syndrome. Journal of Alzheimer's disease : JAD\| PubMed ID: 27858714	2017
A Common Variant in the MC1R Gene (p.V92M) is associated with Alzheimer's Disease Risk. Journal of Alzheimer's disease : JAD\| PubMed ID: 28059796	2017
Cerebrospinal fluid mitochondrial DNA in the Alzheimer's disease continuum. Neurobiology of aging\| PubMed ID: 28089353	2017
Cerebral amyloid angiopathy in Down syndrome and sporadic and autosomal-dominant Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 28463681	2017
Diagnostic and Prognostic Value of the Combination of Two Measures of Verbal Memory in Mild Cognitive Impairment due to Alzheimer's Disease. Journal of Alzheimer's disease : JAD\| PubMed ID: 28527215	2017
CSF sAPPβ, YKL-40, and neurofilament light in frontotemporal lobar degeneration. Neurology\| PubMed ID: 28592456	2017
The pitfalls of biomarker-based classification schemes. Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 28704640	2017
Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societie... The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry\| PubMed ID: 29076399	2018
Cortical microstructural changes along the Alzheimer's disease continuum. Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 29080407	2018
Weight loss in the healthy elderly might be a non-cognitive sign of preclinical Alzheimer's disease. Oncotarget\| PubMed ID: 29285207	2017
Cerebral changes and disrupted gray matter cortical networks in asymptomatic older adults at risk for Alzheimer's disease. Neurobiology of aging\| PubMed ID: 29331877	2018
Challenges associated with biomarker-based classification systems for Alzheimer's disease. Alzheimer's & dementia (Amsterdam, Netherlands)\| PubMed ID: 30175226	2018
Decreased CX3CL1 Levels in the Cerebrospinal Fluid of Patients With Alzheimer's Disease. Frontiers in neuroscience\| PubMed ID: 30245615	2018
CSF sAPPβ, YKL-40, and NfL along the ALS-FTD spectrum. Neurology\| PubMed ID: 30291183	2018
Elevated YKL-40 and low sAPPβ:YKL-40 ratio in antemortem cerebrospinal fluid of patients with pathologically confirmed FTLD. Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 30297518	2019
Impact of CSF storage volume on the analysis of Alzheimer's disease biomarkers on an automated platform. Clinica chimica acta; international journal of clinical chemistry\| PubMed ID: 30579960	2019
Cortical microstructure in the behavioural variant of frontotemporal dementia: looking beyond atrophy. Brain : a journal of neurology\| PubMed ID: 30906945	2019
A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta neuropathologica\| PubMed ID: 31131421	2019
The gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk. Science translational medicine\| PubMed ID: 31413141	2019
Agreement of amyloid PET and CSF biomarkers for Alzheimer's disease on Lumipulse. Annals of clinical and translational neurology\| PubMed ID: 31464088	2019
The Sant Pau Initiative on Neurodegeneration (SPIN) cohort: A data set for biomarker discovery and validation in neurodegenerative disorders. Alzheimer's & dementia (New York, N. Y.)\| PubMed ID: 31650016	2019
Detection of amyloid beta peptides in body fluids for the diagnosis of alzheimer's disease: Where do we stand? Critical reviews in clinical laboratory sciences\| PubMed ID: 31661652	2020
APP-derived peptides reflect neurodegeneration in frontotemporal dementia. Annals of clinical and translational neurology\| PubMed ID: 31789459	2019
Atrophy of Basal Forebrain Initiates with Tau Pathology in Individuals at Risk for Alzheimer's Disease. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 31799623	2020
Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta neuropathologica\| PubMed ID: 31955222	2020
Assessing circular RNAs in Alzheimer's disease and frontotemporal lobar degeneration. Neurobiology of aging\| PubMed ID: 32335360	2020
Disease-Specific Changes in Reelin Protein and mRNA in Neurodegenerative Diseases. Cells\| PubMed ID: 32438605	2020
Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome: a cross-sectional study. Lancet (London, England)\| PubMed ID: 32593336	2020
Motor cortex transcriptome reveals microglial key events in amyotrophic lateral sclerosis. Neurology(R) neuroimmunology & neuroinflammation\| PubMed ID: 32669313	2020
Obesity impacts brain metabolism and structure independently of amyloid and tau pathology in healthy elderly. Alzheimer's & dementia (Amsterdam, Netherlands)\| PubMed ID: 32743041	2020
Cortical microstructure in the amyotrophic lateral sclerosis-frontotemporal dementia continuum. Neurology\| PubMed ID: 32913016	2020
Cerebrospinal fluid A beta 1-40 peptides increase in Alzheimer's disease and are highly correlated with phospho-tau in control individuals. Alzheimer's research & therapy\| PubMed ID: 33008460	2020
Heterozygous APOE Christchurch in familial Alzheimer's disease without mutations in other Mendelian genes. Neuropathology and applied neurobiology\| PubMed ID: 33095930	2021
Serum neurofilament light chain predicts long-term prognosis in Guillain-Barré syndrome patients. Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 33154183	2020
Biphasic cortical macro- and microstructural changes in autosomal dominant Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 33196147	2021
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture. Nature genetics\| PubMed ID: 33589841	2021
Sex differences in the behavioral variant of frontotemporal dementia: A new window to executive and behavioral reserve. Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 33590953	2021
Diagnostic Utility of Measuring Cerebral Atrophy in the Behavioral Variant of Frontotemporal Dementia and Association With Clinical Deterioration. JAMA network open\| PubMed ID: 33704477	2021
AMYQ: An index to standardize quantitative amyloid load across PET tracers. Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 33797846	2021
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nature communications\| PubMed ID: 34099642	2021
Use of plasma biomarkers for AT(N) classification of neurodegenerative dementias. Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 34103344	2021
Association of Apolipoprotein E ɛ4 Allele With Clinical and Multimodal Biomarker Changes of Alzheimer Disease in Adults With Down Syndrome. JAMA neurology\| PubMed ID: 34228042	2021
Phosphorylated tau181 in plasma as a potential biomarker for Alzheimer's disease in adults with Down syndrome. Nature communications\| PubMed ID: 34262030	2021
Diagnostic and prognostic performance and longitudinal changes in plasma neurofilament light chain concentrations in adults with Down syndrome: a cohort study. The Lancet. Neurology\| PubMed ID: 34302785	2021
Metabolite Signature of Alzheimer's Disease in Adults with Down Syndrome. Annals of neurology\| PubMed ID: 34309066	2021
Cerebrospinal fluid levels of the neurotrophic factor neuroleukin are increased in early Alzheimer's disease, but not in cerebral amyloid angiopathy. Alzheimer's research & therapy\| PubMed ID: 34560885	2021
Correction to: Cerebrospinal fluid levels of the neurotrophic factor neuroleukin are increased in early Alzheimer's disease, but not in cerebral amyloid angiopathy. Alzheimer's research & therapy\| PubMed ID: 34784952	2021
Plasma glial fibrillary acidic protein and neurofilament light chain for the diagnostic and prognostic evaluation of frontotemporal dementia. Translational neurodegeneration\| PubMed ID: 34893073	2021
The Aβ1-42/Aβ1-40 ratio in CSF is more strongly associated to tau markers and clinical progression than Aβ1-42 alone. Alzheimer's research & therapy\| PubMed ID: 35105351	2022
Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders. Cell metabolism\| PubMed ID: 35108514	2022
Pathophysiological Underpinnings of Extra-Motor Neurodegeneration in Amyotrophic Lateral Sclerosis: New Insights From Biomarker Studies. Frontiers in neurology\| PubMed ID: 35115992	2021
Blood amyloid and tau biomarkers as predictors of cerebrospinal fluid profiles. Journal of neural transmission (Vienna, Austria : 1996)\| PubMed ID: 35169889	2022
New insights into the genetic etiology of Alzheimer's disease and related dementias. Nature genetics\| PubMed ID: 35379992	2022
Multimarker synaptic protein cerebrospinal fluid panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration. Molecular neurodegeneration\| PubMed ID: 35395770	2022
Importance of cerebrospinal fluid storage conditions for the Alzheimer's disease diagnostics on an automated platform. Clinical chemistry and laboratory medicine\| PubMed ID: 35405043	2022
Association of Alzheimer Disease With Life Expectancy in People With Down Syndrome. JAMA network open\| PubMed ID: 35604690	2022
Establishing In-House Cutoffs of CSF Alzheimer's Disease Biomarkers for the AT(N) Stratification of the Alzheimer Center Barcelona Cohort. International journal of molecular sciences\| PubMed ID: 35805894	2022
Intermediate and Expanded HTT Alleles and the Risk for α-Synucleinopathies. Movement disorders : official journal of the Movement Disorder Society\| PubMed ID: 35852957	2022