Christina Voelkel-Johnson

Department of Microbiology & Immunology, Medical University of South Carolina

Affiliated withMedical University of South Carolina

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 17	2012
Publication title Cited by 9	2013

Other Publications

Article	Year
Resistance of prostate cancer cells to soluble TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) can be overcome by doxorubicin or adenoviral delivery of full-length TRAIL. Cancer gene therapy\| PubMed ID: 11857034	2002
Doxorubicin pretreatment sensitizes prostate cancer cell lines to TRAIL induced apoptosis which correlates with the loss of c-FLIP expression. Cancer biology & therapy\| PubMed ID: 12496481	2002
An antibody against DR4 (TRAIL-R1) in combination with doxorubicin selectively kills malignant but not normal prostate cells. Cancer biology & therapy\| PubMed ID: 12878867	2003
Enhanced apoptosis of glioma cell lines is achieved by co-delivering FasL-GFP and TRAIL with a complex Ad5 vector. Cancer gene therapy\| PubMed ID: 14605667	2003
In vitro efficacy of Fas ligand gene therapy for the treatment of bladder cancer. Cancer gene therapy\| PubMed ID: 15514684	2005
Doxorubicin increases the effectiveness of Apo2L/TRAIL for tumor growth inhibition of prostate cancer xenografts. BMC cancer\| PubMed ID: 15638938	2005
Resistance to TRAIL is associated with defects in ceramide signaling that can be overcome by exogenous C6-ceramide without requiring down-regulation of cellular FLICE inhibitory protein. Molecular cancer therapeutics\| PubMed ID: 16170023	2005
Targeting the short form of cFLIP by RNA interference is sufficient to enhance TRAIL sensitivity in PC3 prostate carcinoma cells. Cancer biology & therapy\| PubMed ID: 17106251	2006
Illuminating TRAIL gene therapy. Cancer biology & therapy\| PubMed ID: 17204862	2006
Doxorubicin generates a proapoptotic phenotype by phosphorylation of elongation factor 2. Free radical biology & medicine\| PubMed ID: 17893044	2007
Transformation, translation and TRAIL: an unexpected intersection. Cytokine & growth factor reviews\| PubMed ID: 18353705	2008
径组合疗法：最近的事态发展和潜在的陷阱。 Cancer biology & therapy\| PubMed ID: 19127121	2009
MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism. Molecular cancer therapeutics\| PubMed ID: 19417161	2009
Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms. Molecular pharmacology\| PubMed ID: 19483104	2009
The role of protein synthesis in cell cycling and cancer. Molecular oncology\| PubMed ID: 19546037	2009
Oxidative stress and lymphocyte persistence: implications in immunotherapy. Advances in cancer research\| PubMed ID: 19595310	2009
Oxidative stress sensitizes bladder cancer cells to TRAIL mediated apoptosis by down-regulating anti-apoptotic proteins. The Journal of urology\| PubMed ID: 19625063	2009
Inhibition of superoxide generation upon T-cell receptor engagement rescues Mart-1(27-35)-reactive T cells from activation-induced cell death. Cancer research\| PubMed ID: 19638595	2009
Polymer-enhanced adenoviral transduction of CAR-negative bladder cancer cells. Molecular pharmaceutics\| PubMed ID: 19655763	2009
17-allylamino-17-demethoxygeldanamycin and MEK1/2 inhibitors kill GI tumor cells via Ca2+-dependent suppression of GRP78/BiP and induction of ceramide and reactive oxygen species. Molecular cancer therapeutics\| PubMed ID: 20442308	2010
Vorinostat and sorafenib increase CD95 activation in gastrointestinal tumor cells through a Ca(2+)-de novo ceramide-PP2A-reactive oxygen species-dependent signaling pathway. Cancer research\| PubMed ID: 20631069	2010
Sorafenib activates CD95 and promotes autophagy and cell death via Src family kinases in gastrointestinal tumor cells. Molecular cancer therapeutics\| PubMed ID: 20682655	2010
Adenoviral infectivity of exfoliated viable cells in urine: implications for the detection of bladder cancer. BMC cancer\| PubMed ID: 21569442	2011
T cells expanded in presence of IL-15 exhibit increased antioxidant capacity and innate effector molecules. Cytokine\| PubMed ID: 21602054	2011
TRAIL-mediated signaling in prostate, bladder and renal cancer. Nature reviews. Urology\| PubMed ID: 21670755	2011
Histone deacetylase inhibitors restore cell surface expression of the coxsackie adenovirus receptor and enhance CMV promoter activity in castration-resistant prostate cancer cells. Prostate cancer\| PubMed ID: 22288017	2012
Inner ear supporting cells protect hair cells by secreting HSP70. The Journal of clinical investigation\| PubMed ID: 23863716	2013
Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma. Molecular cancer therapeutics\| PubMed ID: 24140934	2013