Evelien Smits

Center for Oncological Research (CORE), University of Antwerp

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 14	2022

Other Publications

Article	Year
Can cervical cancer screening be stopped at 50? The prevalence of HPV in elderly women. International journal of cancer\| PubMed ID: 14639612	2004
The use of TLR7 and TLR8 ligands for the enhancement of cancer immunotherapy. The oncologist\| PubMed ID: 18701762	2008
Immunotherapy of acute myeloid leukemia: current approaches. The oncologist\| PubMed ID: 19289488	2009
The Toll-like receptor 7/8 agonist resiquimod greatly increases the immunostimulatory capacity of human acute myeloid leukemia cells. Cancer immunology, immunotherapy : CII\| PubMed ID: 19449004	2010
Dendritic cell-based cancer gene therapy. Human gene therapy\| PubMed ID: 19656053	2009
Short-term cultured, interleukin-15 differentiated dendritic cells have potent immunostimulatory properties. Journal of translational medicine\| PubMed ID: 20021667	2009
The effect of apoptotic cells on virus-specific immune responses detected using IFN-gamma ELISPOT. Journal of immunological methods\| PubMed ID: 20214906	2010
Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20631300	2010
Dendritic cell vaccine therapy for acute myeloid leukemia: questions and answers. Human vaccines\| PubMed ID: 21422813	2011
Exploring the impact of exposure to primary varicella in children on varicella-zoster virus immunity of parents. Viral immunology\| PubMed ID: 21449725	2011
Clinical evaluation of cellular immunotherapy in acute myeloid leukaemia. Cancer immunology, immunotherapy : CII\| PubMed ID: 21519825	2011
Poly(I:C) enhances the susceptibility of leukemic cells to NK cell cytotoxicity and phagocytosis by DC. PloS one\| PubMed ID: 21698118	2011
Dendritic cells in the pathogenesis and treatment of human diseases: a Janus Bifrons? Immunotherapy\| PubMed ID: 21995572	2011
Dendritic cell vaccination in acute myeloid leukemia. Cytotherapy\| PubMed ID: 22686130	2012
Sampling site matters when counting lymphocyte subpopulations. PloS one\| PubMed ID: 22848485	2012
NK cells: key to success of DC-based cancer vaccines? The oncologist\| PubMed ID: 22907975	2012
Interleukin-15-induced CD56(+) myeloid dendritic cells combine potent tumor antigen presentation with direct tumoricidal potential. PloS one\| PubMed ID: 23284789	2012
CD56 marks human dendritic cell subsets with cytotoxic potential. Oncoimmunology\| PubMed ID: 23524451	2013
Interferon α may be back on track to treat acute myeloid leukemia. Oncoimmunology\| PubMed ID: 23734314	2013
Interleukin-15 dendritic cells as vaccine candidates for cancer immunotherapy. Human vaccines & immunotherapeutics\| PubMed ID: 23778748	2013
Tumoricidal activity of human dendritic cells. Trends in immunology\| PubMed ID: 24262387	2013
Influence of frequent infectious exposures on general and varicella-zoster virus-specific immune responses in pediatricians. Clinical and vaccine immunology : CVI\| PubMed ID: 24429070	2014
Loading of acute myeloid leukemia cells with poly(I:C) by electroporation. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 24619684	2014
Clinical use of dendritic cells for cancer therapy. The Lancet. Oncology\| PubMed ID: 24872109	2014
HPV vaccine stimulates cytotoxic activity of killer dendritic cells and natural killer cells against HPV-positive tumour cells. Journal of cellular and molecular medicine\| PubMed ID: 24979331	2014
Induction of cytomegalovirus-specific T cell responses in healthy volunteers and allogeneic stem cell recipients using vaccination with messenger RNA-transfected dendritic cells. Transplantation\| PubMed ID: 25050468	2015
Poly(I:C) as cancer vaccine adjuvant: knocking on the door of medical breakthroughs. Pharmacology & therapeutics\| PubMed ID: 25281915	2015
Interleukin-15: new kid on the block for antitumor combination therapy. Cytokine & growth factor reviews\| PubMed ID: 25306466	2015
Engineering monocyte-derived dendritic cells to secrete interferon-α enhances their ability to promote adaptive and innate anti-tumor immune effector functions. Cancer immunology, immunotherapy : CII\| PubMed ID: 25863943	2015
Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner. PloS one\| PubMed ID: 25951230	2015
Dendritic Cells as Pharmacological Tools for Cancer Immunotherapy. Pharmacological reviews\| PubMed ID: 26240218	2015
Targeting immune checkpoints: New opportunity for mesothelioma treatment? Cancer treatment reviews\| PubMed ID: 26433514	2015
Generation of a cord blood-derived Wilms Tumor 1 dendritic cell vaccine for AML patients treated with allogeneic cord blood transplantation. Oncoimmunology\| PubMed ID: 26451309	2015
Application of the pMHC Array to Characterise Tumour Antigen Specific T Cell Populations in Leukaemia Patients at Disease Diagnosis. PloS one\| PubMed ID: 26492414	2015
Immune Checkpoint Modulation in Colorectal Cancer: What's New and What to Expect. Journal of immunology research\| PubMed ID: 26605342	2015
Bisphosphonates for cancer treatment: Mechanisms of action and lessons from clinical trials. Pharmacology & therapeutics\| PubMed ID: 26617219	2016
Transpresentation of interleukin-15 by IL-15/IL-15Rα mRNA-engineered human dendritic cells boosts antitumoral natural killer cell activity. Oncotarget\| PubMed ID: 26675759	2015
Generation and Cryopreservation of Clinical Grade Wilms' Tumor 1 mRNA-Loaded Dendritic Cell Vaccines for Cancer Immunotherapy. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 27033213	2016
Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines. Cancer research\| PubMed ID: 27325645	2016
Dendritic Cells as Vaccines: Key Regulators of Tolerance and Immunity. Mediators of inflammation\| PubMed ID: 27340343	2016
The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells. Oncotarget\| PubMed ID: 27659531	2016
Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells. Journal of hematology & oncology\| PubMed ID: 27686372	2016
IL-15 receptor alpha as the magic wand to boost the success of IL-15 antitumor therapies: The upswing of IL-15 transpresentation. Pharmacology & therapeutics\| PubMed ID: 27777088	2017
Human blood myeloid and plasmacytoid dendritic cells cross activate each other and synergize in inducing NK cell cytotoxicity. Oncoimmunology\| PubMed ID: 27853652	2016
Desirable cytolytic immune effector cell recruitment by interleukin-15 dendritic cells. Oncotarget\| PubMed ID: 28099143	2017
Prognostic and predictive aspects of the tumor immune microenvironment and immune checkpoints in malignant pleural mesothelioma. Oncoimmunology\| PubMed ID: 28197385	2017
CD70 and PD-L1 in anaplastic thyroid cancer - promising targets for immunotherapy. Histopathology\| PubMed ID: 28383817	2017
Multidisciplinary study of the secondary immune response in grandparents re-exposed to chickenpox. Scientific reports\| PubMed ID: 28439065	2017
Monocyte-Derived Dendritic Cells with Silenced PD-1 Ligands and Transpresenting Interleukin-15 Stimulate Strong Tumor-Reactive T-cell Expansion. Cancer immunology research\| PubMed ID: 28637876	2017
Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections. The Journal of clinical investigation\| PubMed ID: 28783042	2017
CD56 in the Immune System: More Than a Marker for Cytotoxicity? Frontiers in immunology\| PubMed ID: 28791027	2017
Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia. Blood\| PubMed ID: 28830889	2017
Interleukin-15 stimulates natural killer cell-mediated killing of both human pancreatic cancer and stellate cells. Oncotarget\| PubMed ID: 28915646	2017
Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy. Oncotarget\| PubMed ID: 29088768	2017
Abundant expression of TIM-3, LAG-3, PD-1 and PD-L1 as immunotherapy checkpoint targets in effusions of mesothelioma patients. Oncotarget\| PubMed ID: 29163783	2017
Anti-cancer capacity of plasma-treated PBS: effect of chemical composition on cancer cell cytotoxicity. Scientific reports\| PubMed ID: 29184131	2017
Increased herpes zoster risk associated with poor HLA-A immediate early 62 protein (IE62) affinity. Immunogenetics\| PubMed ID: 29196796	2018
Poly(I:C) primes primary human glioblastoma cells for an immune response invigorated by PD-L1 blockade. Oncoimmunology\| PubMed ID: 29399410	2018
Identification of survivin as a promising target for the immunotherapy of adult B-cell acute lymphoblastic leukemia. Oncotarget\| PubMed ID: 29423088	2018
Dendritic Cells and Programmed Death-1 Blockade: A Joint Venture to Combat Cancer. Frontiers in immunology\| PubMed ID: 29599770	2018
Combining top-ranked immunotherapeutics in lung cancer. The Lancet. Oncology\| PubMed ID: 29628313	2018
Natural killer cells and their therapeutic role in pancreatic cancer: A systematic review. Pharmacology & therapeutics\| PubMed ID: 29660367	2018
Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress. Cancers\| PubMed ID: 29690507	2018
Interleukin-15-Cultured Dendritic Cells Enhance Anti-Tumor Gamma Delta T Cell Functions through IL-15 Secretion. Frontiers in immunology\| PubMed ID: 29692776	2018
The role of the common gamma-chain family cytokines in γδ T cell-based anti-cancer immunotherapy. Cytokine & growth factor reviews\| PubMed ID: 29773448	2018
Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation. Oncoimmunology\| PubMed ID: 29900042	2018
Memory CD4 T cell receptor repertoire data mining as a tool for identifying cytomegalovirus serostatus. Genes and immunity\| PubMed ID: 29904098	2019
Vaccine and immune cell therapy in non-small cell lung cancer. Journal of thoracic disease\| PubMed ID: 29951309	2018
Author Correction: Multidisciplinary study of the secondary immune response in grandparents re-exposed to chickenpox. Scientific reports\| PubMed ID: 30002465	2018
Transcriptome profiling in blood before and after hepatitis B vaccination shows significant differences in gene expression between responders and non-responders. Vaccine\| PubMed ID: 30205979	2018
BDCA1+CD14+ Immunosuppressive Cells in Cancer, a Potential Target? Vaccines\| PubMed ID: 30235890	2018
Reduction of Human Glioblastoma Spheroids Using Cold Atmospheric Plasma: The Combined Effect of Short- and Long-Lived Reactive Species. Cancers\| PubMed ID: 30360539	2018
Efficient and Non-genotoxic RNA-Based Engineering of Human T Cells Using Tumor-Specific T Cell Receptors With Minimal TCR Mispairing. Frontiers in immunology\| PubMed ID: 30464762	2018
RANK/RANKL signaling inhibition may improve the effectiveness of checkpoint blockade in cancer treatment. Critical reviews in oncology/hematology\| PubMed ID: 30661662	2019
Non-Thermal Plasma as a Unique Delivery System of Short-Lived Reactive Oxygen and Nitrogen Species for Immunogenic Cell Death in Melanoma Cells. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 30937272	2019
RANK-RANKL Signaling in Cancer of the Uterine Cervix: A Review. International journal of molecular sciences\| PubMed ID: 31052546	2019
CD56 Homodimerization and Participation in Anti-Tumor Immune Effector Cell Functioning: A Role for Interleukin-15. Cancers\| PubMed ID: 31336622	2019
Building a Bridge between Chemotherapy and Immunotherapy in Malignant Pleural Mesothelioma: Investigating the Effect of Chemotherapy on Immune Checkpoint Expression. International journal of molecular sciences\| PubMed ID: 31455014	2019
Influence of Cell Type and Culture Medium on Determining Cancer Selectivity of Cold Atmospheric Plasma Treatment. Cancers\| PubMed ID: 31480642	2019
Desmoid tumors display a strong immune infiltration at the tumor margins and no PD-L1-driven immune suppression. Cancer immunology, immunotherapy : CII\| PubMed ID: 31511925	2019
Dendritic Cell-Based and Other Vaccination Strategies for Pediatric Cancer. Cancers\| PubMed ID: 31546858	2019
The potential and controversy of targeting STAT family members in cancer. Seminars in cancer biology\| PubMed ID: 31605750	2020
Cold Atmospheric Plasma-Treated PBS Eliminates Immunosuppressive Pancreatic Stellate Cells and Induces Immunogenic Cell Death of Pancreatic Cancer Cells. Cancers\| PubMed ID: 31635070	2019
Screening a Broad Range of Solid and Haematological Tumour Types for CD70 Expression Using a Uniform IHC Methodology as Potential Patient Stratification Method. Cancers\| PubMed ID: 31652572	2019
Modifying the Tumour Microenvironment: Challenges and Future Perspectives for Anticancer Plasma Treatments. Cancers\| PubMed ID: 31810265	2019
New targets for therapy: antigen identification in adults with B-cell acute lymphoblastic leukaemia. Cancer immunology, immunotherapy : CII\| PubMed ID: 31970440	2020
Ribonucleic Acid Engineering of Dendritic Cells for Therapeutic Vaccination: Ready 'N Able to Improve Clinical Outcome? Cancers\| PubMed ID: 32012714	2020
Mass Spectrometry Imaging Reveals Neutrophil Defensins as Additional Biomarkers for Anti-PD-(L)1 Immunotherapy Response in NSCLC Patients. Cancers\| PubMed ID: 32252405	2020
Cetuximab-induced natural killer cell cytotoxicity in head and neck squamous cell carcinoma cell lines: investigation of the role of cetuximab sensitivity and HPV status. British journal of cancer\| PubMed ID: 32541873	2020
SARS-CoV-2 and cancer: Are they really partners in crime? Cancer treatment reviews\| PubMed ID: 32731090	2020
Novel combination immunotherapy for pancreatic cancer: potent anti-tumor effects with CD40 agonist and interleukin-15 treatment. Clinical & translational immunology\| PubMed ID: 32821382	2020
Cold Atmospheric Plasma Treatment for Pancreatic Cancer-The Importance of Pancreatic Stellate Cells. Cancers\| PubMed ID: 32998311	2020
Oxidative Stress-Inducing Anticancer Therapies: Taking a Closer Look at Their Immunomodulating Effects. Antioxidants (Basel, Switzerland)\| PubMed ID: 33260826	2020
Patient-derived organoids as individual patient models for chemoradiation response prediction in gastrointestinal malignancies. Critical reviews in oncology/hematology\| PubMed ID: 33310278	2021
Critical Evaluation of the Interaction of Reactive Oxygen and Nitrogen Species with Blood to Inform the Clinical Translation of Nonthermal Plasma Therapy. Oxidative medicine and cellular longevity\| PubMed ID: 33343810	2020
The Search for an Interesting Partner to Combine with PD-L1 Blockade in Mesothelioma: Focus on TIM-3 and LAG-3. Cancers\| PubMed ID: 33466653	2021
Immune Checkpoint Inhibitory Therapy in Sarcomas: Is There Light at the End of the Tunnel? Cancers\| PubMed ID: 33478080	2021
Oxidation of Innate Immune Checkpoint CD47 on Cancer Cells with Non-Thermal Plasma. Cancers\| PubMed ID: 33540720	2021
Physical plasma-derived oxidants sensitize pancreatic cancer cells to ferroptotic cell death. Free radical biology & medicine\| PubMed ID: 33636332	2021
Targeting the PD-1 Axis with Pembrolizumab for Recurrent or Metastatic Cancer of the Uterine Cervix: A Brief Update. International journal of molecular sciences\| PubMed ID: 33670397	2021
Cancer-Associated Fibroblasts as a Common Orchestrator of Therapy Resistance in Lung and Pancreatic Cancer. Cancers\| PubMed ID: 33673405	2021
Immunoglobin G/total antibody testing for SARS-CoV-2: A prospective cohort study of ambulatory patients and health care workers in two Belgian oncology units comparing three commercial tests... European journal of cancer (Oxford, England : 1990)\| PubMed ID: 33773276	2021
Fusions in Sarcomas: Diagnostic Challenges and Clinical Aspects. Diagnostics (Basel, Switzerland)\| PubMed ID: 33803146	2021
Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer. Redox biology\| PubMed ID: 33812801	2021
Oxidative damage to hyaluronan-CD44 interactions as an underlying mechanism of action of oxidative stress-inducing cancer therapy. Redox biology\| PubMed ID: 33895486	2021
Cold Atmospheric Plasma Increases Temozolomide Sensitivity of Three-Dimensional Glioblastoma Spheroids via Oxidative Stress-Mediated DNA Damage. Cancers\| PubMed ID: 33917880	2021
Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation. Science advances\| PubMed ID: 33962944	2021
A systematic review on poly(I:C) and poly-ICLC in glioblastoma: adjuvants coordinating the unlocking of immunotherapy. Journal of experimental & clinical cancer research : CR\| PubMed ID: 34172082	2021
Auranofin and Cold Atmospheric Plasma Synergize to Trigger Distinct Cell Death Mechanisms and Immunogenic Responses in Glioblastoma. Cells\| PubMed ID: 34831159	2021
Targeting hedgehog signaling in pancreatic ductal adenocarcinoma. Pharmacology & therapeutics\| PubMed ID: 34999181	2022
Preexisting memory CD4 T cells in naïve individuals confer robust immunity upon hepatitis B vaccination. eLife\| PubMed ID: 35074048	2022
Cold Atmospheric Plasma Does Not Affect Stellate Cells Phenotype in Pancreatic Cancer Tissue in Ovo. International journal of molecular sciences\| PubMed ID: 35216069	2022
Anti-Tumor Potency of Short-Term Interleukin-15 Dendritic Cells Is Potentiated by Silencing of Programmed-Death Ligands. Frontiers in immunology\| PubMed ID: 35250967	2022
Recent Advances of Immune Checkpoint Inhibition and Potential for (Combined) TIGIT Blockade as a New Strategy for Malignant Pleural Mesothelioma. Biomedicines\| PubMed ID: 35327475	2022
Modulating the Antioxidant Response for Better Oxidative Stress-Inducing Therapies: How to Take Advantage of Two Sides of the Same Medal? Biomedicines\| PubMed ID: 35453573	2022
Radionuclide Imaging of Cytotoxic Immune Cell Responses to Anti-Cancer Immunotherapy. Biomedicines\| PubMed ID: 35625811	2022
Fusions in a Sarcomas Series: Pathology, Molecular and Clinical Aspects. Pathology oncology research : POR\| PubMed ID: 35645621	2022
Trial watch: Dendritic cell (DC)-based immunotherapy for cancer. Oncoimmunology\| PubMed ID: 35800158	2022
New Implications of Patients' Sex in Today's Lung Cancer Management. Cancers\| PubMed ID: 35884463	2022
Expression of SARS-CoV-2-Related Surface Proteins in Non-Small-Cell Lung Cancer Patients and the Influence of Standard of Care Therapy. Cancers\| PubMed ID: 36077610	2022
The effect of local non-thermal plasma therapy on the cancer-immunity cycle in a melanoma mouse model. Bioengineering & translational medicine\| PubMed ID: 36176603	2022
The pro- and anti-tumoral properties of gap junctions in cancer and their role in therapeutic strategies. Redox biology\| PubMed ID: 36228438	2022
The prognostic impact of the immune signature in head and neck squamous cell carcinoma. Frontiers in immunology\| PubMed ID: 36268020	2022
Humoral and cellular immune responses against SARS-CoV-2 after third dose BNT162b2 following double-dose vaccination with BNT162b2 versus ChAdOx1 in cancer patients. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 36341493	2022
Challenges in neoantigen-directed therapeutics. Cancer cell\| PubMed ID: 36368320	2022
OrBITS: label-free and time-lapse monitoring of patient derived organoids for advanced drug screening. Cellular oncology (Dordrecht)\| PubMed ID: 36508089	2022