John A. Wemmie

Department of Psychiatry, University of Iowa

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2022

Other Publications

Article	Year
Interaction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel). The Biochemical journal\| PubMed ID: 11802773	2002
Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11854527	2002
The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory. Neuron\| PubMed ID: 11988176	2002
cAMP-dependent protein kinase phosphorylation of the acid-sensing ion channel-1 regulates its binding to the protein interacting with C-kinase-1. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12578970	2003
Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12843249	2003
Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1. Pain\| PubMed ID: 14659506	2003
Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neurons. The Journal of biological chemistry\| PubMed ID: 14960591	2004
Stimulation of Posterior Thalamic Nuclei Induces Photophobic Behavior in Mice. Headache\| PubMed ID: 32750230	2020
Overexpression of acid-sensing ion channel 1a in transgenic mice increases acquired fear-related behavior. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14988500	2004
Impaired motor performance and learning in glia maturation factor-knockout mice. Brain research\| PubMed ID: 15451385	2004
Stomatin modulates gating of acid-sensing ion channels. The Journal of biological chemistry\| PubMed ID: 15471860	2004
Functional correction of CNS phenotypes in a lysosomal storage disease model using adeno-associated virus type 4 vectors. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16221840	2005
Acid-sensing ion channels: advances, questions and therapeutic opportunities. Trends in neurosciences\| PubMed ID: 16891000	2006
Acid-sensing ion channel 1a is a postsynaptic proton receptor that affects the density of dendritic spines. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17060608	2006
Targeting ASIC1a reduces innate fear and alters neuronal activity in the fear circuit. Biological psychiatry\| PubMed ID: 17662962	2007
Seizure termination by acidosis depends on ASIC1a. Nature neuroscience\| PubMed ID: 18536711	2008
The cytoskeletal protein alpha-actinin regulates acid-sensing ion channel 1a through a C-terminal interaction. The Journal of biological chemistry\| PubMed ID: 19028690	2009
Restoring Acid-sensing ion channel-1a in the amygdala of knock-out mice rescues fear memory but not unconditioned fear responses. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19091964	2008
Oxidant regulated inter-subunit disulfide bond formation between ASIC1a subunits. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19218436	2009
Acid-sensing ion channel-1a in the amygdala, a novel therapeutic target in depression-related behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19403806	2009
Stereotactic atlas-based depth electrode localization in the human amygdala. Stereotactic and functional neurosurgery\| PubMed ID: 19556831	2009
Role of calcitonin gene-related peptide in light-aversive behavior: implications for migraine. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19587287	2009
Acid-sensing ion channels: A new target for pain and CNS diseases. Current opinion in drug discovery & development\| PubMed ID: 19736627	2009
The amygdala is a chemosensor that detects carbon dioxide and acidosis to elicit fear behavior. Cell\| PubMed ID: 19945383	2009
ASIC1 and ASIC3 play different roles in the development of Hyperalgesia after inflammatory muscle injury. The journal of pain\| PubMed ID: 20015700	2010
Amygdala volume correlates positively with fearfulness in normal healthy girls. Social cognitive and affective neuroscience\| PubMed ID: 20150341	2010
Neonatal leptin administration alters regional brain volumes and blocks neonatal growth restriction-induced behavioral and cardiovascular dysfunction in male mice. Pediatric research\| PubMed ID: 21258265	2011
Histologic examination of the eye of acid-sensing ion channel 1a knockout mice. International journal of physiology, pathophysiology and pharmacology\| PubMed ID: 21383900	2010
Maternal antioxidant blocks programmed cardiovascular and behavioural stress responses in adult mice. Clinical science (London, England : 1979)\| PubMed ID: 21615331	2011
Neurobiology of panic and pH chemosensation in the brain. Dialogues in clinical neuroscience\| PubMed ID: 22275852	2011
Detecting activity-evoked pH changes in human brain. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22566645	2012
Fear and panic in humans with bilateral amygdala damage. Nature neuroscience\| PubMed ID: 23377128	2013
Acid-sensing ion channels in pain and disease. Nature reviews. Neuroscience\| PubMed ID: 23783197	2013
Functional t1ρ imaging in panic disorder. Biological psychiatry\| PubMed ID: 24157339	2014
Localization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli. Genes, brain, and behavior\| PubMed ID: 24256442	2014
PRICKLE1 interaction with SYNAPSIN I reveals a role in autism spectrum disorders. PloS one\| PubMed ID: 24312498	2013
Acid-sensing ion channels 1a (ASIC1a) inhibit neuromuscular transmission in female mice. American journal of physiology. Cell physiology\| PubMed ID: 24336653	2014
Regulator of G-protein signaling 6 (RGS6) promotes anxiety and depression by attenuating serotonin-mediated activation of the 5-HT(1A) receptor-adenylyl cyclase axis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 24421401	2014
Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity. Nature neuroscience\| PubMed ID: 24952644	2014
Drug abuse and the simplest neurotransmitter. ACS chemical neuroscience\| PubMed ID: 25054738	2014
The bed nucleus of the stria terminalis is critical for anxiety-related behavior evoked by CO2 and acidosis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 25080586	2014
Rapid acquisition strategy for functional T1ρ mapping of the brain. Magnetic resonance imaging\| PubMed ID: 25093630	2014
Brain abnormalities in bipolar disorder detected by quantitative T1ρ mapping. Molecular psychiatry\| PubMed ID: 25560762	2015
Eccentricity mapping of the human visual cortex to evaluate temporal dynamics of functional T1ρ mapping. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 25966957	2015
Breathing Inhibited When Seizures Spread to the Amygdala and upon Amygdala Stimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 26180203	2015
ASIC1A in the bed nucleus of the stria terminalis mediates TMT-evoked freezing. Frontiers in neuroscience\| PubMed ID: 26257596	2015
Peripheral inflammation during abnormal mood states in bipolar I disorder. Journal of affective disorders\| PubMed ID: 26339927	2015
Extinction of Cocaine Seeking Requires a Window of Infralimbic Pyramidal Neuron Activity after Unreinforced Lever Presses. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 28539416	2017
Transient acidosis while retrieving a fear-related memory enhances its lability. eLife\| PubMed ID: 28650315	2017
Impaired sensory processing measured by functional MRI in Bipolar disorder manic and depressed mood states. Brain imaging and behavior\| PubMed ID: 28674759	2018
Relationship altered between functional T1ρ and BOLD signals in bipolar disorder. Brain and behavior\| PubMed ID: 29075562	2017
Alterations of the cerebellum and basal ganglia in bipolar disorder mood states detected by quantitative T1ρ mapping. Bipolar disorders\| PubMed ID: 29316081	2018
Attenuation of cocaine seeking in rats via enhancement of infralimbic cortical activity using stable step-function opsins. Psychopharmacology\| PubMed ID: 30003306	2019
A novel role for acid-sensing ion channels in Pavlovian reward conditioning. Genes, brain, and behavior\| PubMed ID: 30375184	2019
Overexpression of ASIC1A in the nucleus accumbens of rats potentiates cocaine-seeking behavior. Addiction biology\| PubMed ID: 30397978	2020
Acid-Sensing Ion Channels: Novel Mediators of Cerebral Vascular Responses. Circulation research\| PubMed ID: 31451088	2019
Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on calcium. Journal of neuroscience research\| PubMed ID: 31452242	2019
The amygdala differentially regulates defensive behaviors evoked by CO. Behavioural brain research\| PubMed ID: 31536735	2020
A human amygdala site that inhibits respiration and elicits apnea in pediatric epilepsy. JCI insight\| PubMed ID: 32163374	2020
Comparison of TRho MRI, Glucose Metabolism, and Amyloid Burden Across the Cognitive Spectrum: A Pilot Study. The Journal of neuropsychiatry and clinical neurosciences\| PubMed ID: 32283991	2020
Proton Exchange Magnetic Resonance Imaging: Current and Future Applications in Psychiatric Research. Frontiers in psychiatry\| PubMed ID: 33192650	2020
A mouse model of Bardet-Biedl Syndrome has impaired fear memory, which is rescued by lithium treatment. PLoS genetics\| PubMed ID: 33886537	2021
Post-acquisition CO Inhalation Enhances Fear Memory and Depends on ASIC1A. Frontiers in behavioral neuroscience\| PubMed ID: 34776896	2021
Posterior Fossa Sub-Arachnoid Cysts Observed in Patients with Bipolar Disorder: a Retrospective Cohort Study. Cerebellum (London, England)\| PubMed ID: 35568792	2022