Pavel Georgiev

Department of the Control of Genetic Processes, Russian Academy of Sciences

Affiliated withRussian Academy of Sciences Russian Academy of Sciences

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2022

Other Publications

Article	Year
P element-mediated duplications of genomic regions in Drosophila melanogaster. Chromosoma\| PubMed ID: 12111335	2002
The su(Hw) insulator can disrupt enhancer-promoter interactions when located more than 20 kilobases away from the Drosophila achaete-scute complex. Molecular and cellular biology\| PubMed ID: 10207068	1999
TAFII40 protein is encoded by the e(y)1 gene: biological consequences of mutations. Molecular and cellular biology\| PubMed ID: 10207100	1999
Attachment of HeT-A sequences to chromosomal termini in Drosophila melanogaster may occur by different mechanisms. Molecular and cellular biology\| PubMed ID: 11003659	2000
The novel transcription factor e(y)2 interacts with TAF(II)40 and potentiates transcription activation on chromatin templates. Molecular and cellular biology\| PubMed ID: 11438676	2001
Heterochromatin protein 1 is involved in control of telomere elongation in Drosophila melanogaster. Molecular and cellular biology\| PubMed ID: 11940677	2002
The gypsy insulators flanking yellow enhancers do not form a separate transcriptional domain in Drosophila melanogaster: the enhancers can activate an isolated yellow promoter. Genetics\| PubMed ID: 11973309	2002
Enhancer of terminal gene conversion, a new mutation in Drosophila melanogaster that induces telomere elongation by gene conversion. Genetics\| PubMed ID: 12454074	2002
Transvection at the end of the truncated chromosome in Drosophila melanogaster. Genetics\| PubMed ID: 12702682	2003
An endogenous Su(Hw) insulator separates the yellow gene from the Achaete-scute gene complex in Drosophila. Development (Cambridge, England)\| PubMed ID: 12783795	2003
The Mod(mdg4) component of the Su(Hw) insulator inserted in the P transposon can repress its mobility in Drosophila melanogaster. Genetics\| PubMed ID: 15280241	2004
Interaction between the GAGA factor and Mod(mdg4) proteins promotes insulator bypass in Drosophila. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15465920	2004
Drosophila Su(Hw) insulator can stimulate transcription of a weakened yellow promoter over a distance. Genetics\| PubMed ID: 15520254	2005
A novel multidomain transcription coactivator SAYP can also repress transcription in heterochromatin. The EMBO journal\| PubMed ID: 15616585	2005
The Ku protein complex is involved in length regulation of Drosophila telomeres. Genetics\| PubMed ID: 15781709	2005
The Mcp element from the bithorax complex contains an insulator that is capable of pairwise interactions and can facilitate enhancer-promoter communication. Molecular and cellular biology\| PubMed ID: 15831473	2005
Drosophila telomeres: the non-telomerase alternative. Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology\| PubMed ID: 16132809	2005
Pairing between gypsy insulators facilitates the enhancer action in trans throughout the Drosophila genome. Molecular and cellular biology\| PubMed ID: 16227580	2005
Handling three regulatory elements in one transgene: combined use of cre-lox, FLP-FRT, and I-Scel recombination systems. BioTechniques\| PubMed ID: 16382906	2005
Transposition of Regulatory Elements by P-Element-Mediated Rearrangements in Drosophila melanogaster. Genetics\| PubMed ID: 16387869	2006
Study of long-distance functional interactions between Su(Hw) insulators that can regulate enhancer-promoter communication in Drosophila melanogaster. Molecular and cellular biology\| PubMed ID: 16428433	2006
Telomere elongation is under the control of the RNAi-based mechanism in the Drosophila germline. Genes & development\| PubMed ID: 16452506	2006
Two isoforms of Drosophila TRF2 are involved in embryonic development, premeiotic chromatin condensation, and proper differentiation of germ cells of both sexes. Molecular and cellular biology\| PubMed ID: 17015475	2006
Integrity of the Mod(mdg4)-67.2 BTB domain is critical to insulator function in Drosophila melanogaster. Molecular and cellular biology\| PubMed ID: 17101769	2007
Study of the functional interaction between Mcp insulators from the Drosophila bithorax complex: effects of insulator pairing on enhancer-promoter communication. Molecular and cellular biology\| PubMed ID: 17283051	2007
Evolutionarily conserved E(y)2/Sus1 protein is essential for the barrier activity of Su(Hw)-dependent insulators in Drosophila. Molecular cell\| PubMed ID: 17643381	2007
Long-distance interactions between regulatory elements are suppressed at the end of a terminally deficient chromosome in Drosophila melanogaster. Chromosoma\| PubMed ID: 17876596	2008
Characterization of Drosophila telomeric retroelement TAHRE: transcription, transpositions, and RNAi-based regulation of expression. Molecular biology and evolution\| PubMed ID: 17890237	2007
New properties of Drosophila fab-7 insulator. Genetics\| PubMed ID: 17890362	2007
Drosophila gypsy insulator and yellow enhancers regulate activity of yellow promoter through the same regulatory element. Chromosoma\| PubMed ID: 17994318	2008
Red flag on the white reporter: a versatile insulator abuts the white gene in Drosophila and is omnipresent in mini-white constructs. Nucleic acids research\| PubMed ID: 18086699	2008
'Insulator bodies' are aggregates of proteins but not of insulators. EMBO reports\| PubMed ID: 18369369	2008
Functional interaction between the Fab-7 and Fab-8 boundaries and the upstream promoter region in the Drosophila Abd-B gene. Molecular and cellular biology\| PubMed ID: 18426914	2008
Enhancer-promoter communication is regulated by insulator pairing in a Drosophila model bigenic locus. Molecular and cellular biology\| PubMed ID: 18573869	2008
Orientation-dependent interaction between Drosophila insulators is a property of this class of regulatory elements. Nucleic acids research\| PubMed ID: 18987002	2008
Zeste can facilitate long-range enhancer-promoter communication and insulator bypass in Drosophila melanogaster. Chromosoma\| PubMed ID: 19578867	2009
Drosophila mini-white model system: new insights into positive position effects and the role of transcriptional terminators and gypsy insulator in transgene shielding. Nucleic acids research\| PubMed ID: 19854952	2010
E(y)2/Sus1 is required for blocking PRE silencing by the Wari insulator in Drosophila melanogaster. Chromosoma\| PubMed ID: 20082086	2010
Interaction between a pair of gypsy insulators or between heterologous gypsy and Wari insulators modulates Flp site-specific recombination in Drosophila melanogaster. Chromosoma\| PubMed ID: 20354861	2010
Insulators, not Polycomb response elements, are required for long-range interactions between Polycomb targets in Drosophila melanogaster. Molecular and cellular biology\| PubMed ID: 21135119	2011
Selective interactions of boundaries with upstream region of Abd-B promoter in Drosophila bithorax complex and role of dCTCF in this process. Nucleic acids research\| PubMed ID: 21149269	2011
Drosophila BTB/POZ domains of "ttk group" can form multimers and selectively interact with each other. Journal of molecular biology\| PubMed ID: 21821048	2011
Insulators form gene loops by interacting with promoters in Drosophila. Development (Cambridge, England)\| PubMed ID: 21862564	2011
SUMO conjugation is required for the assembly of Drosophila Su(Hw) and Mod(mdg4) into insulator bodies that facilitate insulator complex formation. Journal of cell science\| PubMed ID: 22375064	2012
Insulator protein Su(Hw) recruits SAGA and Brahma complexes and constitutes part of Origin Recognition Complex-binding sites in the Drosophila genome. Nucleic acids research\| PubMed ID: 23609538	2013
New properties of Drosophila scs and scs' insulators. PloS one\| PubMed ID: 23638134	2013
Effective blocking of the white enhancer requires cooperation between two main mechanisms suggested for the insulator function. PLoS genetics\| PubMed ID: 23861668	2013
Chromatin insulators and long-distance interactions in Drosophila. FEBS letters\| PubMed ID: 24211836	2014
Making connections: insulators organize eukaryotic chromosomes into independent cis-regulatory networks. BioEssays : news and reviews in molecular, cellular and developmental biology\| PubMed ID: 24277632	2014
Transcription through enhancers suppresses their activity in Drosophila. Epigenetics & chromatin\| PubMed ID: 24279291	2013
Mechanisms and proteins involved in long-distance interactions. Frontiers in genetics\| PubMed ID: 24600469	2014
Highly conserved ENY2/Sus1 protein binds to Drosophila CTCF and is required for barrier activity. Epigenetics\| PubMed ID: 25147918	2014
Two new insulator proteins, Pita and ZIPIC, target CP190 to chromatin. Genome research\| PubMed ID: 25342723	2015
Eukaryotic enhancers: common features, regulation, and participation in diseases. Cellular and molecular life sciences : CMLS\| PubMed ID: 25715743	2015
The boundary paradox in the Bithorax complex. Mechanisms of development\| PubMed ID: 26215349	2015
Functional role of dimerization and CP190 interacting domains of CTCF protein in Drosophila melanogaster. BMC biology\| PubMed ID: 26248466	2015
EAST Organizes Drosophila Insulator Proteins in the Interchromosomal Nuclear Compartment and Modulates CP190 Binding to Chromatin. PloS one\| PubMed ID: 26489095	2015
Transcriptional read-through is not sufficient to induce an epigenetic switch in the silencing activity of Polycomb response elements. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26504232	2015
EAST affects the activity of Su(Hw) insulators by two different mechanisms in Drosophila melanogaster. Chromosoma\| PubMed ID: 27136940	2017
Architectural proteins Pita, Zw5,and ZIPIC contain homodimerization domain and support specific long-range interactions in Drosophila. Nucleic acids research\| PubMed ID: 27137890	2016
Transvection in Drosophila: trans-interaction between yellow enhancers and promoter is strongly suppressed by a cis-promoter only in certain genomic regions. Chromosoma\| PubMed ID: 27300555	2017
Functional Dissection of the Blocking and Bypass Activities of the Fab-8 Boundary in the Drosophila Bithorax Complex. PLoS genetics\| PubMed ID: 27428541	2016
Large-scale ATP-independent nucleosome unfolding by a histone chaperone. Nature structural & molecular biology\| PubMed ID: 27820806	2016
Boundaries of loop domains (insulators): Determinants of chromosome form and function in multicellular eukaryotes. BioEssays : news and reviews in molecular, cellular and developmental biology\| PubMed ID: 28133765	2017
The GAGA factor regulatory network: Identification of GAGA factor associated proteins. PloS one\| PubMed ID: 28296955	2017
Architectural protein Pita cooperates with dCTCF in organization of functional boundaries in Bithorax complex. Development (Cambridge, England)\| PubMed ID: 28619827	2017
Presenilin-1 Delta E9 Mutant Induces STIM1-Driven Store-Operated Calcium Channel Hyperactivation in Hippocampal Neurons. Molecular neurobiology\| PubMed ID: 28707074	2018
Interactions between BTB domain of CP190 and two adjacent regions in Su(Hw) are required for the insulator complex formation. Chromosoma\| PubMed ID: 28939920	2018
Multiple interactions are involved in a highly specific association of the Mod(mdg4)-67.2 isoform with the Su(Hw) sites in . Open biology\| PubMed ID: 29021216	2017
Opbp is a new architectural/insulator protein required for ribosomal gene expression. Nucleic acids research\| PubMed ID: 29036346	2017
Role of Su(Hw) zinc finger 10 and interaction with CP190 and Mod(mdg4) proteins in recruiting the Su(Hw) complex to chromatin sites in Drosophila. PloS one\| PubMed ID: 29474480	2018
The BEN Domain Protein Insensitive Binds to the Chromatin Boundary To Establish Proper Segmental Identity in . Genetics\| PubMed ID: 30082280	2018
Conserved sequences in the Drosophila mod(mdg4) intron promote poly(A)-independent transcription termination and trans-splicing. Nucleic acids research\| PubMed ID: 30102331	2018
The bithorax complex iab-7 Polycomb response element has a novel role in the functioning of the Fab-7 chromatin boundary. PLoS genetics\| PubMed ID: 30110328	2018
Boundaries mediate long-distance interactions between enhancers and promoters in the Drosophila Bithorax complex. PLoS genetics\| PubMed ID: 30540750	2018
Functional dissection of the developmentally restricted BEN domain chromatin boundary factor Insensitive. Epigenetics & chromatin\| PubMed ID: 30602385	2019
Transcription termination sequences support the expression of transgene product secreted with milk. Transgenic research\| PubMed ID: 30919251	2019
The same domain of Su(Hw) is required for enhancer blocking and direct promoter repression. Scientific reports\| PubMed ID: 30926937	2019
Removal of extra sequences with I-SceI in combination with CRISPR/Cas9 technique for precise gene editing in Drosophila. BioTechniques\| PubMed ID: 30987444	2019
Complete reconstitution of bypass and blocking functions in a minimal artificial insulator from complex. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 31209019	2019
The simultaneous interaction of MSL2 with CLAMP and DNA provides redundancy in the initiation of dosage compensation in males. Development (Cambridge, England)\| PubMed ID: 31320325	2019
Distinct Elements Confer the Blocking and Bypass Functions of the Bithorax Boundary. Genetics\| PubMed ID: 31551239	2019
Small Drosophila zinc finger C2H2 protein with an N-terminal zinc finger-associated domain demonstrates the architecture functions. Biochimica et biophysica acta. Gene regulatory mechanisms\| PubMed ID: 31706027	2020
HIPP1 stabilizes the interaction between CP190 and Su(Hw) in the Drosophila insulator complex. Scientific reports\| PubMed ID: 31836797	2019
N-terminal domain of the architectural protein CTCF has similar structural organization and ability to self-association in bilaterian organisms. Scientific reports\| PubMed ID: 32060375	2020
The insulator functions of the polydactyl C2H2 zinc finger protein CTCF: Necessity versus sufficiency. Science advances\| PubMed ID: 32232161	2020
Mechanisms of Enhancer-Promoter Interactions in Higher Eukaryotes. International journal of molecular sciences\| PubMed ID: 33445415	2021
Mapping of functional elements of the Fab-6 boundary involved in the regulation of the Abd-B hox gene in Drosophila melanogaster. Scientific reports\| PubMed ID: 33603202	2021
A Non-stop identity complex (NIC) supervises enterocyte identity and protects from premature aging. eLife\| PubMed ID: 33629655	2021
Structural basis of diversity and homodimerization specificity of zinc-finger-associated domains in Drosophila. Nucleic acids research\| PubMed ID: 33638995	2021
Mechanism and functional role of the interaction between CP190 and the architectural protein Pita in Drosophila melanogaster. Epigenetics & chromatin\| PubMed ID: 33752739	2021
Boundaries potentiate polycomb response element-mediated silencing. BMC biology\| PubMed ID: 34078365	2021
Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types. Cancers\| PubMed ID: 34202528	2021
Drosophila architectural protein CTCF is not essential for fly survival and is able to function independently of CP190. Biochimica et biophysica acta. Gene regulatory mechanisms\| PubMed ID: 34311130	2021
Redundant enhancers in the iab-5 domain cooperatively activate Abd-B in the A5 and A6 abdominal segments of Drosophila. Development (Cambridge, England)\| PubMed ID: 34473267	2021
Mechanisms of CP190 Interaction with Architectural Proteins in Drosophila Melanogaster. International journal of molecular sciences\| PubMed ID: 34830280	2021
Dimerization Activity of a Disordered N-Terminal Domain from CLAMP Protein. International journal of molecular sciences\| PubMed ID: 35409222	2022
Structural insights into highly similar spatial organization of zinc-finger associated domains with a very low sequence similarity. Structure (London, England : 1993)\| PubMed ID: 35580610	2022
Comparative interactome analysis of the PRE DNA-binding factors: purification of the Combgap-, Zeste-, Psq-, and Adf1-associated proteins. Cellular and molecular life sciences : CMLS\| PubMed ID: 35676368	2022
Structure of the DNMT3B ADD domain suggests the absence of a DNMT3A-like autoinhibitory mechanism. Biochemical and biophysical research communications\| PubMed ID: 35760008	2022
BTB domains: A structural view of evolution, multimerization, and protein-protein interactions. BioEssays : news and reviews in molecular, cellular and developmental biology\| PubMed ID: 36449605	2022
Mechanisms of enhancer-promoter communication and chromosomal architecture in mammals and . Frontiers in genetics\| PubMed ID: 36531247	2022