David R. Hinton

USC Dr. Allen and Charlotte Ginsburg Institute for Biomedical Therapeutics, University of Southern California

Affiliated withUniversity of Southern California Keck School of Medicine of the University of Southern California

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2022

Other Publications

Article	Year
Contributions of Fas-Fas ligand interactions to the pathogenesis of mouse hepatitis virus in the central nervous system. Journal of virology\| PubMed ID: 10666278	2000
Kinetics of cytokine mRNA expression in the central nervous system following lethal and nonlethal coronavirus-induced acute encephalomyelitis. Virology\| PubMed ID: 9217050	1997
Expression of interferon-gamma by a coronavirus defective-interfering RNA vector and its effect on viral replication, spread, and pathogenicity. Virology\| PubMed ID: 9217056	1997
Expression of hemagglutinin/esterase by a mouse hepatitis virus coronavirus defective-interfering RNA alters viral pathogenesis. Virology\| PubMed ID: 9501044	1998
Transgenic interleukin 10 prevents induction of experimental autoimmune encephalomyelitis. The Journal of experimental medicine\| PubMed ID: 10075984	1999
Viral induced demyelination. Brain pathology (Zurich, Switzerland)\| PubMed ID: 11145206	2001
Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants. Current biology : CB\| PubMed ID: 11882291	2002
Matrix metalloproteinase expression correlates with virulence following neurotropic mouse hepatitis virus infection. Journal of virology\| PubMed ID: 12097550	2002
Regulation of RPE intercellular junction integrity and function by hepatocyte growth factor. Investigative ophthalmology & visual science\| PubMed ID: 12147616	2002
The art of survival during viral persistence. Journal of neurovirology\| PubMed ID: 12491152	2002
Neutrophils promote mononuclear cell infiltration during viral-induced encephalitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12626593	2003
A role for connective tissue growth factor in the pathogenesis of choroidal neovascularization. Archives of ophthalmology (Chicago, Ill. : 1960)\| PubMed ID: 12963611	2003
Developmental retinal apoptosis in Ku86-/- mice. DNA repair\| PubMed ID: 14642570	2003
Hepatocyte growth factor and its role in the pathogenesis of retinal detachment. Investigative ophthalmology & visual science\| PubMed ID: 14691191	2004
Mouse strain-dependent heterogeneity of resting limbal vasculature. Investigative ophthalmology & visual science\| PubMed ID: 14744883	2004
Perforin and gamma interferon-mediated control of coronavirus central nervous system infection by CD8 T cells in the absence of CD4 T cells. Journal of virology\| PubMed ID: 14747539	2004
Accumulation of NH2-terminal fragment of connective tissue growth factor in the vitreous of patients with proliferative diabetic retinopathy. Diabetes care\| PubMed ID: 14988298	2004
Gene therapy in a murine model for clinical application to multiple sclerosis. Annals of neurology\| PubMed ID: 14991817	2004
Ceramide-induced apoptosis: role of catalase and hepatocyte growth factor. Free radical biology & medicine\| PubMed ID: 15203188	2004
Differential regulation of primary and secondary CD8+ T cells in the central nervous system. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15528365	2004
Expression of a dominant negative IFN-gammareceptor on mouse oligodendrocytes. Glia\| PubMed ID: 15779088	2005
Expression of matrix metalloproteinases and their tissue inhibitor during viral encephalitis. Journal of virology\| PubMed ID: 15795262	2005
Maintenance of CD8+ T cells during acute viral infection of the central nervous system requires CD4+ T cells but not interleukin-2. Viral immunology\| PubMed ID: 15802960	2005
Differential expression of pro- and antiangiogenic factors in mouse strain-dependent hypoxia-induced retinal neovascularization. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 15856049	2005
A selective cyclic integrin antagonist blocks the integrin receptors alphavbeta3 and alphavbeta5 and inhibits retinal pigment epithelium cell attachment, migration and invasion. BMC ophthalmology\| PubMed ID: 15987521	2005
Neutrophils promote experimental choroidal neovascularization. Molecular vision\| PubMed ID: 15988410	2005
Protection from oxidative stress by methionine sulfoxide reductases in RPE cells. Biochemical and biophysical research communications\| PubMed ID: 15993845	2005
Astrocyte expression of a dominant-negative interferon-gamma receptor. Journal of neuroscience research\| PubMed ID: 16118798	2005
In vivo expression of GFP transgene delivered via a replicating feline leukemia virus. Veterinary microbiology\| PubMed ID: 16143471	2005
Sequential induction of angiogenic growth factors by TNF-alpha in choroidal endothelial cells. Journal of neuroimmunology\| PubMed ID: 16288810	2006
Soluble EphB4 regulates choroidal endothelial cell function and inhibits laser-induced choroidal neovascularization. Investigative ophthalmology & visual science\| PubMed ID: 16303978	2005
Neuropilin-1 expression by endothelial cells and retinal pigment epithelial cells in choroidal neovascular membranes. American journal of ophthalmology\| PubMed ID: 16376649	2005
Characterization of brimonidine transport in retinal pigment epithelium. Investigative ophthalmology & visual science\| PubMed ID: 16384975	2006
CNS viral infection diverts homing of antibody-secreting cells from lymphoid organs to the CNS. European journal of immunology\| PubMed ID: 16437540	2006
Inhibition of interferon-gamma signaling in oligodendroglia delays coronavirus clearance without altering demyelination. The American journal of pathology\| PubMed ID: 16507895	2006
Mouse hepatitis virus pathogenesis in the central nervous system is independent of IL-15 and natural killer cells. Virology\| PubMed ID: 16510164	2006
Transforming growth factor beta2-induced myofibroblastic differentiation of human retinal pigment epithelial cells: regulation by extracellular matrix proteins and hepatocyte growth factor. Experimental eye research\| PubMed ID: 16563380	2006
MMP-2 and MMP-9 secretion by rpe is stimulated by angiogenic molecules found in choroidal neovascular membranes. Retina (Philadelphia, Pa.)\| PubMed ID: 16603966	2006
Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina. The American journal of pathology\| PubMed ID: 16651637	2006
Thiol regulation of vascular endothelial growth factor-A and its receptors in human retinal pigment epithelial cells. Biochemical and biophysical research communications\| PubMed ID: 16793007	2006
Altered neuroantigen-specific cytokine secretion in a Th2 environment reduces experimental autoimmune encephalomyelitis. Journal of neuroimmunology\| PubMed ID: 16814872	2006
Liver X receptor activation decreases the severity of experimental autoimmune encephalomyelitis. Journal of neuroscience research\| PubMed ID: 16955483	2006
Population-based study of early age-related macular degeneration: role of the complement factor H Y402H polymorphism in bilateral but not unilateral disease. Ophthalmology\| PubMed ID: 17198853	2007
Stimulation of apical and basolateral VEGF-A and VEGF-C secretion by oxidative stress in polarized retinal pigment epithelial cells. Molecular vision\| PubMed ID: 17200665	2006
Thrombospondin-1 expression in RPE and choroidal neovascular membranes. Yan ke xue bao = Eye science\| PubMed ID: 17378161	2006
In vivo models of proliferative vitreoretinopathy. Nature protocols\| PubMed ID: 17401340	2007
alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress. Molecular vision\| PubMed ID: 17438522	2007
Type I interferons are essential in controlling neurotropic coronavirus infection irrespective of functional CD8 T cells. Journal of virology\| PubMed ID: 17928334	2008
CD4 T cells contribute to virus control and pathology following central nervous system infection with neurotropic mouse hepatitis virus. Journal of virology\| PubMed ID: 18094171	2008
Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia. Experimental eye research\| PubMed ID: 18191123	2008
Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie\| PubMed ID: 18278507	2008
N-(4-hydroxyphenyl) retinamide augments laser-induced choroidal neovascularization in mice. Investigative ophthalmology & visual science\| PubMed ID: 18326751	2008
Connective tissue growth factor as a mediator of intraocular fibrosis. Investigative ophthalmology & visual science\| PubMed ID: 18450591	2008
The immune response to herpes simplex virus type 1 infection in susceptible mice is a major cause of central nervous system pathology resulting in fatal encephalitis. Journal of virology\| PubMed ID: 18480436	2008
Paclitaxel Induces Apoptosis in AIDS-Related Kaposi's Sarcoma Cells. Sarcoma\| PubMed ID: 18521433	2000
Toll-like receptor 3 and geographic atrophy in age-related macular degeneration. The New England journal of medicine\| PubMed ID: 18753640	2008
Memory CD4+ T-cell-mediated protection from lethal coronavirus encephalomyelitis. Journal of virology\| PubMed ID: 18842712	2008
Regulation of thioredoxin by ceramide in retinal pigment epithelial cells. Experimental eye research\| PubMed ID: 18996115	2009
Immunocytochemical analysis of retinal neurons under electrical stimulation. Brain research\| PubMed ID: 19103179	2009
BMP4 mediates oxidative stress-induced retinal pigment epithelial cell senescence and is overexpressed in age-related macular degeneration. The Journal of biological chemistry\| PubMed ID: 19158083	2009
Regulated secretion of complement factor H by RPE and its role in RPE migration. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie\| PubMed ID: 19214553	2009
A protocol for the culture and differentiation of highly polarized human retinal pigment epithelial cells. Nature protocols\| PubMed ID: 19373231	2009
Identification of a novel sodium-coupled oligopeptide transporter (SOPT2) in mouse and human retinal pigment epithelial cells. Investigative ophthalmology & visual science\| PubMed ID: 19643969	2010
Soluble EphB4 inhibition of PDGF-induced RPE migration in vitro. Investigative ophthalmology & visual science\| PubMed ID: 19696168	2010
Expression and regulation of enzymes in the ceramide metabolic pathway in human retinal pigment epithelial cells and their relevance to retinal degeneration. Vision research\| PubMed ID: 19765607	2010
RNase L mediated protection from virus induced demyelination. PLoS pathogens\| PubMed ID: 19798426	2009
Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis. Cell death and differentiation\| PubMed ID: 19816510	2010
alphaB-crystallin regulation of angiogenesis by modulation of VEGF. Blood\| PubMed ID: 20023214	2010
Gamma interferon signaling in oligodendrocytes is critical for protection from neurotropic coronavirus infection. Journal of virology\| PubMed ID: 20042510	2010
What determines the switch between atrophic and neovascular forms of age related macular degeneration? - the role of BMP4 induced senescence. Aging\| PubMed ID: 20157553	2009
Neutrophils compromise retinal pigment epithelial barrier integrity. Journal of biomedicine & biotechnology\| PubMed ID: 20204129	2010
Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: relevance to age-related macular degeneration. Aging\| PubMed ID: 20228934	2009
Recombinant human VEGF165b inhibits experimental choroidal neovascularization. Investigative ophthalmology & visual science\| PubMed ID: 20237252	2010
Enhanced antiviral T cell function in the absence of B7-H1 is insufficient to prevent persistence but exacerbates axonal bystander damage during viral encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20876353	2010
Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: possible role of reactive oxygen species. Journal of neuroscience research\| PubMed ID: 20936703	2010
αB crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells. PloS one\| PubMed ID: 20949024	2010
Grp78 heterozygosity regulates chaperone balance in exocrine pancreas with differential response to cerulein-induced acute pancreatitis. The American journal of pathology\| PubMed ID: 20971738	2010
Vitreal oxygenation in retinal ischemia reperfusion. Investigative ophthalmology & visual science\| PubMed ID: 21051734	2011
Polarized secretion of PEDF from human embryonic stem cell-derived RPE promotes retinal progenitor cell survival. Investigative ophthalmology & visual science\| PubMed ID: 21087957	2011
Factors supporting intrathecal humoral responses following viral encephalomyelitis. Journal of virology\| PubMed ID: 21191015	2011
Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis. Biochemical and biophysical research communications\| PubMed ID: 21219868	2011
Sonoporation enhances chemotherapeutic efficacy in retinoblastoma cells in vitro. Investigative ophthalmology & visual science\| PubMed ID: 21273549	2011
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature\| PubMed ID: 21297615	2011
Antenatal maternal stress alters functional brain responses in adult offspring during conditioned fear. Brain research\| PubMed ID: 21300034	2011
Transcriptional regulation of bone morphogenetic protein 4 by tumor necrosis factor and its relationship with age-related macular degeneration. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 21411747	2011
CXCR3-dependent plasma blast migration to the central nervous system during viral encephalomyelitis. Journal of virology\| PubMed ID: 21507985	2011
Shifting hierarchies of interleukin-10-producing T cell populations in the central nervous system during acute and persistent viral encephalomyelitis. Journal of virology\| PubMed ID: 21525347	2011
Regulation of fibronectin-EDA through CTGF domain-specific interactions with TGFβ2 and its receptor TGFβRII. Investigative ophthalmology & visual science\| PubMed ID: 21571675	2011
Methionine sulfoxide reductase A: Structure, function and role in ocular pathology. World journal of biological chemistry\| PubMed ID: 21909460	2011
VEGF and PEDF secretion in ARPE-19 and fhRPE cells. Investigative ophthalmology & visual science\| PubMed ID: 22104197	2011
WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing. Cancer cell\| PubMed ID: 22172722	2011
CD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitis. Journal of virology\| PubMed ID: 22205741	2012
Over-expression of BMP4 inhibits experimental choroidal neovascularization by modulating VEGF and MMP-9. Angiogenesis\| PubMed ID: 22392094	2012
Mechanism of RPE cell death in α-crystallin deficient mice: a novel and critical role for MRP1-mediated GSH efflux. PloS one\| PubMed ID: 22442691	2012
DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell\| PubMed ID: 22541070	2012
IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils. Journal of neuroinflammation\| PubMed ID: 22642802	2012
Novel roles for α-crystallins in retinal function and disease. Progress in retinal and eye research\| PubMed ID: 22721717	2012
Deficiency of αB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunction. Free radical biology & medicine\| PubMed ID: 22781655	2012
IFN-γ signaling to astrocytes protects from autoimmune mediated neurological disability. PloS one\| PubMed ID: 22848713	2012
A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic research\| PubMed ID: 22868580	2012
ERK1/2 activation is a therapeutic target in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22869729	2012
Green tea polyphenols precondition against cell death induced by oxygen-glucose deprivation via stimulation of laminin receptor, generation of reactive oxygen species, and activation of prot... The Journal of biological chemistry\| PubMed ID: 22879598	2012
Angiofibrotic response to vascular endothelial growth factor inhibition in diabetic retinal detachment: report no. 1. Archives of ophthalmology (Chicago, Ill. : 1960)\| PubMed ID: 22965588	2012
GRP78 plays an essential role in adipogenesis and postnatal growth in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 23180827	2013
Enhanced CD8 T-cell anti-viral function and clinical disease in B7-H1-deficient mice requires CD4 T cells during encephalomyelitis. Journal of neuroinflammation\| PubMed ID: 23237504	2012
Astrocyte-derived CXCL10 drives accumulation of antibody-secreting cells in the central nervous system during viral encephalomyelitis. Journal of virology\| PubMed ID: 23302888	2013
Antiapoptotic properties of α-crystallin-derived peptide chaperones and characterization of their uptake transporters in human RPE cells. Investigative ophthalmology & visual science\| PubMed ID: 23532520	2013
Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer. Investigative ophthalmology & visual science\| PubMed ID: 23833067	2013
IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis. Journal of neuroimmunology\| PubMed ID: 23992866	2013
TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophy. Investigative ophthalmology & visual science\| PubMed ID: 24114535	2013
MMP-independent role of TIMP-1 at the blood brain barrier during viral encephalomyelitis. ASN neuro\| PubMed ID: 24156369	2013
Ifit2 deficiency results in uncontrolled neurotropic coronavirus replication and enhanced encephalitis via impaired alpha/beta interferon induction in macrophages. Journal of virology\| PubMed ID: 24198415	2014
Role of CD25(+) CD4(+) T cells in acute and persistent coronavirus infection of the central nervous system. Virology\| PubMed ID: 24210105	2013
PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis. Journal of neuroimmunology\| PubMed ID: 24642385	2014
Ceramide inhibits connective tissue growth factor expression by human retinal pigment epithelial cells. Cytokine\| PubMed ID: 24758915	2014
Protein polymer nanoparticles engineered as chaperones protect against apoptosis in human retinal pigment epithelial cells. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 24780268	2014
Protection of retina by αB crystallin in sodium iodate induced retinal degeneration. PloS one\| PubMed ID: 24874187	2014
IL-27 limits central nervous system viral clearance by promoting IL-10 and enhances demyelination. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24890725	2014
Distinct CD4 T-cell effects on primary versus recall CD8 T-cell responses during viral encephalomyelitis. Immunology\| PubMed ID: 25187405	2015
DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25349431	2014
Pharmacological protection of retinal pigmented epithelial cells by sulindac involves PPAR-α. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25385631	2014
Polarized human embryonic stem cell-derived retinal pigment epithelial cell monolayers have higher resistance to oxidative stress-induced cell death than nonpolarized cultures. Stem cells translational medicine\| PubMed ID: 25411476	2015
Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity. Science (New York, N.Y.)\| PubMed ID: 25414314	2014
IL-18 is not therapeutic for neovascular age-related macular degeneration. Nature medicine\| PubMed ID: 25473914	2014
TGF-β2 secretion from RPE decreases with polarization and becomes apically oriented. Cytokine\| PubMed ID: 25496702	2015
Sodium iodate induced retinal degeneration: new insights from an old model. Neural regeneration research\| PubMed ID: 25657718	2014
Molecular mechanisms of subretinal fibrosis in age-related macular degeneration. Experimental eye research\| PubMed ID: 25773985	2016
Attenuation of choroidal neovascularization by histone deacetylase inhibitor. PloS one\| PubMed ID: 25807249	2015
Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis. Journal of neuroinflammation\| PubMed ID: 25896970	2015
Alpha crystallins in the retinal pigment epithelium and implications for the pathogenesis and treatment of age-related macular degeneration. Biochimica et biophysica acta\| PubMed ID: 26026469	2016
Stem cell based therapies for age-related macular degeneration: The promises and the challenges. Progress in retinal and eye research\| PubMed ID: 26113213	2015
Interleukin-10 is a critical regulator of white matter lesion containment following viral induced demyelination. Glia\| PubMed ID: 26132901	2015
Myd88 Initiates Early Innate Immune Responses and Promotes CD4 T Cells during Coronavirus Encephalomyelitis. Journal of virology\| PubMed ID: 26136579	2015
SIRT1 mediated inhibition of VEGF/VEGFR2 signaling by Resveratrol and its relevance to choroidal neovascularization. Cytokine\| PubMed ID: 26174951	2015
Inhibition of DNA Methylation and Methyl-CpG-Binding Protein 2 Suppresses RPE Transdifferentiation: Relevance to Proliferative Vitreoretinopathy. Investigative ophthalmology & visual science\| PubMed ID: 26305530	2015
Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathy. Scientific reports\| PubMed ID: 26552368	2015
Aqueous Angiography: Real-Time and Physiologic Aqueous Humor Outflow Imaging. PloS one\| PubMed ID: 26807586	2016
αB-Crystallin Regulates Subretinal Fibrosis by Modulation of Epithelial-Mesenchymal Transition. The American journal of pathology\| PubMed ID: 26878210	2016
Sustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis. Journal of neuroinflammation\| PubMed ID: 26906225	2016
The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction. Investigative ophthalmology & visual science\| PubMed ID: 26990160	2016
Targeting of exon VI-skipping human RGR-opsin to the plasma membrane of pigment epithelium and co-localization with terminal complement complex C5b-9. Molecular vision\| PubMed ID: 27011730	2016
Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats. Investigative ophthalmology & visual science\| PubMed ID: 27233037	2016
Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie\| PubMed ID: 27335025	2016
Aqueous Angiography-Mediated Guidance of Trabecular Bypass Improves Angiographic Outflow in Human Enucleated Eyes. Investigative ophthalmology & visual science\| PubMed ID: 27588614	2016
Differential Regulation of Self-reactive CD4 T Cells in Cervical Lymph Nodes and Central Nervous System during Viral Encephalomyelitis. Frontiers in immunology\| PubMed ID: 27708643	2016
Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione. PloS one\| PubMed ID: 27783653	2016
Aqueous Angiography with Fluorescein and Indocyanine Green in Bovine Eyes. Translational vision science & technology\| PubMed ID: 27847692	2016
Endoplasmic reticulum-mitochondrial crosstalk: a novel role for the mitochondrial peptide humanin. Neural regeneration research\| PubMed ID: 28250736	2017
Retinal amyloid pathology and proof-of-concept imaging trial in Alzheimer's disease. JCI insight\| PubMed ID: 28814675	2017
Protective Mechanisms of the Mitochondrial-Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells. Oxidative medicine and cellular longevity\| PubMed ID: 28814984	2017
Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models. Stem cells international\| PubMed ID: 28928775	2017
Development of a new tissue injector for subretinal transplantation of human embryonic stem cell derived retinal pigmented epithelium. International journal of retina and vitreous\| PubMed ID: 29093829	2017
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration. Nature medicine\| PubMed ID: 29176737	2018
APOPTOSIS AND ANGIOFIBROSIS IN DIABETIC TRACTIONAL MEMBRANES AFTER VASCULAR ENDOTHELIAL GROWTH FACTOR INHIBITION: Results of a Prospective Trial. Report No. 2. Retina (Philadelphia, Pa.)\| PubMed ID: 29190236	2019
A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration. Science translational medicine\| PubMed ID: 29618560	2018
Intra-vitreal αB crystallin fused to elastin-like polypeptide provides neuroprotection in a mouse model of age-related macular degeneration. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 29778783	2018
Mechanism of cytokinesis failure in ovarian cystadenomas with defective BRCA1 and P53 pathways. International journal of cancer\| PubMed ID: 29978915	2018
A new immunodeficient retinal dystrophic rat model for transplantation studies using human-derived cells. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie\| PubMed ID: 30215097	2018
Characterization and Regulation of Carrier Proteins of Mitochondrial Glutathione Uptake in Human Retinal Pigment Epithelium Cells. Investigative ophthalmology & visual science\| PubMed ID: 30707752	2019
Histopathologic Assessment of Optic Nerves and Retina From a Patient With Chronically Implanted Argus II Retinal Prosthesis System. Translational vision science & technology\| PubMed ID: 31171998	2019
A Novel HDL-Mimetic Peptide HM-10/10 Protects RPE and Photoreceptors in Murine Models of Retinal Degeneration. International journal of molecular sciences\| PubMed ID: 31569695	2019
Sympathetic Effects of Internal Carotid Nerve Manipulation on Choroidal Vascularity and Related Measures. Investigative ophthalmology & visual science\| PubMed ID: 31618767	2019
The humanin peptide mediates ELP nanoassembly and protects human retinal pigment epithelial cells from oxidative stress. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 31655204	2020
Surgical Method for Implantation of a Biosynthetic Retinal Pigment Epithelium Monolayer for Geographic Atrophy: Experience from a Phase 1/2a Study. Ophthalmology. Retina\| PubMed ID: 31786135	2020
Identification of early pericyte loss and vascular amyloidosis in Alzheimer's disease retina. Acta neuropathologica\| PubMed ID: 32043162	2020
The Emerging Role of Senescence in Ocular Disease. Oxidative medicine and cellular longevity\| PubMed ID: 32215170	2020
Cytoplasmic synthesis of endogenous complementary DNA via reverse transcription and implications in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 33526699	2021
Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo. Scientific reports\| PubMed ID: 33737600	2021
complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity. Science advances\| PubMed ID: 34586848	2021
One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration. Translational vision science & technology\| PubMed ID: 34613357	2021
Long-Term Transplant Effects of iPSC-RPE Monolayer in Immunodeficient RCS Rats. Cells\| PubMed ID: 34831174	2021
DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs. Science immunology\| PubMed ID: 34860583	2021
Mechanisms of RPE senescence and potential role of αB crystallin peptide as a senolytic agent in experimental AMD. Experimental eye research\| PubMed ID: 34986369	2022
Blocking Ocular Sympathetic Activity Inhibits Choroidal Neovascularization. Frontiers in neuroscience\| PubMed ID: 35082594	2021
Survival of an HLA-mismatched, bioengineered RPE implant in dry age-related macular degeneration. Stem cell reports\| PubMed ID: 35120620	2022