Hiroshi Nakagawa

Herbert Irving Comprehensive Cancer Center, Columbia University

Affiliated withColumbia University Columbia College

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 10	2022

Other Publications

Article	Year
Optical imaging of periostin enables early endoscopic detection and characterization of esophageal cancer in mice. Gastroenterology\| PubMed ID: 23085486	2013
Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4. Cell cycle (Georgetown, Tex.)\| PubMed ID: 25558829	2014
Immature myeloid progenitors promote disease progression in a mouse model of Barrett's-like metaplasia. Oncotarget\| PubMed ID: 26460825	2015
Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis. Gut\| PubMed ID: 26884425	2017
Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration. The Journal of clinical investigation\| PubMed ID: 28481227	2017
Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma. Nature communications\| PubMed ID: 29170450	2017
Persistent Basal Cell Hyperplasia Is Associated With Clinical and Endoscopic Findings in Patients With Histologically Inactive Eosinophilic Esophagitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 31499251	2020
Esophageal 3D organoids of mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition. Oncotarget\| PubMed ID: 31692873	2019
Use of hPSC-derived 3D organoids and mouse genetics to define the roles of YAP in the development of the esophagus. Development (Cambridge, England)\| PubMed ID: 31748205	2019
Outcomes of patients with submucosal (T1b) esophageal adenocarcinoma: a multicenter cohort study. Gastrointestinal endoscopy\| PubMed ID: 31953189	2020
Modeling Epithelial Homeostasis and Reactive Epithelial Changes in Human and Murine Three-Dimensional Esophageal Organoids. Current protocols in stem cell biology\| PubMed ID: 32105412	2020
Generation and Characterization of Patient-Derived Head and Neck, Oral, and Esophageal Cancer Organoids. Current protocols in stem cell biology\| PubMed ID: 32294323	2020
Notch Signaling Mediates Differentiation in Barrett's Esophagus and Promotes Progression to Adenocarcinoma. Gastroenterology\| PubMed ID: 32325086	2020
Olig2-Induced Semaphorin Expression Drives Corticospinal Axon Retraction After Spinal Cord Injury. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 32564090	2020
Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes. PloS one\| PubMed ID: 32966340	2020
Mitochondrial dysfunction in inflammatory bowel disease alters intestinal epithelial metabolism of hepatic acylcarnitines. The Journal of clinical investigation\| PubMed ID: 33141762	2021
Rab11-FIP1 mediates epithelial-mesenchymal transition and invasion in esophageal cancer. EMBO reports\| PubMed ID: 33403789	2021
MicroRNA-Based Cancer Mortality Risk Scoring System and hTERT Expression in Early-Stage Oral Squamous Cell Carcinoma. Journal of oncology\| PubMed ID: 33510789	2021
Mutant p53 regulates Survivin to foster lung metastasis. Genes & development\| PubMed ID: 33737385	2021
Pan-ERBB kinase inhibition augments CDK4/6 inhibitor efficacy in oesophageal squamous cell carcinoma. Gut\| PubMed ID: 33789967	2022
Understanding the cellular origin and progression of esophageal cancer using esophageal organoids. Cancer letters\| PubMed ID: 33838281	2021
Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence. Nature genetics\| PubMed ID: 33972779	2021
NOTCH3 limits the epithelial-mesenchymal transition and predicts a favorable clinical outcome in esophageal cancer. Cancer medicine\| PubMed ID: 34042293	2021
Stem cells and origins of cancer in the upper gastrointestinal tract. Cell stem cell\| PubMed ID: 34129814	2021
FANCD2 limits acetaldehyde-induced genomic instability during DNA replication in esophageal keratinocytes. Molecular oncology\| PubMed ID: 34328261	2021
Alcohol Metabolism Enriches Squamous Cell Carcinoma Cancer Stem Cells That Survive Oxidative Stress via Autophagy. Biomolecules\| PubMed ID: 34680112	2021
Patient-derived organoids as a platform for modeling a patient's response to chemoradiotherapy in esophageal cancer. Scientific reports\| PubMed ID: 34716381	2021
3D Organoids: An Untapped Platform for Studying Host-Microbiome Interactions in Esophageal Cancers. Microorganisms\| PubMed ID: 34835308	2021
CD73 Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 35108658	2022
Detergent exposure induces epithelial barrier dysfunction and eosinophilic inflammation in the esophagus. Allergy\| PubMed ID: 35899466	2022
HPV E6 regulates therapy responses in oropharyngeal cancer by repressing the PGC-1α/ERRα axis. JCI insight\| PubMed ID: 36134662	2022
Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation. Nature communications\| PubMed ID: 36329064	2022