Wen Bu

Lester & Sue Smith Breast Center, Baylor College of Medicine

Affiliated withBaylor College of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2023

Other Publications

Article	Year
Keratin 6 is not essential for mammary gland development. Breast cancer research : BCR\| PubMed ID: 16790075	2006
Lentivirus-mediated oncogene introduction into mammary cells in vivo induces tumors. Neoplasia (New York, N.Y.)\| PubMed ID: 18592025	2008
Lentivirus vectors for stably introducing genes into mammary epithelial cells in vivo. Journal of mammary gland biology and neoplasia\| PubMed ID: 19936990	2009
Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20133707	2010
Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer. Oncogene\| PubMed ID: 21532625	2011
EGFR-induced and PKCε monoubiquitylation-dependent NF-κB activation upregulates PKM2 expression and promotes tumorigenesis. Molecular cell\| PubMed ID: 23123196	2012
A novel role of hematopoietic CCL5 in promoting triple-negative mammary tumor progression by regulating generation of myeloid-derived suppressor cells. Cell research\| PubMed ID: 23266888	2013
Differential regulation of c-Jun protein plays an instrumental role in chemoresistance of cancer cells. The Journal of biological chemistry\| PubMed ID: 23678002	2013
Amplification and over-expression of MAP3K3 gene in human breast cancer promotes formation and survival of breast cancer cells. The Journal of pathology\| PubMed ID: 24122835	2014
Mammary cells with active Wnt signaling resist ErbB2-induced tumorigenesis. PloS one\| PubMed ID: 24265712	2013
Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer. Stem cells translational medicine\| PubMed ID: 24797826	2014
STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer. Stem cells (Dayton, Ohio)\| PubMed ID: 24891218	2014
Krt6a-positive mammary epithelial progenitors are not at increased vulnerability to tumorigenesis initiated by ErbB2. PloS one\| PubMed ID: 25635772	2015
Luminal epithelial cells within the mammary gland can produce basal cells upon oncogenic stress. Oncogene\| PubMed ID: 26096929	2016
Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation. Cell reports\| PubMed ID: 26166574	2015
Targeting Oncogenes into a Defined Subset of Mammary Cells Demonstrates That the Initiating Oncogenic Mutation Defines the Resulting Tumor Phenotype. International journal of biological sciences\| PubMed ID: 27019623	2016
Breast tumor cell-specific knockout of inhibits cancer cell plasticity, dissemination, and lung metastasis in mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 29073077	2017
Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. The Journal of clinical investigation\| PubMed ID: 29480818	2018
Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes. Cancer research\| PubMed ID: 30401712	2019
Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms. Nature cell biology\| PubMed ID: 31451770	2019
Intraductal Injection of Lentivirus Vectors for Stably Introducing Genes into Rat Mammary Epithelial Cells in Vivo. Journal of mammary gland biology and neoplasia\| PubMed ID: 33165800	2020
Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 34667127	2022
High-throughput profiling of histone post-translational modifications and chromatin modifying proteins by reverse phase protein array. Journal of proteomics\| PubMed ID: 35489683	2022
Short-term PI3K Inhibition Prevents Breast Cancer in Preclinical Models. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 36343340	2023