Michel C. Nussenzweig

Laboratory of Molecular Immunology, The Rockefeller University

Affiliated withThe Rockefeller University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 12	2023

Other Publications

Article	Year
Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell\| PubMed ID: 26004070	2015
Differential regulation of self-reactivity discriminates between IgG+ human circulating memory B cells and bone marrow plasma cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22025722	2011
Translocation capture sequencing: a method for high throughput mapping of chromosomal rearrangements. Journal of immunological methods\| PubMed ID: 22033343	2012
Polyreactive antibodies in adaptive immune responses to viruses. Cellular and molecular life sciences : CMLS\| PubMed ID: 22045557	2012
Enhanced HIV-1 neutralization by antibody heteroligation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22219363	2012
Activation-induced cytidine deaminase in antibody diversification and chromosome translocation. Advances in cancer research\| PubMed ID: 22429855	2012
Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage. The Journal of experimental medicine\| PubMed ID: 22615130	2012
Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein. The Journal of experimental medicine\| PubMed ID: 22826297	2012
Zinc finger transcription factor zDC is a negative regulator required to prevent activation of classical dendritic cells in the steady state. The Journal of experimental medicine\| PubMed ID: 22851594	2012
The hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo. The EMBO journal\| PubMed ID: 22940690	2012
Chromosome translocation, B cell lymphoma, and activation-induced cytidine deaminase. Annual review of pathology\| PubMed ID: 22974238	2013
DEC-205 is a cell surface receptor for CpG oligonucleotides. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22988114	2012
The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry. Nature immunology\| PubMed ID: 23001145	2012
A mouse model for HIV-1 entry. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23019371	2012
A Blueprint for HIV Vaccine Discovery. Cell host & microbe\| PubMed ID: 23084910	2012
HIV therapy by a combination of broadly neutralizing antibodies in humanized mice. Nature\| PubMed ID: 23103874	2012
Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23115339	2012
Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching. The Journal of experimental medicine\| PubMed ID: 23254285	2013
RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycle. Cell reports\| PubMed ID: 23291097	2013
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching. Science (New York, N.Y.)\| PubMed ID: 23306439	2013
Role of 53BP1 oligomerization in regulating double-strand break repair. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23345425	2013
Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23524883	2013
Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization. Cell\| PubMed ID: 23540694	2013
Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection. Nature medicine\| PubMed ID: 23685841	2013
Restricting HIV-1 pathways for escape using rationally designed anti-HIV-1 antibodies. The Journal of experimental medicine\| PubMed ID: 23712429	2013
High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration. Journal of virology\| PubMed ID: 23720718	2013
Antibody and antiretroviral preexposure prophylaxis prevent cervicovaginal HIV-1 infection in a transgenic mouse model. Journal of virology\| PubMed ID: 23720722	2013
Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23754383	2013
Residue-level prediction of HIV-1 antibody epitopes based on neutralization of diverse viral strains. Journal of virology\| PubMed ID: 23843642	2013
Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development. PloS one\| PubMed ID: 23861962	2013
T follicular helper cell dynamics in germinal centers. Science (New York, N.Y.)\| PubMed ID: 23887872	2013
Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies. Immunity\| PubMed ID: 23911655	2013
Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nature immunology\| PubMed ID: 23913046	2013
The origin of B cell recurrent chromosomal translocations: proximity versus DNA damage. Molecular cell\| PubMed ID: 23932709	2013
Antibodies in HIV-1 vaccine development and therapy. Science (New York, N.Y.)\| PubMed ID: 24031012	2013
Isolation of HIV-1-reactive antibodies using cell surface-expressed gp160Δc(BaL.). Journal of immunological methods\| PubMed ID: 24041474	2013
Intestinal monocytes and macrophages are required for T cell polarization in response to Citrobacter rodentium. The Journal of experimental medicine\| PubMed ID: 24043764	2013
HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24043801	2013
Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia. Nature\| PubMed ID: 24172896	2013
Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys. Nature\| PubMed ID: 24172905	2013
Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission. The Journal of experimental medicine\| PubMed ID: 24277152	2013
L-Myc expression by dendritic cells is required for optimal T-cell priming. Nature\| PubMed ID: 24509714	2014
Structural insights on the role of antibodies in HIV-1 vaccine and therapy. Cell\| PubMed ID: 24529371	2014
Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike. Cell reports\| PubMed ID: 24767986	2014
Clonal selection in the germinal centre by regulated proliferation and hypermutation. Nature\| PubMed ID: 24805232	2014
Antigen delivery to CD11c+CD8- dendritic cells induces protective immune responses against experimental melanoma in mice in vivo. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24829411	2014
Identification of chromosomal translocation hotspots via scan statistics. Bioinformatics (Oxford, England)\| PubMed ID: 24860160	2014
Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice. Cell\| PubMed ID: 25131989	2014
Classical Flt3L-dependent dendritic cells control immunity to protein vaccine. The Journal of experimental medicine\| PubMed ID: 25135299	2014
Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques. The Journal of experimental medicine\| PubMed ID: 25155019	2014
Dynamic signaling by T follicular helper cells during germinal center B cell selection. Science (New York, N.Y.)\| PubMed ID: 25170154	2014
Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity. Cell\| PubMed ID: 25215485	2014
An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex. The Journal of allergy and clinical immunology\| PubMed ID: 25312759	2015
A robust pipeline for rapid production of versatile nanobody repertoires. Nature methods\| PubMed ID: 25362362	2014
Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants. The Journal of experimental medicine\| PubMed ID: 25385756	2014
Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability. Cell\| PubMed ID: 25483776	2014
B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity. Cell\| PubMed ID: 25483777	2014
Epigenetic targeting of activation-induced cytidine deaminase. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25512519	2014
Improving neutralization potency and breadth by combining broadly reactive HIV-1 antibodies targeting major neutralization epitopes. Journal of virology\| PubMed ID: 25520506	2015
HIV-1 integration landscape during latent and active infection. Cell\| PubMed ID: 25635456	2015
Intra-spike crosslinking overcomes antibody evasion by HIV-1. Cell\| PubMed ID: 25635457	2015
Amplification of highly mutated human Ig lambda light chains from an HIV-1 infected patient. Journal of immunological methods\| PubMed ID: 25667013	2015
Circulating precursors of human CD1c+ and CD141+ dendritic cells. The Journal of experimental medicine\| PubMed ID: 25687281	2015
Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. The Journal of experimental medicine\| PubMed ID: 25687283	2015
AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges. Nature\| PubMed ID: 25707797	2015
Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117. Nature\| PubMed ID: 25855300	2015
Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas. mBio\| PubMed ID: 25900654	2015
Clonal analysis of human dendritic cell progenitor using a stromal cell culture. Journal of immunological methods\| PubMed ID: 26056939	2015
Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice. Cell\| PubMed ID: 26091035	2015
HUMORAL IMMUNITY. T cell help controls the speed of the cell cycle in germinal center B cells. Science (New York, N.Y.)\| PubMed ID: 26184917	2015
Plasmodium Infection Promotes Genomic Instability and AID-Dependent B Cell Lymphoma. Cell\| PubMed ID: 26276629	2015
Defining human dendritic cell progenitors by multiparametric flow cytometry. Nature protocols\| PubMed ID: 26292072	2015
Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching. Nature\| PubMed ID: 26308889	2015
Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nature communications\| PubMed ID: 26404402	2015
V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1. Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 26413851	2016
A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo. PLoS pathogens\| PubMed ID: 26516768	2015
Towards HIV-1 remission: potential roles for broadly neutralizing antibodies. The Journal of clinical investigation\| PubMed ID: 26752643	2016
A New Way to Diversify Antibodies by DNA Transposition. Cell\| PubMed ID: 26871626	2016
Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice. Nature communications\| PubMed ID: 26907590	2016
Independent Roles of Switching and Hypermutation in the Development and Persistence of B Lymphocyte Memory. Immunity\| PubMed ID: 26944202	2016
Structural basis for germline antibody recognition of HIV-1 immunogens. eLife\| PubMed ID: 26997349	2016
Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammation. The Journal of experimental medicine\| PubMed ID: 27001748	2016
Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection. PLoS pathogens\| PubMed ID: 27028935	2016
Inducible targeting of cDCs and their subsets in vivo. Journal of immunological methods\| PubMed ID: 27073171	2016
A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges. Nature\| PubMed ID: 27120156	2016
HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1. Science (New York, N.Y.)\| PubMed ID: 27199429	2016
Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo. Science (New York, N.Y.)\| PubMed ID: 27199430	2016
Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency. Cell\| PubMed ID: 27315478	2016
HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption. Nature\| PubMed ID: 27338952	2016
Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice. Cell\| PubMed ID: 27610569	2016
Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site. Nature structural & molecular biology\| PubMed ID: 27617431	2016
HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies. Immunity\| PubMed ID: 27617678	2016
Sequencing and cloning of antigen-specific antibodies from mouse memory B cells. Nature protocols\| PubMed ID: 27658009	2016
Human dendritic cells (DCs) are derived from distinct circulating precursors that are precommitted to become CD1c+ or CD141+ DCs. The Journal of experimental medicine\| PubMed ID: 27864467	2016
Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27872306	2016
The cell cycle restricts activation-induced cytidine deaminase activity to early G1. The Journal of experimental medicine\| PubMed ID: 27998928	2017
The Heterogeneity of Ly6C(hi) Monocytes Controls Their Differentiation into iNOS(+) Macrophages or Monocyte-Derived Dendritic Cells. Immunity\| PubMed ID: 28002729	2016
Progress toward active or passive HIV-1 vaccination. The Journal of experimental medicine\| PubMed ID: 28003309	2017
Antibody 10-1074 suppresses viremia in HIV-1-infected individuals. Nature medicine\| PubMed ID: 28092665	2017
RAG1/2 induces genomic insertions by mobilizing DNA into RAG1/2-independent breaks. The Journal of experimental medicine\| PubMed ID: 28179379	2017
Early antibody therapy can induce long-lasting immunity to SHIV. Nature\| PubMed ID: 28289286	2017
HIV: Persistence through division. The Journal of experimental medicine\| PubMed ID: 28348204	2017
Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico. Cell\| PubMed ID: 28475892	2017
Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies. eLife\| PubMed ID: 28548638	2017
Non-neutralizing Antibodies Alter the Course of HIV-1 Infection In Vivo. Cell\| PubMed ID: 28757252	2017
Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. The Journal of experimental medicine\| PubMed ID: 28847869	2017
The microanatomic segregation of selection by apoptosis in the germinal center. Science (New York, N.Y.)\| PubMed ID: 28935768	2017
Neutralizing Activity of Broadly Neutralizing Anti-HIV-1 Antibodies against Clade B Clinical Isolates Produced in Peripheral Blood Mononuclear Cells. Journal of virology\| PubMed ID: 29237833	2018
Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections. PLoS pathogens\| PubMed ID: 29505593	2018
Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope. Nature communications\| PubMed ID: 29593217	2018
Redemption for self-reactive antibodies. Science (New York, N.Y.)\| PubMed ID: 29650658	2018
Anti-HIV-1 B cell responses are dependent on B cell precursor frequency and antigen-binding affinity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 29666227	2018
Clonal CD4 T cells in the HIV-1 latent reservoir display a distinct gene profile upon reactivation. Nature medicine\| PubMed ID: 29686423	2018
Relationship between latent and rebound viruses in a clinical trial of anti-HIV-1 antibody 3BNC117. The Journal of experimental medicine\| PubMed ID: 30072495	2018
Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency. Nature immunology\| PubMed ID: 30127434	2018
Combination therapy with anti-HIV-1 antibodies maintains viral suppression. Nature\| PubMed ID: 30258136	2018
Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals. Nature medicine\| PubMed ID: 30258217	2018
The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination. Molecular cell\| PubMed ID: 30293785	2018
Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion. Cell host & microbe\| PubMed ID: 30308160	2018
A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates. Cell reports\| PubMed ID: 30403995	2018
Relationship between intact HIV-1 proviruses in circulating CD4 T cells and rebound viruses emerging during treatment interruption. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 30420517	2018
Characterization of Intact Proviruses in Blood and Lymph Node from HIV-Infected Individuals Undergoing Analytical Treatment Interruption. Journal of virology\| PubMed ID: 30700598	2019
Broadly neutralizing anti-HIV-1 monoclonal antibodies in the clinic. Nature medicine\| PubMed ID: 30936546	2019
HIV-specific humoral immune responses by CRISPR/Cas9-edited B cells. The Journal of experimental medicine\| PubMed ID: 30975893	2019
Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope. Immunity\| PubMed ID: 31126879	2019
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature\| PubMed ID: 31142836	2019
Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses. The Journal of experimental medicine\| PubMed ID: 31345931	2019
Protein Amounts of the MYC Transcription Factor Determine Germinal Center B Cell Division Capacity. Immunity\| PubMed ID: 31350178	2019
Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies. Cell reports\| PubMed ID: 34534459	2021
Combination of quadruplex qPCR and next-generation sequencing for qualitative and quantitative analysis of the HIV-1 latent reservoir. The Journal of experimental medicine\| PubMed ID: 31350309	2019
Safety, pharmacokinetics, and immunogenicity of the combination of the broadly neutralizing anti-HIV-1 antibodies 3BNC117 and 10-1074 in healthy adults: A randomized, phase 1 study. PloS one\| PubMed ID: 31393868	2019
Risk of Zika microcephaly correlates with features of maternal antibodies. The Journal of experimental medicine\| PubMed ID: 31413072	2019
Neutralizing Antibody Induction by HIV-1 Envelope Glycoprotein SOSIP Trimers on Iron Oxide Nanoparticles May Be Impaired by Mannose Binding Lectin. Journal of virology\| PubMed ID: 31852794	2020
Combination anti-HIV-1 antibody therapy is associated with increased virus-specific T cell immunity. Nature medicine\| PubMed ID: 32015556	2020
A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 32209664	2020
Antigen-responsive CD4+ T cell clones contribute to the HIV-1 latent reservoir. The Journal of experimental medicine\| PubMed ID: 32311008	2020
Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 32321830	2020
A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations. Cell host & microbe\| PubMed ID: 32504577	2020
Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals. bioRxiv : the preprint server for biology\| PubMed ID: 32511384	2020
Convergent antibody responses to SARS-CoV-2 in convalescent individuals. Nature\| PubMed ID: 32555388	2020
Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies. bioRxiv : the preprint server for biology\| PubMed ID: 32577645	2020
Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses. bioRxiv : the preprint server for biology\| PubMed ID: 32577658	2020
Durable protection against repeated penile exposures to simian-human immunodeficiency virus by broadly neutralizing antibodies. Nature communications\| PubMed ID: 32581216	2020
Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies. Cell\| PubMed ID: 32645326	2020
Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses. The Journal of experimental medicine\| PubMed ID: 32692348	2020
Characterization of Co-Formulated High-Concentration Broadly Neutralizing Anti-HIV-1 Monoclonal Antibodies for Subcutaneous Administration. Antibodies (Basel, Switzerland)\| PubMed ID: 32751063	2020
Structural classification of neutralizing antibodies against the SARS-CoV-2 spike receptor-binding domain suggests vaccine and therapeutic strategies. bioRxiv : the preprint server for biology\| PubMed ID: 32869026	2020
Recommendations for measuring HIV reservoir size in cure-directed clinical trials. Nature medicine\| PubMed ID: 32895573	2020
Enhanced SARS-CoV-2 Neutralization by Secretory IgA in vitro. bioRxiv : the preprint server for biology\| PubMed ID: 32935095	2020
An apoptosis-dependent checkpoint for autoimmunity in memory B and plasma cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 32963096	2020
Autoantibodies against type I IFNs in patients with life-threatening COVID-19. Science (New York, N.Y.)\| PubMed ID: 32972996	2020
ReScan, a Multiplex Diagnostic Pipeline, Pans Human Sera for SARS-CoV-2 Antigens. Cell reports. Medicine\| PubMed ID: 32995758	2020
Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection . bioRxiv : the preprint server for biology\| PubMed ID: 32995782	2020
SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature\| PubMed ID: 33045718	2020
A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch. eLife\| PubMed ID: 33084569	2020
Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants. eLife\| PubMed ID: 33112236	2020
Antibody Affinity Shapes the Choice between Memory and Germinal Center B Cell Fates. Cell\| PubMed ID: 33125897	2020
Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo. The Journal of experimental medicine\| PubMed ID: 33211088	2021
Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice. bioRxiv : the preprint server for biology\| PubMed ID: 33236016	2021
Enhanced SARS-CoV-2 neutralization by dimeric IgA. Science translational medicine\| PubMed ID: 33288661	2021
Neutralizing Activity of Broadly Neutralizing anti-HIV-1 Antibodies against Primary African Isolates. Journal of virology\| PubMed ID: 33298542	2020
Persistent Cellular Immunity to SARS-CoV-2 Infection. bioRxiv : the preprint server for biology\| PubMed ID: 33330867	2020
Sequence Evaluation and Comparative Analysis of Novel Assays for Intact Proviral HIV-1 DNA. Journal of virology\| PubMed ID: 33361426	2021
Single-Cell Sorting of HBsAg-Binding Memory B Cells from Human Peripheral Blood Mononuclear Cells and Antibody Cloning. STAR protocols\| PubMed ID: 33377023	2020
Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice. Science (New York, N.Y.)\| PubMed ID: 33436524	2021
Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption. Science translational medicine\| PubMed ID: 33441429	2021
Evolution of antibody immunity to SARS-CoV-2. Nature\| PubMed ID: 33461210	2021
Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice. bioRxiv : the preprint server for biology\| PubMed ID: 33532765	2021
Persistent cellular immunity to SARS-CoV-2 infection. The Journal of experimental medicine\| PubMed ID: 33533915	2021
Dynamic regulation of T selection during the germinal centre reaction. Nature\| PubMed ID: 33536617	2021
mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants. Nature\| PubMed ID: 33567448	2021
A clinical trial of non-invasive imaging with an anti-HIV antibody labelled with copper-64 in people living with HIV and uninfected controls. EBioMedicine\| PubMed ID: 33640794	2021
Mutational escape from the polyclonal antibody response to SARS-CoV-2 infection is largely shaped by a single class of antibodies. bioRxiv : the preprint server for biology\| PubMed ID: 33758856	2021
Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies. bioRxiv : the preprint server for biology\| PubMed ID: 33758864	2021
Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice. Nature\| PubMed ID: 33767445	2021
Sequencing, cloning, and antigen binding analysis of monoclonal antibodies isolated from single mouse B cells. STAR protocols\| PubMed ID: 33778783	2021
Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease. The Journal of experimental medicine\| PubMed ID: 33831141	2021
Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York. bioRxiv : the preprint server for biology\| PubMed ID: 33907745	2021
Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies. bioRxiv : the preprint server for biology\| PubMed ID: 33948592	2021
Broadly neutralizing antibody-mediated protection of macaques against repeated intravenous exposures to simian-human immunodeficiency virus. AIDS (London, England)\| PubMed ID: 33966028	2021
Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants. Nature\| PubMed ID: 34098567	2021
Germinal center-dependent and -independent memory B cells produced throughout the immune response. The Journal of experimental medicine\| PubMed ID: 34106207	2021
Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection. Nature\| PubMed ID: 34126625	2021
Early treatment with a combination of two potent neutralizing antibodies improves clinical outcomes and reduces virus replication and lung inflammation in SARS-CoV-2 infected macaques. PLoS pathogens\| PubMed ID: 34228761	2021
Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies. Nature communications\| PubMed ID: 34234131	2021
Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice. Cell reports\| PubMed ID: 34289384	2021
Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations. Immunity\| PubMed ID: 34331873	2021
Publisher Correction: Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice. Nature\| PubMed ID: 34345019	2021
Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York. Nature communications\| PubMed ID: 34373458	2021
Autoantibodies neutralizing type I IFNs are present in 4% of uninfected individuals over 70 years old and account for 20% of COVID-19 deaths. Science immunology\| PubMed ID: 34413139	2021
High genetic barrier to SARS-CoV-2 polyclonal neutralizing antibody escape. Nature\| PubMed ID: 34544114	2021
Anti-SARS-CoV-2 receptor-binding domain antibody evolution after mRNA vaccination. Nature\| PubMed ID: 34619745	2021
Integration features of intact latent HIV-1 in CD4+ T cell clones contribute to viral persistence. The Journal of experimental medicine\| PubMed ID: 34636876	2021
Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope. NPJ vaccines\| PubMed ID: 34697307	2021
Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env. Science translational medicine\| PubMed ID: 34818054	2021
Plasma neutralization properties of the SARS-CoV-2 Omicron variant. medRxiv : the preprint server for health sciences\| PubMed ID: 34931199	2021
Longitudinal clonal dynamics of HIV-1 latent reservoirs measured by combination quadruplex polymerase chain reaction and sequencing. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 35042816	2022
Germinal Centers. Annual review of immunology\| PubMed ID: 35113731	2022
Conserved Neutralizing Epitopes on the N-Terminal Domain of Variant SARS-CoV-2 Spike Proteins. bioRxiv : the preprint server for biology\| PubMed ID: 35132412	2022
Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer. Nature communications\| PubMed ID: 35136084	2022
The RIO trial: rationale, design, and the role of community involvement in a randomised placebo-controlled trial of antiretroviral therapy plus dual long-acting HIV-specific broadly neutrali... Trials\| PubMed ID: 35382844	2022
Prolonged viral suppression with anti-HIV-1 antibody therapy. Nature\| PubMed ID: 35418681	2022
Increased memory B cell potency and breadth after a SARS-CoV-2 mRNA boost. Nature\| PubMed ID: 35447027	2022
Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins. Immunity\| PubMed ID: 35447092	2022
Effect of 3BNC117 and romidepsin on the HIV-1 reservoir in people taking suppressive antiretroviral therapy (ROADMAP): a randomised, open-label, phase 2A trial. The Lancet. Microbe\| PubMed ID: 35544074	2022
Combination anti-HIV antibodies provide sustained virological suppression. Nature\| PubMed ID: 35650437	2022
Antibody evolution to SARS-CoV-2 after single-dose Ad26.COV2.S vaccine in humans. The Journal of experimental medicine\| PubMed ID: 35776090	2022
Plasma and memory antibody responses to Gamma SARS-CoV-2 provide limited cross-protection to other variants. The Journal of experimental medicine\| PubMed ID: 35796685	2022
Severe Acute Respiratory Syndrome Coronavirus 2 Neutralization After Messenger RNA Vaccination and Variant Breakthrough Infection. Open forum infectious diseases\| PubMed ID: 35818364	2022
A naturally arising broad and potent CD4-binding site antibody with low somatic mutation. Science advances\| PubMed ID: 35960796	2022
Antibody feedback regulation of memory B cell development in SARS-CoV-2 mRNA vaccination. medRxiv : the preprint server for health sciences\| PubMed ID: 35982682	2022
Humoral immunity to SARS-CoV-2 elicited by combination COVID-19 vaccination regimens. The Journal of experimental medicine\| PubMed ID: 36006380	2022
Two complementary features of humoral immune memory confer protection against the same or variant antigens. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 36006981	2022
Epistasis lowers the genetic barrier to SARS-CoV-2 neutralizing antibody escape. bioRxiv : the preprint server for biology\| PubMed ID: 36032981	2022
Antigen presentation dynamics shape the response to emergent variants like SARS-CoV-2 Omicron strain after multiple vaccinations with wild type strain. bioRxiv : the preprint server for biology\| PubMed ID: 36052368	2022
Distinct gene expression by expanded clones of quiescent memory CD4 T cells harboring intact latent HIV-1 proviruses. Cell reports\| PubMed ID: 36070690	2022
Memory B cell responses to Omicron subvariants after SARS-CoV-2 mRNA breakthrough infection in humans. The Journal of experimental medicine\| PubMed ID: 36149398	2022
HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design. Nature communications\| PubMed ID: 36253376	2022
Early intervention with 3BNC117 and romidepsin at antiretroviral treatment initiation in people with HIV-1: a phase 1b/2a, randomized trial. Nature medicine\| PubMed ID: 36253609	2022
Administration of broadly neutralizing anti-HIV-1 antibodies at ART initiation maintains long-term CD8 T cell immunity. Nature communications\| PubMed ID: 36309514	2022
HIV-1 Vpu restricts Fc-mediated effector functions in vivo. Cell reports\| PubMed ID: 36351384	2022
Antibody feedback regulates immune memory after SARS-CoV-2 mRNA vaccination. Nature\| PubMed ID: 36473496	2023
Continuous germinal center invasion contributes to the diversity of the immune response. Cell\| PubMed ID: 36565698	2023
Epistasis lowers the genetic barrier to SARS-CoV-2 neutralizing antibody escape. Nature communications\| PubMed ID: 36653360	2023