Tian-Li Wang

Department of Pathology, Johns Hopkins University School of Medicine

Affiliated withJohns Hopkins University School of Medicine Johns Hopkins University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2023

Other Publications

Article	Year
Three classes of genes mutated in colorectal cancers with chromosomal instability. Cancer research\| PubMed ID: 15126332	2004
Patterns of p53 mutations separate ovarian serous borderline tumors and low- and high-grade carcinomas and provide support for a new model of ovarian carcinogenesis: a mutational analysis wi... The American journal of surgical pathology\| PubMed ID: 15644779	2005
Activation of mitogen-activated protein kinase is required for migration and invasion of placental site trophoblastic tumor. The American journal of pathology\| PubMed ID: 16127165	2005
Amplification of a chromatin remodeling gene, Rsf-1/HBXAP, in ovarian carcinoma. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16172393	2005
Digital karyotyping: an update of its applications in cancer. Molecular diagnosis & therapy\| PubMed ID: 16884326	2006
Analysis of DNA copy number alterations in ovarian serous tumors identifies new molecular genetic changes in low-grade and high-grade carcinomas. Cancer research\| PubMed ID: 19383911	2009
Utility of p16 expression for distinction of uterine serous carcinomas from endometrial endometrioid and endocervical adenocarcinomas: immunohistochemical analysis of 201 cases. The American journal of surgical pathology\| PubMed ID: 19623034	2009
DNA copy numbers profiles in affinity-purified ovarian clear cell carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 20233889	2010
Distinct DNA methylation profiles in ovarian serous neoplasms and their implications in ovarian carcinogenesis. American journal of obstetrics and gynecology\| PubMed ID: 20965493	2010
Mutation and loss of expression of ARID1A in uterine low-grade endometrioid carcinoma. The American journal of surgical pathology\| PubMed ID: 21412130	2011
Mutation of PPP2R1A: a new clue in unveiling the pathogenesis of uterine serous carcinoma. The Journal of pathology\| PubMed ID: 21432855	2011
Molecular genetic markers in female reproductive cancers. Journal of oncology\| PubMed ID: 21541207	2010
ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers. Cancer research\| PubMed ID: 21900401	2011
Mapping DNA Quantity into Electrophoretic Mobility through Quantum Dot Nanotethers for High-Resolution Genetic and Epigenetic Analysis. ACS nano\| PubMed ID: 22136600	2012
Functional analysis of in-frame indel ARID1A mutations reveals new regulatory mechanisms of its tumor suppressor functions. Neoplasia (New York, N.Y.)\| PubMed ID: 23097632	2012
High level of chromosomal aberration in ovarian cancer genome correlates with poor clinical outcome. Gynecologic oncology\| PubMed ID: 23200914	2013
The role of forkhead box Q1 transcription factor in ovarian epithelial carcinomas. International journal of molecular sciences\| PubMed ID: 23203039	2012
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23530248	2013
Establishing isogenic inducible cell lines using founder reporter lines and recombinase-mediated cassette exchange. BioTechniques\| PubMed ID: 24215638	2013
The emerging roles of ARID1A in tumor suppression. Cancer biology & therapy\| PubMed ID: 24618703	2014
Roles of deletion of Arid1a, a tumor suppressor, in mouse ovarian tumorigenesis. Journal of the National Cancer Institute\| PubMed ID: 24899687	2014
Notch3 interactome analysis identified WWP2 as a negative regulator of Notch3 signaling in ovarian cancer. PLoS genetics\| PubMed ID: 25356737	2014
Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules. Cancer cell\| PubMed ID: 26096845	2015
Mevalonate Pathway Antagonist Suppresses Formation of Serous Tubal Intraepithelial Carcinoma and Ovarian Carcinoma in Mouse Models. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 26109099	2015
Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells. The Journal of biological chemistry\| PubMed ID: 26953344	2016
Yes-associated protein impacts adherens junction assembly through regulating actin cytoskeleton organization. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 27229120	2016
PD-L1 Expression in Human Placentas and Gestational Trophoblastic Diseases. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists\| PubMed ID: 27362903	2017
Ovarian Cancer Chemoresistance Relies on the Stem Cell Reprogramming Factor PBX1. Cancer research\| PubMed ID: 27590741	2016
Human transposon insertion profiling: Analysis, visualization and identification of somatic LINE-1 insertions in ovarian cancer. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28096347	2017
Mutation of NRAS is a rare genetic event in ovarian low-grade serous carcinoma. Human pathology\| PubMed ID: 28873354	2017
High grade serous ovarian carcinomas originate in the fallopian tube. Nature communications\| PubMed ID: 29061967	2017
Detection and localization of surgically resectable cancers with a multi-analyte blood test. Science (New York, N.Y.)\| PubMed ID: 29348365	2018
Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers. Science translational medicine\| PubMed ID: 29563323	2018
Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway. Oncogene\| PubMed ID: 29643476	2018
Methylomic Analysis of Ovarian Cancers Identifies Tumor-Specific Alterations Readily Detectable in Early Precursor Lesions. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 30108103	2018
Fallopian Tube Lesions in Women at High Risk for Ovarian Cancer: A Multicenter Study. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 30232083	2018
PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8 T-cell Function. Cancer immunology research\| PubMed ID: 30659054	2019
Molecular Classification and Emerging Targeted Therapy in Endometrial Cancer. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists\| PubMed ID: 30741844	2020
Genomic characterization of genes encoding histone acetylation modulator proteins identifies therapeutic targets for cancer treatment. Nature communications\| PubMed ID: 30760718	2019
Cytomorphologic and molecular analyses of fallopian tube fimbrial brushings for diagnosis of serous tubal intraepithelial carcinoma. Cancer cytopathology\| PubMed ID: 30861338	2019
Uncovering the Role of N-Acetyl-Aspartyl-Glutamate as a Glutamate Reservoir in Cancer. Cell reports\| PubMed ID: 30970252	2019
Loss of ARID1A in Tumor Cells Renders Selective Vulnerability to Combined Ionizing Radiation and PARP Inhibitor Therapy. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 31196855	2019
Clinicopathologic and Molecular Features of Paired Cases of Metachronous Ovarian Serous Borderline Tumor and Subsequent Serous Carcinoma. The American journal of surgical pathology\| PubMed ID: 31343420	2019
Spleen tyrosine kinase activity regulates epidermal growth factor receptor signaling pathway in ovarian cancer. EBioMedicine\| PubMed ID: 31492560	2019
-mutated ovarian serous borderline tumors are at relatively low risk for progression to serous carcinoma. Oncotarget\| PubMed ID: 31839880	2019
Epithelial Cells in Endometriosis and Adenomyosis Upregulate STING Expression. Reproductive sciences (Thousand Oaks, Calif.)\| PubMed ID: 32046461	2020
Assessing aneuploidy with repetitive element sequencing. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 32075918	2020
Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming. Nature communications\| PubMed ID: 32483112	2020
Methylomic Landscapes of Ovarian Cancer Precursor Lesions. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 32817081	2020
Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers. Cancer research\| PubMed ID: 32859605	2020
The Origin of Ovarian Cancer Species and Precancerous Landscape. The American journal of pathology\| PubMed ID: 33011111	2021
Correction: -mutated ovarian serous borderline tumors are at relatively low risk for progression to serous carcinoma. Oncotarget\| PubMed ID: 34194631	2021
A novel human endometrial epithelial cell line for modeling gynecological diseases and for drug screening. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 34376780	2021
Mutation and methylation profiles of ectopic and eutopic endometrial tissues. The Journal of pathology\| PubMed ID: 34396532	2021
Development of small molecule inhibitors targeting PBX1 transcription signaling as a novel cancer therapeutic strategy. iScience\| PubMed ID: 34816098	2021
Systems medicine dissection of chr1q-amp reveals a novel PBX1-FOXM1 axis for targeted therapy in multiple myeloma. Blood\| PubMed ID: 35015835	2022
Current and Emerging Methods for Ovarian Cancer Screening and Diagnostics: A Comprehensive Review. Cancers\| PubMed ID: 35740550	2022
Treating ARID1A mutated cancers by harnessing synthetic lethality and DNA damage response. Journal of biomedical science\| PubMed ID: 36123603	2022
Targeting glutamine metabolism enhances responses to platinum-based chemotherapy in triple-negative breast cancers (TNBC). Genes & diseases\| PubMed ID: 36157486	2022
Spatial Transcriptomic Analysis of Ovarian Cancer Precursors Reveals Reactivation of IGFBP2 during Pathogenesis. Cancer research\| PubMed ID: 36206311	2022
Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multi-cancer biomarker. bioRxiv : the preprint server for biology\| PubMed ID: 36747644	2023
A novel human endometrial epithelial cell line for modeling gynecological diseases and for drug screening. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 36775477	2021