Mitchell B. Schaffler

Department of Biomedical Engineering, The City College of New York

Affiliated withThe City College of New York

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2023

Other Publications

Article	Year
A model for the role of integrins in flow induced mechanotransduction in osteocytes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17895377	2007
Osteocyte apoptosis controls activation of intracortical resorption in response to bone fatigue. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 19049324	2009
The dependency of solute diffusion on molecular weight and shape in intact bone. Bone\| PubMed ID: 19647808	2009
Cancellous bone adaptation to tibial compression is not sex dependent in growing mice. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 20576844	2010
Tibial compression is anabolic in the adult mouse skeleton despite reduced responsiveness with aging. Bone\| PubMed ID: 21642027	2011
Activation of resorption in fatigue-loaded bone involves both apoptosis and active pro-osteoclastogenic signaling by distinct osteocyte populations. Bone\| PubMed ID: 22342796	2012
Osteocyte signaling in bone. Current osteoporosis reports\| PubMed ID: 22552701	2012
Serum IGF-1 is insufficient to restore skeletal size in the total absence of the growth hormone receptor. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 23456957	2013
Osteocytes: master orchestrators of bone. Calcified tissue international\| PubMed ID: 24042263	2014
Osteocyte apoptosis is required for production of osteoclastogenic signals following bone fatigue in vivo. Bone\| PubMed ID: 24709687	2014
Structural and mechanical repair of diffuse damage in cortical bone in vivo. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 25042459	2014
Authors response to letter from Plotkin and Bellido. Calcified tissue international\| PubMed ID: 25108470	2014
Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse post-traumatic osteoarthritis model. Arthritis research & therapy\| PubMed ID: 25516005	2014
Bone microdamage, remodeling and bone fragility: how much damage is too much damage? BoneKEy reports\| PubMed ID: 25848533	2015
Pannexin-1 and P2X7-Receptor Are Required for Apoptotic Osteocytes in Fatigued Bone to Trigger RANKL Production in Neighboring Bystander Osteocytes. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 26553756	2016
Osteocyte Apoptosis Caused by Hindlimb Unloading is Required to Trigger Osteocyte RANKL Production and Subsequent Resorption of Cortical and Trabecular Bone in Mice Femurs. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 26852281	2016
Regional differences in oxidative metabolism and mitochondrial activity among cortical bone osteocytes. Bone\| PubMed ID: 27260646	2016
Thermally induced osteocyte damage initiates pro-osteoclastogenic gene expression in vivo. Journal of the Royal Society, Interface\| PubMed ID: 27335224	2016
Lactation-Induced Changes in the Volume of Osteocyte Lacunar-Canalicular Space Alter Mechanical Properties in Cortical Bone Tissue. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 27859586	2017
Microdamage induced by in vivo Reference Point Indentation in mice is repaired by osteocyte-apoptosis mediated remodeling. Bone\| PubMed ID: 27919734	2017
Osteocyte calcium signals encode strain magnitude and loading frequency in vivo. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 29078317	2017
Potential role for a specialized β integrin-based structure on osteocyte processes in bone mechanosensation. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 29087614	2018
Correction to: Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse posttraumatic osteoarthritis model. Arthritis research & therapy\| PubMed ID: 30606217	2019
CITED2 mediates the cross-talk between mechanical loading and IL-4 to promote chondroprotection. Annals of the New York Academy of Sciences\| PubMed ID: 30891766	2019
Apoptotic Osteocytes Induce RANKL Production in Bystanders via Purinergic Signaling and Activation of Pannexin Channels. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 31910292	2020
A Bisphosphonate With a Low Hydroxyapatite Binding Affinity Prevents Bone Loss in Mice After Ovariectomy and Reverses Rapidly With Treatment Cessation. JBMR plus\| PubMed ID: 33869992	2021
Estrogen depletion on In vivo osteocyte calcium signaling responses to mechanical loading. Bone\| PubMed ID: 34171514	2021
Reply to: A Bisphosphonate With a Low Hydroxyapatite Binding Affinity Prevents Bone Loss in Mice After Ovariectomy and Reverses Rapidly With Treatment Cessation. JBMR plus\| PubMed ID: 34258501	2021