Alexander V. Zhdanov

School of Biochemistry and Cell Biology, University College Cork

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2023

Other Publications

Article	Year
Rab11-FIP3 is critical for the structural integrity of the endosomal recycling compartment. Traffic (Copenhagen, Denmark)\| PubMed ID: 17394487	2007
Dynamics of intracellular oxygen in PC12 Cells upon stimulation of neurotransmission. The Journal of biological chemistry\| PubMed ID: 18086678	2008
PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19179292	2009
In vitro analysis of cell metabolism using a long-decay pH-sensitive lanthanide probe and extracellular acidification assay. Analytical biochemistry\| PubMed ID: 19379702	2009
Intracellular oxygen-sensitive phosphorescent probes based on cell-penetrating peptides. Analytical biochemistry\| PubMed ID: 19931212	2010
Imaging of cellular oxygen and analysis of metabolic responses of mammalian cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19957136	2010
Extracellular calcium depletion transiently elevates oxygen consumption in neurosecretory PC12 cells through activation of mitochondrial Na+/Ca2+ exchange. Biochimica et biophysica acta\| PubMed ID: 20550942	2010
Monitoring of cell oxygenation and responses to metabolic stimulation by intracellular oxygen sensing technique. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 20657921	2010
Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism. Human molecular genetics\| PubMed ID: 20660115	2010
Bafilomycin A1 activates respiration of neuronal cells via uncoupling associated with flickering depolarization of mitochondria. Cellular and molecular life sciences : CMLS\| PubMed ID: 20820851	2011
Bactenecin 7 peptide fragment as a tool for intracellular delivery of a phosphorescent oxygen sensor. The FEBS journal\| PubMed ID: 20883447	2010
Intracellular O2 sensing probe based on cell-penetrating phosphorescent nanoparticles. ACS nano\| PubMed ID: 21671589	2011
Assessment of cellular oxygen gradients with a panel of phosphorescent oxygen-sensitive probes. Analytical chemistry\| PubMed ID: 22380020	2012
Bafilomycin A1 activates HIF-dependent signalling in human colon cancer cells via mitochondrial uncoupling. Bioscience reports\| PubMed ID: 22943412	2012
Chronic hypoxia leads to a glycolytic phenotype and suppressed HIF-2 signaling in PC12 cells. Biochimica et biophysica acta\| PubMed ID: 23462283	2013
Availability of the key metabolic substrates dictates the respiratory response of cancer cells to the mitochondrial uncoupling. Biochimica et biophysica acta\| PubMed ID: 23891695	2014
Imaging of neurosphere oxygenation with phosphorescent probes. Biomaterials\| PubMed ID: 24016849	2013
The mouse cyclophosphamide model of bladder pain syndrome: tissue characterization, immune profiling, and relationship to metabotropic glutamate receptors. Physiological reports\| PubMed ID: 24760514	2014
Kinetic analysis of local oxygenation and respiratory responses of mammalian cells using intracellular oxygen-sensitive probes and time-resolved fluorometry. Methods in enzymology\| PubMed ID: 24862267	2014
Imaging oxygen in neural cell and tissue models by means of anionic cell-permeable phosphorescent nanoparticles. Cellular and molecular life sciences : CMLS\| PubMed ID: 25006059	2015
Differential contribution of key metabolic substrates and cellular oxygen in HIF signalling. Experimental cell research\| PubMed ID: 25447307	2015
Cell energy budget platform for assessment of cell metabolism. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 25634285	2015
Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes. Genome biology\| PubMed ID: 25943107	2015
Prenatal stress-induced alterations in major physiological systems correlate with gut microbiota composition in adulthood. Psychoneuroendocrinology\| PubMed ID: 26135201	2015
A novel effect of DMOG on cell metabolism: direct inhibition of mitochondrial function precedes HIF target gene expression. Biochimica et biophysica acta\| PubMed ID: 26143176	2015
Imaging of oxygen gradients in giant umbrella cells: an ex vivo PLIM study. American journal of physiology. Cell physiology\| PubMed ID: 26246428	2015
Quantitative analysis of mucosal oxygenation using ex vivo imaging of healthy and inflamed mammalian colon tissue. Cellular and molecular life sciences : CMLS\| PubMed ID: 27510419	2017
Phosphorescence based O sensors - Essential tools for monitoring cell and tissue oxygenation and its impact on metabolism. Free radical biology & medicine\| PubMed ID: 27789291	2016
Cellular ROS imaging with hydro-Cy3 dye is strongly influenced by mitochondrial membrane potential. Biochimica et biophysica acta. General subjects\| PubMed ID: 27818165	2017
Low energy costs of F1Fo ATP synthase reversal in colon carcinoma cells deficient in mitochondrial complex IV. Free radical biology & medicine\| PubMed ID: 28189850	2017
Insulin-like growth factor 1 signaling is essential for mitochondrial biogenesis and mitophagy in cancer cells. The Journal of biological chemistry\| PubMed ID: 28821609	2017
AMD1 mRNA employs ribosome stalling as a mechanism for molecular memory formation. Nature\| PubMed ID: 29310120	2018
Nanoparticle-based fluoroionophore for analysis of potassium ion dynamics in 3D tissue models and . Advanced functional materials\| PubMed ID: 30271316	2018
Short-chain fatty acids and microbiota metabolites attenuate ghrelin receptor signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 31545915	2019
Small molecule phosphorescent probes for O imaging in 3D tissue models. Biomaterials science\| PubMed ID: 32481818	2014
Translation initiation downstream from annotated start codons in human mRNAs coevolves with the Kozak context. Genome research\| PubMed ID: 32669370	2020
Unusually efficient CUG initiation of an overlapping reading frame in mRNA yields novel protein POLGARF. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 32958672	2020
Reduced Oxidative Phosphorylation and Increased Glycolysis in Human Glaucoma Lamina Cribrosa Cells. Investigative ophthalmology & visual science\| PubMed ID: 33137197	2020
Mapping O concentration in ex-vivo tissue samples on a fast PLIM macro-imager. Scientific reports\| PubMed ID: 33149165	2020
The gut microbiome influences the bioavailability of olanzapine in rats. EBioMedicine\| PubMed ID: 33819741	2021
Cell Energy Budget Platform for Multiparametric Assessment of Cell and Tissue Metabolism. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 34060051	2021
Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells. FEBS open bio\| PubMed ID: 35302710	2022
Ghrelin rapidly elevates protein synthesis in vitro by employing the rpS6K-eEF2K-eEF2 signalling axis. Cellular and molecular life sciences : CMLS\| PubMed ID: 35841486	2022
Heterosubstituted Derivatives of PtPFPP for O Sensing and Cell Analysis: Structure-Activity Relationships. Bioconjugate chemistry\| PubMed ID: 36289566	2022