Lu Wang

Department of Orthopedics, Tianjin Medical University

Affiliated withTianjin Medical University Key Laboratory of State Administration of TCM (Cardio-Cerebral Vessel Collateral Disease)Shijiazhuang Compound Traditional Chinese Medicine Technology Innovation Center

Research Area

Biography

Luxi Wang is currently a Postdoctoral Research Fellow at the Wake Forest School of Medicine in North Carolina, US. She obtained her Bachelor of Medicine (MBBS) in 2012 from Fujian Medical University, Fuzhou, China. Then she moved to Belfast and received her Ph.D. in 2017 from Queen's University Belfast under the supervision of Prof. Heping Xu, with a thesis titled Metabolic control of microglial activation - the role of glucose transporter 1. She started her postdoctoral training with Dr. Asmis at Wake Forest School of Medicine since 2018.

JoVE Journal Publications

ArticleTotal : 5	Year
Publication title Cited by 1	2023
Publication title Cited by 1	2023
Publication title Cited by 1	2025
Publication title Cited by 1	2025
Publication title	2026

Other Publications

Article	Year
Interferon alpha inhibits hepatocellular carcinoma growth through inducing apoptosis and interfering with adhesion of tumor endothelial cells. Cancer letters\| PubMed ID: 19822391	2010
Ocular higher-order aberration features 10 years after photorefractive keratectomy. International ophthalmology\| PubMed ID: 23532327	2013
[Early outcomes of corneal sensitivity changes after small incision lenticule extraction and femtosecond lenticule extraction]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology\| PubMed ID: 23900087	2013
Circulating High-Molecular-Weight (HMW) Adiponectin Level Is Related with Breast Cancer Risk Better than Total Adiponectin: A Case-Control Study. PloS one\| PubMed ID: 26070203	2015
HYDROGEN-RICH MEDIUM AMELIORATES LIPOPOLYSACCHARIDE-INDUCED BARRIER DYSFUNCTION VIA RHOA-MDIA1 SIGNALING IN CACO-2 CELLS. Shock (Augusta, Ga.)\| PubMed ID: 26529665	2016
[Analysis of intraocular pressure measurement and the influencing factors after small incision lenticule extraction]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology\| PubMed ID: 26899217	2016
[Research Progress on Multiple Myeloma with Extramedullary Disease]. Zhongguo shi yan xue ye xue za zhi\| PubMed ID: 27342539	2016
[Effect of Rigorous Staging at the First Diagnosis on Prognosis of Patients with Follicular Lymphoma]. Zhongguo shi yan xue ye xue za zhi\| PubMed ID: 28245388	2017
Combined Effect of Obesity and Mobility Limitation with Incidence of Type 2 Diabetes and Mortality in Chinese Elderly. Rejuvenation research\| PubMed ID: 28398133	2017
Muscle strength rather than muscle mass is associated with osteoporosis in older Chinese adults. Journal of the Formosan Medical Association = Taiwan yi zhi\| PubMed ID: 28416075	2018
The increased risk of sarcopenia in patients with cardiovascular risk factors in Suburb-Dwelling older Chinese using the AWGS definition. Scientific reports\| PubMed ID: 28851881	2017
Hydrogen Gas Treatment Improves the Neurological Outcome After Traumatic Brain Injury Via Increasing miR-21 Expression. Shock (Augusta, Ga.)\| PubMed ID: 29028768	2018
Clinical Evidence of Exercise Benefits for Stroke. Advances in experimental medicine and biology\| PubMed ID: 29098620	2017
A Screening Tool Using Five Risk Factors Was Developed for Fall-Risk Prediction in Chinese Community-Dwelling Elderly Individuals. Rejuvenation research\| PubMed ID: 29191108	2018
Clinical characteristics and prognosis of multiple myeloma with bone-related extramedullary disease at diagnosis. Bioscience reports\| PubMed ID: 29685954	2018
Risk factors for developing diabetes after 3 years among community-dwelling elderly with impaired fasting glucose. Journal of diabetes\| PubMed ID: 29943517	2019
Inverse Relationship between Baseline Serum Albumin Levels and Risk of Mild Cognitive Impairment in Elderly: A Seven-Year Retrospective Cohort Study. The Tohoku journal of experimental medicine\| PubMed ID: 30249938	2018
Twelve-Month Incidence of Depressive Symptoms in Suburb-Dwelling Chinese Older Adults: Role of Sarcopenia. Journal of the American Medical Directors Association\| PubMed ID: 30268631	2019
Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations. Science advances\| PubMed ID: 30417093	2018
[Clinical Analysis of Maintenance Therapy with Thalidomine and Bortezomib for Multiple Myeloma]. Zhongguo shi yan xue ye xue za zhi\| PubMed ID: 30501702	2018
Clinical relevance of different handgrip strength indexes and cardiovascular disease risk factors: A cross-sectional study in suburb-dwelling elderly Chinese. Journal of the Formosan Medical Association = Taiwan yi zhi\| PubMed ID: 30522855	2019
The Relationship Between Sleep Duration, Falls, and Muscle Mass: A Cohort Study in an Elderly Chinese Population. Rejuvenation research\| PubMed ID: 30565504	2019
Phototherapy using immunologically modified carbon nanotubes to potentiate checkpoint blockade for metastatic breast cancer. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 30844573	2019
Enhanced Anti-inflammatory Activity of Peptide-Gold Nanoparticle Hybrids upon Cigarette Smoke Extract Modification through TLR Inhibition and Autophagy Induction. ACS applied materials & interfaces\| PubMed ID: 31411854	2019
Neuron-derived exosomes with high miR-21-5p expression promoted polarization of M1 microglia in culture. Brain, behavior, and immunity\| PubMed ID: 31707083	2020
Exogenous IGF-1 improves cognitive function in rats with high-fat diet consumption. Journal of molecular endocrinology\| PubMed ID: 31855559	2020
A concisely automated synthesis of TSPO radiotracer [ F]FDPA based on spirocyclic iodonium ylide method and validation for human use. Journal of labelled compounds & radiopharmaceuticals\| PubMed ID: 31895476	2020
Clinical relevance of different handgrip strength indexes and metabolic syndrome in Chinese community-dwelling elderly individuals. Archives of gerontology and geriatrics\| PubMed ID: 31951897	2020
Mild hypertension protects the elderly from cognitive impairment: a 7-year retrospective cohort study. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society\| PubMed ID: 31972899	2020
Corrigendum to "Neuron-derived exosomes with high miR-21-5p expression promoted polarization of M1 microglia in culture" [Brain Behav. Immun. 83 (2020) 270-282]. Brain, behavior, and immunity\| PubMed ID: 31980298	2020
Manipulation of macrophage polarization by peptide-coated gold nanoparticles and its protective effects on acute lung injury. Journal of nanobiotechnology\| PubMed ID: 32101146	2020
Hydrogen exerts neuroprotection by activation of the miR-21/PI3K/AKT/GSK-3β pathway in an in vitro model of traumatic brain injury. Journal of cellular and molecular medicine\| PubMed ID: 32108985	2020
Hydrogen improves cell viability partly through inhibition of autophagy and activation of PI3K/Akt/GSK3β signal pathway in a microvascular endothelial cell model of traumatic brain injury. Neurological research\| PubMed ID: 32292127	2020
Combined Depression and Malnutrition As an Effective Predictor of First Fall Onset in a Chinese Community-Dwelling Population: A 2-Year Prospective Cohort Study. Rejuvenation research\| PubMed ID: 32303149	2020
and evaluation of the safety and efficacy of a novel liquid fiducial marker for image-guided radiotherapy. Oncology letters\| PubMed ID: 32565982	2020
Exogenous IGF-1 alleviates depression-like behavior and hippocampal mitochondrial dysfunction in high-fat diet mice. Physiology & behavior\| PubMed ID: 33137345	2021
Novel Risk Loci Associated With Genetic Risk for Bipolar Disorder Among Han Chinese Individuals: A Genome-Wide Association Study and Meta-analysis. JAMA psychiatry\| PubMed ID: 33263727	2021
IGF-1 Alleviates Mitochondrial Apoptosis through the GSK3β/NF-κB/NLRP3 Signaling Pathway in LPS-Treated PC-12 Cells. Journal of molecular neuroscience : MN\| PubMed ID: 33403593	2021
Inhibition of miR-129 Improves Neuronal Pyroptosis and Cognitive Impairment Through IGF-1/GSK3β Signaling Pathway: An In Vitro and In Vivo Study. Journal of molecular neuroscience : MN\| PubMed ID: 33484421	2021
Administration route governs the therapeutic efficacy, biodistribution and macrophage targeting of anti-inflammatory nanoparticles in the lung. Journal of nanobiotechnology\| PubMed ID: 33632244	2021
Anti-Psoriatic Effects of Middle Fragment of Chlamydial Plasmid-Encoded Protein pGP3 in an Imiquimod-Induced Psoriasis Mouse Model. Medical science monitor : international medical journal of experimental and clinical research\| PubMed ID: 34088889	2021
Molecular epidemiology and genetic diversity of norovirus among hospitalized children with acute gastroenteritis in Tianjin, China, 2018-2020. BMC infectious diseases\| PubMed ID: 34261441	2021
Exogenous IGF-1 improves tau pathology and neuronal pyroptosis in high-fat diet mice with cognitive dysfunction. Metabolic brain disease\| PubMed ID: 34269982	2021
Molecular epidemiology of norovirus infections in children with acute gastroenteritis in 2017-2019 in Tianjin, China. Journal of medical virology\| PubMed ID: 34528724	2022
MiR-124 Prevents the Microglial Proinflammatory Response by Inhibiting the Activities of TLR4 and Downstream NLRP3 in Palmitic Acid-Treated BV2 Cells. Journal of molecular neuroscience : MN\| PubMed ID: 34652636	2022
The Added Value of Combined Timed Up and Go Test, Walking Speed, and Grip Strength on Predicting Recurrent Falls in Chinese Community-dwelling Elderly. Clinical interventions in aging\| PubMed ID: 34675495	2021
Clinical Course and Outcome Patterns of Acute-on-chronic Liver Failure: A Multicenter Retrospective Cohort Study. Journal of clinical and translational hepatology\| PubMed ID: 34722177	2021
Surgical Conversion for Initially Unresectable Locally Advanced Hepatocellular Carcinoma Using a Triple Combination of Angiogenesis Inhibitors, Anti-PD-1 Antibodies, and Hepatic Arterial Inf... Frontiers in oncology\| PubMed ID: 34868921	2021
Sestrin2 ablation attenuates the exercise-induced browning of white adipose tissue in C57BL/6J mice. Acta physiologica (Oxford, England)\| PubMed ID: 34995401	2022
Inhibition of Exosome Release Alleviates Cognitive Impairment After Repetitive Mild Traumatic Brain Injury. Frontiers in cellular neuroscience\| PubMed ID: 35153676	2022
A case report of intractable pyoderma gangrenosum treated with negative-pressure wound therapy. European journal of dermatology : EJD\| PubMed ID: 35171791	2022
Global Functional Connectivity Analysis Indicating Dysconnectivity of the Hate Circuit in Major Depressive Disorder. Frontiers in aging neuroscience\| PubMed ID: 35250533	2021
High-fat diet induced hippocampal CREB dysfunction, cognitive impairment and depression-like behaviors via downregulation of interleukin-2 in the mice. Metabolic brain disease\| PubMed ID: 35290547	2022
Saccharides from L. root reduce platelet activation and thrombus formation in a laser injury thrombosis mouse model. Experimental and therapeutic medicine\| PubMed ID: 35401796	2022
Chinese expert consensus on conversion therapy for hepatocellular carcinoma (2021 edition). Hepatobiliary surgery and nutrition\| PubMed ID: 35464283	2022
A novel monoacylglycerol lipase-targeted F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network. Acta pharmacologica Sinica\| PubMed ID: 35513432	2022
Mesenchymal stromal cell treatment attenuates repetitive mild traumatic brain injury-induced persistent cognitive deficits via suppressing ferroptosis. Journal of neuroinflammation\| PubMed ID: 35836233	2022
The percutaneous spinal endoscopy "isolation zone" technique for discogenic low back pain: a case series study. European journal of medical research\| PubMed ID: 36242087	2022
Single nucleotide polymorphisms of PCP pathway related genes participate in the occurrence and development of neural tube defect. Molecular genetics & genomic medicine\| PubMed ID: 36378568	2023
"Inside Disc Out" Discectomy for the Treatment of Discogenic Lumbar Spinal Canal Stenosis under the Intervertebral Foramen Endoscope. Orthopaedic surgery\| PubMed ID: 36398485	2023
PGF facilitates pathological retinal angiogenesis by modulating endothelial FOS-driven ELR CXC chemokine expression. EMBO molecular medicine\| PubMed ID: 36511116	2023
Release of STK24/25 suppression on MEKK3 signaling in endothelial cells confers Cerebral cavernous malformation. JCI insight\| PubMed ID: 36692953	2023
LDP alleviates TKI-induced proteinuria through reversing the expression of RelA in renal tissues. Frontiers in medicine\| PubMed ID: 36744132	2023
Bazi Bushen mitigates epigenetic aging and extends healthspan in naturally aging mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 36764132	2023
Functional short tandem repeat polymorphism of PTPN11 and susceptibility to hepatocellular carcinoma in Chinese populations. PloS one\| PubMed ID: 25198338	2014
From appearance to essence: 10 years review of atypical amniotic fluid embolism. Archives of gynecology and obstetrics\| PubMed ID: 26092134	2016
Loss of ARID1A expression is associated with poor prognosis in patients with gastric cancer. Human pathology\| PubMed ID: 29689245	2018
MicroRNA-504 modulates osteosarcoma cell chemoresistance to cisplatin by targeting p53. Oncology letters\| PubMed ID: 30675226	2019
Brusatol Protects HepG2 Cells against Oxygen-Glucose Deprivation-Induced Injury via Inhibiting Mitochondrial Reactive Oxygen Species-Induced Oxidative Stress. Pharmacology\| PubMed ID: 31825932	2020
Knockdown of H19 Inhibits the Pathogenesis of Acne Vulgaris by Targeting the miR-196a/TLR2/NF-κB Axis. Inflammation\| PubMed ID: 32524335	2020
MiR-1294 suppresses ROS-dependent inflammatory response in atopic dermatitis via restraining STAT3/NF-κB pathway. Cellular immunology\| PubMed ID: 34784561	2022
Importin KPNA2 confers HIV-1 pre-integration complex nuclear import by interacting with the capsid protein. Antiviral research\| PubMed ID: 35301060	2022
Differential regulation of JAK1 expression by ETS1 associated with predisposition to primary biliary cholangitis. Journal of genetics and genomics = Yi chuan xue bao\| PubMed ID: 37348755	2023
Association of different cell types and inflammation in early acne vulgaris. Frontiers in immunology\| PubMed ID: 38357543	2024
Diagnostic and grading criteria for androgenetic alopecia using dermoscopy. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)\| PubMed ID: 38533753	2024
Autocrine IL-8 Contributes to Propionibacterium Acnes-induced Proliferation and Differentiation of HaCaT Cells via AKT/FOXO1/ Autophagy. Current medical science\| PubMed ID: 39196519	2024
Analysis of the effect of levocetirizine hydrochloride dispersible tablets on inflammatory factors in the treatment of chronic urticaria. Archives of dermatological research\| PubMed ID: 40095087	2025
A machine learning model for mortality prediction in patients with severe fever with thrombocytopenia syndrome: A prospective, multicenter cohort study. Emerging microbes & infections\| PubMed ID: 40309990	2025