Philipp Dutkowski

Swiss HPB Laboratory, University Hospital Zürich

Affiliated withUniversity Hospital Zürich

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2023

Other Publications

Article	Year
Rescue of the cold preserved rat liver by hypothermic oxygenated machine perfusion. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 16611326	2006
Novel short-term hypothermic oxygenated perfusion (HOPE) system prevents injury in rat liver graft from non-heart beating donor. Annals of surgery\| PubMed ID: 17122622	2006
Abdominal drains in liver transplantation: useful tool or useless dogma? A matched case-control study. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society\| PubMed ID: 19109839	2009
One hour hypothermic oxygenated perfusion (HOPE) protects nonviable liver allografts donated after cardiac death. Annals of surgery\| PubMed ID: 19806056	2009
Current and future trends in liver transplantation in Europe. Gastroenterology\| PubMed ID: 20096694	2010
Biological modulation of liver ischemia-reperfusion injury. Current opinion in organ transplantation\| PubMed ID: 20125019	2010
Finding the right position: a three-year, single-center experience with the "self-locating" catheter. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis\| PubMed ID: 20228177	2010
Liver Transplantation because of Acute Liver Failure due to Heme Arginate Overdose in a Patient with Acute Intermittent Porphyria. Case reports in gastroenterology\| PubMed ID: 22649331	2012
Protective mechanisms of end-ischemic cold machine perfusion in DCD liver grafts. Journal of hepatology\| PubMed ID: 23063573	2013
The use of fatty liver grafts in modern allocation systems: risk assessment by the balance of risk (BAR) score. Annals of surgery\| PubMed ID: 23095632	2012
Hypothermic oxygenated perfusion (HOPE) protects from biliary injury in a rodent model of DCD liver transplantation. Journal of hepatology\| PubMed ID: 23820408	2013
Reply to letter: "The balance of risk score for allocation in liver transplantation". Annals of surgery\| PubMed ID: 23877366	2014
Successful Salvage Chemotherapy with FOLFIRINOX for Recurrent Mixed Acinar Cell Carcinoma and Ductal Adenocarcinoma of the Pancreas in an Adolescent Patient. Case reports in oncology\| PubMed ID: 24163668	2013
Novel rescue procedure for inferior vena cava reconstruction in living-donor liver transplantation using a vascular graft recovered 25 h after donors' circulatory death and systematic review... Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 24289717	2014
HOPE for human liver grafts obtained from donors after cardiac death. Journal of hepatology\| PubMed ID: 24295869	2014
Role of hypothermic machine perfusion in liver transplantation. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 24852621	2015
Warm vs. cold perfusion techniques to rescue rodent liver grafts. Journal of hepatology\| PubMed ID: 25086285	2014
Challenges to liver transplantation and strategies to improve outcomes. Gastroenterology\| PubMed ID: 25224524	2015
Hypothermic Oxygenated Perfusion (HOPE) downregulates the immune response in a rat model of liver transplantation. Annals of surgery\| PubMed ID: 25243553	2014
Reply to: "The rescue of DCD rodent livers grafts: is there HOPE?". Journal of hepatology\| PubMed ID: 25463540	2015
Conditioning With Sevoflurane in Liver Transplantation: Results of a Multicenter Randomized Controlled Trial. Transplantation\| PubMed ID: 25769076	2015
Hypothermic liver perfusion. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society\| PubMed ID: 26334767	2015
Hepatocyte Transfection in Small Pigs After Weaning by Hydrodynamic Intraportal Injection of Naked DNA/Minicircle Vectors. Human gene therapy methods\| PubMed ID: 26398117	2015
Is single portal vein approach sufficient for hypothermic machine perfusion of DCD liver grafts? Journal of hepatology\| PubMed ID: 26432684	2016
First Comparison of Hypothermic Oxygenated PErfusion Versus Static Cold Storage of Human Donation After Cardiac Death Liver Transplants: An International-matched Case Analysis. Annals of surgery\| PubMed ID: 26583664	2015
Reply to 'Is single portal vein perfusion the best approach for machine preservation of liver grafts?'. Journal of hepatology\| PubMed ID: 26845037	2016
Hypothermic machine perfusion in liver transplantation. Current opinion in organ transplantation\| PubMed ID: 26918882	2016
Liver retransplantation with cavoportal hemitransposition after percutaneous mesocaval shunt creation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society\| PubMed ID: 27096231	2016
Reply to "Reducing Nonanastomotic Biliary Strictures in Donation After Circulatory Death Liver Transplantation: Cold Ischemia Matters". Annals of surgery\| PubMed ID: 27479132	2017
Development of OXY111A, a novel hypoxia-modifier as a potential antitumor agent in patients with hepato-pancreato-biliary neoplasms - Protocol of a first Ib/IIa clinical trial. BMC cancer\| PubMed ID: 27756258	2016
Defining MoRAL After Liver Transplantation. Annals of surgery\| PubMed ID: 27759624	2017
Postoperative Delirium After Liver Transplantation is Associated With Increased Length of Stay and Lower Survival in a Prospective Cohort. Progress in transplantation (Aliso Viejo, Calif.)\| PubMed ID: 27899718	2017
Can immunosuppression be stopped after liver transplantation? The lancet. Gastroenterology & hepatology\| PubMed ID: 28606879	2017
Hypo- and normothermic perfusion of the liver: Which way to go? Best practice & research. Clinical gastroenterology\| PubMed ID: 28624105	2017
Advances in hypothermic perfusion. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society\| PubMed ID: 28815993	2017
Hypothermic oxygenated perfusion (HOPE) for fatty liver grafts in rats and humans. Journal of hepatology\| PubMed ID: 28870676	2017
Defining Benchmarks in Liver Transplantation: A Multicenter Outcome Analysis Determining Best Achievable Results. Annals of surgery\| PubMed ID: 28885508	2018
Hypothermic liver perfusion. Current opinion in organ transplantation\| PubMed ID: 28922301	2017
Potentially inappropriate liver transplantation in the era of the "sickest first" policy - A search for the upper limits. Journal of hepatology\| PubMed ID: 29133246	2018
The UK DCD Risk Score: A new proposal to define futility in donation-after-circulatory-death liver transplantation. Journal of hepatology\| PubMed ID: 29155020	2018
Uploading cellular batteries: Caring for mitochondria is key. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society\| PubMed ID: 29460371	2018
Hepatic artery occlusion in liver transplantation: What counts more, the type of reconstruction or the severity of the recipient's disease? Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society\| PubMed ID: 29493895	2018
Hypothermic Machine Preservation of the Liver: State of the Art. Current transplantation reports\| PubMed ID: 29564206	2018
Identifying risk profiles in liver transplant candidates and implications for induction immunosuppression. Transplantation reviews (Orlando, Fla.)\| PubMed ID: 29709248	2018
Perfusion settings and additives in liver normothermic machine perfusion with red blood cells as oxygen carrier. A systematic review of human and porcine perfusion protocols. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 29928775	2018
A systematic review and meta-analysis of rescue revascularization with arterial conduits in liver transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 29996000	2019
Technical Aspects of Orthotopic Liver Transplantation-a Survey-Based Study Within the Eurotransplant, Swisstransplant, Scandiatransplant, and British Transplantation Society Networks. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract\| PubMed ID: 30097968	2019
Reply to "Ex situ normothermic machine perfusion of donor livers using a haemoglobin-based oxygen carrier: a viable alternative to red blood cells". Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 30118554	2018
Outcomes of DCD liver transplantation using organs treated by hypothermic oxygenated perfusion before implantation. Journal of hepatology\| PubMed ID: 30342115	2019
Impact of Machine Perfusion on Biliary Complications after Liver Transplantation. International journal of molecular sciences\| PubMed ID: 30424553	2018
Hypothermic Oxygenated Perfusion: A Simple and Effective Method to Modulate the Immune Response in Kidney Transplantation. Transplantation\| PubMed ID: 30747849	2019
Letter to Editor: Repair or Prevent: What Is the Real Impact of Normothermic Machine Perfusion in Liver Transplantation? Hepatology (Baltimore, Md.)\| PubMed ID: 30773663	2019
Can hypothermic oxygenated perfusion (HOPE) rescue futile DCD liver grafts? HPB : the official journal of the International Hepato Pancreato Biliary Association\| PubMed ID: 30777695	2019
Normothermic regional perfusion - What is the benefit? Journal of hepatology\| PubMed ID: 31130440	2019
Correction to: Hypothermic Machine Preservation of the Liver: State of the Art. Current transplantation reports\| PubMed ID: 31329796	2018
Novel Real-time Prediction of Liver Graft Function During Hypothermic Oxygenated Machine Perfusion Before Liver Transplantation. Annals of surgery\| PubMed ID: 31592808	2019
Portobiliary Fistula in a Liver Transplant Recipient Treated With an Endoscopically Deployed Fully Covered Self-Expandable Biliary Metal Stent. ACG case reports journal\| PubMed ID: 31616750	2019
Machine perfusion strategies in liver transplantation. Hepatobiliary surgery and nutrition\| PubMed ID: 31673538	2019
An integrated perfusion machine preserves injured human livers for 1 week. Nature biotechnology\| PubMed ID: 31932726	2020
How to Handle Arterial Conduits in Liver Transplantation? Evidence From the First Multicenter Risk Analysis. Annals of surgery\| PubMed ID: 31972653	2021
Brief O uploading during continuous hypothermic machine perfusion is simple yet effective oxygenation method to improve initial kidney function in a porcine autotransplant model. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 32012434	2020
The Swiss approach to the COVID-19 outbreak. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 32330352	2020
Should kidney allografts from old donors be allocated only to old recipients? Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 32337766	2020
Modern therapeutic approaches for the treatment of malignant liver tumours. Nature reviews. Gastroenterology & hepatology\| PubMed ID: 32681074	2020
Brief Bubble and Intermittent Surface Oxygenation Is a Simple and Effective Alternative for Membrane Oxygenation During Hypothermic Machine Perfusion in Kidneys. Transplantation direct\| PubMed ID: 32766426	2020
Hypothermic, oxygenated perfusion (HOPE) provides cardioprotection via succinate oxidation prior to normothermic perfusion in a rat model of donation after circulatory death (DCD). American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 32786170	2021
Hypothermic Oxygenated Perfusion Versus Normothermic Regional Perfusion in Liver Transplantation From Controlled Donation After Circulatory Death: First International Comparative Study. Annals of surgery\| PubMed ID: 32833758	2020
Choices of Therapeutic Strategies for Colorectal Liver Metastases Among Expert Liver Surgeons: A Throw of the Dice? Annals of surgery\| PubMed ID: 32833764	2020
Hypothermic Oxygenated Liver Perfusion (HOPE) Prevents Tumor Recurrence in Liver Transplantation From Donation After Circulatory Death. Annals of surgery\| PubMed ID: 32889870	2020
Hypothermic oxygenated perfusion protects from mitochondrial injury before liver transplantation. EBioMedicine\| PubMed ID: 32979838	2020
Response to the Comment on "Injury or Function-What Is Best to Assess Organ Viability Before Liver Graft Implantation?". Annals of surgery\| PubMed ID: 33064397	2021
Reply to: Lactate measurements in an integrated perfusion machine for human livers. Nature biotechnology\| PubMed ID: 33106684	2020
Hyperoxia in portal vein causes enhanced vasoconstriction in arterial vascular bed. Scientific reports\| PubMed ID: 33262362	2020
The importance of adequate oxygenation during hypothermic machine perfusion. JHEP reports : innovation in hepatology\| PubMed ID: 33305200	2021
Bile formation in long-term ex situ perfused livers. Surgery\| PubMed ID: 33422346	2021
Viability Assessment in Liver Transplantation-What Is the Impact of Dynamic Organ Preservation? Biomedicines\| PubMed ID: 33562406	2021
Multimodal treatment strategies for colorectal liver metastases. Swiss medical weekly\| PubMed ID: 33631027	2021
Adherence to, and patient convenience of, prolonged-release tacrolimus in stable kidney and liver transplant recipients after conversion from immediate-release tacrolimus in routine clinical... Swiss medical weekly\| PubMed ID: 33638353	2021
Sources and prevention of graft infection during long-term ex situ liver perfusion. Transplant infectious disease : an official journal of the Transplantation Society\| PubMed ID: 33887094	2021
Letter to the Editor: The Concept of Real-Time Spectroscopy for Liver Viability Assessment. Hepatology (Baltimore, Md.)\| PubMed ID: 33942337	2021
Hypothermic Oxygenated Machine Perfusion Protects From Cholangiopathy in Donation after Circulatory Death Liver Transplantation. Hepatology (Baltimore, Md.)\| PubMed ID: 34233012	2021
Synthesis of coagulation factors during long-term ex situ liver perfusion. Artificial organs\| PubMed ID: 34287985	2022
Long-term Normothermic Machine Preservation of Partial Livers: First Experience With 21 Human Hemi-livers. Annals of surgery\| PubMed ID: 34334640	2021
A multicentre outcome analysis to define global benchmarks for donation after circulatory death liver transplantation. Journal of hepatology\| PubMed ID: 34655663	2022
Prolonged preservation by hypothermic machine perfusion facilitates logistics in liver transplantation: A European observational cohort study. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 35315202	2022
Liver perfusion strategies: what is best and do ischemia times still matter? Current opinion in organ transplantation\| PubMed ID: 35438271	2022
Machine perfusion in liver transplantation. Hepatology (Baltimore, Md.)\| PubMed ID: 35488496	2022
Protective mechanisms and current clinical evidence of hypothermic oxygenated machine perfusion (HOPE) in preventing post-transplant cholangiopathy. Journal of hepatology\| PubMed ID: 35589254	2022
Transplantation of a human liver following 3 days of ex situ normothermic preservation. Nature biotechnology\| PubMed ID: 35641829	2022
Corrigendum to 'Protective mechanisms and current clinical evidence of hypothermic oxygenated machine perfusion (HOPE) in preventing post-transplant cholangiopathy' [J Hepatol 76 (2022) 1330... Journal of hepatology\| PubMed ID: 35718635	2022
Low-dose aspirin confers protection against acute cellular allograft rejection after primary liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society\| PubMed ID: 35735232	2022
Impact of Machine Perfusion on the Immune Response After Liver Transplantation - A Primary Treatment or Just a Delivery Tool. Frontiers in immunology\| PubMed ID: 35874758	2022
Novel Benchmark Values for Redo Liver Transplantation: Does the Outcome Justify the Effort? Annals of surgery\| PubMed ID: 35894428	2022
Liver Transplantation as a New Standard of Care in Patients With Perihilar Cholangiocarcinoma? Results From an International Benchmark Study. Annals of surgery\| PubMed ID: 35894433	2022
Mitochondria and ischemia reperfusion injury. Current opinion in organ transplantation\| PubMed ID: 35950880	2022
Controversy Over Liver Transplantation or Resection for Neuroendocrine Liver Metastasis: Tumor Biology Cuts the Deal. Annals of surgery\| PubMed ID: 35975918	2022
Mitochondria and Cancer Recurrence after Liver Transplantation-What Is the Benefit of Machine Perfusion? International journal of molecular sciences\| PubMed ID: 36077144	2022
Machine Perfusion for Extended Criteria Donor Livers: What Challenges Remain? Journal of clinical medicine\| PubMed ID: 36079148	2022
Observations and findings during the development of a subnormothermic/normothermic long-term ex vivo liver perfusion machine. Artificial organs\| PubMed ID: 36106378	2023
A multicenter randomized-controlled trial of hypothermic oxygenated perfusion (HOPE) for human liver grafts before transplantation. Journal of hepatology\| PubMed ID: 36681160	2023
Utilization of livers donated after circulatory death for transplantation - An international comparison. Journal of hepatology\| PubMed ID: 36740047	2023
Obstacles to implement machine perfusion technology in routine clinical practice of transplantation - Why are we not there yet ? Hepatology (Baltimore, Md.)\| PubMed ID: 37013926	2023