Haichao Wang

The Feinstein Institute for Medical Research, North Shore – LIJ Health System

Affiliated withNorth Shore – LIJ Health System

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 13	2012

Other Publications

Article	Year
Globin attenuates the innate immune response to endotoxin. Shock (Augusta, Ga.)\| PubMed ID: 12069185	2002
HMGB-1, a DNA-binding protein with cytokine activity, induces brain TNF and IL-6 production, and mediates anorexia and taste aversion. Cytokine\| PubMed ID: 12126646	2002
Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature\| PubMed ID: 12508119	2003
Activation of gene expression in human neutrophils by high mobility group box 1 protein. American journal of physiology. Cell physiology\| PubMed ID: 12620891	2003
IFN-gamma induces high mobility group box 1 protein release partly through a TNF-dependent mechanism. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12646658	2003
HMGB1 as a cytokine and therapeutic target. Journal of endotoxin research\| PubMed ID: 12697092	2002
Structural basis for the proinflammatory cytokine activity of high mobility group box 1. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 12765338	2003
Further characterization of high mobility group box 1 (HMGB1) as a proinflammatory cytokine: central nervous system effects. Cytokine\| PubMed ID: 14609567	2003
Reversing established sepsis with antagonists of endogenous high-mobility group box 1. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14695889	2004
Lipid unites disparate syndromes of sepsis. Nature medicine\| PubMed ID: 14760415	2004
Extracellular HMGB1 as a proinflammatory cytokine. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research\| PubMed ID: 15212706	2004
Recombinant HMGB1 with cytokine-stimulating activity. Journal of immunological methods\| PubMed ID: 15251426	2004
Bench to bedside: HMGB1-a novel proinflammatory cytokine and potential therapeutic target for septic patients in the emergency department. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine\| PubMed ID: 15289194	2004
Pathogenic role of HMGB1 in SARS? Medical hypotheses\| PubMed ID: 15325019	2004
Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms. Journal of leukocyte biology\| PubMed ID: 15331624	2004
Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis. Nature medicine\| PubMed ID: 15502843	2004
Suppression of HMGB1 release by stearoyl lysophosphatidylcholine:an additional mechanism for its therapeutic effects in experimental sepsis. Journal of lipid research\| PubMed ID: 15687351	2005
Adrenomedullin and its binding protein attenuate the proinflammatory response after hemorrhage. Critical care medicine\| PubMed ID: 15699844	2005
The cytokine activity of HMGB1. Journal of leukocyte biology\| PubMed ID: 15734795	2005
Suppressor alphabeta T lymphocytes control innate resistance to endotoxic shock. The Journal of infectious diseases\| PubMed ID: 16107957	2005
Interferon-gamma inhibition attenuates lethality after cecal ligation and puncture in rats: implication of high mobility group box-1. Shock (Augusta, Ga.)\| PubMed ID: 16205327	2005
More tea for septic patients?--Green tea may reduce endotoxin-induced release of high mobility group box 1 and other pro-inflammatory cytokines. Medical hypotheses\| PubMed ID: 16266789	2006
The aqueous extract of a popular herbal nutrient supplement, Angelica sinensis, protects mice against lethal endotoxemia and sepsis. The Journal of nutrition\| PubMed ID: 16424112	2006
Role of HMGB1 in cardiovascular diseases. Current opinion in pharmacology\| PubMed ID: 16487750	2006
Potential role of high mobility group box 1 in viral infectious diseases. Viral immunology\| PubMed ID: 16553546	2006
Elevated high-mobility group box 1 levels in patients with cerebral and myocardial ischemia. Shock (Augusta, Ga.)\| PubMed ID: 16721263	2006
Role of HMGB1 in apoptosis-mediated sepsis lethality. The Journal of experimental medicine\| PubMed ID: 16818669	2006
HMGB1 signals through toll-like receptor (TLR) 4 and TLR2. Shock (Augusta, Ga.)\| PubMed ID: 16878026	2006
Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1. Journal of leukocyte biology\| PubMed ID: 17135572	2007
A cardiovascular drug rescues mice from lethal sepsis by selectively attenuating a late-acting proinflammatory mediator, high mobility group box 1. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17339485	2007
HMGB1 as a potential therapeutic target. Novartis Foundation symposium\| PubMed ID: 17380789	2007
Nuclear heat shock protein 72 as a negative regulator of oxidative stress (hydrogen peroxide)-induced HMGB1 cytoplasmic translocation and release. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17513788	2007
A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA. Blood\| PubMed ID: 17548579	2007
The anti-inflammatory effects of heat shock protein 72 involve inhibition of high-mobility-group box 1 release and proinflammatory function in macrophages. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17617616	2007
Adrenomedullin and adrenomedullin binding protein-1 prevent acute lung injury after gut ischemia-reperfusion. Journal of the American College of Surgeons\| PubMed ID: 17660075	2007
Transcutaneous vagus nerve stimulation reduces serum high mobility group box 1 levels and improves survival in murine sepsis. Critical care medicine\| PubMed ID: 17901837	2007
A major ingredient of green tea rescues mice from lethal sepsis partly by inhibiting HMGB1. PloS one\| PubMed ID: 17987129	2007
Alveolar macrophage suppression in sepsis is associated with high mobility group box 1 transmigration. Shock (Augusta, Ga.)\| PubMed ID: 18004227	2008
[Serum level of HMGB1 in patients with hepatitis B and its clinical significance]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology\| PubMed ID: 18073062	2007
A pilot study to detect high mobility group box 1 and heat shock protein 72 in cerebrospinal fluid of pediatric patients with meningitis. Critical care medicine\| PubMed ID: 18090368	2008
[The expression of fetuin-A and its pathological significance in fulminant hepatic failure in mice]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology\| PubMed ID: 18578995	2008
Hyperglycemia aggravates endotoxin-induced high mobility group box 1 protein release: yet another reason not to be too sweet. Critical care medicine\| PubMed ID: 18664811	2008
PACAP inhibit the release and cytokine activity of HMGB1 and improve the survival during lethal endotoxemia. International immunopharmacology\| PubMed ID: 18713653	2008
Splenectomy protects against sepsis lethality and reduces serum HMGB1 levels. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18714026	2008
Therapeutic potential of HMGB1-targeting agents in sepsis. Expert reviews in molecular medicine\| PubMed ID: 18980707	2008
Caging a Beast in the Inflammation Arena: Use of Chinese Medicinal Herbs to Inhibit a Late Mediator of Lethal Sepsis, HMGB1. International journal of clinical and experimental medicine\| PubMed ID: 19079688	2008
Ethyl pyruvate improves survival in awake hemorrhage. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 19172241	2009
Quercetin prevents LPS-induced high-mobility group box 1 release and proinflammatory function. American journal of respiratory cell and molecular biology\| PubMed ID: 19265175	2009
Novel HMGB1-inhibiting therapeutic agents for experimental sepsis. Shock (Augusta, Ga.)\| PubMed ID: 19333143	2009
Orexigenic hormone ghrelin ameliorates gut barrier dysfunction in sepsis in rats. Critical care medicine\| PubMed ID: 19531942	2009
Spermine protects mice against lethal sepsis partly by attenuating surrogate inflammatory markers. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 19593412	2009
High-mobility group box 1 protein induces tissue factor expression in vascular endothelial cells via activation of NF-kappaB and Egr-1. Thrombosis and haemostasis\| PubMed ID: 19652887	2009
Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor-factor VIII [corrected]. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19812188	2009
High mobility group box 1 protein as a potential drug target for infection- and injury-elicited inflammation. Inflammation & allergy drug targets\| PubMed ID: 19906009	2010
Peripheral administration of fetuin-A attenuates early cerebral ischemic injury in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 19953099	2010
[Effect of HMGB1 on human hepatoma cell line-HepG2 proliferation]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences\| PubMed ID: 20543468	2010
A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20547845	2010
A hepatic protein, fetuin-A, occupies a protective role in lethal systemic inflammation. PloS one\| PubMed ID: 21347455	2011
EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages. Biochemical pharmacology\| PubMed ID: 21371444	2011
HMGB1 cytoplasmic translocation in patients with acute liver failure. BMC gastroenterology\| PubMed ID: 21406085	2011
Peripheral administration of human adrenomedullin and its binding protein attenuates stroke-induced apoptosis and brain injury in rats. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 21695352	2011
Recombinant human MFG-E8 attenuates cerebral ischemic injury: its role in anti-inflammation and anti-apoptosis. Neuropharmacology\| PubMed ID: 21964436	2012
Anti-Inflammatory Role of Fetuin-A in Injury and Infection. Current molecular medicine\| PubMed ID: 22292896	2012
Inhibition of HMGB1 Enhances Bacterial Clearance and Protects against P. aeruginosa Pneumonia in Cystic Fibrosis. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 22314397	2012
Exposure of perfluorononanoic acid suppresses the hepatic insulin signal pathway and increases serum glucose in rats. Toxicology\| PubMed ID: 22387981	2012