Anthony E. Pickering

Anaesthesia, University of Bristol

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2023

Other Publications

Article	Year
Activation of Brainstem Pro-opiomelanocortin Neurons Produces Opioidergic Analgesia, Bradycardia and Bradypnoea. PloS one\| PubMed ID: 27077912	2016
The nucleus of the solitary tract: an integrating station for nociceptive and cardiorespiratory afferents. Experimental physiology\| PubMed ID: 11856972	2002
Investigation of systemic bupivacaine toxicity using the in situ perfused working heart-brainstem preparation of the rat. Anesthesiology\| PubMed ID: 12459684	2002
Nociception attenuates parasympathetic but not sympathetic baroreflex via NK1 receptors in the rat nucleus tractus solitarii. The Journal of physiology\| PubMed ID: 12813142	2003
Targeting brain stem centers of cardiovascular control using adenoviral vectors: impact of promoters on transgene expression. Physiological genomics\| PubMed ID: 15561757	2005
A decerebrate, artificially-perfused in situ preparation of rat: utility for the study of autonomic and nociceptive processing. Journal of neuroscience methods\| PubMed ID: 16499970	2006
Disinhibition of the cardiac limb of the arterial baroreflex in rat: a role for metabotropic glutamate receptors in the nucleus tractus solitarii. The Journal of physiology\| PubMed ID: 16809369	2006
Hierarchical recruitment of the sympathetic and parasympathetic limbs of the baroreflex in normotensive and spontaneously hypertensive rats. The Journal of physiology\| PubMed ID: 17170043	2007
Reflexly evoked coactivation of cardiac vagal and sympathetic motor outflows: observations and functional implications. Clinical and experimental pharmacology & physiology\| PubMed ID: 17184509	2006
Dominant role of aortic baroreceptors in the cardiac baroreflex of the rat in situ. Autonomic neuroscience : basic & clinical\| PubMed ID: 18479978	2008
Retrograde adenoviral vector targeting of nociresponsive pontospinal noradrenergic neurons in the rat in vivo. The Journal of comparative neurology\| PubMed ID: 19003793	2009
Retrograde viral vector-mediated inhibition of pontospinal noradrenergic neurons causes hyperalgesia in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19828800	2009
Analgesia in conjunction with normalisation of thermal sensation following deep brain stimulation for central post-stroke pain. Pain\| PubMed ID: 19833434	2009
TRPA1-expressing primary afferents synapse with a morphologically identified subclass of substantia gelatinosa neurons in the adult rat spinal cord. The European journal of neuroscience\| PubMed ID: 20497466	2010
An exploration of the control of micturition using a novel in situ arterially perfused rat preparation. Frontiers in neuroscience\| PubMed ID: 21625609	2011
Processing of central and reflex vagal drives by rat cardiac ganglion neurones: an intracellular analysis. The Journal of physiology\| PubMed ID: 22005679	2011
Prolonged ketamine infusion as a therapy for complex regional pain syndrome: synergism with antagonism? British journal of clinical pharmacology\| PubMed ID: 23701138	2014
A functional analysis of the influence of β3-adrenoceptors on the rat micturition cycle. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 24008334	2013
Systemic dexmedetomidine augments inhibitory synaptic transmission in the superficial dorsal horn through activation of descending noradrenergic control: an in vivo patch-clamp analysis of a... Pain\| PubMed ID: 24355412	2014
Optoactivation of locus ceruleus neurons evokes bidirectional changes in thermal nociception in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24647936	2014
Mapping the cellular electrophysiology of rat sympathetic preganglionic neurones to their roles in cardiorespiratory reflex integration: a whole cell recording study in situ. The Journal of physiology\| PubMed ID: 24665100	2014
Increased intrinsic excitability of muscle vasoconstrictor preganglionic neurons may contribute to the elevated sympathetic activity in hypertensive rats. Journal of neurophysiology\| PubMed ID: 25122704	2014
Intrathecal reboxetine suppresses evoked and ongoing neuropathic pain behaviours by restoring spinal noradrenergic inhibitory tone. Pain\| PubMed ID: 25599454	2015
Modelling the vascular response to sympathetic postganglionic nerve activity. Journal of theoretical biology\| PubMed ID: 25698230	2015
Influence of age on respiratory modulation of muscle sympathetic nerve activity, blood pressure and baroreflex function in humans. Experimental physiology\| PubMed ID: 26154775	2015
Retrograde optogenetic characterization of the pontospinal module of the locus coeruleus with a canine adenoviral vector. Brain research\| PubMed ID: 26903420	2016
Characterising the Analgesic Effect of Different Targets for Deep Brain Stimulation in Trigeminal Anaesthesia Dolorosa. Stereotactic and functional neurosurgery\| PubMed ID: 27322524	2016
Deep brain stimulation of the periaqueductal gray releases endogenous opioids in humans. NeuroImage\| PubMed ID: 27554530	2017
Brainstem sources of cardiac vagal tone and respiratory sinus arrhythmia. The Journal of physiology\| PubMed ID: 27654879	2016
Resolving the Brainstem Contributions to Attentional Analgesia. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 28096471	2017
Single Electrode Deep Brain Stimulation with Dual Targeting at Dual Frequency for the Treatment of Chronic Pain: A Case Series and Review of the Literature. Brain sciences\| PubMed ID: 28098766	2017
Muro-Neuro-Urodynamics; a Review of the Functional Assessment of Mouse Lower Urinary Tract Function. Frontiers in physiology\| PubMed ID: 28220079	2017
Functional dichotomy in spinal- vs prefrontal-projecting locus coeruleus modules splits descending noradrenergic analgesia from ascending aversion and anxiety in rats. eLife\| PubMed ID: 29027903	2017
Characterization of mouse neuro-urological dynamics in a novel decerebrate arterially perfused mouse (DAPM) preparation. Neurourology and urodynamics\| PubMed ID: 29333621	2018
Ultrasound-guided, open-source microneurography: Approaches to improve recordings from peripheral nerves in man. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology\| PubMed ID: 30107982	2018
Abnormal Locus Coeruleus Sleep Activity Alters Sleep Signatures of Memory Consolidation and Impairs Place Cell Stability and Spatial Memory. Current biology : CB\| PubMed ID: 30393040	2018
Locus Coeruleus tracking of prediction errors optimises cognitive flexibility: An Active Inference model. PLoS computational biology\| PubMed ID: 30608922	2019
Sildenafil, a phosphodiesterase type 5 inhibitor, augments sphincter bursting and bladder afferent activity to enhance storage function and voiding efficiency in mice. BJU international\| PubMed ID: 30636087	2019
Modulation of Bladder Wall Micromotions Alters Intravesical Pressure Activity in the Isolated Bladder. Frontiers in physiology\| PubMed ID: 30687132	2018
Platelet dysfunction after Out of Hospital Cardiac Arrest. Results from POHCAR: A prospective observational, cohort study. Resuscitation\| PubMed ID: 30716426	2019
Behavioral correlates of activity of optogenetically identified locus coeruleus noradrenergic neurons in rats performing T-maze tasks. Scientific reports\| PubMed ID: 30718532	2019
Assessing Long-term Neurodevelopmental Outcome Following General Anesthesia in Early Childhood: Challenges and Opportunities. Anesthesia and analgesia\| PubMed ID: 30883414	2019
Influence of sildenafil on the purinergic components of nerve-mediated and urothelial ATP release from the bladder of normal and spinal cord injured mice. British journal of pharmacology\| PubMed ID: 30924527	2019
Hedonic drinking engages a supraspinal inhibition of thermal nociception in adult rats. Pain\| PubMed ID: 31008815	2019
On the presence and functional significance of sympathetic premotor neurons with collateralized spinal axons in the rat. The Journal of physiology\| PubMed ID: 31077360	2019
Acceptability of a primary care-based opioid and pain review service: a mixed-methods evaluation in England. The British journal of general practice : the journal of the Royal College of General Practitioners\| PubMed ID: 31594772	2020
Redefining Noradrenergic Neuromodulation of Behavior: Impacts of a Modular Locus Coeruleus Architecture. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 31619493	2019
Evaluation of a primary care-based opioid and pain review service: a mixed-methods evaluation in two GP practices in England. The British journal of general practice : the journal of the Royal College of General Practitioners\| PubMed ID: 31791939	2020
Regulation of food intake by astrocytes in the brainstem dorsal vagal complex. Glia\| PubMed ID: 31880353	2020
Interventions to treat pain in paediatric CFS/ME: a systematic review. BMJ paediatrics open\| PubMed ID: 32201745	2020
Locus coeruleus norepinephrine activity mediates sensory-evoked awakenings from sleep. Science advances\| PubMed ID: 32285002	2020
Probabilistic, spinally-gated control of bladder pressure and autonomous micturition by Barrington's nucleus CRH neurons. eLife\| PubMed ID: 32347794	2020
Noradrenaline Release from Locus Coeruleus Terminals in the Hippocampus Enhances Excitation-Spike Coupling in CA1 Pyramidal Neurons Via β-Adrenoceptors. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 32607551	2020
Sweet taste does not modulate pain perception in adult humans. Wellcome open research\| PubMed ID: 32704547	2020
Parallel cortical-brainstem pathways to attentional analgesia. NeuroImage\| PubMed ID: 33186712	2021
The effects of xenon on sevoflurane anesthesia-induced acidosis and brain cell apoptosis in immature rats. Paediatric anaesthesia\| PubMed ID: 33187024	2021
Anatomically and functionally distinct locus coeruleus efferents mediate opposing effects on anxiety-like behavior. Neurobiology of stress\| PubMed ID: 33344735	2020
The safety of anaesthetists and intensivists during the first COVID-19 surge supports extension of use of airborne protection PPE to ward staff. Clinical medicine (London, England)\| PubMed ID: 33509933	2021
Loss of cortical control over the descending pain modulatory system determines the development of the neuropathic pain state in rats. eLife\| PubMed ID: 33555256	2021
Central pain modulatory mechanisms of attentional analgesia are preserved in fibromyalgia. Pain\| PubMed ID: 33941755	2022
Identification of the source events for aerosol generation during oesophago-gastro-duodenoscopy. Gut\| PubMed ID: 34187844	2022
Multisite silicon probes enable simultaneous recording of spontaneous and evoked activity in multiple isolated C-fibres in rat saphenous nerve. Journal of neuroscience methods\| PubMed ID: 34800543	2022
Evaluating the association of TRPA1 gene polymorphisms with pain sensitivity: a protocol for an adaptive recall by genotype study. BMC medical genomics\| PubMed ID: 35022050	2022
Simultaneous brain, brainstem, and spinal cord pharmacological-fMRI reveals involvement of an endogenous opioid network in attentional analgesia. eLife\| PubMed ID: 35080494	2022
Advancing respiratory-cardiovascular physiology with the working heart-brainstem preparation over 25 years. The Journal of physiology\| PubMed ID: 35294064	2022
Pro-opiomelanocortin neurons in the nucleus of the solitary tract mediate endorphinergic endogenous analgesia in mice. Pain\| PubMed ID: 36448978	2023