Ole Munk

Department of Nuclear Medicine & PET-Center, Aarhus University Hospital

Affiliated withAarhus University Hospital

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2023

Other Publications

Article	Year
Metabolic fate of 18F-FDG in mice bearing either SCCVII squamous cell carcinoma or C3H mammary carcinoma. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 12097467	2002
Impulse-response function of splanchnic circulation with model-independent constraints: theory and experimental validation. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 12686507	2003
Capillaries within compartments: microvascular interpretation of dynamic positron emission tomography data. Journal of theoretical biology\| PubMed ID: 14559065	2003
Determination of regional flow by use of intravascular PET tracers: microvascular theory and experimental validation for pig livers. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 14602871	2003
11C-methionine PET, a novel method for measuring regional salivary gland function after radiotherapy of head and neck cancer. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology\| PubMed ID: 15588873	2004
Hepatic microcirculation assessed by positron emission tomography of first-pass ammonia metabolism in porcine liver. Liver international : official journal of the International Association for the Study of the Liver\| PubMed ID: 15698415	2005
Effect of intratumoral heterogeneity in oxygenation status on FMISO PET, autoradiography, and electrode Po2 measurements in murine tumors. International journal of radiation oncology, biology, physics\| PubMed ID: 15936570	2005
Brain metabolism of 13N-ammonia during acute hepatic encephalopathy in cirrhosis measured by positron emission tomography. Hepatology (Baltimore, Md.)\| PubMed ID: 16374868	2006
Individual radiation response of parotid glands investigated by dynamic 11C-methionine PET. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology\| PubMed ID: 16545879	2006
Peripheral benzodiazepine receptors in the brain of cirrhosis patients with manifest hepatic encephalopathy. European journal of nuclear medicine and molecular imaging\| PubMed ID: 16550382	2006
Hepatic uptake and metabolism of galactose can be quantified in vivo by 2-[18F]fluoro-2-deoxygalactose positron emission tomography. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 18483186	2008
A method to estimate dispersion in sampling catheters and to calculate dispersion-free blood time-activity curves. Medical physics\| PubMed ID: 18777907	2008
ISSLS prize winner: positron emission tomography and magnetic resonance imaging for monitoring interbody fusion with equine bone protein extract, recombinant human bone morphogenetic protein... Spine\| PubMed ID: 19002076	2008
Benefits and risks of transforming data from dynamic positron emission tomography, with an application to hepatic encephalopathy. Journal of theoretical biology\| PubMed ID: 19038272	2009
Backflux of ammonia from brain to blood in human subjects with and without hepatic encephalopathy. Metabolic brain disease\| PubMed ID: 19067140	2009
Hepatic ethanol elimination kinetics in patients with cirrhosis. Scandinavian journal of gastroenterology\| PubMed ID: 19404864	2009
Human (13)N-ammonia PET studies: the importance of measuring (13)N-ammonia metabolites in blood. Metabolic brain disease\| PubMed ID: 20217201	2010
Assessing hypoxia in animal tumor models based on pharmocokinetic analysis of dynamic FAZA PET. Acta oncologica (Stockholm, Sweden)\| PubMed ID: 20831479	2010
Identifying hypoxia in human tumors: A correlation study between 18F-FMISO PET and the Eppendorf oxygen-sensitive electrode. Acta oncologica (Stockholm, Sweden)\| PubMed ID: 20831480	2010
Tracer input for kinetic modelling of liver physiology determined without sampling portal venous blood in pigs. European journal of nuclear medicine and molecular imaging\| PubMed ID: 20882283	2011
Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 21636533	2011
Hepatic blood perfusion measured by 3-minute dynamic 18F-FDG PET in pigs. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 21680685	2011
Analogue tracers and lumped constant in capillary beds. Journal of theoretical biology\| PubMed ID: 21756919	2011
Model-independent plot of dynamic PET data facilitates data interpretation and model selection. Journal of theoretical biology\| PubMed ID: 22094364	2012
PET kinetics of radiolabeled antidepressant, [N-methyl-11C]mirtazapine, in the human brain. EJNMMI research\| PubMed ID: 22214419	2011
[N-methyl-11C]cholylsarcosine, a novel bile acid tracer for PET/CT of hepatic excretory function: radiosynthesis and proof-of-concept studies in pigs. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 22454486	2012
Hepatic blood perfusion estimated by dynamic contrast-enhanced computed tomography in pigs: limitations of the slope method. Investigative radiology\| PubMed ID: 22836307	2012
Hepatic encephalopathy is associated with decreased cerebral oxygen metabolism and blood flow, not increased ammonia uptake. Hepatology (Baltimore, Md.)\| PubMed ID: 22886493	2013
In vivo imaging of human acetylcholinesterase density in peripheral organs using 11C-donepezil: dosimetry, biodistribution, and kinetic analyses. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 25324520	2014
Imaging acetylcholinesterase density in peripheral organs in Parkinson's disease with 11C-donepezil PET. Brain : a journal of neurology\| PubMed ID: 25539902	2015
Metabolic liver function measured in vivo by dynamic (18)F-FDGal PET/CT without arterial blood sampling. EJNMMI research\| PubMed ID: 26034654	2015
Radiosynthesis of N-¹¹C-Methyl-Taurine-Conjugated Bile Acids and Biodistribution Studies in Pigs by PET/CT. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 26697965	2016
A PET Tracer for Renal Organic Cation Transporters, ¹¹C-Metformin: Radiosynthesis and Preclinical Proof-of-Concept Studies. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 26769859	2016
Hepatobiliary Secretion Kinetics of Conjugated Bile Acids Measured in Pigs by 11C-Cholylsarcosine PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 26966160	2016
[11C]-Labeled Metformin Distribution in the Liver and Small Intestine Using Dynamic Positron Emission Tomography in Mice Demonstrates Tissue-Specific Transporter Dependency. Diabetes\| PubMed ID: 26993065	2016
Renal PET-imaging with (11)C-metformin in a transgenic mouse model for chronic kidney disease. EJNMMI research\| PubMed ID: 27339044	2016
2-[(18)F]fluoro-2-deoxy-D-galactose PET/CT of hepatocellular carcinoma is not improved by co-administration of galactose. Nuclear medicine and biology\| PubMed ID: 27434609	2016
In Vivo Imaging of Human 11C-Metformin in Peripheral Organs: Dosimetry, Biodistribution, and Kinetic Analyses. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 27469359	2016
Point-spread function reconstructed PET images of sub-centimeter lesions are not quantitative. EJNMMI physics\| PubMed ID: 28091957	2017
FDG-PET reproducibility in tumor-bearing mice: comparing a traditional SUV approach with a tumor-to-brain tissue ratio approach. Acta oncologica (Stockholm, Sweden)\| PubMed ID: 28094665	2017
Hepatobiliary transport kinetics of the conjugated bile acid tracer C-CSar quantified in healthy humans and patients by positron emission tomography. Journal of hepatology\| PubMed ID: 28249726	2017
Magnetic resonance imaging and computed tomography as tools for the investigation of sperm whale (Physeter macrocephalus) teeth and eye. Acta veterinaria Scandinavica\| PubMed ID: 28606113	2017
Muscle Tissue Saturation Compared With Muscle Tissue Perfusion During Low Blood Flows: An Experimental Study. Journal of cardiothoracic and vascular anesthesia\| PubMed ID: 28693932	2017
The potential of hyperpolarized C magnetic resonance spectroscopy to monitor the effect of combretastatin based vascular disrupting agents. Acta oncologica (Stockholm, Sweden)\| PubMed ID: 28840759	2017
Hypoxia positron emission tomography imaging: combining information on perfusion and tracer retention to improve hypoxia specificity. Acta oncologica (Stockholm, Sweden)\| PubMed ID: 28840765	2017
Metabolic liver function in humans measured by 2-F-fluoro-2-deoxy-D-galactose PET/CT-reproducibility and clinical potential. EJNMMI research\| PubMed ID: 28853060	2017
Hepatic metabolism of C-methionine and secretion of C-protein measured by PET in pigs. American journal of nuclear medicine and molecular imaging\| PubMed ID: 28913155	2017
A microvascular compartment model validated using C-methylglucose liver PET in pigs. Physics in medicine and biology\| PubMed ID: 29045236	2017
Whole-Body Biodistribution, Dosimetry, and Metabolite Correction of [C]Palmitate: A PET Tracer for Imaging of Fatty Acid Metabolism. Molecular imaging\| PubMed ID: 29073808	2017
Cerebral blood flow measured by positron emission tomography during normothermic cardiopulmonary bypass: an experimental porcine study. Perfusion\| PubMed ID: 29380669	2018
Metformin does not affect postabsorptive hepatic free fatty acid uptake, oxidation or resecretion in humans: A 3-month placebo-controlled clinical trial in patients with type 2 diabetes and ... Diabetes, obesity & metabolism\| PubMed ID: 29405635	2018
Monitoring variables affecting positron emission tomography measurements of cerebral blood flow in anaesthetized pigs. Acta veterinaria Scandinavica\| PubMed ID: 29530059	2018
Quantitative PET of liver functions. American journal of nuclear medicine and molecular imaging\| PubMed ID: 29755841	2018
Prognostic modeling for patients with colorectal liver metastases incorporating FDG PET radiomic features. European journal of radiology\| PubMed ID: 30927933	2019
Hepatic exposure of metformin in patients with non-alcoholic fatty liver disease. British journal of clinical pharmacology\| PubMed ID: 30973968	2019
Human biodistribution, dosimetry, radiosynthesis and quality control of the bile acid PET tracer [N-methyl-C]cholylsarcosine. Nuclear medicine and biology\| PubMed ID: 31330413	2019
Metformin is distributed to tumor tissue in breast cancer patients in vivo: A C-metformin PET/CT study. Breast cancer research and treatment\| PubMed ID: 32240455	2020
Activation of NMDA receptor ion channels by deep brain stimulation in the pig visualised with [F]GE-179 PET. Brain stimulation\| PubMed ID: 32388196	2020
Intravenous and oral copper kinetics, biodistribution and dosimetry in healthy humans studied by [Cu]copper PET/CT. EJNMMI radiopharmacy and chemistry\| PubMed ID: 32556736	2020
Obeticholic acid improves hepatic bile acid excretion in patients with primary biliary cholangitis. Journal of hepatology\| PubMed ID: 32717289	2021
Brain-first versus body-first Parkinson's disease: a multimodal imaging case-control study. Brain : a journal of neurology\| PubMed ID: 32830221	2020
Successful Prediction of Positron Emission Tomography-Imaged Metformin Hepatic Uptake Clearance in Humans Using the Quantitative Proteomics-Informed Relative Expression Factor Approach. Drug metabolism and disposition: the biological fate of chemicals\| PubMed ID: 32843330	2020
Clinical feasibility and impact of fully automated multiparametric PET imaging using direct Patlak reconstruction: evaluation of 103 dynamic whole-body F-FDG PET/CT scans. European journal of nuclear medicine and molecular imaging\| PubMed ID: 32894338	2021
NMDA receptor ion channel activation detected in vivo with [F]GE-179 PET after electrical stimulation of rat hippocampus. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 32960687	2021
Correction to: Clinical feasibility and impact of fully automated multiparametric PET imaging using direct Patlak reconstruction: evaluation of 103 dynamic whole-body 18F-FDG PET/CT scans. European journal of nuclear medicine and molecular imaging\| PubMed ID: 33582877	2021
Hepatic bile acid transport increases in the postprandial state: A functional C-CSar PET/CT study in healthy humans. JHEP reports : innovation in hepatology\| PubMed ID: 34095797	2021
Validation and optimisation of an automatic blood sampler for preclinical positron emission tomography research in domestic pigs. Laboratory animals\| PubMed ID: 34596450	2022
Reply to: "Hepatic bile acid transport increases in the postprandial state: A functional C-CSar PET/CT study in healthy humans". JHEP reports : innovation in hepatology\| PubMed ID: 34746727	2021
The pathophysiology of Wilson's disease visualized: A human Cu PET study. Hepatology (Baltimore, Md.)\| PubMed ID: 34773664	2022
Normal values for F-FDG uptake in organs and tissues measured by dynamic whole body multiparametric FDG PET in 126 patients. EJNMMI research\| PubMed ID: 35254514	2022
Clinical feasibility and impact of data-driven respiratory motion compensation studied in 200 whole-body F-FDG PET/CT scans. EJNMMI research\| PubMed ID: 35347465	2022
In vivo vesicular acetylcholine transporter density in human peripheral organs: an [F]FEOBV PET/CT study. EJNMMI research\| PubMed ID: 35362761	2022
Clinical validation of a population-based input function for 20-min dynamic whole-body F-FDG multiparametric PET imaging. EJNMMI physics\| PubMed ID: 36076097	2022
N-(4-[F]fluorobenzyl)cholylglycine, a potential tracer for positron emission tomography of enterohepatic circulation and drug-induced inhibition of ileal bile acid transport. A proof-of-conc... Nuclear medicine and biology\| PubMed ID: 36095922	2022
[F]FEOBV positron emission tomography may not be a suitable method to measure parasympathetic denervation in patients with Parkinson's disease. Parkinsonism & related disorders\| PubMed ID: 36198248	2022
Mapping Cholinergic Synaptic Loss in Parkinson's Disease: An [18F]FEOBV PET Case-Control Study. Journal of Parkinson's disease\| PubMed ID: 36336941	2022
Distribution of cholinergic nerve terminals in the aged human brain measured with [F]FEOBV PET and its correlation with histological data. NeuroImage\| PubMed ID: 36720436	2023
Multiparametric dynamic whole-body PSMA PET/CT using [Ga]Ga-PSMA-11 and [F]PSMA-1007. EJNMMI research\| PubMed ID: 37060394	2023