Marcela Brissova

Division of Diabetes, Vanderbilt University Medical Center

Affiliated withVanderbilt University Medical Center

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2023

Other Publications

Article	Year
Assessment of insulin secretion in the mouse. Methods in molecular medicine\| PubMed ID: 12619713	2003
A fall in portal vein insulin does not cause the alpha-cell response to mild, non-insulin-induced hypoglycemia in conscious dogs. Metabolism: clinical and experimental\| PubMed ID: 14624400	2003
Intraislet endothelial cells contribute to revascularization of transplanted pancreatic islets. Diabetes\| PubMed ID: 15111502	2004
H-Ras, R-Ras, and TC21 differentially regulate ureteric bud cell branching morphogenesis. Molecular biology of the cell\| PubMed ID: 16467383	2006
Polymer scaffolds as synthetic microenvironments for extrahepatic islet transplantation. Transplantation\| PubMed ID: 16926587	2006
Molecular imaging of vascular endothelial growth factor receptor 2 expression using targeted contrast-enhanced high-frequency ultrasonography. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine\| PubMed ID: 17957052	2007
Enhanced expression of VEGF-A in β cells increases endothelial cell number but impairs islet morphogenesis and β cell proliferation. Developmental biology\| PubMed ID: 22546694	2012
Pancreatic islet vasculature adapts to insulin resistance through dilation and not angiogenesis. Diabetes\| PubMed ID: 23630302	2013
Vascular endothelial growth factor-a and islet vascularization are necessary in developing, but not adult, pancreatic islets. Diabetes\| PubMed ID: 23884891	2013
Islet microenvironment, modulated by vascular endothelial growth factor-A signaling, promotes β cell regeneration. Cell metabolism\| PubMed ID: 24561261	2014
Pancreas development in humans. Current opinion in endocrinology, diabetes, and obesity\| PubMed ID: 24569548	2014
Automated quantification of pancreatic β-cell mass. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 24760991	2014
Human islet preparations distributed for research exhibit a variety of insulin-secretory profiles. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 25648831	2015
Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet β-Cell Function. The Journal of biological chemistry\| PubMed ID: 25851902	2015
Human Islets Have Fewer Blood Vessels than Mouse Islets and the Density of Islet Vascular Structures Is Increased in Type 2 Diabetes. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 26216139	2015
Microtubules Negatively Regulate Insulin Secretion in Pancreatic β Cells. Developmental cell\| PubMed ID: 26418295	2015
Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing β-cells to a δ-like fate and reveals a facultative proliferative capacity in aged β-cells. Development (Cambridge, England)\| PubMed ID: 26534984	2015
Development of a reliable automated screening system to identify small molecules and biologics that promote human β-cell regeneration. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 27624103	2016
Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nature medicine\| PubMed ID: 27798614	2016
Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors. Nature communications\| PubMed ID: 28835709	2017
Mouse pancreatic islet macrophages use locally released ATP to monitor beta cell activity. Diabetologia\| PubMed ID: 28884198	2018
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes. Cell reports\| PubMed ID: 29514095	2018
Cystic fibrosis-related diabetes is caused by islet loss and inflammation. JCI insight\| PubMed ID: 29669939	2018
β-Cell DNA Damage Response Promotes Islet Inflammation in Type 1 Diabetes. Diabetes\| PubMed ID: 30150306	2018
Examining How the MAFB Transcription Factor Affects Islet β-Cell Function Postnatally. Diabetes\| PubMed ID: 30425060	2019
Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis. Cell metabolism\| PubMed ID: 30449685	2019
Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks. The Journal of clinical investigation\| PubMed ID: 30507613	2019
HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes. Diabetes\| PubMed ID: 30833470	2019
Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue. Diabetologia\| PubMed ID: 30955045	2019
The Integrated Islet Distribution Program answers the call for improved human islet phenotyping and reporting of human islet characteristics in research articles. Diabetologia\| PubMed ID: 31089753	2019
The Integrated Islet Distribution Program Answers the Call for Improved Human Islet Phenotyping and Reporting of Human Islet Characteristics in Research Articles. Diabetes\| PubMed ID: 31092479	2019
Modeling Monogenic Diabetes using Human ESCs Reveals Developmental and Metabolic Deficiencies Caused by Mutations in HNF1A. Cell stem cell\| PubMed ID: 31374199	2019
Integrated human pseudoislet system and microfluidic platform demonstrate differences in GPCR signaling in islet cells. JCI insight\| PubMed ID: 32352931	2020
Decreased pancreatic acinar cell number in type 1 diabetes. Diabetologia\| PubMed ID: 32388592	2020
SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells. Cell metabolism\| PubMed ID: 33207245	2020
Pancreatlas: Applying an Adaptable Framework to Map the Human Pancreas in Health and Disease. Patterns (New York, N.Y.)\| PubMed ID: 33294866	2020
Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors. Translational psychiatry\| PubMed ID: 33589583	2021
Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration. NPJ Regenerative medicine\| PubMed ID: 33824346	2021
The Human Islet: Mini-Organ With Mega-Impact. Endocrine reviews\| PubMed ID: 33844836	2021
Combinatorial transcription factor profiles predict mature and functional human islet α and β cells. JCI insight\| PubMed ID: 34428183	2021
Microvessels enhance vascularization and function of transplanted insulin-producing cells. Cell metabolism\| PubMed ID: 34731653	2021
Integrated Analysis of the Pancreas and Islets Reveals Unexpected Findings in Human Male With Type 1 Diabetes. Journal of the Endocrine Society\| PubMed ID: 34870058	2021
Images From the Exeter Archival Diabetes Biobank Now Accessible via Pancreatlas. Diabetes care\| PubMed ID: 36239401	2022
Human pancreatic capillaries and nerve fibers persist in type 1 diabetes despite beta cell loss. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 36696598	2023
The human α cell in health and disease. The Journal of endocrinology\| PubMed ID: 37114672	2023
Exocrine pancreas in type 1 and type 2 diabetes: different patterns of fibrosis, metaplasia, angiopathy, and adiposity. Diabetes\| PubMed ID: 37881846	2023