synthesis-of-decellularized-cartilage-extracellular-matrix-hydrogels

Synthesis of Decellularized Cartilage Extracellular Matrix Hydrogels

Decellularized cartilage extracellular matrix (DC-ECM) hydrogels are promising biomaterials for tissue engineering and regenerative medicine due to their ...

Tongde Hospital Of Zhejiang Province

Gout can cause redness, swelling, local heat, severe pain, and limitation of function of the affected joints and surrounding tissues. Gouty tophi are commonly found in the auricle, joints, Achilles tendon and tarsal bursa. However, gouty tophi rarely affect the talus.

Autologous osteochondral graft as treatment for gouty tophus in the talus: A case report.

In humans, the trachea is a conduit for ventilation connecting the throat and lungs. However, certain congenital or acquired diseases may cause long-term tracheal defects that require replacement. Tissue engineering is considered a promising method to reconstruct long-segment tracheal lesions and restore the structure and function of the trachea. Decellularization technology retains the natural structure of the trachea, has good biocompatibility and mechanical properties, and is currently a hotspot in tissue engineering studies. This article lists various recent representative protocols for the generation of decellularized tracheal scaffolds (DTSs), as well as their validity and limitations. Based on the advancements in decellularization methods, we discussed the impact and importance of mechanical properties, revascularization, recellularization, and biocompatibility in the production and implantation of DTS. This review provides a basis for future research on DTS and its application in clinical therapy.

Article	Year
Autologous osteochondral graft as treatment for gouty tophus in the talus: A case report. Medicine\| PubMed ID: 33592814	2021
Decellularized tracheal scaffolds in tracheal reconstruction: An evaluation of different techniques. Journal of applied biomaterials & functional materials\| PubMed ID: 34903089	2021

Sheng Mei

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