Roman J. Szczesny

Institute of Biochemistry and Biophysics, Polish Academy of Sciences

Affiliated withPolish Academy of Sciences Polish Academy of Sciences

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2023

Other Publications

Article	Year
Down-regulation of human RNA/DNA helicase SUV3 induces apoptosis by a caspase- and AIF-dependent pathway. Biology of the cell\| PubMed ID: 17352692	2007
Human mitochondrial RNA turnover caught in flagranti: involvement of hSuv3p helicase in RNA surveillance. Nucleic acids research\| PubMed ID: 19864255	2010
The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L. The EMBO journal\| PubMed ID: 20531386	2010
[Final doctorate competition 2009. Study of hSuv3p human helicase function]. Postepy biochemii\| PubMed ID: 21473039	2010
Human Suv3 protein reveals unique features among SF2 helicases. Acta crystallographica. Section D, Biological crystallography\| PubMed ID: 22101826	2011
RNA degradation in yeast and human mitochondria. Biochimica et biophysica acta\| PubMed ID: 22178375	2012
Human mitochondrial RNA decay mediated by PNPase-hSuv3 complex takes place in distinct foci. Nucleic acids research\| PubMed ID: 23221631	2013
Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels. Nucleic acids research\| PubMed ID: 23358826	2013
A new strategy for gene targeting and functional proteomics using the DT40 cell line. Nucleic acids research\| PubMed ID: 23892402	2013
Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target. Nucleic acids research\| PubMed ID: 24150935	2014
Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease. Human molecular genetics\| PubMed ID: 24986917	2014
Two novel C-terminal frameshift mutations in the β-globin gene lead to rapid mRNA decay. BMC medical genetics\| PubMed ID: 28595636	2017
Versatile approach for functional analysis of human proteins and efficient stable cell line generation using FLP-mediated recombination system. PloS one\| PubMed ID: 29590189	2018
Dedicated surveillance mechanism controls G-quadruplex forming non-coding RNAs in human mitochondria. Nature communications\| PubMed ID: 29967381	2018
Mitochondrial double-stranded RNA triggers antiviral signalling in humans. Nature\| PubMed ID: 30046113	2018
Controlling the mitochondrial antisense - role of the SUV3-PNPase complex and its co-factor GRSF1 in mitochondrial RNA surveillance. Molecular & cellular oncology\| PubMed ID: 30525095	2018
Quantitative proteomics revealed C6orf203/MTRES1 as a factor preventing stress-induced transcription deficiency in human mitochondria. Nucleic acids research\| PubMed ID: 31226201	2019
Mitochondrial Gene Expression and Beyond-Novel Aspects of Cellular Physiology. Cells\| PubMed ID: 31861673	2019
Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA. Nucleic acids research\| PubMed ID: 32365187	2020
Loading messenger RNAs onto ribosomes in human mitochondria: lessons learned from a bacterial toxin. The FEBS journal\| PubMed ID: 32588551	2021
High-Throughput Measurement of Mitochondrial RNA Turnover in Human Cultured Cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 33230771	2021
DNA Repair Protein APE1 Degrades Dysfunctional Abasic mRNA in Mitochondria Affecting Oxidative Phosphorylation. Journal of molecular biology\| PubMed ID: 34224750	2021
Human Mitochondrial RNA Processing and Modifications: Overview. International journal of molecular sciences\| PubMed ID: 34360765	2021
Mitochondrial RNA, a new trigger of the innate immune system. Wiley interdisciplinary reviews. RNA\| PubMed ID: 34498404	2022
Landscape of functional interactions of human processive ribonucleases revealed by high-throughput siRNA screenings. iScience\| PubMed ID: 34541468	2021
In vitro reconstitution reveals a key role of human mitochondrial EXOG in RNA primer processing. Nucleic acids research\| PubMed ID: 35819194	2022