tuina-intervention-in-rabbit-model-of-knee-osteoarthritis

Tuina Intervention in Rabbit Model of Knee Osteoarthritis

Knee osteoarthritis (KOA) is mainly characterized by degenerative changes in the knee joint's cartilage and surrounding soft tissues. The efficacy of ...

warm-moxibustion-scraping-as-traditional-chinese-medicine-therapy-for

Warm Moxibustion and Scraping as a Traditional Chinese Medicine Therapy for Cervical Spondylosis Treatment

Cervical spondylosis (CS) is characterized by abnormal sensations such as pain in the occiput, neck, and shoulder, which may be accompanied by pressure ...

Liaoning University of Traditional Chinese Medicine

Rheumatoid arthritis (RA) is an inflammatory immune-mediated disease that involves synovitis, cartilage destruction, and even joint damage. Traditional agents used for RA therapy remain unsatisfactory because of their low efficiency and obvious adverse effects. Therefore, we here established RA microenvironment-responsive targeted micelles that can respond to the increase in reactive oxygen species (ROS) levels in the joint and improve macrophage-specific targeting of loaded drugs.

Combined ROS Sensitive Folate Receptor Targeted Micellar Formulations of Curcumin Effective Against Rheumatoid Arthritis in Rat Model.

To explore the therapeutic effects of Zhuyang Tongbian Decoction (ZTD) on vasoactive intestinal peptide (VIP) and 5-hydroxytryptamine receptor (5-HTR) in colon tissues, intestinal flora, and fecal metabolites in mice with functional constipation (FC).

Use of 16s RNA and metabolomics to investigate the therapeutic effect of Zhuyang Tongbian Decoction on mice with functional constipation.

To explore the mechanism of Zhuyang Tongbian Decoction (ZTD) in treating functional constipation (FC) by observing its effects on intestinal flora composition, the metabolic function of gut microbiota, fecal short-chain fatty acid (SCFA) levels, and serum concentrations of TLR4, NF-κB, TNF-α, and IL-6 in patients with FC.

Therapeutic Mechanism of Zhuyang Tongbian Decoction in Treating Functional Constipation: Insights from a Pilot Study Utilizing 16S rRNA Sequencing, Metagenomics, and Metabolomics.

Observational studies have shown a link between constipation (CN) and psychiatric disorders, including Schizophrenia (SP), Bipolar disorder (BD), Schizoaffective disorder (SD), and Parkinson's disease (PD). However, it is still unknown whether CN affects the occurrence and development of psychiatric disorders or whether psychiatric disorders cause the occurrence and development of CN. Therefore, this study used Mendelian randomization (MR) analysis to evaluate the relationship between CN and psychiatric disorders.

ArticleTotal : 2	Year
Publication title Cited by 3	2023
Publication title	2025

Article	Year
Combined ROS Sensitive Folate Receptor Targeted Micellar Formulations of Curcumin Effective Against Rheumatoid Arthritis in Rat Model. International journal of nanomedicine\| PubMed ID: 38766660	2024
Use of 16s RNA and metabolomics to investigate the therapeutic effect of Zhuyang Tongbian Decoction on mice with functional constipation. American journal of translational research\| PubMed ID: 39959240	2025
Therapeutic Mechanism of Zhuyang Tongbian Decoction in Treating Functional Constipation: Insights from a Pilot Study Utilizing 16S rRNA Sequencing, Metagenomics, and Metabolomics. International journal of general medicine\| PubMed ID: 40026814	2025
Constipation and Psychiatric Disorders: A Bidirectional Mendelian Randomization Study. Combinatorial chemistry & high throughput screening\| PubMed ID: 40375699	2025

Xuan Zhang

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