Sergii Afonin

Karlsruhe Institute of Technology

Affiliated withKarlsruhe Institute of Technology

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 7	2023

Other Publications

Article	Year
Synthesis of trifluoromethyl-substituted proline analogues as 19F NMR labels for peptides in the polyproline II conformation. Angewandte Chemie (International ed. in English)\| PubMed ID: 18576439	2008
Conformation and membrane orientation of amphiphilic helical peptides by oriented circular dichroism. Biophysical journal\| PubMed ID: 18621832	2008
Temperature-dependent transmembrane insertion of the amphiphilic peptide PGLa in lipid bilayers observed by solid state 19F NMR spectroscopy. Journal of the American Chemical Society\| PubMed ID: 19049452	2008
Using a sterically restrictive amino acid as a 19F NMR label to monitor and to control peptide aggregation in membranes. Journal of the American Chemical Society\| PubMed ID: 19554688	2008
Chemical labeling strategy with (R)- and (S)-trifluoromethylalanine for solid state 19F NMR analysis of peptaibols in membranes. Journal of the American Chemical Society\| PubMed ID: 19827760	2009
Dynamic transitions of membrane-active peptides. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20094866	2010
19F NMR analysis of the antimicrobial peptide PGLa bound to native cell membranes from bacterial protoplasts and human erythrocytes. Journal of the American Chemical Society\| PubMed ID: 20550126	2010
Structural role of the conserved cysteines in the dimerization of the viral transmembrane oncoprotein E5. Biophysical journal\| PubMed ID: 20858420	2010
Special issue on membrane-active peptides. European biophysics journal : EBJ\| PubMed ID: 21286705	2011
Solid-state (19)F-NMR of peptides in native membranes. Topics in current chemistry\| PubMed ID: 21598096	2012
Alignment of druglike compounds in lipid bilayers analyzed by solid-state (19)F-NMR and molecular dynamics, based on dipolar couplings of adjacent CF3 groups. The journal of physical chemistry. B\| PubMed ID: 22439912	2012
Hydrophobic matching controls the tilt and stability of the dimeric platelet-derived growth factor receptor (PDGFR) β transmembrane segment. The Journal of biological chemistry\| PubMed ID: 22619173	2012
Antimicrobial Peptides can Enhance the Risk of Persistent Infections. Frontiers in immunology\| PubMed ID: 22870073	2012
Structure analysis of the membrane-bound PhoD signal peptide of the Tat translocase shows an N-terminal amphiphilic helix. Biochimica et biophysica acta\| PubMed ID: 22960285	2012
Incorporation of cis- and trans-4,5-difluoromethanoprolines into polypeptides. Organic letters\| PubMed ID: 23020292	2012
Solid State NMR Structure Analysis of the Antimicrobial Peptide Gramicidin S in Lipid Membranes: Concentration-Dependent Re-alignment and Self-Assembly as a β-Barrel. Topics in current chemistry\| PubMed ID: 23605461	2008
Stereochemical effects on the aggregation and biological properties of the fibril-forming peptide [KIGAKI]3 in membranes. Physical chemistry chemical physics : PCCP\| PubMed ID: 23652359	2013
Controlling biological activity with light: diarylethene-containing cyclic peptidomimetics. Angewandte Chemie (International ed. in English)\| PubMed ID: 24554486	2014
(19)F NMR screening of unrelated antimicrobial peptides shows that membrane interactions are largely governed by lipids. Biochimica et biophysica acta\| PubMed ID: 24699372	2014
Structure analysis and conformational transitions of the cell penetrating peptide transportan 10 in the membrane-bound state. PloS one\| PubMed ID: 24937132	2014
Control and role of pH in peptide-lipid interactions in oriented membrane samples. Biochimica et biophysica acta\| PubMed ID: 25511586	2015
Action of the multifunctional peptide BP100 on native biomembranes examined by solid-state NMR. Journal of biomolecular NMR\| PubMed ID: 25616492	2015
γ-(S)-Trifluoromethyl proline: evaluation as a structural substitute of proline for solid state (19)F-NMR peptide studies. Organic & biomolecular chemistry\| PubMed ID: 25703116	2015
Fermentation and Cost-Effective 13C/15N Labeling of the Nonribosomal Peptide Gramicidin S for Nuclear Magnetic Resonance Structure Analysis. Applied and environmental microbiology\| PubMed ID: 25795666	2015
Direct Photocontrol of Peptidomimetics: An Alternative to Oxygen-Dependent Photodynamic Cancer Therapy. Angewandte Chemie (International ed. in English)\| PubMed ID: 27028784	2016
Does a methionine-to-norleucine substitution in PGLa influence peptide-membrane interactions? Biochimica et biophysica acta\| PubMed ID: 27267703	2016
Membrane Thinning and Thickening Induced by Membrane-Active Amphipathic Peptides. Frontiers in cell and developmental biology\| PubMed ID: 27595096	2016
Therapeutic Potential of Gramicidin S in the Treatment of Root Canal Infections. Pharmaceuticals (Basel, Switzerland)\| PubMed ID: 27618065	2016
Design, Synthesis, and Application of an Optimized Monofluorinated Aliphatic Label for Peptide Studies by Solid-State F NMR Spectroscopy. Angewandte Chemie (International ed. in English)\| PubMed ID: 27706889	2016
Delivering Structural Information on the Polar Face of Membrane-Active Peptides: F-NMR Labels with a Cationic Side Chain. Angewandte Chemie (International ed. in English)\| PubMed ID: 27761988	2016
Coding and decoding libraries of sequence-defined functional copolymers synthesized via photoligation. Nature communications\| PubMed ID: 27901024	2016
Orientation and Location of the Cyclotide Kalata B1 in Lipid Bilayers Revealed by Solid-State NMR. Biophysical journal\| PubMed ID: 28256223	2017
Antimicrobial peptide gramicidin S is accumulated in granules of producer cells for storage of bacterial phosphagens. Scientific reports\| PubMed ID: 28295017	2017
Diphytanoyl lipids as model systems for studying membrane-active peptides. Biochimica et biophysica acta. Biomembranes\| PubMed ID: 28587828	2017
Loosening of Lipid Packing Promotes Oligoarginine Entry into Cells. Angewandte Chemie (International ed. in English)\| PubMed ID: 28597524	2017
Conformational Plasticity of the Cell-Penetrating Peptide SAP As Revealed by Solid-State F-NMR and Circular Dichroism Spectroscopies. The journal of physical chemistry. B\| PubMed ID: 28608690	2017
Structural Behavior of the Peptaibol Harzianin HK VI in a DMPC Bilayer: Insights from MD Simulations. Biophysical journal\| PubMed ID: 28636916	2017
Lactam-Stapled Cell-Penetrating Peptides: Cell Uptake and Membrane Binding Properties. Journal of medicinal chemistry\| PubMed ID: 28921993	2017
Flexibility vs rigidity of amphipathic peptide conjugates when interacting with lipid bilayers. Biochimica et biophysica acta. Biomembranes\| PubMed ID: 28958778	2017
Orthogonal F-Labeling for Solid-State NMR Spectroscopy Reveals the Conformation and Orientation of Short Peptaibols in Membranes. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 29323432	2018
Efficiently Photocontrollable or Not? Biological Activity of Photoisomerizable Diarylethenes. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 29633378	2018
Structure-Activity Relationships of Photoswitchable Diarylethene-Based β-Hairpin Peptides as Membranolytic Antimicrobial and Anticancer Agents. Journal of medicinal chemistry\| PubMed ID: 30452249	2018
Inhibition of Pseudomonas aeruginosa biofilm formation and expression of virulence genes by selective epimerization in the peptide Esculentin-1a(1-21)NH. The FEBS journal\| PubMed ID: 31144441	2019
Supreme activity of gramicidin S against resistant, persistent and biofilm cells of staphylococci and enterococci. Scientific reports\| PubMed ID: 31784584	2019
Light-controllable dithienylethene-modified cyclic peptides: photoswitching the in vivo toxicity in zebrafish embryos. Beilstein journal of organic chemistry\| PubMed ID: 31976015	2020
Nanomolar Synthesis in Droplet Microarrays with UV-Triggered On-Chip Cell Screening. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 31985878	2020
Enhancing the activity of membrane remodeling epsin-peptide by trimerization. Bioorganic & medicinal chemistry letters\| PubMed ID: 32317210	2020
Diarylethene moiety as an enthalpy-entropy switch: photoisomerizable stapled peptides for modulating p53/MDM2 interaction. Organic & biomolecular chemistry\| PubMed ID: 32390036	2020
Structural and functional characterization of the pore-forming domain of pinholin S68. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 33154156	2020
TAT-RasGAP kills cells by targeting inner-leaflet-enriched phospholipids. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 33257567	2020
Behavior of the Antibacterial Peptide Cyclo[RRRWFW], Explored Using a 3-Hydroxychromone-Derived Fluorescent Amino Acid. Frontiers in chemistry\| PubMed ID: 34262894	2021
Diarylethene-Based Photoswitchable Inhibitors of Serine Proteases. Angewandte Chemie (International ed. in English)\| PubMed ID: 34268844	2021
Probing and Manipulating the Lateral Pressure Profile in Lipid Bilayers Using Membrane-Active Peptides-A Solid-State F NMR Study. International journal of molecular sciences\| PubMed ID: 35562938	2022
Towards in vivo photomediated delivery of anticancer peptides: Insights from pharmacokinetic and -dynamic data. Journal of photochemistry and photobiology. B, Biology\| PubMed ID: 35660309	2022
Highly Fluorinated Peptide Probes with Enhanced In Vivo Stability for F-MRI. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 36074982	2022
Length matters: Functional flip of the short TatA transmembrane helix. Biophysical journal\| PubMed ID: 36523158	2023
Structural Dissection of Epsin-1 N-Terminal Helical Peptide: The Role of Hydrophobic Residues in Modulating Membrane Curvature. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 36878866	2023