Alan L. Schwartz

Department of Pediatrics, Washington University School of Medicine

Affiliated withWashington University School of Medicine

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2023

Other Publications

Article	Year
The ubiquitin-proteasome pathway: the complexity and myriad functions of proteins death. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 9501156	1998
Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 9653139	1998
Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain. Molecular and cellular biology\| PubMed ID: 10207090	1999
SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase. The EMBO journal\| PubMed ID: 10835356	2000
Receptor-associated protein facilitates proper folding and maturation of the low-density lipoprotein receptor and its class 2 mutants. Biochemistry\| PubMed ID: 11939787	2002
Low density lipoprotein (LDL) receptor-related protein 1B impairs urokinase receptor regeneration on the cell surface and inhibits cell migration. The Journal of biological chemistry\| PubMed ID: 12194987	2002
Proteasome regulates the delivery of LDL receptor-related protein into the degradation pathway. Molecular biology of the cell\| PubMed ID: 12221136	2002
Determinants of nuclear and cytoplasmic ubiquitin-mediated degradation of MyoD. The Journal of biological chemistry\| PubMed ID: 12397066	2003
Cellular catabolism of lipid poor apolipoprotein E via cell surface LDL receptor-related protein. Journal of biochemistry\| PubMed ID: 12417024	2002
Degradation of the LDL receptor class 2 mutants is mediated by a proteasome-dependent pathway. Journal of lipid research\| PubMed ID: 14993243	2004
Ubiquitin-Proteasome-mediated degradation of Id1 is modulated by MyoD. The Journal of biological chemistry\| PubMed ID: 15163661	2004
LRP6 expression promotes cancer cell proliferation and tumorigenesis by altering beta-catenin subcellular distribution. Oncogene\| PubMed ID: 15516984	2004
Independent and cooperative roles of N-glycans and molecular chaperones in the folding and disulfide bond formation of the low-density lipoprotein (LDL) receptor-related protein. Biochemistry\| PubMed ID: 15823038	2005
Ubiquitin-proteasome-mediated degradation, intracellular localization, and protein synthesis of MyoD and Id1 during muscle differentiation. The Journal of biological chemistry\| PubMed ID: 15888449	2005
E12 and E47 modulate cellular localization and proteasome-mediated degradation of MyoD and Id1. Oncogene\| PubMed ID: 16007194	2005
Slow endocytosis of the LDL receptor-related protein 1B: implications for a novel cytoplasmic tail conformation. Experimental cell research\| PubMed ID: 17658514	2007
In vivo interactions of MyoD, Id1, and E2A proteins determined by acceptor photobleaching fluorescence resonance energy transfer. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 18198216	2008
Glucocorticoids differentially regulate degradation of MyoD and Id1 by N-terminal ubiquitination to promote muscle protein catabolism. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18296633	2008
Targeting proteins for destruction by the ubiquitin system: implications for human pathobiology. Annual review of pharmacology and toxicology\| PubMed ID: 18834306	2009
Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9. Cancer research\| PubMed ID: 19176371	2009
Ubiquitin proteasome-dependent degradation of the transcriptional coactivator PGC-1{alpha} via the N-terminal pathway. The Journal of biological chemistry\| PubMed ID: 20713359	2010
The Future of Children's Health in the Genomic Era. Rambam Maimonides medical journal\| PubMed ID: 23908811	2011
American Pediatric Society 2014 presidential address: the thrill of discovery (and other foundations of biomedical research). Pediatric research\| PubMed ID: 24937547	2014
Isoform-specific SCF(Fbw7) ubiquitination mediates differential regulation of PGC-1α. Journal of cellular physiology\| PubMed ID: 25204433	2015
RNF4-Dependent Oncogene Activation by Protein Stabilization. Cell reports\| PubMed ID: 27653698	2016
Physician-Scientist Career Awards and a Dilemma: National Institute of Child Health and Human Development K Awards-Individual, Institutional, or National? JAMA pediatrics\| PubMed ID: 29340560	2018
RNA-Seq identifies genes whose proteins are transformative in the differentiation of cytotrophoblast to syncytiotrophoblast, in human primary villous and BeWo trophoblasts. Scientific reports\| PubMed ID: 29572450	2018
Noninvasive high-resolution electromyometrial imaging of uterine contractions in a translational sheep model. Science translational medicine\| PubMed ID: 30867320	2019
Accuracy of electromyometrial imaging of uterine contractions in clinical environment. Computers in biology and medicine\| PubMed ID: 31786490	2020
Electromyometrial imaging dataset of electromyograms and isochrone maps under deformation/electrical noise contaminations. Data in brief\| PubMed ID: 31956675	2020
Addressing Gaps in Pediatric Scientist Development: The Department Chair View of 2 AMSPDC-Sponsored Programs. The Journal of pediatrics\| PubMed ID: 32586535	2020
RNA-Seq identifies genes whose proteins are upregulated during syncytia development in murine C2C12 myoblasts and human BeWo trophoblasts. Physiological reports\| PubMed ID: 33403800	2021
Analysis of Electrophysiological Activation of the Uterus During Human Labor Contractions. JAMA network open\| PubMed ID: 35653158	2022
Noninvasive electromyometrial imaging of human uterine maturation during term labor. Nature communications\| PubMed ID: 36918533	2023