E. Scott Graham

Department of Molecular Medicine and Pathology, University of Auckland

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2023

Other Publications

Article	Year
Induction of Krox-24 by endogenous cannabinoid type 1 receptors in Neuro2A cells is mediated by the MEK-ERK MAPK pathway and is suppressed by the phosphatidylinositol 3-kinase pathway. The Journal of biological chemistry\| PubMed ID: 16864584	2006
Specific detection of CB1 receptors; cannabinoid CB1 receptor antibodies are not all created equal! Journal of neuroscience methods\| PubMed ID: 18406468	2008
Cannabinoid Receptors: A brief history and what not. Frontiers in bioscience (Landmark edition)\| PubMed ID: 19273110	2009
Detailed characterisation of CB2 receptor protein expression in peripheral blood immune cells from healthy human volunteers using flow cytometry. International journal of immunopathology and pharmacology\| PubMed ID: 20377992	2010
Cannabinoid Receptor 1 trafficking and the role of the intracellular pool: implications for therapeutics. Biochemical pharmacology\| PubMed ID: 20599795	2010
Real-time profiling of NK cell killing of human astrocytes using xCELLigence technology. Journal of neuroscience methods\| PubMed ID: 21781988	2011
Detailed analysis of inflammatory and neuromodulatory cytokine secretion from human NT2 astrocytes using multiplex bead array. Neurochemistry international\| PubMed ID: 21939706	2012
Sensitive and accurate quantification of human leukocyte migration using high-content Discovery-1 imaging system and ATPlite assay. Journal of biomolecular screening\| PubMed ID: 22140120	2012
M1 muscarinic receptor activation mediates cell death in M1-HEK293 cells. PloS one\| PubMed ID: 24023725	2013
Adult human glia, pericytes and meningeal fibroblasts respond similarly to IFNy but not to TGFβ1 or M-CSF. PloS one\| PubMed ID: 24339874	2013
A Cell Derived Active Contour (CDAC) method for robust tracking in low frame rate, low contrast phase microscopy - an example: the human hNT astrocyte. PloS one\| PubMed ID: 24358233	2013
Exposure to inflammatory cytokines IL-1β and TNFα induces compromise and death of astrocytes; implications for chronic neuroinflammation. PloS one\| PubMed ID: 24367648	2013
Enrichment of differentiated hNT neurons and subsequent analysis using flow-cytometry and xCELLigence sensing. Journal of neuroscience methods\| PubMed ID: 24530700	2014
Development of positive control tissue for in situ hybridisation using Alvetex scaffolds. Journal of neuroscience methods\| PubMed ID: 25244955	2014
Application of xCELLigence RTCA Biosensor Technology for Revealing the Profile and Window of Drug Responsiveness in Real Time. Biosensors\| PubMed ID: 25893878	2015
Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells. Journal of neuroinflammation\| PubMed ID: 26152369	2015
Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors. Scientific reports\| PubMed ID: 26813587	2016
TGF-beta1 regulates human brain pericyte inflammatory processes involved in neurovasculature function. Journal of neuroinflammation\| PubMed ID: 26867675	2016
Cultured pericytes from human brain show phenotypic and functional differences associated with differential CD90 expression. Scientific reports\| PubMed ID: 27215737	2016
Plasmin and regulators of plasmin activity control the migratory capacity and adhesion of human T cells and dendritic cells by regulating cleavage of the chemokine CCL21. Immunology and cell biology\| PubMed ID: 27301418	2016
Statins Inhibit Fibrillary β-Amyloid Induced Inflammation in a Model of the Human Blood Brain Barrier. PloS one\| PubMed ID: 27309956	2016
Interferon-γ blocks signalling through PDGFRβ in human brain pericytes. Journal of neuroinflammation\| PubMed ID: 27654972	2016
ECIS technology reveals that monocytes isolated by CD14+ve selection mediate greater loss of BBB integrity than untouched monocytes, which occurs to a greater extent with IL-1β activated end... PloS one\| PubMed ID: 28732059	2017
Is the Cannabinoid CB Receptor a Major Regulator of the Neuroinflammatory Axis of the Neurovascular Unit in Humans? Advances in pharmacology (San Diego, Calif.)\| PubMed ID: 28826541	2017
Biosensor Technology Reveals the Disruption of the Endothelial Barrier Function and the Subsequent Death of Blood Brain Barrier Endothelial Cells to Sodium Azide and Its Gaseous Products. Biosensors\| PubMed ID: 28934106	2017
The inflammasome pathway is amplified and perpetuated in an autocrine manner through connexin43 hemichannel mediated ATP release. Biochimica et biophysica acta. General subjects\| PubMed ID: 29158134	2018
The Importance of Multifrequency Impedance Sensing of Endothelial Barrier Formation Using ECIS Technology for the Generation of a Strong and Durable Paracellular Barrier. Biosensors\| PubMed ID: 29973526	2018
The functional and inflammatory response of brain endothelial cells to Toll-Like Receptor agonists. Scientific reports\| PubMed ID: 29973684	2018
In Vitro Wounding Models Using the Electric Cell-Substrate Impedance Sensing (ECIS)-Zθ Technology. Biosensors\| PubMed ID: 30314393	2018
Real-Time Measurement of Melanoma Cell-Mediated Human Brain Endothelial Barrier Disruption Using Electric Cell-Substrate Impedance Sensing Technology. Biosensors\| PubMed ID: 30991758	2019
Evaluation of parylene derivatives for use as biomaterials for human astrocyte cell patterning. PloS one\| PubMed ID: 31237927	2019
Large 10 × 10 single cell grid networks of human hNT astrocytes on raised parylene-C/SiO substrates. Journal of neural engineering\| PubMed ID: 31394515	2019
Bradykinin receptor-1 activation induces inflammation and increases the permeability of human brain microvascular endothelial cells. Cell biology international\| PubMed ID: 31498530	2019
Cannabinoid Receptor 2 (CB) Signals via G-alpha-s and Induces IL-6 and IL-10 Cytokine Secretion in Human Primary Leukocytes. ACS pharmacology & translational science\| PubMed ID: 32259074	2019
Analysis of Melanoma Secretome for Factors That Directly Disrupt the Barrier Integrity of Brain Endothelial Cells. International journal of molecular sciences\| PubMed ID: 33139674	2020
Geometric micro-shapes facilitate trackless connections between human astrocytes. Journal of neural engineering\| PubMed ID: 33601342	2021
Comparison of Leading Biosensor Technologies to Detect Changes in Human Endothelial Barrier Properties in Response to Pro-Inflammatory TNFα and IL1β in Real-Time. Biosensors\| PubMed ID: 34069959	2021
Superior galvanostatic electrochemical deposition of platinum nanograss provides high performance planar microelectrodes forneural recording. Journal of neural engineering\| PubMed ID: 34371484	2021
Can ECIS Biosensor Technology Be Used to Measure the Cellular Responses of Glioblastoma Stem Cells? Biosensors\| PubMed ID: 34940255	2021
Serum biomarkers of neuroinflammation and blood-brain barrier leakage in amyotrophic lateral sclerosis. BMC neurology\| PubMed ID: 35690735	2022
Critical Spatial-Temporal Dynamics and Prominent Shape Collapse of Calcium Waves Observed in Human hNT Astrocytes . Frontiers in physiology\| PubMed ID: 35784870	2022
Comprehensive Assessment of Secreted Immuno-Modulatory Cytokines by Serum-Differentiated and Stem-like Glioblastoma Cells Reveals Distinct Differences between Glioblastoma Phenotypes. International journal of molecular sciences\| PubMed ID: 36430641	2022
Melanoma Cells Produce Large Vesicular-Bodies That Cause Rapid Disruption of Brain Endothelial Barrier-Integrity and Disassembly of Junctional Proteins. International journal of molecular sciences\| PubMed ID: 37047054	2023
The interaction of placental micro-EVs with immune cells in vivo and in vitro. American journal of reproductive immunology (New York, N.Y. : 1989)\| PubMed ID: 37641368	2023