extraction-of-diatom-dna-from-water-samples-and-tissues

Extraction of Diatom DNA from Water Samples and Tissues

Diatom testing is an essential auxiliary means in forensic practice to determine whether the corpse drowned in water and to infer the drowning location. ...

dna-extraction-comparison-between-old-fresh-necrophilic-fly

DNA Extraction and Comparison Between Old and Fresh Necrophilic Fly Samples

A total of five samples of Chrysomya megacephala samples - three fresh samples, one sample stored in alcohol for 2 years, and one sample stored in dry ...

erratum-dna-extraction-comparison-between-old-fresh-necrophilic-fly

Erratum: DNA Extraction and Comparison Between Old and Fresh Necrophilic Fly Samples

This corrects the article ...

ki-67-with-neutrophil-to-lymphocyte-cd4-positivecd8-positive-ratios

Ki-67 with Neutrophil-to-lymphocyte and CD4-positive/CD8-positive Ratios Predicts Early Response in Non-small Cell Lung Cancer

This study evaluated the combined predictive value of tumor Ki-67 expression status, peripheral blood neutrophil-to-lymphocyte ratio (NLR), and the ...

Hainan Vocational College of Political Science and Law

Hainan Gongping Forensic Center

Hainan Medical University, Hainan Provincial Academician Workstation (tropical forensic medicine)

Hainan Gongping Forensic Cente

Binhaiwan Central Hospital of Dongguan

To develop a machine learning model and nomogram to predict the probability of persistent virus shedding (PVS) in hospitalized patients with coronavirus disease 2019 (COVID-19), the clinical symptoms and signs, laboratory parameters, cytokines, and immune cell data of 429 patients with nonsevere COVID-19 were retrospectively reviewed. Two models were developed using the Akaike information criterion (AIC). The performance of these two models was analyzed and compared by the receiver operating characteristic (ROC) curve, calibration curve, net reclassification index (NRI), and integrated discrimination improvement (IDI). The final model included the following independent predictors of PVS: sex, C-reactive protein (CRP) level, interleukin-6 (IL-6) level, the neutrophil-lymphocyte ratio (NLR), monocyte count (MC), albumin (ALB) level, and serum potassium level. The model performed well in both the internal validation (corrected C-statistic = 0.748, corrected Brier score = 0.201) and external validation datasets (corrected C-statistic = 0.793, corrected Brier score = 0.190). The internal calibration was very good (corrected slope = 0.910). The model developed in this study showed high discriminant performance in predicting PVS in nonsevere COVID-19 patients. Because of the availability and accessibility of the model, the nomogram designed in this study could provide a useful prognostic tool for clinicians and medical decision-makers.

ArticleTotal : 4	Year
Publication title Cited by 2	2023
Publication title Cited by 3	2024
Publication title	2024
Publication title	2026

Jie Cai

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