Mark A. Atkinson

Department of Pathology, University of Florida

Affiliated withUniversity of Florida University of Florida

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 32	2012
Publication title Cited by 23	2021

Other Publications

Article	Year
In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow. Diabetes\| PubMed ID: 15220196	2004
Heterophile antibodies segregate in families and are associated with protection from type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 10393957	1999
Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11717448	2001
Microbiology (Reading, England)\| PubMed ID: 11932443	2002
Adeno-associated virus transduction of islets with interleukin-4 results in impaired metabolic function in syngeneic marginal islet mass transplantation. Transplantation\| PubMed ID: 12438968	2002
Fatal attraction: chemokines and type 1 diabetes. The Journal of clinical investigation\| PubMed ID: 12464665	2002
Matrix biology : journal of the International Society for Matrix Biology\| PubMed ID: 12524049	2002
Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice. Diabetes\| PubMed ID: 12606512	2003
Gene delivery in renal tubular epithelial cells using recombinant adeno-associated viral vectors. Journal of the American Society of Nephrology : JASN\| PubMed ID: 12660329	2003
Journal of autoimmunity\| PubMed ID: 12753809	2003
Microbiology (Reading, England)\| PubMed ID: 12777499	2003
Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12928371	2003
American journal of industrial medicine\| PubMed ID: 12929149	2003
Why can't we prevent type 1 diabetes?: maybe it's time to try a different combination. Diabetes care\| PubMed ID: 14633822	2003
Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 15006610	2004
Timing of initial cereal exposure in infancy and risk of islet autoimmunity. The Journal of pediatrics\| PubMed ID: 15152374	2004
Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse. The American journal of pathology\| PubMed ID: 15331427	2004
American journal of industrial medicine\| PubMed ID: 15551364	2004
Diabetes acceleration or prevention by a coxsackievirus B4 infection: critical requirements for both interleukin-4 and gamma interferon. Journal of virology\| PubMed ID: 15613333	2005
Efficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectors. Human gene therapy\| PubMed ID: 15761263	2005
Changes in hippocampal IL-15, related cytokines, and neurogenesis in IL-2 deficient mice. Brain research\| PubMed ID: 15829231	2005
An integral role for heme oxygenase-1 and carbon monoxide in maintaining peripheral tolerance by CD4+CD25+ regulatory T cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15843512	2005
ADA Outstanding Scientific Achievement Lecture 2004. Thirty years of investigating the autoimmune basis for type 1 diabetes: why can't we prevent or reverse this disease? Diabetes\| PubMed ID: 15855308	2005
Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in type 1 diabetes. Diabetes\| PubMed ID: 15855327	2005
Interleukin 10 attenuates neointimal proliferation and inflammation in aortic allografts by a heme oxygenase-dependent pathway. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15878989	2005
Biochemical and biophysical research communications\| PubMed ID: 15882999	2005
Localized gene expression following administration of adeno-associated viral vectors via pancreatic ducts. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 15979413	2005
A comprehensive review of interventions in the NOD mouse and implications for translation. Immunity\| PubMed ID: 16111631	2005
Diabetes\| PubMed ID: 16123339	2005
Systemic overexpression of interleukin-10 fails to protect allogeneic islet transplants in nonobese diabetic mice. Transplantation\| PubMed ID: 16123729	2005
Glucose transporter-2 (GLUT2) promoter mediated transgenic insulin production reduces hyperglycemia in diabetic mice. FEBS letters\| PubMed ID: 16223491	2005
IL-10 suppresses chemokines, inflammation, and fibrosis in a model of chronic renal disease. Journal of the American Society of Nephrology : JASN\| PubMed ID: 16251240	2005
Inhalation toxicology\| PubMed ID: 16282156	2005
Type 1 diabetes mellitus: etiology, presentation, and management. Pediatric clinics of North America\| PubMed ID: 16301083	2005
Diabetes\| PubMed ID: 16380490	2006
Pediatric diabetes\| PubMed ID: 16390385	2005
Efficient delivery of siRNA into cytokine-stimulated insulinoma cells silences Fas expression and inhibits Fas-mediated apoptosis. FEBS letters\| PubMed ID: 16412430	2006
Gene\| PubMed ID: 16412588	2006
Enhanced IgE allergic response to Aspergillus fumigatus in CFTR-/- mice. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 16424881	2006
Uncoupling of vascular endothelial growth factor with nitric oxide as a mechanism for diabetic vasculopathy. Journal of the American Society of Nephrology : JASN\| PubMed ID: 16436494	2006
Role of Pax4 in Pdx1-VP16-mediated liver-to-endocrine pancreas transdifferentiation. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 16732298	2006
Cystic fibrosis transmembrane conductance regulator deficiency exacerbates islet cell dysfunction after beta-cell injury. Diabetes\| PubMed ID: 16804061	2006
Noninvasive imaging of islet grafts using positron-emission tomography. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16868090	2006
Autoantibody markers for the diagnosis and prediction of type 1 diabetes. Autoimmunity reviews\| PubMed ID: 16890898	2006
IL-10 regulation of lupus in the NZM2410 murine model. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 16924244	2006
Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 16982215	2006
Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17114466	2006
Annals of the New York Academy of Sciences\| PubMed ID: 17119209	2006
Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy. Journal of the American Society of Nephrology : JASN\| PubMed ID: 17202420	2007
Annals of the New York Academy of Sciences\| PubMed ID: 17376834	2007
MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. The Journal of experimental medicine\| PubMed ID: 17548519	2007
Immunology\| PubMed ID: 17662044	2007
Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis. Blood\| PubMed ID: 17690255	2007
Novel synthesis of cerium oxide nanoparticles for free radical scavenging. Nanomedicine (London, England)\| PubMed ID: 17716177	2007
Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time-dependent induction of immunoregulation. Diabetes\| PubMed ID: 18039815	2008
Reversal of streptozotocin-induced diabetes in mice by cellular transduction with recombinant pancreatic transcription factor pancreatic duodenal homeobox-1: a novel protein transduction dom... Diabetes\| PubMed ID: 18086901	2008
Neonatal formula feeding leads to immunological alterations in an animal model of type 1 diabetes. Pediatric research\| PubMed ID: 18091354	2008
A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene. Clinical immunology (Orlando, Fla.)\| PubMed ID: 18096436	2008
Assessing the in vitro suppressive capacity of regulatory T cells. Immunological investigations\| PubMed ID: 18161521	2007
Autologous umbilical cord blood infusion for type 1 diabetes. Experimental hematology\| PubMed ID: 18358588	2008
Suppression by CD4+CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigen-presenting cells. The American journal of pathology\| PubMed ID: 18511516	2008
The pivotal role of VEGF on glomerular macrophage infiltration in advanced diabetic nephropathy. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 18607348	2008
CFTR mutations impart elevated immune reactivity in a murine model of cystic fibrosis related diabetes. Cytokine\| PubMed ID: 18778952	2008
The "perfect storm" for type 1 diabetes: the complex interplay between intestinal microbiota, gut permeability, and mucosal immunity. Diabetes\| PubMed ID: 18820210	2008
Murine model for cystic fibrosis bone disease demonstrates osteopenia and sex-related differences in bone formation. Pediatric research\| PubMed ID: 19047917	2009
Expansion of human regulatory T-cells from patients with type 1 diabetes. Diabetes\| PubMed ID: 19074986	2009
Connective tissue research\| PubMed ID: 19085241	2008
Taking a daily vitamin to prevent type 1 diabetes? Diabetes\| PubMed ID: 19114727	2009
Annals of the New York Academy of Sciences\| PubMed ID: 19120260	2008
Annals of the New York Academy of Sciences\| PubMed ID: 19120270	2008
Exendin-4 therapy in NOD mice with new-onset diabetes increases regulatory T cell frequency. Annals of the New York Academy of Sciences\| PubMed ID: 19120286	2008
Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19124749	2009
Exendin-4 treatment of nonobese diabetic mice increases beta-cell proliferation and fractional insulin reactive area. Journal of diabetes and its complications\| PubMed ID: 19217320	2010
Culture-independent identification of gut bacteria correlated with the onset of diabetes in a rat model. The ISME journal\| PubMed ID: 19225551	2009
Lowering blood pressure blocks mesangiolysis and mesangial nodules, but not tubulointerstitial injury, in diabetic eNOS knockout mice. The American journal of pathology\| PubMed ID: 19246639	2009
Rabbit polyclonal mouse antithymocyte globulin administration alters dendritic cell profile and function in NOD mice to suppress diabetogenic responses. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19342635	2009
Influence of fecal sample storage on bacterial community diversity. The open microbiology journal\| PubMed ID: 19440250	2009
The pancreas in human type 1 diabetes: providing new answers to age-old questions. Current opinion in endocrinology, diabetes, and obesity\| PubMed ID: 19502978	2009
Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice. Diabetes\| PubMed ID: 19628781	2009
The road not taken: a path to curing type 1 diabetes? European journal of immunology\| PubMed ID: 19672902	2009
Hepatocellular carcinoma immunopathogenesis: clinical evidence for global T cell defects and an immunomodulatory role for soluble CD25 (sCD25). Digestive diseases and sciences\| PubMed ID: 19714465	2010
Autologous umbilical cord blood transfusion in very young children with type 1 diabetes. Diabetes care\| PubMed ID: 19875605	2009
Influence of membrane CD25 stability on T lymphocyte activity: implications for immunoregulation. PloS one\| PubMed ID: 19956753	2009
Lactobacillus johnsonii N6.2 mitigates the development of type 1 diabetes in BB-DP rats. PloS one\| PubMed ID: 20463897	2010
The pancreas in human type 1 diabetes. Seminars in immunopathology\| PubMed ID: 20495921	2011
The Juvenile Diabetes Research Foundation at forty: updates of research in type 1 diabetes. Diabetes\| PubMed ID: 20587801	2010
Toward defining the autoimmune microbiome for type 1 diabetes. The ISME journal\| PubMed ID: 20613793	2011
Human antigen-specific regulatory T cells generated by T cell receptor gene transfer. PloS one\| PubMed ID: 20668510	2010
Butyrate and type 1 diabetes mellitus: can we fix the intestinal leak? Journal of pediatric gastroenterology and nutrition\| PubMed ID: 20706153	2010
Type I diabetes. Preface. Endocrinology and metabolism clinics of North America\| PubMed ID: 20723814	2010
Efforts to prevent and halt autoimmune beta cell destruction. Endocrinology and metabolism clinics of North America\| PubMed ID: 20723818	2010
Influence of serum and soluble CD25 (sCD25) on regulatory and effector T-cell function in hepatocellular carcinoma. Scandinavian journal of immunology\| PubMed ID: 20883314	2010
It's time to consider changing the rules: the rationale for rethinking control groups in clinical trials aimed at reversing type 1 diabetes. Diabetes\| PubMed ID: 21270247	2011
Inhibition of type 1 diabetes correlated to a Lactobacillus johnsonii N6.2-mediated Th17 bias. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21317395	2011
Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model. Journal of translational medicine\| PubMed ID: 21345239	2011
Persistence is the twin sister of excellence: an important lesson for attempts to prevent and reverse type 1 diabetes. Diabetes\| PubMed ID: 21357468	2011
Multimodality imaging of β-cells in mouse models of type 1 and 2 diabetes. Diabetes\| PubMed ID: 21441442	2011
How does type 1 diabetes develop?: the notion of homicide or Î²-cell suicide revisited. Diabetes\| PubMed ID: 21525508	2011
Progressive erosion of Î²-cell function precedes the onset of hyperglycemia in the NOD mouse model of type 1 diabetes. Diabetes\| PubMed ID: 21659497	2011
B cells enhance early innate immune responses during bacterial sepsis. The Journal of experimental medicine\| PubMed ID: 21746813	2011
Evaluating preclinical efficacy. Science translational medicine\| PubMed ID: 21849661	2011
Loss of intra-islet CD20 expression may complicate efficacy of B-cell-directed type 1 diabetes therapies. Diabetes\| PubMed ID: 21926271	2011
Hyperglycemia-induced proliferation of adult human beta cells engrafted into spontaneously diabetic immunodeficient NOD-Rag1null IL2rγnull Ins2Akita mice. Pancreas\| PubMed ID: 21926555	2011
Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptide. Diabetes care\| PubMed ID: 22011412	2011
It's time to mow the GRAS in type 1 diabetes. Diabetes\| PubMed ID: 22025772	2011
Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22043012	2011
Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes. PloS one\| PubMed ID: 22043294	2011
Central role for interleukin-2 in type 1 diabetes. Diabetes\| PubMed ID: 22187370	2012
Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients. The Journal of experimental medicine\| PubMed ID: 22213807	2012
Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice. The Journal of clinical investigation\| PubMed ID: 22484814	2012
Formation of a human Î²-cell population within pancreatic islets is set early in life. The Journal of clinical endocrinology and metabolism\| PubMed ID: 22745242	2012
In vitro generation of functional insulin-producing cells from human bone marrow-derived stem cells, but long-term culture running risk of malignant transformation. American journal of stem cells\| PubMed ID: 22833839	2012
The pathogenesis and natural history of type 1 diabetes. Cold Spring Harbor perspectives in medicine\| PubMed ID: 23125199	2012
Serum levels of soluble CD25 as a marker for hepatocellular carcinoma. Oncology letters\| PubMed ID: 23205111	2012
Immune modulation of effector CD4+ and regulatory T cell function by sorafenib in patients with hepatocellular carcinoma. Cancer immunology, immunotherapy : CII\| PubMed ID: 23223899	2013
Pancreas organ weight in individuals with disease-associated autoantibodies at risk for type 1 diabetes. JAMA\| PubMed ID: 23232891	2012
Anti-thymocyte globulin (ATG) differentially depletes naïve and memory T cells and permits memory-type regulatory T cells in nonobese diabetic mice. BMC immunology\| PubMed ID: 23237483	2012
Recent lessons learned from prevention and recent-onset type 1 diabetes immunotherapy trials. Diabetes\| PubMed ID: 23258904	2013
Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes. The Journal of experimental medicine\| PubMed ID: 23277452	2013
The granulocyte colony stimulating factor pathway regulates autoantibody production in a murine induced model of systemic lupus erythematosus. Arthritis research & therapy\| PubMed ID: 23566364	2013
Autologous umbilical cord blood infusion followed by oral docosahexaenoic acid and vitamin D supplementation for C-peptide preservation in children with Type 1 diabetes. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 23611977	2013
Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function. Diabetes\| PubMed ID: 23835340	2013
Type 1 diabetes. Lancet (London, England)\| PubMed ID: 23890997	2014
The autoimmune disease-associated SNP rs917997 of IL18RAP controls IFNγ production by PBMC. Journal of autoimmunity\| PubMed ID: 23891168	2013
Global reality of type 1 diabetes care in 2013. Diabetes care\| PubMed ID: 23970723	2013
GABA regulates both the survival and replication of human ss-cells. Diabetes\| PubMed ID: 23995958	2013
The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) Program: goals, operational model and emerging findings. Pediatric diabetes\| PubMed ID: 24325575	2014
Pancreatic biopsies in type 1 diabetes: revisiting the myth of Pandora's box. Diabetologia\| PubMed ID: 24442510	2014
Improving diabetes care in resource-poor countries: challenges and opportunities. The lancet. Diabetes & endocrinology\| PubMed ID: 24622408	2013
Oral delivery of glutamic acid decarboxylase (GAD)-65 and IL10 by Lactococcus lactis reverses diabetes in recent-onset NOD mice. Diabetes\| PubMed ID: 24677716	2014
Increased IFN-α-producing plasmacytoid dendritic cells (pDCs) in human Th1-mediated type 1 diabetes: pDCs augment Th1 responses through IFN-α production. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24973447	2014
New insight on human type 1 diabetes biology: nPOD and nPOD-transplantation. Current diabetes reports\| PubMed ID: 25142715	2014
Losing a grip on the notion of β-cell specificity for immune responses in type 1 diabetes: can we handle the truth? Diabetes\| PubMed ID: 25342726	2014
Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes. The Journal of clinical investigation\| PubMed ID: 25500887	2015
Stem cells to insulin secreting cells: two steps forward and now a time to pause? Cell stem cell\| PubMed ID: 25517460	2014
Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes. Diabetes care\| PubMed ID: 25519450	2015
Bacteroides dorei dominates gut microbiome prior to autoimmunity in Finnish children at high risk for type 1 diabetes. Frontiers in microbiology\| PubMed ID: 25540641	2014
Beta-cell destruction and preservation in childhood and adult onset type 1 diabetes. Endocrine\| PubMed ID: 25605478	2015
The streetlight effect in type 1 diabetes. Diabetes\| PubMed ID: 25805758	2015
A combination dual-sized microparticle system modulates dendritic cells and prevents type 1 diabetes in prediabetic NOD mice. Clinical immunology (Orlando, Fla.)\| PubMed ID: 25842187	2015
Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25994968	2015
Current concepts on the pathogenesis of type 1 diabetes--considerations for attempts to prevent and reverse the disease. Diabetes care\| PubMed ID: 25998290	2015
A run on the biobank: what have we learned about type 1 diabetes from the nPOD tissue repository? Current opinion in endocrinology, diabetes, and obesity\| PubMed ID: 26087339	2015
Combination Therapy Reverses Hyperglycemia in NOD Mice With Established Type 1 Diabetes. Diabetes\| PubMed ID: 26185279	2015
Acute Versus Progressive Onset of Diabetes in NOD Mice: Potential Implications for Therapeutic Interventions in Type 1 Diabetes. Diabetes\| PubMed ID: 26216853	2015
The role for gut permeability in the pathogenesis of type 1 diabetes--a solid or leaky concept? Pediatric diabetes\| PubMed ID: 26269193	2015
A combination hydrogel microparticle-based vaccine prevents type 1 diabetes in non-obese diabetic mice. Scientific reports\| PubMed ID: 26279095	2015
The influence of type 1 diabetes on pancreatic weight. Diabetologia\| PubMed ID: 26358584	2016
Staging presymptomatic type 1 diabetes: a scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association. Diabetes care\| PubMed ID: 26404926	2015
Immune Depletion in Combination with Allogeneic Islets Permanently Restores Tolerance to Self-Antigens in Diabetic NOD Mice. PloS one\| PubMed ID: 26580221	2015
Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes. Diabetes\| PubMed ID: 26581594	2016
A Preclinical Consortium Approach for Assessing the Efficacy of Combined Anti-CD3 Plus IL-1 Blockade in Reversing New-Onset Autoimmune Diabetes in NOD Mice. Diabetes\| PubMed ID: 26718498	2016
Pancreatic duct hyperplasia/dysplasia in type 1 diabetes and pancreatic weight in individuals with and without diabetes. Reply to Kobayashi T, Aida K, Fukui T et al [letter] and Saisho Y [le... Diabetologia\| PubMed ID: 26861059	2016
Type 1 diabetes cadaveric human pancreata exhibit a unique exocrine tissue proteomic profile. Proteomics\| PubMed ID: 26935967	2016
Sulfatide Preserves Insulin Crystals Not by Being Integrated in the Lattice but by Stabilizing Their Surface. Journal of diabetes research\| PubMed ID: 26981544	2016
Presumptive Type 1 Diabetes With Comorbidities and Rapid Progression Despite Numerous Insulin-Positive Islets. Diabetes care\| PubMed ID: 27330131	2016
Aberrant Menin expression is an early event in pancreatic neuroendocrine tumorigenesis. Human pathology\| PubMed ID: 27342911	2016
Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes. Diabetologia\| PubMed ID: 27506584	2016
Antithymocyte Globulin Plus G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders With Established Type 1 Diabetes. Diabetes\| PubMed ID: 27669730	2016
Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity. Diabetologia\| PubMed ID: 27785529	2017
Autoimmune manifestations in aged mice arise from early-life immune dysregulation. Science translational medicine\| PubMed ID: 27798262	2016
Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nature medicine\| PubMed ID: 27798614	2016
Islet-derived CD4 T-cells targeting proinsulin in human autoimmune diabetes. Diabetes\| PubMed ID: 27920090	2016
Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes. JCI insight\| PubMed ID: 27942583	2016
Type 1 Diabetes Prevention: A Goal Dependent on Accepting a Diagnosis of an Asymptomatic Disease. Diabetes\| PubMed ID: 27959859	2016
Factors That Influence the Quality of RNA From the Pancreas of Organ Donors. Pancreas\| PubMed ID: 27984510	2017
Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Diabetologia\| PubMed ID: 28070616	2017
Serum Trypsinogen Levels in Type 1 Diabetes. Diabetes care\| PubMed ID: 28115475	2017
Plant-based vaccines for oral delivery of type 1 diabetes-related autoantigens: Evaluating oral tolerance mechanisms and disease prevention in NOD mice. Scientific reports\| PubMed ID: 28205558	2017
Expansion of Human Tregs from Cryopreserved Umbilical Cord Blood for GMP-Compliant Autologous Adoptive Cell Transfer Therapy. Molecular therapy. Methods & clinical development\| PubMed ID: 28345003	2017
Genetic and Small Molecule Disruption of the AID/RAD51 Axis Similarly Protects Nonobese Diabetic Mice from Type 1 Diabetes through Expansion of Regulatory B Lymphocytes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 28461573	2017
Mary Tyler Moore (1936-2017): Diabetes Educator and Advocate. Diabetes care\| PubMed ID: 28533256	2017
Comparative Pathogenesis of Autoimmune Diabetes in Humans, NOD Mice, and Canines: Has a Valuable Animal Model of Type 1 Diabetes Been Overlooked? Diabetes\| PubMed ID: 28533295	2017
N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults. Frontiers in immunology\| PubMed ID: 28659913	2017
High Illicit Drug Abuse and Suicide in Organ Donors With Type 1 Diabetes. Diabetes care\| PubMed ID: 28679687	2017
Impact of blood collection and processing on peripheral blood gene expression profiling in type 1 diabetes. BMC genomics\| PubMed ID: 28821222	2017
Untargeted metabolomic analysis in naturally occurring canine diabetes mellitus identifies similarities to human Type 1 Diabetes. Scientific reports\| PubMed ID: 28842637	2017
Dysglycemia and Index60 as Prediagnostic End Points for Type 1 Diabetes Prevention Trials. Diabetes care\| PubMed ID: 28860125	2017
Proteoliposome-based full-length ZnT8 self-antigen for type 1 diabetes diagnosis on a plasmonic platform. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28874568	2017
Type 1 Interferons Potentiate Human CD8 T-Cell Cytotoxicity Through a STAT4- and Granzyme B-Dependent Pathway. Diabetes\| PubMed ID: 28877912	2017
T cells display mitochondria hyperpolarization in human type 1 diabetes. Scientific reports\| PubMed ID: 28883439	2017
Pancreatic Histopathology of Human Monogenic Diabetes Due to Causal Variants in KCNJ11, HNF1A, GATA6, and LMNA. The Journal of clinical endocrinology and metabolism\| PubMed ID: 28938416	2018
Disease-specific biases in alternative splicing and tissue-specific dysregulation revealed by multitissue profiling of lymphocyte gene expression in type 1 diabetes. Genome research\| PubMed ID: 29025893	2017
Association Between Early-Life Antibiotic Use and the Risk of Islet or Celiac Disease Autoimmunity. JAMA pediatrics\| PubMed ID: 29052687	2017
Transient BAFF Blockade Inhibits Type 1 Diabetes Development in Nonobese Diabetic Mice by Enriching Immunoregulatory B Lymphocytes Sensitive to Deletion by Anti-CD20 Cotherapy. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 29055002	2017
Hospital time prior to death and pancreas histopathology: implications for future studies. Diabetologia\| PubMed ID: 29128936	2018
Loss of B-Cell Anergy in Type 1 Diabetes Is Associated With High-Risk HLA and Non-HLA Disease Susceptibility Alleles. Diabetes\| PubMed ID: 29343548	2018
Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes. The Journal of clinical investigation\| PubMed ID: 29438107	2018
Type 1 Diabetes TrialNet: A Multifaceted Approach to Bringing Disease-Modifying Therapy to Clinical Use in Type 1 Diabetes. Diabetes care\| PubMed ID: 29559451	2018
Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience. Diabetes\| PubMed ID: 29769238	2018
Islet Microvasculature Alterations With Loss of Beta-cells in Patients With Type 1 Diabetes. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 29771178	2019
Protective Role of Myeloid Cells Expressing a G-CSF Receptor Polymorphism in an Induced Model of Lupus. Frontiers in immunology\| PubMed ID: 29868014	2018
Low-Dose Anti-Thymocyte Globulin (ATG) Preserves β-Cell Function and Improves HbA in New-Onset Type 1 Diabetes. Diabetes care\| PubMed ID: 30012675	2018
Islet-Derived eATP Fuels Autoreactive CD8 T Cells and Facilitates the Onset of Type 1 Diabetes. Diabetes\| PubMed ID: 30065030	2018
Nanowell-mediated two-dimensional liquid chromatography enables deep proteome profiling of <1000 mammalian cells. Chemical science\| PubMed ID: 30210768	2018
Transcription Factor 7-Like 2 () Gene Polymorphism and Progression From Single to Multiple Autoantibody Positivity in Individuals at Risk for Type 1 Diabetes. Diabetes care\| PubMed ID: 30275285	2018
The challenge of modulating β-cell autoimmunity in type 1 diabetes. The lancet. Diabetes & endocrinology\| PubMed ID: 30528099	2019
Relative Pancreas Volume Is Reduced in First-Degree Relatives of Patients With Type 1 Diabetes. Diabetes care\| PubMed ID: 30552130	2019
Type 1 Diabetes Risk in African-Ancestry Participants and Utility of an Ancestry-Specific Genetic Risk Score. Diabetes care\| PubMed ID: 30659077	2019
Rationale for enteroviral vaccination and antiviral therapies in human type 1 diabetes. Diabetologia\| PubMed ID: 30675626	2019
Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas. Frontiers in endocrinology\| PubMed ID: 30687234	2018
A Map of Human Type 1 Diabetes Progression by Imaging Mass Cytometry. Cell metabolism\| PubMed ID: 30713109	2019
Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes. Cell metabolism\| PubMed ID: 30713110	2019
Trying to make a difference for those with Type 1 diabetes: a lesson in patience as well as a willingness to fail mightily. Expert review of endocrinology & metabolism\| PubMed ID: 30736146	2013
Boosting to Amplify Signal with Isobaric Labeling (BASIL) Strategy for Comprehensive Quantitative Phosphoproteomic Characterization of Small Populations of Cells. Analytical chemistry\| PubMed ID: 30843680	2019
Increased risk for T cell autoreactivity to ß-cell antigens in the mice expressing the A obesity-associated gene. Scientific reports\| PubMed ID: 30862859	2019
Low-Dose Anti-Thymocyte Globulin Preserves C-Peptide, Reduces HbA, and Increases Regulatory to Conventional T-Cell Ratios in New-Onset Type 1 Diabetes: Two-Year Clinical Trial Data. Diabetes\| PubMed ID: 30967424	2019
Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence. Reply to Skog O, Klingel K, Roivainen M et al [letter]. Diabetologia\| PubMed ID: 31016358	2019
Islet amyloidosis in a child with type 1 diabetes. Islets\| PubMed ID: 31084520	2019
Dual-Sized Microparticle System for Generating Suppressive Dendritic Cells Prevents and Reverses Type 1 Diabetes in the Nonobese Diabetic Mouse Model. ACS biomaterials science & engineering\| PubMed ID: 31119191	2019
NIH Initiative to Improve Understanding of the Pancreas, Islet, and Autoimmunity in Type 1 Diabetes: The Human Pancreas Analysis Program (HPAP). Diabetes\| PubMed ID: 31127054	2019
Pleiotropic roles of the insulin-like growth factor axis in type 1 diabetes. Current opinion in endocrinology, diabetes, and obesity\| PubMed ID: 31145130	2019
The Influence of Type 2 Diabetes-Associated Factors on Type 1 Diabetes. Diabetes care\| PubMed ID: 31167894	2019
Genetic risk for autoimmunity is associated with distinct changes in the human gut microbiome. Nature communications\| PubMed ID: 31399563	2019
Regulated hAAT Expression from a Novel rAAV Vector and Its Application in the Prevention of Type 1 Diabetes. Journal of clinical medicine\| PubMed ID: 31466263	2019
Who Is Enrolling? The Path to Monitoring in Type 1 Diabetes TrialNet's Pathway to Prevention. Diabetes care\| PubMed ID: 31558546	2019
Temporal Analysis of Amylase Expression in Control, Autoantibody-Positive, and Type 1 Diabetes Pancreatic Tissues. Diabetes\| PubMed ID: 31597639	2020
Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes. Diabetes care\| PubMed ID: 31753960	2020
The risk of progression to type 1 diabetes is highly variable in individuals with multiple autoantibodies following screening. Diabetologia\| PubMed ID: 31768570	2020
Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation. Cell reports\| PubMed ID: 31801074	2019
Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis. Diabetes\| PubMed ID: 31826866	2020
Single Islet Autoantibody at Diagnosis of Clinical Type 1 Diabetes is Associated With Older Age and Insulin Resistance. The Journal of clinical endocrinology and metabolism\| PubMed ID: 31867614	2020
Early and late C-peptide responses during oral glucose tolerance testing are oppositely predictive of type 1 diabetes in autoantibody-positive individuals. Diabetes, obesity & metabolism\| PubMed ID: 32003110	2020
Innate inflammation drives NK cell activation to impair Treg activity. Journal of autoimmunity\| PubMed ID: 32035746	2020
Obesity Treatment Among Adolescents: A Review of Current Evidence and Future Directions. JAMA pediatrics\| PubMed ID: 32202626	2020
Commercially Available Insulin Products Demonstrate Stability Throughout the Cold Supply Chain Across the U.S. Diabetes care\| PubMed ID: 32273273	2020
Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis. JCI insight\| PubMed ID: 32324170	2020
Large-scale electron microscopy database for human type 1 diabetes. Nature communications\| PubMed ID: 32424134	2020
Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic β cells. JCI insight\| PubMed ID: 32573495	2020
Intestinal Delivery of Proinsulin and IL-10 via Combined With Low-Dose Anti-CD3 Restores Tolerance Outside the Window of Acute Type 1 Diabetes Diagnosis. Frontiers in immunology\| PubMed ID: 32582188	2020
Removing Formaldehyde-Induced Peptidyl Crosslinks Enables Mass Spectrometry Imaging of Peptide Hormone Distributions from Formalin-Fixed Paraffin-Embedded Tissues. Angewandte Chemie (International ed. in English)\| PubMed ID: 32762062	2020
Comparing Beta Cell Preservation Across Clinical Trials in Recent-Onset Type 1 Diabetes. Diabetes technology & therapeutics\| PubMed ID: 32833543	2020
Organisation of the human pancreas in health and in diabetes. Diabetologia\| PubMed ID: 32894306	2020
CD226 Deletion Reduces Type 1 Diabetes in the NOD Mouse by Impairing Thymocyte Development and Peripheral T Cell Activation. Frontiers in immunology\| PubMed ID: 33013915	2020
Immunomodulatory Dual-Sized Microparticle System Conditions Human Antigen Presenting Cells Into a Tolerogenic Phenotype and Inhibits Type 1 Diabetes-Specific Autoreactive T Cell Responses. Frontiers in immunology\| PubMed ID: 33193362	2020
Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19. Cell metabolism\| PubMed ID: 33207244	2020
Pancreatlas: Applying an Adaptable Framework to Map the Human Pancreas in Health and Disease. Patterns (New York, N.Y.)\| PubMed ID: 33294866	2020
Image-Based Machine Learning Algorithms for Disease Characterization in the Human Type 1 Diabetes Pancreas. The American journal of pathology\| PubMed ID: 33307036	2021
Evaluation for type 1 diabetes associated autoantibodies in diabetic and non-diabetic Australian terriers and Samoyeds. Canine medicine and genetics\| PubMed ID: 33323126	2020
Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis. Diabetes\| PubMed ID: 33419759	2021
Exocrine Pancreatic Enzymes Are a Serological Biomarker for Type 1 Diabetes Staging and Pancreas Size. Diabetes\| PubMed ID: 33441381	2021
Exocrine Pancreas Dysfunction in Type 1 Diabetes. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists\| PubMed ID: 33471743	2020
Modulation of Leukocytes of the Innate Arm of the Immune System as a Potential Approach to Prevent the Onset and Progression of Type 1 Diabetes. Diabetes\| PubMed ID: 33472941	2021
Integrative analyses of TEDDY Omics data reveal lipid metabolism abnormalities, increased intracellular ROS and heightened inflammation prior to autoimmunity for type 1 diabetes. Genome biology\| PubMed ID: 33478573	2021
Index60 as an additional diagnostic criterion for type 1 diabetes. Diabetologia\| PubMed ID: 33496819	2021
Interleukin-27 is essential for type 1 diabetes development and Sjögren syndrome-like inflammation. Cell reports\| PubMed ID: 33535031	2021
TCR/BCR dual-expressing cells and their associated public BCR clonotype are not enriched in type 1 diabetes. Cell\| PubMed ID: 33545036	2021
Low-dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report. Diabetes\| PubMed ID: 33632742	2021
Insulin Receptor-Expressing T Cells Appear in Individuals at Risk for Type 1 Diabetes and Can Move into the Pancreas in C57BL/6 Transgenic Mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 33658296	2021
Islet sympathetic innervation and islet neuropathology in patients with type 1 diabetes. Scientific reports\| PubMed ID: 33753784	2021
Distinguishing the real from the hyperglycaemia: does COVID-19 induce diabetes? The lancet. Diabetes & endocrinology\| PubMed ID: 33838106	2021