Shaf Keshavjee

Latner Thoracic Research Laboratories, University Health Network

Affiliated withUniversity Health Network University of Toronto

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2023

Other Publications

Article	Year
A novel minimally invasive near-infrared thoracoscopic localization technique of small pulmonary nodules: A phase I feasibility trial. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 28495056	2017
Stability and heterogeneity of expression profiles in lung cancer specimens harvested following surgical resection. Neoplasia (New York, N.Y.)\| PubMed ID: 15720802	2004
Organ donor management in Canada: recommendations of the forum on Medical Management to Optimize Donor Organ Potential. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne\| PubMed ID: 16534070	2006
The early responses of VEGF and its receptors during acute lung injury: implication of VEGF in alveolar epithelial cell survival. Critical care (London, England)\| PubMed ID: 16968555	2006
Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome. Journal of virology\| PubMed ID: 17537853	2007
Functions of type II pneumocyte-derived vascular endothelial growth factor in alveolar structure, acute inflammation, and vascular permeability. The American journal of pathology\| PubMed ID: 20167862	2010
XB130, a novel adaptor protein, promotes thyroid tumor growth. The American journal of pathology\| PubMed ID: 21224076	2011
Regression of allograft airway fibrosis: the role of MMP-dependent tissue remodeling in obliterative bronchiolitis after lung transplantation. The American journal of pathology\| PubMed ID: 21763265	2011
Induction of immunological tolerance towards adenoviral vectors using a novel dendritic cell-based strategy. Journal of virology\| PubMed ID: 22258241	2012
Pulmonary bacterial communities in surgically resected noncystic fibrosis bronchiectasis lungs are similar to those in cystic fibrosis. Pulmonary medicine\| PubMed ID: 22448327	2012
Claudin 1 mediates TNFα-induced gene expression and cell migration in human lung carcinoma cells. PloS one\| PubMed ID: 22675434	2012
Protective effects of long pentraxin PTX3 on lung injury in a severe acute respiratory syndrome model in mice. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 22732935	2012
A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22853952	2012
XB130 mediates cancer cell proliferation and survival through multiple signaling events downstream of Akt. PloS one\| PubMed ID: 22928011	2012
Analysis of the cystic fibrosis lung microbiota via serial Illumina sequencing of bacterial 16S rRNA hypervariable regions. PloS one\| PubMed ID: 23056217	2012
XB130, a new adaptor protein, regulates expression of tumor suppressive microRNAs in cancer cells. PloS one\| PubMed ID: 23527086	2013
A novel minimally invasive technique to create a rabbit VX2 lung tumor model for nano-sized image contrast and interventional studies. PloS one\| PubMed ID: 23840673	2013
Bone marrow-derived progenitor cells in end-stage lung disease patients. BMC pulmonary medicine\| PubMed ID: 23915095	2013
Elevated CXCL10 (IP-10) in bronchoalveolar lavage fluid is associated with acute cellular rejection after human lung transplantation. Transplantation\| PubMed ID: 24025324	2014
Efficient gene delivery to pig airway epithelia and submucosal glands using helper-dependent adenoviral vectors. Molecular therapy. Nucleic acids\| PubMed ID: 24104599	2013
Overview of clinical lung transplantation. Cold Spring Harbor perspectives in medicine\| PubMed ID: 24384816	2014
Metabolomic heterogeneity of pulmonary arterial hypertension. PloS one\| PubMed ID: 24533144	2014
XB130 deficiency affects tracheal epithelial differentiation during airway repair. PloS one\| PubMed ID: 25272040	2014
De novo synthesize of bile acids in pulmonary arterial hypertension lung. Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 25374487	2014
Thymectomy for non-thymomatous myasthenia gravis: a propensity score matched study. Orphanet journal of rare diseases\| PubMed ID: 25539860	2014
Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell c... Respiratory research\| PubMed ID: 25551685	2014
Impact of CLAD Phenotype on Survival After Lung Retransplantation: A Multicenter Study. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 25940517	2015
Minimally invasive electro-magnetic navigational bronchoscopy-integrated near-infrared-guided sentinel lymph node mapping in the porcine lung. PloS one\| PubMed ID: 25993006	2015
Phenotypic diversity within a Pseudomonas aeruginosa population infecting an adult with cystic fibrosis. Scientific reports\| PubMed ID: 26047320	2015
A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung. PloS one\| PubMed ID: 26317340	2015
Fractal circuit sensors enable rapid quantification of biomarkers for donor lung assessment for transplantation. Science advances\| PubMed ID: 26601233	2015
Video-assisted transcervical thymectomy for myasthenia gravis. Annals of cardiothoracic surgery\| PubMed ID: 26693155	2015
Pulmonary vascular changes 22 years after single lung transplantation for pulmonary arterial hypertension: a case report with molecular and pathological analysis. Pulmonary circulation\| PubMed ID: 26697185	2015
Clinical role of a new prognostic score using platelet-to-lymphocyte ratio in patients with malignant pleural mesothelioma undergoing extrapleural pneumonectomy. Journal of thoracic disease\| PubMed ID: 26716028	2015
A window of opportunity study of potential tumor and soluble biomarkers of response to preoperative erlotinib in early stage non-small cell lung cancer. Oncotarget\| PubMed ID: 27028852	2016
An Integrated Nanotechnology-Enabled Transbronchial Image-Guided Intervention Strategy for Peripheral Lung Cancer. Cancer research\| PubMed ID: 27543602	2016
SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis. PLoS biology\| PubMed ID: 27880766	2016
Pulmonary and atrial resection and reconstruction for sarcoma with intracardiac extension. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 28089645	2017
Sevoflurane Attenuates Ischemia-Reperfusion Injury in a Rat Lung Transplantation Model. The Annals of thoracic surgery\| PubMed ID: 28190546	2017
High Risk for Thoracotomy but not Thoracoscopic Lobectomy. The Annals of thoracic surgery\| PubMed ID: 28262299	2017
Cost-effectiveness of mediastinal lymph node staging in non-small cell lung cancer. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 28283236	2017
Impact of tumour thickness on survival after radical radiation and surgery in malignant pleural mesothelioma. The European respiratory journal\| PubMed ID: 28298401	2017
The American Association for Thoracic Surgery/Society of Thoracic Surgeons position statement on developing clinical practice documents. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 28359374	2017
The American Association for Thoracic Surgery/Society of Thoracic Surgeons Position Statement on Developing Clinical Practice Documents. The Annals of thoracic surgery\| PubMed ID: 28359472	2017
Pentraxin 3 levels in bronchoalveolar lavage fluid of lung transplant recipients with invasive aspergillosis. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 28487045	2017
Chest Wall Resection for Recurrent Breast Cancer in the Modern Era: A Systematic Review and Meta-analysis. Annals of surgery\| PubMed ID: 28654540	2018
The role of biomechanical anatomical modeling via computed tomography for identification of restrictive allograft syndrome. Clinical transplantation\| PubMed ID: 28658530	2017
Higher M30 and high mobility group box 1 protein levels in ex vivo lung perfusate are associated with primary graft dysfunction after human lung transplantation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 28689646	2017
Development of a novel porcine laparoscopic Heller myotomy and Nissen fundoplication training model (Toronto lap-Nissen simulator). Journal of thoracic disease\| PubMed ID: 28740664	2017
Extracorporeal support in airway surgery. Journal of thoracic disease\| PubMed ID: 28840012	2017
Metabolic heterogeneity of idiopathic pulmonary fibrosis: a metabolomic study. BMJ open respiratory research\| PubMed ID: 28883924	2017
Performance of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration for the Diagnosis of Isolated Mediastinal and Hilar Lymphadenopathy. Respiration; international review of thoracic diseases\| PubMed ID: 28898881	2017
α-Anti-trypsin improves function of porcine donor lungs during ex-vivo lung perfusion. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 29153638	2018
Utility of transthoracic needle biopsy after lung transplantation. Clinical transplantation\| PubMed ID: 29194758	2018
Metabolic Profile of Ex Vivo Lung Perfusate Yields Biomarkers for Lung Transplant Outcomes. Annals of surgery\| PubMed ID: 29240608	2018
Extracorporeal life support as a bridge to lung transplantation-experience of a high-volume transplant center. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 29248282	2018
Lung in a Box: Ex Vivo Lung Transplantation. Journal of cardiothoracic and vascular anesthesia\| PubMed ID: 29449154	2018
Effects of Warm Versus Cold Ischemic Donor Lung Preservation on the Underlying Mechanisms of Injuries During Ischemia and Reperfusion. Transplantation\| PubMed ID: 29470355	2018
Pentraxin 3 deficiency enhances features of chronic rejection in a mouse orthotopic lung transplantation model. Oncotarget\| PubMed ID: 29492210	2018
A strategy for prevention of fungal infections in lung transplantation: Role of bronchoalveolar lavage fluid galactomannan and fungal culture. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 29548625	2018
Upregulation of alveolar neutrophil enzymes and long pentraxin-3 in human chronic lung allograft dysfunction subtypes. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 29573785	2018
Efficacy and Cost of Awake Thoracoscopy and Video-Assisted Thoracoscopic Surgery in the Undiagnosed Pleural Effusion. The Annals of thoracic surgery\| PubMed ID: 29577922	2018
miR-145 expression enhances integrin expression in SK-GT-4 cell line by down-regulating c-Myc expression. Oncotarget\| PubMed ID: 29632636	2018
Quantitative chest CT for subtyping chronic lung allograft dysfunction and its association with survival. Clinical transplantation\| PubMed ID: 29637624	2018
Comprehensive outcomes after lung retransplantation: A single-center review. Clinical transplantation\| PubMed ID: 29754418	2018
Sequential broncho-alveolar lavages reflect distinct pulmonary compartments: clinical and research implications in lung transplantation. Respiratory research\| PubMed ID: 29801490	2018
Inhibition of regulated necrosis attenuates receptor-interacting protein kinase 1-mediated ischemia-reperfusion injury after lung transplantation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 29907500	2018
Visualizing Heterogeneous Pulmonary Ventilation. Respiratory Failure due to an Anterior Mediastinal Mass. American journal of respiratory and critical care medicine\| PubMed ID: 29924939	2018
A novel combined ex vivo and in vivo lentiviral interleukin-10 gene delivery strategy at the time of transplantation decreases chronic lung allograft rejection in mice. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 29937159	2018
Introducing the concept of semielective lung transplantation through the use of ex vivo lung perfusion. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 29961586	2018
Ischemia-reperfusion induces death receptor-independent necroptosis via calpain-STAT3 activation in a lung transplant setting. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 30024306	2018
Pig lung transplant survival model. Nature protocols\| PubMed ID: 30072720	2018
Favourable health-related quality of life reported in survivors of thymic malignancies. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 30084958	2019
Incidence of primary graft dysfunction after lung transplantation is altered by timing of allograft implantation. Thorax\| PubMed ID: 30301818	2019
Porphyrin-High-Density Lipoprotein: A Novel Photosensitizing Nanoparticle for Lung Cancer Therapy. The Annals of thoracic surgery\| PubMed ID: 30316853	2019
Echinocandin use in lung transplant recipients. Clinical transplantation\| PubMed ID: 30375050	2018
Spectrum of chronic lung allograft pathology in a mouse minor-mismatched orthotopic lung transplant model. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 30378739	2019
Neutrophil extracellular traps in lung perfusion perfusate predict the clinical outcome of lung transplant recipients. The European respiratory journal\| PubMed ID: 30655281	2019
Lentiviral interleukin-10 gene therapy: Safety and questions. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 30669243	2019
Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion. Nature communications\| PubMed ID: 30696822	2019
CT-guided Microcoil Pulmonary Nodule Localization prior to Video-assisted Thoracoscopic Surgery: Diagnostic Utility and Recurrence-Free Survival. Radiology\| PubMed ID: 30720402	2019
Cytokine profile in lung transplant recipients with Aspergillus spp colonization. Transplant infectious disease : an official journal of the Transplantation Society\| PubMed ID: 30753747	2019
Molecular assessment of rejection and injury in lung transplant biopsies. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 30773443	2019
3D Models in the Diagnosis of Subglottic Airway Stenosis. The Annals of thoracic surgery\| PubMed ID: 30825452	2019
Donor prone positioning protects lungs from injury during warm ischemia. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 30887696	2019
Uniportal Video-Assisted Transcervical Thymectomy. Thoracic surgery clinics\| PubMed ID: 30928000	2019
Endobronchial ultrasound-guided transbronchial needle aspiration mediastinal lymph node staging in malignant pleural mesothelioma. Journal of thoracic disease\| PubMed ID: 30963005	2019
Chronic meningitis in a lung transplant recipient. Medical mycology case reports\| PubMed ID: 30976504	2019
Epithelial cell death markers in bronchoalveolar lavage correlate with chronic lung allograft dysfunction subtypes and survival in lung transplant recipients-a single-center retrospective co... Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 31002407	2019
Veno-venous extracorporeal life support for blastomycosis-associated acute respiratory distress syndrome. Perfusion\| PubMed ID: 31027465	2019
A successful lung transplant from a 3-year-old donor after controlled cardiac death followed by ex vivo lung perfusion: A case report. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 31126646	2019
Donor human leukocyte antigen-G single nucleotide polymorphisms are associated with post-lung transplant mortality. The European respiratory journal\| PubMed ID: 31164432	2019
Lung cancer photothermal ablation by low-power near-infrared laser and topical injection of indocyanine green. Interactive cardiovascular and thoracic surgery\| PubMed ID: 31280301	2019
Lung Density Analysis Using Quantitative Chest CT for Early Prediction of Chronic Lung Allograft Dysfunction. Transplantation\| PubMed ID: 31343572	2019
A B cell-dependent pathway drives chronic lung allograft rejection after ischemia-reperfusion injury in mice. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 31365766	2019
The impact of first untreated subclinical minimal acute rejection on risk for chronic lung allograft dysfunction or death after lung transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 31397939	2020
Mesenchymal stromal cell therapy during ex vivo lung perfusion ameliorates ischemia-reperfusion injury in lung transplantation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 31474491	2019
Cricotracheal resection for adult subglottic stenosis: Factors predicting treatment failure. The Laryngoscope\| PubMed ID: 31498456	2020
Drug-resistant cytomegalovirus infection after lung transplantation: Incidence, characteristics, and clinical outcomes. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 31570289	2019
Bilateral Lobar Transplants Using One Donor for Two Small-Sized Recipients. The Annals of thoracic surgery\| PubMed ID: 31586617	2020
Long-term Outcomes of Lung Transplant With Ex Vivo Lung Perfusion. JAMA surgery\| PubMed ID: 31596484	2019
Normothermic ex vivo lung perfusion: Does the indication impact organ utilization and patient outcomes after transplantation? The Journal of thoracic and cardiovascular surgery\| PubMed ID: 31606173	2020
Prevention of viral transmission during lung transplantation with hepatitis C-viraemic donors: an open-label, single-centre, pilot trial. The Lancet. Respiratory medicine\| PubMed ID: 31606437	2020
Prognostic influence of tumor microenvironment after hypofractionated radiation and surgery for mesothelioma. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 31866087	2020
Incidence of Ipsilateral Side Recurrence After Open or Video-Assisted Thoracic Surgery Resection of Colorectal Lung Metastases. The Annals of thoracic surgery\| PubMed ID: 31953045	2020
Initial lung transplantation experience with uncontrolled donation after cardiac death in North America. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 31995660	2020
Granuloma in the explanted lungs: Infectious causes and impact on post-lung transplant mycobacterial infection. Transplant infectious disease : an official journal of the Transplantation Society\| PubMed ID: 32043708	2020
Potential therapeutic targets for lung repair during human lung perfusion. The European respiratory journal\| PubMed ID: 32060066	2020
Increased Arginase Expression and Decreased Nitric Oxide in Pig Donor Lungs after Normothermic Ex Vivo Lung Perfusion. Biomolecules\| PubMed ID: 32075026	2020
Late Onset Invasive Pulmonary Aspergillosis in Lung Transplant Recipients in the Setting of a Targeted Prophylaxis/Preemptive Antifungal Therapy Strategy. Transplantation\| PubMed ID: 32080158	2020
Lung transplantation for cystic fibrosis. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 32147452	2020
The Impact of Inadequate ("AX") Transbronchial Biopsies on Post-lung Transplant CLAD or Death. Transplantation\| PubMed ID: 32150039	2021
Extending cytomegalovirus prophylaxis in high-risk (D+/R-) lung transplant recipients from 6 to 9 months reduces cytomegalovirus disease: A retrospective study. Transplant infectious disease : an official journal of the Transplantation Society\| PubMed ID: 32170813	2020
An extracellular oxygen carrier during prolonged pulmonary preservation improves post-transplant lung function. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 32334946	2020
A model to assess acute and delayed lung toxicity of oxaliplatin during in vivo lung perfusion. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 32354628	2021
Short-course, direct-acting antivirals and ezetimibe to prevent HCV infection in recipients of organs from HCV-infected donors: a phase 3, single-centre, open-label study. The lancet. Gastroenterology & hepatology\| PubMed ID: 32389183	2020
Risk assessment of chronic lung allograft dysfunction phenotypes: Validation and proposed refinement of the 2019 International Society for Heart and Lung Transplantation classification syste... The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 32418864	2020
Bronchoalveolar bile acid and inflammatory markers to identify high-risk lung transplant recipients with reflux and microaspiration. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 32487471	2020
The case for routine screening for SARS-CoV-2 before surgery. Canadian journal of anaesthesia = Journal canadien d'anesthesie\| PubMed ID: 32495121	2020
Personalized Ventilation to Multiple Patients Using a Single Ventilator: Description and Proof of Concept. Critical care explorations\| PubMed ID: 32671348	2020
Deceased-donor lobar lung transplant: A successful strategy for small-sized recipients. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 32723591	2021
Retrospective study of the incidence and outcomes from lung cancer in solid organ transplant recipients. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 32738417	2020
Impact of donor time to cardiac arrest in lung donation after circulatory death. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 32747131	2021
Identifying host microRNAs in bronchoalveolar lavage samples from lung transplant recipients infected with Aspergillus. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 32771440	2020
International Society for Heart and Lung Transplantation consensus statement for the standardization of bronchoalveolar lavage in lung transplantation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 32773322	2020
Lung donation after medical assistance in dying at home. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 32803817	2021
Surgical Morbidity of Full-Thickness Chest Wall Resection for Breast Cancer: A Retrospective Study of a National Database. The Journal of surgical research\| PubMed ID: 32829000	2021
When to consider lung transplantation for COVID-19. The Lancet. Respiratory medicine\| PubMed ID: 32857989	2020
Cell-free DNA in human ex vivo lung perfusate as a potential biomarker to predict the risk of primary graft dysfunction in lung transplantation. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 32928548	2021
The impact of concordance with a lung cancer diagnosis pathway guideline on treatment access in patients with stage IV lung cancer. Journal of thoracic disease\| PubMed ID: 32944345	2020
Ex-vivo delivery of monoclonal antibody (Rituximab) to treat human donor lungs prior to transplantation. EBioMedicine\| PubMed ID: 32950000	2020
Strategies to prolong homeostasis of ex vivo perfused lungs. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 32958268	2021
Ex vivo lung perfusion for donor lung assessment and repair: a review of translational interspecies models. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 32996780	2020
Eosinophils in transbronchial biopsies: a predictor of chronic lung allograft dysfunction and reduced survival after lung transplantation - a retrospective single-center cohort study. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 33025592	2021
Effect of Driving Pressure Change During Extracorporeal Membrane Oxygenation in Adults With Acute Respiratory Distress Syndrome: A Randomized Crossover Physiologic Study. Critical care medicine\| PubMed ID: 33044283	2020
Rare indications for a lung transplant. A European Society of Thoracic Surgeons survey. Interactive cardiovascular and thoracic surgery\| PubMed ID: 33057713	2020
Veno-venous ECMO as a platform to evaluate lung lavage and surfactant replacement therapy in an animal model of severe ARDS. Intensive care medicine experimental\| PubMed ID: 33108583	2020
Transcriptomic investigation reveals donor-specific gene signatures in human lung transplants. The European respiratory journal\| PubMed ID: 33122335	2021
Ventilation parameters and early graft function in double lung transplantation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 33144029	2021
Donor ventilation parameters as predictors for length of mechanical ventilation after lung transplantation: Results of a prospective multicenter study. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 33246712	2021
Alpha-1 Antitrypsin for COVID-19 Treatment: Dual Role in Antiviral Infection and Anti-Inflammation. Frontiers in pharmacology\| PubMed ID: 33362565	2020
CYP51A polymorphisms of Aspergillus fumigatus in lung transplant recipients: Prevalence, correlation with phenotype, and impact on outcomes. Medical mycology\| PubMed ID: 33418565	2021
Surgery for malignant pleural mesothelioma after radiotherapy (SMART): final results from a single-centre, phase 2 trial. The Lancet. Oncology\| PubMed ID: 33450184	2021
Safety of continuous 12-hour delivery of antimicrobial doses of inhaled nitric oxide during ex vivo lung perfusion. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 33478833	2022
Successful lung transplantation from lungs procured 12 hours after withdrawal of life-sustaining therapy: Changing the paradigm of controlled DCD donors? The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 33602628	2021
Thymoma pathology and myasthenia gravis outcomes. Muscle & nerve\| PubMed ID: 33675078	2021
Using nutrient-rich solutions and adding multiple cytoprotective agents as new strategies to develop lung preservation solutions. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 33688744	2021
Solid phase microextraction chemical biopsy tool for monitoring of doxorubicin residue during in vivo lung chemo-perfusion. Journal of pharmaceutical analysis\| PubMed ID: 33717610	2021
A call to routinely test lower respiratory tract samples for SARS-CoV-2 in lung donors. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 33756058	2021
Prediction of donor related lung injury in clinical lung transplantation using a validated ex vivo lung perfusion inflammation score. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 33781664	2021
Prognostic Significance of Pulmonary Multifocal Neuroendocrine Proliferation With Typical Carcinoid. The Annals of thoracic surgery\| PubMed ID: 33831394	2022
Use of metabolomics to identify strategies to improve and prolong ex vivo lung perfusion for lung transplants. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 33849769	2021
Predicting donor lung acceptance for transplant during ex vivo lung perfusion: The EX vivo lung PerfusIon pREdiction (EXPIRE). American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 33872459	2021
Interleukin-6 receptor blockade in patients with COVID-19: placing clinical trials into context. The Lancet. Respiratory medicine\| PubMed ID: 33930329	2021
Pushing the Envelope for Donor Lungs. Seminars in respiratory and critical care medicine\| PubMed ID: 34030199	2021
Telerehabilitation for Lung Transplant Candidates and Recipients During the COVID-19 Pandemic: Program Evaluation. JMIR mHealth and uHealth\| PubMed ID: 34048354	2021
Long-term outcomes of sensitized lung transplant recipients after peri-operative desensitization. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 34058795	2021
Achieving Safe Liberation During Weaning From VV-ECMO in Patients With Severe ARDS: The Role of Tidal Volume and Inspiratory Effort. Chest\| PubMed ID: 34166645	2021
Diffusing capacity of the lung for carbon monoxide: association with long-term outcomes after lung transplantation in a 20-year longitudinal study. The European respiratory journal\| PubMed ID: 34172463	2022
The accuracy of forced vital capacity for diagnosing restrictive allograft syndrome and mixed phenotype of chronic lung allograft dysfunction. The European respiratory journal\| PubMed ID: 34172465	2021
Bronchoalveolar lavage cytokine-based risk stratification of minimal acute rejection in clinically stable lung transplant recipients. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 34215500	2021
Surfactant therapy in lung transplantation: A systematic review and meta-analysis. Transplantation reviews (Orlando, Fla.)\| PubMed ID: 34224988	2021
A simplified strategy for donor-recipient size-matching in lung transplant for interstitial lung disease. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 34301464	2021
Maintaining technical proficiency in senior surgical fellows during the COVID-19 pandemic through virtual teaching. JTCVS open\| PubMed ID: 34308384	2021
Tracheobronchoplasty followed by bilateral lung transplantation for Mounier-Kuhn syndrome. JTCVS techniques\| PubMed ID: 34317944	2020
delivery of regulatory T-cells for control of alloimmune priming in the donor lung. The European respiratory journal\| PubMed ID: 34475226	2022
Static lung storage at 10°C maintains mitochondrial health and preserves donor organ function. Science translational medicine\| PubMed ID: 34524862	2021
Recipient bone marrow-derived IL-17 receptor A-positive cells drive allograft fibrosis in a mouse intrapulmonary tracheal transplantation model. Transplant immunology\| PubMed ID: 34547417	2021
A novel pre-clinical strategy to deliver antimicrobial doses of inhaled nitric oxide. PloS one\| PubMed ID: 34644318	2021
Engineered mesenchymal stromal cell therapy during human lung lung perfusion is compromised by acidic lung microenvironment. Molecular therapy. Methods & clinical development\| PubMed ID: 34703841	2021
Significance of phenotype change after chronic lung allograft dysfunction onset. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 34748217	2021
Connective-Tissue Growth Factor Contributes to TGF-β1-induced Lung Fibrosis. American journal of respiratory cell and molecular biology\| PubMed ID: 34797990	2022
Ex vivo treatment of cytomegalovirus in human donor lungs using a novel chemokine-based immunotoxin. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 34802874	2022
Transcripts associated with chronic lung allograft dysfunction in transbronchial biopsies of lung transplants. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 34850543	2022
Postoperative Management of Lung Transplant Recipients in the Intensive Care Unit. Anesthesiology\| PubMed ID: 34910811	2022
lung perfusion. Journal of thoracic disease\| PubMed ID: 34992839	2021
Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles. Science immunology\| PubMed ID: 34995099	2022
Outcomes of lung transplantation from organ donation after medical assistance in dying: First North American experience. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 35108446	2022
Ex vivo enzymatic treatment converts blood type A donor lungs into universal blood type lungs. Science translational medicine\| PubMed ID: 35171649	2022
Expression of cystic fibrosis lung disease modifier genes in human airway models. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society\| PubMed ID: 35190293	2022
Importance of tumor size in resectable stage III-N2 non-small cell lung cancer. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 35331553	2022
Lung transplantation for acute respiratory distress syndrome. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 35379475	2023
Near-infrared fluorescence imaging during ex vivo lung perfusion: Noninvasive real-time evaluation of regional lung perfusion and edema. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 35382935	2022
Statement regarding events in Ukraine from Shaf Keshavjee, MD, 102nd President, The American Association for Thoracic Surgery. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 35382937	2022
Survival After Lung Transplantation for Chronic Hypersensitivity Pneumonitis: Results From a Large International Cohort Study. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 35431638	2022
Altered purine metabolism at reperfusion affects clinical outcome in lung transplantation. Thorax\| PubMed ID: 35450941	2023
Endobronchial ultrasound-guided bipolar radiofrequency ablation for lung cancer: A first-in-human clinical trial. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 35459539	2022
Outcomes of lung transplantation at a Canadian center using donors declined in the United States. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 35461711	2022
Interferon-stimulated and metallothionein-expressing macrophages are associated with acute and chronic allograft dysfunction after lung transplantation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 35691795	2022
Successful sequential transplantation of 2 single lungs from the same donor into 2 different recipients-use of standard cold preservation and 10 °C preservation. JTCVS techniques\| PubMed ID: 35711178	2022
A Biomarker-Based Approach for the Determination of Sample Adequacy During Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: A Proof of Concept Study. Chest\| PubMed ID: 35841933	2023
A practical and immediately available size-match strategy improves short and long term outcomes in lung transplantation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 35842354	2022
Statin Use May Be Associated With a Lower Risk of Invasive Aspergillosis in Lung Transplant Recipients. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 35900334	2023
Successful 3-day lung preservation using a cyclic normothermic ex vivo lung perfusion strategy. EBioMedicine\| PubMed ID: 35952495	2022
Successful use of a hepatitis C viremic donor in pediatric bilateral lobar lung transplantation. JTCVS techniques\| PubMed ID: 35967204	2022
Human organ repair centers: Fact or fiction? JTCVS open\| PubMed ID: 36003866	2020
Utility of bile acids in large airway bronchial wash versus bronchoalveolar lavage as biomarkers of microaspiration in lung transplant recipients: a retrospective cohort study. Respiratory research\| PubMed ID: 36028826	2022
Strategies for lung- and diaphragm-protective ventilation in acute hypoxemic respiratory failure: a physiological trial. Critical care (London, England)\| PubMed ID: 36038890	2022
A biomarker assay to risk-stratify patients with symptoms of respiratory tract infection. The European respiratory journal\| PubMed ID: 36104292	2022
The molecular features of chronic lung allograft dysfunction in lung transplant airway mucosa. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 36163162	2022
The Association Between Extravascular Lung Water and Critical Care Outcomes Following Bilateral Lung Transplantation. Transplantation direct\| PubMed ID: 36176725	2022
Reflux Surgery in Lung Transplantation: A Multicenter Retrospective Study. The Annals of thoracic surgery\| PubMed ID: 36216086	2023
Outcomes of lung transplantation from donors with a history of substance abuse. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 36216597	2023
Evaluation of 10°C as the optimal storage temperature for aspiration-injured donor lungs in a large animal transplant model. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 36216693	2022
Thrombopoietin participates in platelet activation in COVID-19 patients. EBioMedicine\| PubMed ID: 36242922	2022
Determining the impact of ex-vivo lung perfusion on hospital costs for lung transplantation: A retrospective cohort study. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 36411188	2023
L-alanyl-L-glutamine modified perfusate improves human lung cell functions and extend porcine ex vivo lung perfusion. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 36411189	2023
Influence of anterior tumor location on survival after resection of lung cancer invading the thoracic inlet (Pancoast tumors). The Journal of thoracic and cardiovascular surgery\| PubMed ID: 36481062	2023
Testing the delivery of human organ transportation with drones in the real world. Science robotics\| PubMed ID: 36542685	2022
102nd American Association for Thoracic Surgery Presidential Address: What's next? The Journal of thoracic and cardiovascular surgery\| PubMed ID: 36549984	2023
Low-Flow Inflation Pressure-Time Curve to Identify Airway Opening Pressure in a Patient Receiving Venovenous Extracorporeal Membrane Oxygenation. American journal of respiratory and critical care medicine\| PubMed ID: 36693031	2023
Donor and recipient human leukocyte antigen-G polymorphisms modulate the risk of adverse immunologic events following lung transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 36695689	2023
Triaging donor lungs based on a microaspiration signature that predicts adverse recipient outcome. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 36710092	2023
Donor Batf3 inhibits murine lung allograft rejection and airway fibrosis. Mucosal immunology\| PubMed ID: 36842540	2023
Lung Transplantation for Primary Ciliary Dyskinesia and Kartagener Syndrome: A Multicenter Study. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 36865666	2023
Immunohistochemical Analysis of Lymphocyte Populations in Acute Skin Rejection: The University Health Network Addition to the Banff Classification. Plastic and reconstructive surgery. Global open\| PubMed ID: 36875922	2023
Vascular-Parenchymal Cross-Talk Promotes Lung Fibrosis through BMPR2 Signaling. American journal of respiratory and critical care medicine\| PubMed ID: 36917778	2023
Pulmonary epithelial markers in phenotypes of chronic lung allograft dysfunction. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 36963446	2023
Alpha-1-antitrypsin safely promotes rapid recovery of pigs after lung transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 37004914	2023
Evaluating the Impact of Ex Vivo Lung Perfusion on Organ Transplantation: A Retrospective Cohort Study. Annals of surgery\| PubMed ID: 37073734	2023
Outcomes after flow cytometry crossmatch-positive lung transplants managed with perioperative desensitization. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 37172694	2023
Outcomes of patients with respiratory failure declined for extracorporeal membrane oxygenation: a prospective observational study. Canadian journal of anaesthesia = Journal canadien d'anesthesie\| PubMed ID: 37280459	2023
Defining a natural killer cell-enriched molecular rejection-like state in lung transplant transbronchial biopsies. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 37295720	2023
Intra-subject variability in oscillometry correlates with acute rejection and CLAD post-lung transplant. Frontiers in medicine\| PubMed ID: 37305133	2023
Immunomodulation of the donor lung with CRISPR-mediated activation of IL-10 expression. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 37315746	2023
A Novel Tissue Preservation and Transport Solution as a Substitute for Formalin. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 37321542	2023
Mesenchymal Stromal Cell Therapy in Lung Transplantation. Bioengineering (Basel, Switzerland)\| PubMed ID: 37370659	2023
Time to extubation for lung transplant recipients represents a pragmatic end-point to guide the development of prognostic tests. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 37406839	2023
Incidence of post-transplant cytomegalovirus viremia in patients receiving lungs after ex vivo lung perfusion. JTCVS open\| PubMed ID: 37425481	2023
Identification of regional variation in gene expression and inflammatory proteins in donor lung tissue and ex vivo lung perfusate. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 37482240	2023
Extending the age criteria of lung transplant donors to 70+ years old does not significantly affect recipient survival. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 37541572	2023
Pregnancy and pulmonary hypertension in the pre-lung transplant patient: Successfully saving two lives with extracorporeal lung support. JTCVS techniques\| PubMed ID: 37555024	2023
A machine-learning approach to human ex vivo lung perfusion predicts transplantation outcomes and promotes organ utilization. Nature communications\| PubMed ID: 37558674	2023
Center variability in the prognostic value of a cumulative acute cellular rejection "A-score" for long-term lung transplant outcomes. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 37625646	2023
De Novo Design and Development of a Nutrient-Rich Perfusate for Ex Vivo Lung Perfusion with Cell Culture Models. International journal of molecular sciences\| PubMed ID: 37685927	2023
Necroptosis in Organ Transplantation: Mechanisms and Potential Therapeutic Targets. Cells\| PubMed ID: 37759518	2023
THE IMPACT OF INTRA-OPERATIVE THERAPEUTIC PLASMA EXCHANGE ON BLEEDING IN LUNG TRANSPLANTATION. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 37813131	2023
Oesophageal stasis is a risk factor for chronic lung allograft dysfunction and allograft failure in lung transplant recipients. ERJ open research\| PubMed ID: 37817870	2023
Acellular ex vivo lung perfusate silences pro-inflammatory signaling in human lung endothelial and epithelial cells. Journal of translational medicine\| PubMed ID: 37845763	2023
Donor IL-17 receptor A regulates LPS-potentiated acute and chronic murine lung allograft rejection. JCI insight\| PubMed ID: 37937643	2023