Thomas Chuen Lam

Centre for Myopia Research, The Hong Kong Polytechnic University

Affiliated withThe Hong Kong Polytechnic University Centre for Eye and Vision Research (CEVR)

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 2	2023
Publication title	2025

Other Publications

Article	Year
Cyclic Adenosine Monophosphate Activates Retinal Apolipoprotein A1 Expression and Inhibits Myopic Eye Growth. Investigative ophthalmology & visual science\| PubMed ID: 26720467	2015
Post-translational modifications and their applications in eye research (Review). Molecular medicine reports\| PubMed ID: 28487982	2017
New Insight of Common Regulatory Pathways in Human Trabecular Meshwork Cells in Response to Dexamethasone and Prednisolone Using an Integrated Quantitative Proteomics: SWATH and MRM-HR Mass ... Journal of proteome research\| PubMed ID: 28920441	2017
Isotope-coded protein label based quantitative proteomic analysis reveals significant up-regulation of apolipoprotein A1 and ovotransferrin in the myopic chick vitreous. Scientific reports\| PubMed ID: 28978931	2017
Integrated SWATH-based and targeted-based proteomics provide insights into the retinal emmetropization process in guinea pig. Journal of proteomics\| PubMed ID: 29572162	2018
The Interactions Between Bright Light and Competing Defocus During Emmetropization in Chicks. Investigative ophthalmology & visual science\| PubMed ID: 30025112	2018
The Role of the RhoA/ROCK Signaling Pathway in Mechanical Strain-Induced Scleral Myofibroblast Differentiation. Investigative ophthalmology & visual science\| PubMed ID: 30029249	2018
Data on differentially expressed proteins in retinal emmetropization process in guinea pig using integrated SWATH-based and targeted-based proteomics. Data in brief\| PubMed ID: 30505911	2018
Data on corneal proteome and differentially expressed corneal proteins in highly myopic chicks using a data independent quantification approach. Data in brief\| PubMed ID: 31667243	2019
Alteration of retinal metabolism and oxidative stress may implicate myopic eye growth: Evidence from discovery and targeted proteomics in an animal model. Journal of proteomics\| PubMed ID: 32061809	2020
Data on assessment of safety and tear proteome change in response to orthokeratology lens - Insight from integrating clinical data and next generation proteomics. Data in brief\| PubMed ID: 32071970	2020
Data on protein changes of chick vitreous during normal eye growth using data-independent acquisition (SWATH-MS). Data in brief\| PubMed ID: 32373688	2020
Data on differentially expressed proteins in rock inhibitor-treated human trabecular meshwork cells using SWATH-based proteomics. Data in brief\| PubMed ID: 32613038	2020
Combined retinal proteome datasets in response to atropine treatment using iTRAQ and SWATH-MS based proteomics approaches in guinea pig myopia model. Data in brief\| PubMed ID: 33304948	2020
High-pH reversed-phase fractionated neural retina proteome of normal growing C57BL/6 mouse. Scientific data\| PubMed ID: 33500412	2021
Corneal proteome and differentially expressed corneal proteins in highly myopic chicks using a label-free SWATH-MS quantification approach. Scientific reports\| PubMed ID: 33750851	2021
Critical role of mass spectrometry proteomics in tear biomarker discovery for multifactorial ocular diseases (Review). International journal of molecular medicine\| PubMed ID: 33760148	2021
SWATH Based Quantitative Proteomics Reveals Significant Lipid Metabolism in Early Myopic Guinea Pig Retina. International journal of molecular sciences\| PubMed ID: 33946922	2021
The Effect of Low-Dose Atropine on Alpha Ganglion Cell Signaling in the Mouse Retina. Frontiers in cellular neuroscience\| PubMed ID: 34025362	2021
Human tear proteome dataset in response to daily wear of water gradient contact lens using SWATH-MS approach. Data in brief\| PubMed ID: 34095372	2021
Thrombospondin-1 mediates Rho-kinase inhibitor-induced increase in outflow-facility. Journal of cellular physiology\| PubMed ID: 34180057	2021
Alteration of EIF2 Signaling, Glycolysis, and Dopamine Secretion in Form-Deprived Myopia in Response to 1% Atropine Treatment: Evidence From Interactive iTRAQ-MS and SWATH-MS Proteomics Usin... Frontiers in pharmacology\| PubMed ID: 35153787	2022
Transcriptional profiling of the chick retina identifies down-regulation of and genes during early lens-induced myopia. Molecular omics\| PubMed ID: 35420081	2022
Retinal Proteomic Analysis in a Mouse Model of Endotoxin-Induced Uveitis Using Data-Independent Acquisition-Based Mass Spectrometry. International journal of molecular sciences\| PubMed ID: 35742911	2022
Mechanistic Effects of Baicalein on Aqueous Humor Drainage and Intraocular Pressure. International journal of molecular sciences\| PubMed ID: 35806375	2022
Proteomic Profiling Revealed Mitochondrial Dysfunction in Photoreceptor Cells under Hyperglycemia. International journal of molecular sciences\| PubMed ID: 36362154	2022
Additive effects of narrowband light and optical defocus on chick eye growth and refraction. Eye and vision (London, England)\| PubMed ID: 37004128	2023
Differential Responses of Retinal Neurons and Glia Revealed via Proteomic Analysis on Primary and Secondary Retinal Ganglion Cell Degeneration. International journal of molecular sciences\| PubMed ID: 37569482	2023
A review of using Traditional Chinese Medicine in the management of glaucoma and cataract. Clinical & experimental optometry\| PubMed ID: 37879342	2023
Neuropathic Corneal Pain: Tear Proteomic and Neuromediator Profiles, Imaging Features, and Clinical Manifestations. American journal of ophthalmology\| PubMed ID: 38521157	2024
Ocular surface parameters repeatability and agreement -A comparison between Keratograph 5M and IDRA. Contact lens & anterior eye : the journal of the British Contact Lens Association\| PubMed ID: 39097427	2024
Metabolomics studies in common multifactorial eye disorders: a review of biomarker discovery for age-related macular degeneration, glaucoma, diabetic retinopathy and myopia. Frontiers in molecular biosciences\| PubMed ID: 39193222	2024
Interaction of retinal electrophysiology and novel orthokeratology lens use on myopia control efficacy in children. The British journal of ophthalmology\| PubMed ID: 39332846	2025
Deep Spectral Library of Mice Retina for Myopia Research: Proteomics Dataset generated by SWATH and DIA-NN. Scientific data\| PubMed ID: 39389962	2024
Identification of Potential Growth-Related Proteins in Chick Vitreous during Emmetropization Using SWATH-MS and Targeted-Based Proteomics (MRMHR). International journal of molecular sciences\| PubMed ID: 39408973	2024
Cone-rod homeobox transcriptionally activates TCF7 to promote the proliferation of retinal pigment epithelial and retinoblastoma cells . International journal of ophthalmology\| PubMed ID: 39559312	2024
Thrombospondin 1 Mediates Autophagy Upon Inhibition of the Rho-Associated Protein Kinase Inhibitor. Cells\| PubMed ID: 39594655	2024
Validation and repeatability assessment of the Chinese version of the Ocular Surface Disease Index (OSDI), 5-item dry eye (DEQ-5), and contact lens dry eye questionnaire-8 (CLDEQ-8) question... Contact lens & anterior eye : the journal of the British Contact Lens Association\| PubMed ID: 39694733	2025
Neuropathic corneal pain following refractive surgery: risk factors, clinical manifestations, imaging and proteomic characteristics. The British journal of ophthalmology\| PubMed ID: 39880672	2025
Comparative analysis of ocular biometrics using spectral domain optical coherence tomography with Purkinje image and optic nerve head alignments in mice. European journal of medical research\| PubMed ID: 39901220	2025
Upregulations of SNAT2 and GLS-1 Are Key Osmoregulatory Responses of Human Corneal Epithelial Cells to Hyperosmotic Stress. Journal of proteome research\| PubMed ID: 40360154	2025
A Comprehensive Proteome of Human Corneal Epithelial Cells Constructed by Cross-platform DIA-Mass Spectrometry. Scientific data\| PubMed ID: 40410165	2025
Fenofibrate ameliorates ocular surface inflammation in diabetic keratopathy. The ocular surface\| PubMed ID: 40451569	2025
Bidirectional Phosphorylation Changes in Opsins Associated With Early Myopia and Hyperopia Signal Regulation by Phosphoproteomics. Investigative ophthalmology & visual science\| PubMed ID: 40736176	2025
Comprehensive characterization of human aqueous humor proteomes from primary open-angle glaucoma using data-independent acquisition dataset on a TimsTOF pro mass spectrometer. Data in brief\| PubMed ID: 40756422	2025