Larry A. Walker

National Center for Natural Products Research, University of Mississippi

Affiliated withUniversity of Mississippi

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 117	2012

Other Publications

Article	Year
Time-resolved spectroscopic studies of B(12) coenzymes: a comparison of the primary photolysis mechanism in methyl-, ethyl-, n-propyl-, and 5'-deoxyadenosylcobalamin. Journal of the American Chemical Society\| PubMed ID: 11792214	2002
Natural products inhibiting Candida albicans secreted aspartic proteases from Tovomita krukovii. Planta medica\| PubMed ID: 11842327	2002
Biologically active secondary metabolites from Ginkgo biloba. Journal of agricultural and food chemistry\| PubMed ID: 12009978	2002
Antifungal activity of eupolauridine and its action on DNA topoisomerases. Antimicrobial agents and chemotherapy\| PubMed ID: 12019091	2002
New sesquiterpenoids from the root of Guatteria multivenia. Journal of natural products\| PubMed ID: 12088427	2002
Natural products inhibiting Candida albicans secreted aspartic proteases from Lycopodium cernuum. Journal of natural products\| PubMed ID: 12141856	2002
Characterization of Mycotypha metabolites found to be inhibitors of cell adhesion molecules. The Journal of antibiotics\| PubMed ID: 12195965	2002
Fatty acid synthase inhibitors from plants: isolation, structure elucidation, and SAR studies. Journal of natural products\| PubMed ID: 12502337	2002
Flavanone glycosides from Miconia trailii. Journal of natural products\| PubMed ID: 12542342	2003
Cytotoxic sesquiterpene lactones from Centaurothamnus maximus and Vicoa pentanema. Phytotherapy research : PTR\| PubMed ID: 12601682	2003
Genipatriol, a new cycloartane triterpene from Genipa spruceana. Journal of natural products\| PubMed ID: 12662099	2003
Phenolic compounds from Nymphaea odorata. Journal of natural products\| PubMed ID: 12713413	2003
Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae. The Journal of biological chemistry\| PubMed ID: 12824174	2003
A new triterpene from Leandra chaetodon. Planta medica\| PubMed ID: 12865988	2003
Antiparasitic alkaloids from Psychotria klugii. Journal of natural products\| PubMed ID: 12880315	2003
Acetylenic acids inhibiting azole-resistant Candida albicans from Pentagonia gigantifolia. Journal of natural products\| PubMed ID: 12932143	2003
Cytotoxic and antioxidant activities of alkylated benzoquinones from Maesa lanceolata. Phytotherapy research : PTR\| PubMed ID: 13680818	2003
Reversal of fluconazole resistance in multidrug efflux-resistant fungi by the Dysidea arenaria sponge sterol 9alpha,11alpha-epoxycholest-7-ene-3beta,5alpha,6alpha,19-tetrol 6-acetate. Journal of natural products\| PubMed ID: 14695809	2003
Spectrophotometric determination of de novo hemozoin/beta-hematin formation in an in vitro assay. Analytical biochemistry\| PubMed ID: 14715288	2004
Transport of parthenolide across human intestinal cells (Caco-2). Planta medica\| PubMed ID: 14735438	2003
Circular dichroic properties of flavan-3,4-diols. Journal of natural products\| PubMed ID: 14987054	2004
Antimalarial and antileishmanial activities of aroyl-pyrrolyl-hydroxyamides, a new class of histone deacetylase inhibitors. Antimicrobial agents and chemotherapy\| PubMed ID: 15047563	2004
Synthesis and anticancer activities of fatty acid analogs of podophyllotoxin. Lipids\| PubMed ID: 15134144	2004
A new antimalarial quassinoid from Simaba orinocensis. Journal of natural products\| PubMed ID: 15165136	2004
Antifungal cyclopentenediones from Piper coruscans. Journal of the American Chemical Society\| PubMed ID: 15174849	2004
Piperazine-linked bisbenzamidines: a novel class of antileishmanial agents. European journal of medicinal chemistry\| PubMed ID: 15183913	2004
An alpha-proteobacterial type malate dehydrogenase may complement LDH function in Plasmodium falciparum. Cloning and biochemical characterization of the enzyme. European journal of biochemistry / FEBS\| PubMed ID: 15317584	2004
Antimicrobial and antileishmanial activities of hypocrellins A and B. Antimicrobial agents and chemotherapy\| PubMed ID: 15504880	2004
Synthesis, spectroscopic, and biological studies of novel estolides derived from anticancer active 4-O-podophyllotoxinyl 12-hydroxyl-octadec-Z-9-enoate. Lipids\| PubMed ID: 15588023	2004
Targeting the hemozoin synthesis pathway for new antimalarial drug discovery: technologies for in vitro beta-hematin formation assay. Combinatorial chemistry & high throughput screening\| PubMed ID: 15720198	2005
Natural products and antifungal drug discovery. Methods in molecular medicine\| PubMed ID: 15888937	2005
Identification of bis-quindolines as new antiinfective agents. Bioorganic & medicinal chemistry\| PubMed ID: 15911310	2005
Anticancer activity and possible mode of action of 4-O-podophyllotoxinyl 12-hydroxyl-octadec-Z-9-enoate. Lipids\| PubMed ID: 15957257	2005
Synthesis and in vitro cytotoxic activity of N-, F-, and S-ether derivatives of podophyllotoxin fatty acid adducts. Lipids\| PubMed ID: 16028720	2005
Phenolic glycosides from Potalia amara. Planta medica\| PubMed ID: 16254836	2005
Antimycotic drug discovery in the age of genomics. American journal of pharmacogenomics : genomics-related research in drug development and clinical practice\| PubMed ID: 16336002	2005
8-Aminoquinolines: future role as antiprotozoal drugs. Current opinion in infectious diseases\| PubMed ID: 17075340	2006
Growth, drug susceptibility, and gene expression profiling of Plasmodium falciparum cultured in medium supplemented with human serum or lipid-rich bovine serum albumin [corrected]. Journal of biomolecular screening\| PubMed ID: 18087074	2007
Role of heme in the antifungal activity of the azaoxoaporphine alkaloid sampangine. Eukaryotic cell\| PubMed ID: 18156292	2008
Transport of Schisandra chinensis extract and its biologically-active constituents across Caco-2 cell monolayers - an in-vitro model of intestinal transport. The Journal of pharmacy and pharmacology\| PubMed ID: 18284817	2008
Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichlorophenoxy]quinoline succinate. Antimicrobial agents and chemotherapy\| PubMed ID: 18378716	2008
Antioxidant constituents of Nymphaea caerulea flowers. Phytochemistry\| PubMed ID: 18534639	2008
In vitro metabolic stability and intestinal transport of P57AS3 (P57) from Hoodia gordonii and its interaction with drug metabolizing enzymes. Planta medica\| PubMed ID: 18612942	2008
New labdane diterpenes from Leonurus cardiaca. Planta medica\| PubMed ID: 18666048	2008
Indolizidine, antiinfective and antiparasitic compounds from Prosopis glandulosa var. glandulosa. Journal of natural products\| PubMed ID: 19105653	2009
Alkaloids and saponins as cytochrome P450 inhibitors from blue cohosh (Caulophyllum thalictroides) in an in vitro assay. Planta medica\| PubMed ID: 19137500	2009
Analysis of quaternary structure of a [LDH-like] malate dehydrogenase of Plasmodium falciparum with oligomeric mutants. Molecular and cellular biochemistry\| PubMed ID: 19184366	2009
Bioactive (+)-manzamine A and (+)-8-hydroxymanzamine A tertiary bases and salts from Acanthostrongylophora ingens and their preparations. Natural product communications\| PubMed ID: 19370920	2009
Cytochrome P(450)-dependent toxic effects of primaquine on human erythrocytes. Toxicology and applied pharmacology\| PubMed ID: 19616568	2009
Antimicrobial, antiparasitic and cytotoxic spermine alkaloids from Albizia schimperiana. Natural product communications\| PubMed ID: 19634324	2009
Characterization of in vitro pharmacokinetic properties of hoodigogenin A from Hoodia gordonii. Planta medica\| PubMed ID: 19639535	2010
Structure and function of Plasmodium falciparum malate dehydrogenase: role of critical amino acids in co-substrate binding pocket. Biochimie\| PubMed ID: 19772885	2009
Cytochrome P450-dependent toxicity of dapsone in human erythrocytes. Journal of applied toxicology : JAT\| PubMed ID: 19998329	2010
Selective inhibition of human leukemia cell growth and induction of cell cycle arrest and apoptosis by pseudolaric acid B. Journal of cancer research and clinical oncology\| PubMed ID: 20140742	2010
Bioavailability, pharmacokinetics, and tissue distribution of the oxypregnane steroidal glycoside P57AS3 (P57) from Hoodia gordonii in mouse model. Planta medica\| PubMed ID: 20414860	2010
How physicians should evaluate dietary supplements. The American journal of medicine\| PubMed ID: 20493463	2010
Antimicrobial and antiparasitic abietane diterpenoids from the roots of Clerodendrum eriophyllum. Natural product communications\| PubMed ID: 20614808	2010
Analysis of primaquine and its metabolite carboxyprimaquine in biological samples: enantiomeric separation, method validation and quantification. Biomedical chromatography : BMC\| PubMed ID: 21058417	2011
Identification of 3-phenylaminoquinolinium and 3-phenylaminopyridinium salts as new agents against opportunistic fungal pathogens. Bioorganic & medicinal chemistry\| PubMed ID: 21130660	2011
Benzothieno[3,2-b]quinolinium and 3-(phenylthio)quinolinium compounds: Synthesis and evaluation against opportunistic fungal pathogens. Bioorganic & medicinal chemistry\| PubMed ID: 21134759	2011
Methemoglobinemia caused by 8-aminoquinoline drugs: DFT calculations suggest an analogy to H4B's role in nitric oxide synthase. Journal of the American Chemical Society\| PubMed ID: 21244096	2011
Oxidized low-density lipoprotein and tissue factor are involved in monocrotaline/lipopolysaccharide-induced hepatotoxicity. Archives of toxicology\| PubMed ID: 21279329	2011
The marine sponge-derived polyketide endoperoxide plakortide F acid mediates its antifungal activity by interfering with calcium homeostasis. Antimicrobial agents and chemotherapy\| PubMed ID: 21300833	2011
Silencing of tissue factor by antisense deoxyoligonucleotide prevents monocrotaline/LPS renal injury in mice. Archives of toxicology\| PubMed ID: 21327618	2011
Optimization of 3-(phenylthio)quinolinium compounds against opportunistic fungal pathogens. European journal of medicinal chemistry\| PubMed ID: 21402432	2011
Dietary supplements: safety issues and quality control. Archives of internal medicine\| PubMed ID: 21403052	2011
Î´-Carbolines and their ring-opened analogs: synthesis and evaluation against fungal and bacterial opportunistic pathogens. European journal of medicinal chemistry\| PubMed ID: 21459492	2011
Tissue factor dependent liver injury causes release of retinoid receptors (RXR-Î± and RAR-Î±) as lipid droplets. Biochemical and biophysical research communications\| PubMed ID: 21658367	2011
Potential utility of natural products as regulators of breast cancer-associated aromatase promoters. Reproductive biology and endocrinology : RB&E\| PubMed ID: 21693041	2011
DFT study on the radical anions formed by primaquine and its derivatives. Chemical research in toxicology\| PubMed ID: 21699254	2011
Epigenetic events associated with breast cancer and their prevention by dietary components targeting the epigenome. Chemical research in toxicology\| PubMed ID: 21992498	2012
Antiparasitic and antimicrobial isoflavanquinones from Abrus schimperi. Natural product communications\| PubMed ID: 22224279	2011
Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs. Bioorganic & medicinal chemistry letters\| PubMed ID: 22264472	2012
Understanding the mechanisms for metabolism-linked hemolytic toxicity of primaquine against glucose 6-phosphate dehydrogenase deficient human erythrocytes: evaluation of eryptotic pathway. Toxicology\| PubMed ID: 22330256	2012
Tissue factor antisense deoxyoligonucleotide prevents monocrotaline/LPS hepatotoxicity in mice. Journal of applied toxicology : JAT\| PubMed ID: 22407844	2012
CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine. Malaria journal\| PubMed ID: 22856549	2012
Pentacyclic ingamine alkaloids, a new antiplasmodial pharmacophore from the marine sponge Petrosid Ng5 Sp5. Planta medica\| PubMed ID: 22903383	2012
Antiparasitic and anticancer carvotacetone derivatives of Sphaeranthus bullatus. Natural product communications\| PubMed ID: 23074885	2012