enhanced-communication-of-tumor-margins-using-3d-scanning-and-mapping

Enhanced Communication of Tumor Margins Using 3D Scanning and Mapping

After oncologic resection of malignant tumors, specimens are sent to pathology for processing to determine the surgical margin status. These results are ...

Vanderbilt University Medical Center

Numerous challenges exist in determining surgical margin status. Communication between surgeons and pathologists is crucial for specimen orientation and accurate margin assessment.

The computer-aided design margin: Ex vivo 3D specimen mapping to improve communication between surgeons and pathologists.

We have implemented a novel intraoperative communication system for head and neck surgical pathology using 3D scanning technology and computer-aided design (CAD) software. Here, we highlight our CAD margin protocol, in which we 3D scan head and neck oncologic surgical specimens and map frozen section results. This enhances the communication of margin status between surgeons and pathologists and delivers visual anatomic guidance for re-resection when needed. Laryngoscope, 133:1914-1918, 2023.

Enhanced Intraoperative Communication of Tumor Margins Using 3D Scanning and Mapping: The Computer-Aided Design Margin.

Structured light three-dimensional (3D) scanning is a ubiquitous mainstay of object inspection and quality control in industrial manufacturing, and has recently been integrated into various medical disciplines. Photorealistic 3D scans can readily be acquired from fresh or formalin-fixed tissue and have potential for use within anatomic pathology (AP) in a variety of scenarios, ranging from direct clinical care to documentation and education. Methods for scanning and post-processing of fresh surgical specimens rely on relatively low-cost and technically simple procedures. Here, we demonstrate potential use of 3D scanning in surgical pathology in the form of a mixed media pathology report with a novel post-scan virtual inking and marking technique to precisely demarcate areas of tissue sectioning and details of final tumor and margin status. We display a sample mixed-media pathology report (3D specimen map) which integrates 3D and conventional pathology reporting methods. Finally, we describe the potential utility of 3D specimen modeling in both didactic and experiential teaching of gross pathology lab procedures.

Ex vivo 3D scanning and specimen mapping in anatomic pathology.

Recent translational scientific efforts in subglottic stenosis (SGS) support a disease model where epithelial alterations facilitate microbiome displacement, dysregulated immune activation, and localized fibrosis. Yet despite recent advances, the genetic basis of SGS remains poorly understood. We sought to identify candidate risk genes associated with an SGS phenotype, investigate their biological function, and identify the cell types enriched for their expression.

Mapping Genetic Susceptibility to Stenosis in the Proximal Airway.

Given the complex three-dimensional (3D) anatomy of head and neck cancer specimens, head and neck surgeons often have difficulty relocating the site of an initial positive margin to perform re-resection. This cadaveric study aimed to determine the feasibility and accuracy of augmented reality surgery to guide head and neck cancer re-resections.

Augmented-Reality Surgery to Guide Head and Neck Cancer Re-resection: A Feasibility and Accuracy Study.

ASO Visual Abstract: Augmented Reality Surgery to Guide Head and Neck Cancer Re-resection: A Feasibility and Accuracy Study.

Virtual 3D specimen mapping of oncologic surgical specimens provides a visual record of the specimen and margin sampling sites which can be utilized in a variety of cancer care settings. Our objective was to perform a retrospective review of head and neck surgical oncology cases where the specimen was mapped post-operatively and to evaluate the utility of these 3D specimen maps amongst the multidisciplinary cancer care team.

Article	Year
The computer-aided design margin: Ex vivo 3D specimen mapping to improve communication between surgeons and pathologists. Head & neck\| PubMed ID: 36156327	2023
Enhanced Intraoperative Communication of Tumor Margins Using 3D Scanning and Mapping: The Computer-Aided Design Margin. The Laryngoscope\| PubMed ID: 36533659	2023
Ex vivo 3D scanning and specimen mapping in anatomic pathology. Journal of pathology informatics\| PubMed ID: 36687529	2023
Mapping Genetic Susceptibility to Stenosis in the Proximal Airway. The Laryngoscope\| PubMed ID: 37102306	2023
Augmented-Reality Surgery to Guide Head and Neck Cancer Re-resection: A Feasibility and Accuracy Study. Annals of surgical oncology\| PubMed ID: 37133570	2023
ASO Visual Abstract: Augmented Reality Surgery to Guide Head and Neck Cancer Re-resection: A Feasibility and Accuracy Study. Annals of surgical oncology\| PubMed ID: 37210454	2023
Virtual 3D Specimen Mapping in Head & Neck Oncologic Surgery. The Laryngoscope\| PubMed ID: 37466329	2023

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